Mettl6 (methyltransferase 6, tRNA N3-cytidine) - Rat Genome Database

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Gene: Mettl6 (methyltransferase 6, tRNA N3-cytidine) Chinchilla lanigera
Analyze
Symbol: Mettl6
Name: methyltransferase 6, tRNA N3-cytidine (Ensembl:methyltransferase like 6)
RGD ID: 9053433
Description: ENCODES a protein that exhibits enzyme binding (ortholog); tRNA (cytidine-3-)-methyltransferase activity (ortholog); INVOLVED IN tRNA methylation (ortholog); tRNA modification (ortholog); PARTICIPATES IN selenoamino acid metabolic pathway; ASSOCIATED WITH 3p deletion syndrome (ortholog); Breast Neoplasms (ortholog); genetic disease (ortholog); FOUND IN cytoplasm (ortholog); nucleus (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: methyltransferase 6, methylcytidine; methyltransferase like 6; methyltransferase-like protein 6
RGD Orthologs
Human
Mouse
Rat
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: ChiLan1.0 - Chinchilla ChiLan1.0 Assembly
Position:
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554301,909,404 - 1,933,239 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554301,910,557 - 1,933,249 (-)NCBIChiLan1.0ChiLan1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
cytoplasm  (ISO)
nucleus  (ISO)

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Transitive Annotation Pipeline Automated assignment of GO, PW and RDO ISO annotations across species

Genomics

Comparative Map Data
Mettl6
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554301,909,404 - 1,933,239 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554301,910,557 - 1,933,249 (-)NCBIChiLan1.0ChiLan1.0
METTL6
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38315,381,275 - 15,427,643 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl315,381,275 - 15,440,566 (-)EnsemblGRCh38hg38GRCh38
GRCh37315,451,267 - 15,469,051 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36315,426,381 - 15,444,046 (-)NCBINCBI36Build 36hg18NCBI36
Celera315,389,607 - 15,407,274 (-)NCBICelera
Cytogenetic Map3p25.1NCBI
HuRef315,386,707 - 15,404,381 (-)NCBIHuRef
CHM1_1315,402,252 - 15,419,927 (-)NCBICHM1_1
T2T-CHM13v2.0315,383,684 - 15,430,055 (-)NCBIT2T-CHM13v2.0
Mettl6
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391431,180,775 - 31,217,007 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1431,195,535 - 31,216,997 (-)EnsemblGRCm39 Ensembl
GRCm381431,463,715 - 31,495,059 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1431,473,578 - 31,495,040 (-)EnsemblGRCm38mm10GRCm38
MGSCv371432,291,984 - 32,308,163 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361430,307,807 - 30,323,986 (-)NCBIMGSCv36mm8
Celera1427,737,717 - 27,753,955 (-)NCBICelera
Cytogenetic Map14BNCBI
cM Map1419.12NCBI
Mettl6
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8166,667,971 - 6,705,385 (-)NCBIGRCr8
mRatBN7.2166,683,820 - 6,699,013 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl166,583,465 - 6,698,975 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx166,696,843 - 6,711,455 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0167,841,737 - 7,856,349 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0166,704,309 - 6,719,120 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0167,559,964 - 7,588,841 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl167,573,750 - 7,588,841 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0167,508,042 - 7,523,705 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4166,924,470 - 6,939,562 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1166,924,468 - 6,939,560 (-)NCBI
Celera168,491,500 - 8,506,251 (+)NCBICelera
Cytogenetic Map16p16NCBI
METTL6
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2215,366,067 - 15,412,690 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1315,370,831 - 15,417,454 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0315,306,890 - 15,353,505 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1315,643,545 - 15,690,253 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl315,643,545 - 15,690,238 (-)Ensemblpanpan1.1panPan2
SH3BP5
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12327,202,880 - 27,217,753 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2327,202,875 - 27,334,010 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2327,177,237 - 27,192,107 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02327,715,048 - 27,729,938 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2327,715,728 - 27,847,075 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12327,404,497 - 27,419,376 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02327,466,265 - 27,481,138 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02327,715,048 - 27,729,929 (+)NCBIUU_Cfam_GSD_1.0
Mettl6
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405118169,824,965 - 169,846,260 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049364732,963,466 - 2,985,634 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049364732,963,591 - 2,984,827 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
METTL6
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl132,638,389 - 2,654,836 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1132,638,972 - 2,654,845 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2132,565,960 - 2,581,817 (-)NCBISscrofa10.2Sscrofa10.2susScr3
METTL6
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11560,219,348 - 60,261,030 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1560,245,126 - 60,259,957 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604133,249,012 - 33,293,923 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Mettl6
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248225,254,938 - 5,282,742 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248225,253,659 - 5,349,292 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence


RefSeq Acc Id: ENSCLAT00000006794   ⟹   ENSCLAP00000006684
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_0049554301,909,404 - 1,933,239 (-)Ensembl
RefSeq Acc Id: XM_005387304   ⟹   XP_005387361
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_0049554301,910,557 - 1,933,239 (-)NCBI
Sequence:
RefSeq Acc Id: XM_005387305   ⟹   XP_005387362
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_0049554301,910,557 - 1,933,239 (-)NCBI
Sequence:
RefSeq Acc Id: XM_013515679   ⟹   XP_013371133
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_0049554301,914,847 - 1,933,249 (-)NCBI
Sequence:
RefSeq Acc Id: XM_013515680   ⟹   XP_013371134
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_0049554301,914,883 - 1,933,244 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_005387361 (Get FASTA)   NCBI Sequence Viewer  
  XP_005387362 (Get FASTA)   NCBI Sequence Viewer  
  XP_013371133 (Get FASTA)   NCBI Sequence Viewer  
  XP_013371134 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSCLAP00000006684
  ENSCLAP00000006684.1
RefSeq Acc Id: XP_005387361   ⟸   XM_005387304
- Peptide Label: isoform X1
- UniProtKB: A0A8C2UX82 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_005387362   ⟸   XM_005387305
- Peptide Label: isoform X1
- UniProtKB: A0A8C2UX82 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_013371133   ⟸   XM_013515679
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: XP_013371134   ⟸   XM_013515680
- Peptide Label: isoform X3
- Sequence:
RefSeq Acc Id: ENSCLAP00000006684   ⟸   ENSCLAT00000006794
Protein Domains
Methyltransferase type


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCLAG00000004710 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCLAT00000006794 ENTREZGENE
  ENSCLAT00000006794.1 UniProtKB/TrEMBL
Gene3D-CATH 3.40.50.150 UniProtKB/TrEMBL
InterPro Methyltransf_12 UniProtKB/TrEMBL
  MeTrfase UniProtKB/TrEMBL
  SAM-dependent_MTases UniProtKB/TrEMBL
NCBI Gene Mettl6 ENTREZGENE
PANTHER PTHR22809 UniProtKB/TrEMBL
  TRNA N(3)-METHYLCYTIDINE METHYLTRANSFERASE METTL6 UniProtKB/TrEMBL
Pfam Methyltransf_12 UniProtKB/TrEMBL
PIRSF Mettl2_prd UniProtKB/TrEMBL
Superfamily-SCOP SSF53335 UniProtKB/TrEMBL
UniProt A0A8C2UX82 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2023-05-30 Mettl6  methyltransferase 6, tRNA N3-cytidine  Mettl6  methyltransferase 6, methylcytidine  Symbol and/or name change 5135510 APPROVED
2021-05-26 Mettl6  methyltransferase 6, methylcytidine  Mettl6  methyltransferase like 6  Symbol and/or name change 5135510 APPROVED