Emc2 (ER membrane protein complex subunit 2) - Rat Genome Database

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Gene: Emc2 (ER membrane protein complex subunit 2) Chinchilla lanigera
Analyze
Symbol: Emc2
Name: ER membrane protein complex subunit 2
RGD ID: 9049014
Description: ENCODES a protein that exhibits membrane insertase activity (ortholog); INVOLVED IN protein insertion into ER membrane by stop-transfer membrane-anchor sequence (ortholog); tail-anchored membrane protein insertion into ER membrane (ortholog); ASSOCIATED WITH genetic disease (ortholog); FOUND IN cytoplasm (ortholog); EMC complex (ortholog); endoplasmic reticulum (ortholog)
Type: protein-coding
RefSeq Status: MODEL
RGD Orthologs
Human
Mouse
Rat
Bonobo
Dog
Squirrel
Pig
Green Monkey
Alliance Genes
More Info more info ...
Latest Assembly: ChiLan1.0 - Chinchilla ChiLan1.0 Assembly
Position:
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541731,019,403 - 31,051,976 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495541731,019,389 - 31,048,143 (+)NCBIChiLan1.0ChiLan1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Transitive Annotation Pipeline Automated assignment of GO, PW and RDO ISO annotations across species
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Emc2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541731,019,403 - 31,051,976 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495541731,019,389 - 31,048,143 (+)NCBIChiLan1.0ChiLan1.0
EMC2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh388108,443,624 - 108,489,196 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl8108,443,601 - 108,489,196 (+)EnsemblGRCh38hg38GRCh38
GRCh378109,455,853 - 109,501,425 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 368109,525,029 - 109,568,312 (+)NCBINCBI36Build 36hg18NCBI36
Build 348109,525,028 - 109,568,312NCBI
Celera8105,642,999 - 105,686,297 (+)NCBICelera
Cytogenetic Map8q23.1NCBI
HuRef8104,777,276 - 104,820,161 (+)NCBIHuRef
CHM1_18109,496,105 - 109,539,394 (+)NCBICHM1_1
T2T-CHM13v2.08109,572,105 - 109,617,653 (+)NCBIT2T-CHM13v2.0
Emc2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391543,340,603 - 43,391,174 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1543,340,625 - 43,391,159 (+)EnsemblGRCm39 Ensembl
GRCm381543,477,229 - 43,527,777 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1543,477,229 - 43,527,763 (+)EnsemblGRCm38mm10GRCm38
MGSCv371543,308,775 - 43,359,323 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361543,307,303 - 43,357,851 (+)NCBIMGSCv36mm8
Celera1543,953,653 - 43,997,401 (+)NCBICelera
Cytogenetic Map15B3.2NCBI
cM Map1516.75NCBI
Emc2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8776,471,899 - 76,508,866 (+)NCBIGRCr8
mRatBN7.2774,587,196 - 74,624,163 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl774,587,175 - 74,625,189 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx776,430,651 - 76,467,739 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0778,633,156 - 78,670,238 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0778,501,148 - 78,538,291 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0782,338,639 - 82,377,389 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl782,338,663 - 82,377,109 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0782,349,425 - 82,385,901 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4779,265,488 - 79,300,317 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1779,286,206 - 79,323,421 (+)NCBI
Celera771,581,687 - 71,618,534 (+)NCBICelera
Cytogenetic Map7q31NCBI
EMC2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v27125,819,488 - 125,865,710 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan18101,342,846 - 101,389,664 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v08105,095,815 - 105,144,333 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.18107,243,288 - 107,292,469 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl8107,243,311 - 107,292,469 (+)Ensemblpanpan1.1panPan2
EMC2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1139,069,782 - 9,224,255 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha139,047,943 - 9,448,642 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0139,342,945 - 9,744,989 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl139,342,930 - 9,388,166 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1139,085,878 - 9,487,856 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0139,210,613 - 9,612,673 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0139,291,379 - 9,693,503 (+)NCBIUU_Cfam_GSD_1.0
Emc2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440530328,927,949 - 28,971,914 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493647036,350,969 - 36,398,008 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493647036,354,048 - 36,397,977 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
EMC2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl429,017,517 - 29,079,270 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1428,981,118 - 29,079,270 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2431,452,650 - 31,473,612 (-)NCBISscrofa10.2Sscrofa10.2susScr3
EMC2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.18103,159,689 - 103,209,374 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl8103,159,754 - 103,212,214 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366603937,371,382 - 37,421,395 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0


Expression


Sequence


RefSeq Acc Id: ENSCLAT00000006460   ⟹   ENSCLAP00000006355
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_00495541731,019,403 - 31,051,976 (+)Ensembl
RefSeq Acc Id: ENSCLAT00000006461   ⟹   ENSCLAP00000006356
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_00495541731,019,995 - 31,047,476 (+)Ensembl
RefSeq Acc Id: XM_005381969   ⟹   XP_005382026
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_00495541731,019,389 - 31,048,143 (+)NCBI
Sequence:
RefSeq Acc Id: XM_005381970   ⟹   XP_005382027
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_00495541731,019,403 - 31,047,476 (+)NCBI
Sequence:
RefSeq Acc Id: XM_005381971   ⟹   XP_005382028
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_00495541731,022,387 - 31,048,143 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_005382026 (Get FASTA)   NCBI Sequence Viewer  
  XP_005382027 (Get FASTA)   NCBI Sequence Viewer  
  XP_005382028 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSCLAP00000006355
  ENSCLAP00000006355.1
  ENSCLAP00000006356.1
RefSeq Acc Id: XP_005382026   ⟸   XM_005381969
- Peptide Label: isoform X1
- UniProtKB: A0A8C2UVE1 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_005382027   ⟸   XM_005381970
- Peptide Label: isoform X2
- UniProtKB: A0A8C2UVE1 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_005382028   ⟸   XM_005381971
- Peptide Label: isoform X3
- Sequence:
RefSeq Acc Id: ENSCLAP00000006356   ⟸   ENSCLAT00000006461
RefSeq Acc Id: ENSCLAP00000006355   ⟸   ENSCLAT00000006460


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCLAG00000004492 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCLAT00000006460 ENTREZGENE
  ENSCLAT00000006460.1 UniProtKB/TrEMBL
  ENSCLAT00000006461.1 UniProtKB/TrEMBL
Gene3D-CATH 1.25.40.10 UniProtKB/TrEMBL
InterPro EMC2-like UniProtKB/TrEMBL
  TPR-like_helical_dom_sf UniProtKB/TrEMBL
  TPR_repeat UniProtKB/TrEMBL
NCBI Gene Emc2 ENTREZGENE
PANTHER ER MEMBRANE PROTEIN COMPLEX SUBUNIT 2 UniProtKB/TrEMBL
  PTHR12760 UniProtKB/TrEMBL
Pfam TPR_19 UniProtKB/TrEMBL
PROSITE TPR UniProtKB/TrEMBL
SMART TPR UniProtKB/TrEMBL
Superfamily-SCOP SSF48452 UniProtKB/TrEMBL
UniProt A0A8C2UVD7_CHILA UniProtKB/TrEMBL
  A0A8C2UVE1 ENTREZGENE, UniProtKB/TrEMBL