Adamts15 (ADAM metallopeptidase with thrombospondin type 1 motif 15) - Rat Genome Database

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Gene: Adamts15 (ADAM metallopeptidase with thrombospondin type 1 motif 15) Chinchilla lanigera
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Symbol: Adamts15
Name: ADAM metallopeptidase with thrombospondin type 1 motif 15
RGD ID: 9048916
Description: ENCODES a protein that exhibits endopeptidase activity (ortholog); extracellular matrix binding (ortholog); heparin binding (ortholog); INVOLVED IN extracellular matrix disassembly (ortholog); myoblast fusion (ortholog); ASSOCIATED WITH Chromosome 11, Partial Trisomy 11q (ortholog); Distal Arthrogryposis Type 12 (ortholog); Dwarfism (ortholog); FOUND IN cell surface (ortholog); extracellular space (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: A disintegrin and metalloproteinase with thrombospondin motifs 15; ADAM metallopeptidase with thrombospondin type 1 motif, 15
RGD Orthologs
Human
Mouse
Rat
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: ChiLan1.0 - Chinchilla ChiLan1.0 Assembly
Position:
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541231,336,759 - 31,360,957 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495541231,336,759 - 31,360,905 (+)NCBIChiLan1.0ChiLan1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Transitive Annotation Pipeline Automated assignment of GO, PW and RDO ISO annotations across species
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Adamts15
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541231,336,759 - 31,360,957 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495541231,336,759 - 31,360,905 (+)NCBIChiLan1.0ChiLan1.0
ADAMTS15
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh3811130,448,645 - 130,476,645 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl11130,448,645 - 130,476,645 (+)EnsemblGRCh38hg38GRCh38
GRCh3711130,318,540 - 130,346,540 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 3611129,824,079 - 129,848,926 (+)NCBINCBI36Build 36hg18NCBI36
Build 3411129,824,078 - 129,848,926NCBI
Celera11127,487,765 - 127,515,431 (+)NCBICelera
Cytogenetic Map11q24.3NCBI
HuRef11126,273,179 - 126,300,793 (+)NCBIHuRef
CHM1_111130,204,589 - 130,232,182 (+)NCBICHM1_1
T2T-CHM13v2.011130,484,367 - 130,513,939 (+)NCBIT2T-CHM13v2.0
Adamts15
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39930,810,451 - 30,833,853 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl930,810,451 - 30,833,748 (-)EnsemblGRCm39 Ensembl
GRCm38930,899,155 - 30,922,452 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl930,899,155 - 30,922,452 (-)EnsemblGRCm38mm10GRCm38
MGSCv37930,706,740 - 30,730,037 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36930,648,720 - 30,672,017 (-)NCBIMGSCv36mm8
Celera928,160,230 - 28,183,951 (-)NCBICelera
Cytogenetic Map9A4NCBI
cM Map916.45NCBI
Adamts15
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8837,566,064 - 37,589,446 (-)NCBIGRCr8
mRatBN7.2829,307,864 - 29,331,249 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl829,307,865 - 29,331,249 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx833,373,681 - 33,397,067 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0831,668,067 - 31,691,453 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0829,539,477 - 29,562,855 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0831,977,001 - 32,000,378 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl831,977,001 - 32,000,378 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0832,003,564 - 32,026,941 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4830,683,281 - 30,706,659 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1830,694,936 - 30,730,948 (-)NCBI
Celera830,770,381 - 30,793,785 (-)NCBICelera
Cytogenetic Map8q13NCBI
ADAMTS15
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v29131,128,281 - 131,158,391 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan111132,238,956 - 132,269,078 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v011125,264,129 - 125,291,655 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.111129,154,895 - 129,182,326 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl11129,154,895 - 129,182,326 (+)Ensemblpanpan1.1panPan2
ADAMTS15
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.154,457,879 - 4,480,210 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl54,457,959 - 4,479,875 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha54,518,959 - 4,541,178 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.054,418,980 - 4,441,203 (-)NCBIROS_Cfam_1.0
UMICH_Zoey_3.154,453,486 - 4,475,681 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.054,461,716 - 4,483,990 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.054,488,970 - 4,511,210 (-)NCBIUU_Cfam_GSD_1.0
Adamts15
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024404947112,489,450 - 112,514,584 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365721,936,529 - 1,960,800 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365721,935,780 - 1,960,888 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ADAMTS15
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl957,127,442 - 57,152,547 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1957,127,527 - 57,152,550 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2963,398,142 - 63,422,838 (+)NCBISscrofa10.2Sscrofa10.2susScr3
ADAMTS15
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11121,510,798 - 121,538,715 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1121,510,849 - 121,535,609 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660434,571,578 - 4,599,685 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Adamts15
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248124,814,644 - 4,839,944 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248124,814,753 - 4,839,843 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence


RefSeq Acc Id: ENSCLAT00000023333   ⟹   ENSCLAP00000023113
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_00495541231,336,759 - 31,360,957 (+)Ensembl
RefSeq Acc Id: XM_005378569   ⟹   XP_005378626
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_00495541231,336,759 - 31,360,905 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_005378626 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSCLAP00000023113
  ENSCLAP00000023113.1
RefSeq Acc Id: XP_005378626   ⟸   XM_005378569
- UniProtKB: A0A8C2W2S3 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSCLAP00000023113   ⟸   ENSCLAT00000023333
Protein Domains
Peptidase M12B


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCLAG00000015866 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCLAT00000023333 ENTREZGENE
  ENSCLAT00000023333.1 UniProtKB/TrEMBL
Gene3D-CATH 2.20.100.10 UniProtKB/TrEMBL
  2.60.120.830 UniProtKB/TrEMBL
  3.40.1620.60 UniProtKB/TrEMBL
  3.40.390.10 UniProtKB/TrEMBL
InterPro ADAM_Cys-rich UniProtKB/TrEMBL
  ADAMTS/ADAMTS-like UniProtKB/TrEMBL
  ADAMTS_CR_2 UniProtKB/TrEMBL
  ADAMTS_CR_3 UniProtKB/TrEMBL
  ADAMTS_spacer1 UniProtKB/TrEMBL
  MetalloPept_cat_dom_sf UniProtKB/TrEMBL
  Pept_M12B_ADAM-TS8 UniProtKB/TrEMBL
  Peptidase_M12B UniProtKB/TrEMBL
  Peptidase_M12B_N UniProtKB/TrEMBL
  TSP1_rpt UniProtKB/TrEMBL
  TSP1_rpt_sf UniProtKB/TrEMBL
NCBI Gene Adamts15 ENTREZGENE
PANTHER A DISINTEGRIN AND METALLOPROTEINASE WITH THROMBOSPONDIN MOTIFS 15 UniProtKB/TrEMBL
  ADAMTS A DISINTEGRIN AND METALLOPROTEASE WITH THROMBOSPONDIN MOTIFS PROTEASE UniProtKB/TrEMBL
Pfam ADAM_CR_2 UniProtKB/TrEMBL
  ADAM_CR_3 UniProtKB/TrEMBL
  ADAM_spacer1 UniProtKB/TrEMBL
  Pep_M12B_propep UniProtKB/TrEMBL
  Reprolysin UniProtKB/TrEMBL
  TSP1_ADAMTS UniProtKB/TrEMBL
  TSP_1 UniProtKB/TrEMBL
PRINTS ADAMTS8 UniProtKB/TrEMBL
  ADAMTSFAMILY UniProtKB/TrEMBL
PROSITE ADAM_MEPRO UniProtKB/TrEMBL
  TSP1 UniProtKB/TrEMBL
SMART ACR UniProtKB/TrEMBL
  TSP1 UniProtKB/TrEMBL
Superfamily-SCOP Metalloproteases ('zincins'), catalytic domain UniProtKB/TrEMBL
  SSF82895 UniProtKB/TrEMBL
UniProt A0A8C2W2S3 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-08-16 Adamts15  ADAM metallopeptidase with thrombospondin type 1 motif 15    ADAM metallopeptidase with thrombospondin type 1 motif, 15  Symbol and/or name change 5135510 APPROVED