Ntrk1 (neurotrophic receptor tyrosine kinase 1) - Rat Genome Database

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Gene: Ntrk1 (neurotrophic receptor tyrosine kinase 1) Chinchilla lanigera
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Symbol: Ntrk1
Name: neurotrophic receptor tyrosine kinase 1
RGD ID: 9045991
Description: ENCODES a protein that exhibits GPI-linked ephrin receptor activity (ortholog); identical protein binding (ortholog); kinase binding (ortholog); INVOLVED IN aging (ortholog); axon guidance (ortholog); axonogenesis involved in innervation (ortholog); ASSOCIATED WITH Alzheimer's disease (ortholog); asthma (ortholog); atopic dermatitis (ortholog); FOUND IN axon (ortholog); cell surface (ortholog); cytoplasm (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Also known as: high affinity nerve growth factor receptor; neurotrophic tyrosine kinase, receptor, type 1
RGD Orthologs
Human
Mouse
Rat
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: ChiLan1.0 - Chinchilla ChiLan1.0 Assembly
Position:
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555452,929,704 - 2,947,579 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049555452,929,704 - 2,947,579 (+)NCBIChiLan1.0ChiLan1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process
aging  (ISO)
axon guidance  (ISO)
axonogenesis involved in innervation  (ISO)
B cell differentiation  (ISO)
behavioral response to formalin induced pain  (ISO)
cellular response to amyloid-beta  (ISO)
cellular response to nerve growth factor stimulus  (ISO)
cellular response to nicotine  (ISO)
circadian rhythm  (ISO)
detection of mechanical stimulus involved in sensory perception of pain  (ISO)
detection of temperature stimulus involved in sensory perception of pain  (ISO)
innervation  (ISO)
learning or memory  (ISO)
mechanoreceptor differentiation  (ISO)
negative regulation of cell population proliferation  (ISO)
negative regulation of neuron apoptotic process  (ISO)
negative regulation of neuron death  (ISO)
nerve growth factor signaling pathway  (ISO)
nervous system development  (ISO)
neuron development  (ISO)
neuron projection development  (ISO)
neurotrophin TRK receptor signaling pathway  (ISO)
olfactory nerve development  (ISO)
peptidyl-tyrosine autophosphorylation  (ISO)
peptidyl-tyrosine phosphorylation  (ISO)
positive regulation of angiogenesis  (ISO)
positive regulation of ERK1 and ERK2 cascade  (ISO)
positive regulation of GTPase activity  (ISO)
positive regulation of neuron projection development  (ISO)
positive regulation of NF-kappaB transcription factor activity  (ISO)
positive regulation of programmed cell death  (ISO)
positive regulation of protein phosphorylation  (ISO)
positive regulation of Ras protein signal transduction  (ISO)
positive regulation of synapse assembly  (ISO)
positive regulation of synaptic transmission, glutamatergic  (ISO)
programmed cell death involved in cell development  (ISO)
protein autophosphorylation  (ISO)
protein phosphorylation  (ISO)
response to activity  (ISO)
response to axon injury  (ISO)
response to drug  (ISO)
response to electrical stimulus  (ISO)
response to ethanol  (ISO)
response to hydrostatic pressure  (ISO)
response to nicotine  (ISO)
response to nutrient levels  (ISO)
response to radiation  (ISO)
sensory perception of pain  (ISO)
Sertoli cell development  (ISO)
sympathetic nervous system development  (ISO)

Cellular Component

References


Genomics

Comparative Map Data
Ntrk1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555452,929,704 - 2,947,579 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049555452,929,704 - 2,947,579 (+)NCBIChiLan1.0ChiLan1.0
NTRK1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl1156,815,640 - 156,881,850 (+)EnsemblGRCh38hg38GRCh38
GRCh381156,815,750 - 156,881,850 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh371156,785,542 - 156,851,642 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361155,052,166 - 155,118,266 (+)NCBINCBI36hg18NCBI36
Build 341153,643,743 - 153,664,715NCBI
Celera1129,856,788 - 129,922,861 (+)NCBI
Cytogenetic Map1q23.1NCBI
HuRef1128,143,945 - 128,209,968 (+)NCBIHuRef
CHM1_11158,181,737 - 158,247,825 (+)NCBICHM1_1
Ntrk1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39387,685,551 - 87,702,549 (-)NCBIGRCm39mm39
GRCm39 Ensembl387,685,551 - 87,702,469 (-)Ensembl
GRCm38387,778,244 - 87,795,242 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl387,778,244 - 87,795,162 (-)EnsemblGRCm38mm10GRCm38
MGSCv37387,582,166 - 87,599,084 (-)NCBIGRCm37mm9NCBIm37
MGSCv36387,864,171 - 87,881,089 (-)NCBImm8
Celera387,816,061 - 87,832,981 (-)NCBICelera
Cytogenetic Map3F1NCBI
cM Map338.62NCBI
Ntrk1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.22173,236,961 - 173,253,806 (-)NCBI
Rnor_6.0 Ensembl2187,143,568 - 187,160,373 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.02187,143,568 - 187,160,373 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.02206,548,566 - 206,565,385 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.42179,838,740 - 179,855,545 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.12179,788,845 - 179,805,651 (-)NCBI
Celera2167,186,754 - 167,203,558 (-)NCBICelera
Cytogenetic Map2q34NCBI
NTRK1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1741,140,931 - 41,159,326 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl741,140,879 - 41,159,288 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha740,627,981 - 40,646,334 (-)NCBI
ROS_Cfam_1.0741,003,176 - 41,021,761 (-)NCBI
UMICH_Zoey_3.1740,785,455 - 40,803,799 (-)NCBI
UNSW_CanFamBas_1.0740,838,471 - 40,856,834 (-)NCBI
UU_Cfam_GSD_1.0741,121,978 - 41,140,332 (-)NCBI
Ntrk1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440505826,971,788 - 26,991,308 (+)NCBI
SpeTri2.0NW_0049365806,002,168 - 6,021,690 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
NTRK1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl493,219,516 - 93,237,930 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1493,219,509 - 93,237,944 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.24101,791,572 - 101,810,021 (-)NCBISscrofa10.2Sscrofa10.2susScr3
NTRK1
(Chlorocebus sabaeus - African green monkey)
Vervet AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1206,987,903 - 7,027,381 (-)NCBI
ChlSab1.1 Ensembl206,987,905 - 7,008,670 (-)Ensembl
Ntrk1
(Heterocephalus glaber - naked mole-rat)
Molerat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046248851,989,027 - 2,005,474 (+)NCBI


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSCLAT00000006080   ⟹   ENSCLAP00000005977
RefSeq Status:
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_0049555452,929,704 - 2,947,579 (+)Ensembl
RefSeq Acc Id: XM_005411713   ⟹   XP_005411770
RefSeq Status:
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_0049555452,929,704 - 2,947,579 (+)NCBI
Sequence:
RefSeq Acc Id: XM_005411714   ⟹   XP_005411771
RefSeq Status:
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_0049555452,929,704 - 2,947,579 (+)NCBI
Sequence:
RefSeq Acc Id: XM_005411716   ⟹   XP_005411773
RefSeq Status:
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_0049555452,929,704 - 2,944,724 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_005411770 (Get FASTA)   NCBI Sequence Viewer  
  XP_005411771 (Get FASTA)   NCBI Sequence Viewer  
  XP_005411773 (Get FASTA)   NCBI Sequence Viewer  
Reference Sequences
RefSeq Acc Id: XP_005411770   ⟸   XM_005411713
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_005411771   ⟸   XM_005411714
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: XP_005411773   ⟸   XM_005411716
- Peptide Label: isoform X3
- Sequence:
RefSeq Acc Id: ENSCLAP00000005977   ⟸   ENSCLAT00000006080


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCLAG00000004234 Ensembl, ENTREZGENE
Ensembl Protein ENSCLAP00000005977 ENTREZGENE
Ensembl Transcript ENSCLAT00000006080 ENTREZGENE
NCBI Gene Ntrk1 ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-08-03 Ntrk1  neurotrophic receptor tyrosine kinase 1    neurotrophic tyrosine kinase, receptor, type 1  Symbol and/or name change 5135510 APPROVED