Cbfa2t3 (CBFA2/RUNX1 partner transcriptional co-repressor 3) - Rat Genome Database

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Gene: Cbfa2t3 (CBFA2/RUNX1 partner transcriptional co-repressor 3) Chinchilla lanigera
Analyze
Symbol: Cbfa2t3
Name: CBFA2/RUNX1 partner transcriptional co-repressor 3
RGD ID: 9050992
Description: ENCODES a protein that exhibits chromatin binding (ortholog); INVOLVED IN granulocyte differentiation (ortholog); negative regulation of cell population proliferation (ortholog); negative regulation of DNA-templated transcription (ortholog); ASSOCIATED WITH 16Q24.3 Microdeletion Syndrome (ortholog); autosomal recessive chronic granulomatous disease 4 (ortholog); genetic disease (ortholog); FOUND IN nucleoplasm (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: CBFA2/RUNX1 translocation partner 3; core-binding factor, runt domain, alpha subunit 2; translocated to, 3
RGD Orthologs
Human
Mouse
Rat
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: ChiLan1.0 - Chinchilla ChiLan1.0 Assembly
Position:
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555412,724,312 - 2,777,592 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049555412,724,369 - 2,777,540 (-)NCBIChiLan1.0ChiLan1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
nucleoplasm  (ISO)

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Transitive Annotation Pipeline Automated assignment of GO, PW and RDO ISO annotations across species
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Cbfa2t3
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555412,724,312 - 2,777,592 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049555412,724,369 - 2,777,540 (-)NCBIChiLan1.0ChiLan1.0
CBFA2T3
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381688,874,858 - 88,977,207 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1688,874,858 - 88,977,207 (-)EnsemblGRCh38hg38GRCh38
GRCh371688,941,266 - 89,043,615 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361687,468,768 - 87,570,902 (-)NCBINCBI36Build 36hg18NCBI36
Build 341687,468,767 - 87,535,109NCBI
Celera1674,009,858 - 74,110,779 (-)NCBICelera
Cytogenetic Map16q24.3NCBI
HuRef1674,638,423 - 74,739,781 (-)NCBIHuRef
CHM1_11690,352,535 - 90,454,228 (-)NCBICHM1_1
T2T-CHM13v2.01694,945,216 - 95,054,578 (-)NCBIT2T-CHM13v2.0
Cbfa2t3
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm398123,351,875 - 123,426,069 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl8123,351,880 - 123,425,848 (-)EnsemblGRCm39 Ensembl
GRCm388122,625,136 - 122,699,332 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl8122,625,141 - 122,699,109 (-)EnsemblGRCm38mm10GRCm38
MGSCv378125,149,036 - 125,223,009 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv368125,516,082 - 125,585,069 (-)NCBIMGSCv36mm8
Celera8126,854,512 - 126,929,272 (-)NCBICelera
Cytogenetic Map8E1NCBI
cM Map871.93NCBI
Cbfa2t3
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81967,584,319 - 67,658,533 (-)NCBIGRCr8
mRatBN7.21950,679,897 - 50,750,028 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1950,680,729 - 50,749,610 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1957,475,521 - 57,544,200 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01958,155,645 - 58,224,522 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01960,374,139 - 60,442,815 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01955,438,409 - 55,510,652 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1955,441,572 - 55,510,460 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01966,145,151 - 66,218,784 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41952,908,942 - 52,980,399 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11952,913,754 - 53,012,742 (-)NCBI
Celera1949,920,125 - 49,988,577 (-)NCBICelera
Cytogenetic Map19q12NCBI
CBFA2T3
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21898,653,425 - 98,722,537 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan116104,565,877 - 104,634,627 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01669,592,293 - 69,662,321 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11689,246,545 - 89,347,435 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1689,246,545 - 89,347,435 (-)Ensemblpanpan1.1panPan2
CBFA2T3
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1564,432,291 - 64,518,905 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl564,431,843 - 64,519,528 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha564,443,579 - 64,529,331 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0564,652,241 - 64,738,015 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl564,652,160 - 64,738,015 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1564,678,376 - 64,764,153 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0564,510,060 - 64,595,977 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0564,915,902 - 65,001,888 (+)NCBIUU_Cfam_GSD_1.0
Cbfa2t3
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440934925,056,311 - 25,121,988 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936641810,074 - 875,534 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936641857,483 - 875,527 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
CBFA2T3
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl6779,366 - 853,822 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.16779,164 - 854,449 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.261,022,699 - 1,044,424 (+)NCBISscrofa10.2Sscrofa10.2susScr3
CBFA2T3
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1574,260,516 - 74,361,268 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl574,263,375 - 74,289,875 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660471,300,151 - 1,364,549 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Cbfa2t3
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_004624746716,836 - 773,169 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_004624746716,848 - 773,169 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSCLAT00000001166   ⟹   ENSCLAP00000001125
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_0049555412,724,312 - 2,777,592 (-)Ensembl
RefSeq Acc Id: ENSCLAT00000001167   ⟹   ENSCLAP00000001126
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_0049555412,724,312 - 2,777,592 (-)Ensembl
RefSeq Acc Id: ENSCLAT00000001168   ⟹   ENSCLAP00000001127
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_0049555412,724,312 - 2,749,464 (-)Ensembl
RefSeq Acc Id: XM_005411026   ⟹   XP_005411083
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_0049555412,724,369 - 2,777,540 (-)NCBI
Sequence:
RefSeq Acc Id: XM_005411029   ⟹   XP_005411086
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_0049555412,724,369 - 2,749,464 (-)NCBI
Sequence:
RefSeq Acc Id: XM_005411030   ⟹   XP_005411087
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_0049555412,724,369 - 2,738,811 (-)NCBI
Sequence:
RefSeq Acc Id: XM_013508004   ⟹   XP_013363458
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_0049555412,724,369 - 2,741,345 (-)NCBI
Sequence:
RefSeq Acc Id: XM_013508006   ⟹   XP_013363460
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_0049555412,724,369 - 2,741,345 (-)NCBI
Sequence:
Reference Protein Sequences
RefSeq Acc Id: XP_005411083   ⟸   XM_005411026
- Peptide Label: isoform X2
- UniProtKB: A0A8C2YIH2 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_005411086   ⟸   XM_005411029
- Peptide Label: isoform X4
- UniProtKB: A0A8C2UJL5 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_005411087   ⟸   XM_005411030
- Peptide Label: isoform X5
- Sequence:
RefSeq Acc Id: XP_013363460   ⟸   XM_013508006
- Peptide Label: isoform X3
- UniProtKB: A0A8C2YIH7 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_013363458   ⟸   XM_013508004
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: ENSCLAP00000001127   ⟸   ENSCLAT00000001168
RefSeq Acc Id: ENSCLAP00000001126   ⟸   ENSCLAT00000001167
RefSeq Acc Id: ENSCLAP00000001125   ⟸   ENSCLAT00000001166
Protein Domains
MYND-type   TAFH


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCLAG00000000863 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCLAT00000001166 ENTREZGENE
  ENSCLAT00000001166.1 UniProtKB/TrEMBL
  ENSCLAT00000001167 ENTREZGENE
  ENSCLAT00000001167.1 UniProtKB/TrEMBL
  ENSCLAT00000001168 ENTREZGENE
  ENSCLAT00000001168.1 UniProtKB/TrEMBL
Gene3D-CATH 1.20.120.1110 UniProtKB/TrEMBL
  6.10.140.2220 UniProtKB/TrEMBL
  6.10.250.230 UniProtKB/TrEMBL
InterPro CBFA2T1/2/3 UniProtKB/TrEMBL
  CBFA2T3 UniProtKB/TrEMBL
  NHR2 UniProtKB/TrEMBL
  TAFH/NHR1_dom_sf UniProtKB/TrEMBL
  TAFH_NHR1 UniProtKB/TrEMBL
  Znf_MYND UniProtKB/TrEMBL
NCBI Gene Cbfa2t3 ENTREZGENE
PANTHER PROTEIN CBFA2T3 UniProtKB/TrEMBL
  PTHR10379 UniProtKB/TrEMBL
Pfam NHR2 UniProtKB/TrEMBL
  TAFH UniProtKB/TrEMBL
  zf-MYND UniProtKB/TrEMBL
PRINTS ETOFAMILY UniProtKB/TrEMBL
  MTG16PROTEIN UniProtKB/TrEMBL
PROSITE TAFH UniProtKB/TrEMBL
  ZF_MYND_1 UniProtKB/TrEMBL
  ZF_MYND_2 UniProtKB/TrEMBL
SMART TAFH UniProtKB/TrEMBL
Superfamily-SCOP HIT/MYND zinc finger-like UniProtKB/TrEMBL
  SSF158553 UniProtKB/TrEMBL
UniProt A0A8C2UJL5 ENTREZGENE, UniProtKB/TrEMBL
  A0A8C2YIH2 ENTREZGENE, UniProtKB/TrEMBL
  A0A8C2YIH7 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2019-05-21 Cbfa2t3  CBFA2/RUNX1 partner transcriptional co-repressor 3  Cbfa2t3  CBFA2/RUNX1 translocation partner 3  Symbol and/or name change 5135510 APPROVED
2016-08-03 Cbfa2t3  CBFA2/RUNX1 translocation partner 3    core-binding factor, runt domain, alpha subunit 2; translocated to, 3  Symbol and/or name change 5135510 APPROVED