Bdh1 (3-hydroxybutyrate dehydrogenase 1) - Rat Genome Database

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Gene: Bdh1 (3-hydroxybutyrate dehydrogenase 1) Chinchilla lanigera
Analyze
Symbol: Bdh1
Name: 3-hydroxybutyrate dehydrogenase 1
RGD ID: 9052304
Description: ENCODES a protein that exhibits 3-hydroxybutyrate dehydrogenase activity (ortholog); phospholipid binding (ortholog); INVOLVED IN adipose tissue development (ortholog); liver development (ortholog); response to cadmium ion (ortholog); PARTICIPATES IN forkhead class A signaling pathway; ketone bodies metabolic pathway; succinyl-CoA:3-oxoacid transferase deficiency pathway; ASSOCIATED WITH autistic disorder (ortholog); Chemical and Drug Induced Liver Injury (ortholog); COVID-19 (ortholog); FOUND IN mitochondrial inner membrane (ortholog); mitochondrion (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: 3-hydroxybutyrate dehydrogenase, type 1; D-beta-hydroxybutyrate dehydrogenase, mitochondrial
RGD Orthologs
Human
Mouse
Rat
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: ChiLan1.0 - Chinchilla ChiLan1.0 Assembly
Position:
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495542013,452,166 - 13,486,565 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495542013,454,379 - 13,486,700 (-)NCBIChiLan1.0ChiLan1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Transitive Annotation Pipeline Automated assignment of GO, PW and RDO ISO annotations across species
Additional References at PubMed
PMID:22301074  


Genomics

Comparative Map Data
Bdh1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495542013,452,166 - 13,486,565 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495542013,454,379 - 13,486,700 (-)NCBIChiLan1.0ChiLan1.0
BDH1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh383197,509,783 - 197,573,343 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl3197,509,783 - 197,573,323 (-)EnsemblGRCh38hg38GRCh38
GRCh373197,236,654 - 197,300,214 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 363198,721,051 - 198,784,591 (-)NCBINCBI36Build 36hg18NCBI36
Build 343198,726,756 - 198,788,504NCBI
Celera3195,829,052 - 195,891,752 (-)NCBICelera
Cytogenetic Map3q29NCBI
HuRef3194,539,341 - 194,602,169 (-)NCBIHuRef
CHM1_13197,207,633 - 197,271,017 (-)NCBICHM1_1
T2T-CHM13v2.03200,242,414 - 200,306,032 (-)NCBIT2T-CHM13v2.0
Bdh1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391631,241,115 - 31,277,719 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1631,241,098 - 31,277,719 (+)EnsemblGRCm39 Ensembl
GRCm381631,422,297 - 31,458,901 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1631,422,280 - 31,458,901 (+)EnsemblGRCm38mm10GRCm38
MGSCv371631,422,383 - 31,458,987 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361631,342,041 - 31,377,244 (+)NCBIMGSCv36mm8
Celera1631,928,539 - 31,964,764 (+)NCBICelera
Cytogenetic Map16B2NCBI
cM Map1621.74NCBI
Bdh1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81182,806,125 - 82,848,133 (-)NCBIGRCr8
mRatBN7.21169,302,534 - 69,343,173 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1169,302,534 - 69,337,671 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1178,139,549 - 78,174,678 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01170,799,406 - 70,827,976 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01169,828,637 - 69,863,770 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01172,577,547 - 72,619,435 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1172,578,533 - 72,614,176 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01175,651,886 - 75,693,764 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41171,130,561 - 71,165,695 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11171,188,149 - 71,223,284 (-)NCBI
Celera1168,723,790 - 68,758,851 (-)NCBICelera
Cytogenetic Map11q22NCBI
BDH1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22195,408,886 - 195,455,045 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan13195,416,692 - 195,462,850 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v03194,917,904 - 194,979,451 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.13204,797,765 - 204,862,387 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl3204,797,757 - 204,863,889 (-)Ensemblpanpan1.1panPan2
BDH1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13330,407,021 - 30,422,735 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl3330,406,338 - 30,436,366 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha3330,430,095 - 30,459,631 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.03330,656,076 - 30,686,162 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl3330,627,393 - 30,685,079 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.13330,449,912 - 30,479,577 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.03330,487,027 - 30,516,743 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.03331,107,916 - 31,137,803 (-)NCBIUU_Cfam_GSD_1.0
Bdh1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405602143,527,823 - 143,574,972 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936833367,710 - 410,139 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936833367,790 - 409,966 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
BDH1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl13132,605,489 - 132,645,937 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.113132,602,372 - 132,647,271 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.213142,184,212 - 142,203,863 (+)NCBISscrofa10.2Sscrofa10.2susScr3
BDH1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11589,678,844 - 89,741,848 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1589,707,046 - 89,742,434 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604163,463,989 - 63,508,519 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Bdh1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462473062,397,245 - 62,424,924 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462473062,397,242 - 62,466,172 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSCLAT00000019116   ⟹   ENSCLAP00000018931
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_00495542013,452,166 - 13,486,565 (-)Ensembl
RefSeq Acc Id: XM_005383174   ⟹   XP_005383231
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_00495542013,454,379 - 13,486,700 (-)NCBI
Sequence:
RefSeq Acc Id: XM_005383176   ⟹   XP_005383233
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_00495542013,454,379 - 13,486,565 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_005383231 (Get FASTA)   NCBI Sequence Viewer  
  XP_005383233 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSCLAP00000018931
  ENSCLAP00000018931.1
Reference Protein Sequences
RefSeq Acc Id: XP_005383231   ⟸   XM_005383174
- UniProtKB: A0A8C2VQ87 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_005383233   ⟸   XM_005383176
- UniProtKB: A0A8C2VQ87 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSCLAP00000018931   ⟸   ENSCLAT00000019116


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCLAG00000012964 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCLAT00000019116 ENTREZGENE
  ENSCLAT00000019116.1 UniProtKB/TrEMBL
Gene3D-CATH NAD(P)-binding Rossmann-like Domain UniProtKB/TrEMBL
InterPro NAD(P)-bd_dom_sf UniProtKB/TrEMBL
  Sc_DH/Rdtase_CS UniProtKB/TrEMBL
  SDR_fam UniProtKB/TrEMBL
NCBI Gene LOC102023364 ENTREZGENE
PANTHER D-BETA-HYDROXYBUTYRATE DEHYDROGENASE, MITOCHONDRIAL UniProtKB/TrEMBL
  SHORT-CHAIN DEHYDROGENASE/REDUCTASE FAMILY 9C UniProtKB/TrEMBL
Pfam adh_short UniProtKB/TrEMBL
PRINTS GDHRDH UniProtKB/TrEMBL
  SDRFAMILY UniProtKB/TrEMBL
PROSITE ADH_SHORT UniProtKB/TrEMBL
Superfamily-SCOP SSF51735 UniProtKB/TrEMBL
UniProt A0A8C2VQ87 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-12-20 Bdh1  3-hydroxybutyrate dehydrogenase 1    3-hydroxybutyrate dehydrogenase, type 1  Symbol and/or name change 5135510 APPROVED
2015-08-25 Bdh1  3-hydroxybutyrate dehydrogenase, type 1  LOC102023364  D-beta-hydroxybutyrate dehydrogenase, mitochondrial-like  Symbol and/or name change 5135510 APPROVED