Sec14l2 (SEC14 like lipid binding 2) - Rat Genome Database

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Gene: Sec14l2 (SEC14 like lipid binding 2) Chinchilla lanigera
Analyze
Symbol: Sec14l2
Name: SEC14 like lipid binding 2
RGD ID: 9042655
Description: ENCODES a protein that exhibits enzyme activator activity (ortholog); transferase activity, transferring alkyl or aryl (other than methyl) groups (ortholog); INVOLVED IN positive regulation of cholesterol biosynthetic process (ortholog); ASSOCIATED WITH genetic disease (ortholog); FOUND IN cytosol (ortholog); nucleoplasm (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: SEC14-like 2; SEC14-like lipid binding 2; SEC14-like protein 2
RGD Orthologs
Human
Mouse
Rat
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: ChiLan1.0 - Chinchilla ChiLan1.0 Assembly
Position:
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554554,636,709 - 4,660,058 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554554,637,062 - 4,660,064 (+)NCBIChiLan1.0ChiLan1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
cytosol  (ISO)
nucleoplasm  (ISO)

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Transitive Annotation Pipeline Automated assignment of GO, PW and RDO ISO annotations across species
Additional References at PubMed
PMID:30032202  


Genomics

Comparative Map Data
Sec14l2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554554,636,709 - 4,660,058 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554554,637,062 - 4,660,064 (+)NCBIChiLan1.0ChiLan1.0
SEC14L2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382230,397,018 - 30,425,303 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2230,396,941 - 30,425,303 (+)EnsemblGRCh38hg38GRCh38
GRCh372230,793,007 - 30,821,291 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 362229,122,933 - 29,149,828 (+)NCBINCBI36Build 36hg18NCBI36
Build 342229,117,486 - 29,144,382NCBI
Celera2214,592,619 - 14,620,968 (+)NCBICelera
Cytogenetic Map22q12.2NCBI
HuRef2213,754,252 - 13,782,494 (+)NCBIHuRef
CHM1_12230,752,095 - 30,780,850 (+)NCBICHM1_1
T2T-CHM13v2.02230,860,348 - 30,888,644 (+)NCBIT2T-CHM13v2.0
Sec14l2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39114,047,039 - 4,068,729 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl114,047,039 - 4,073,415 (-)EnsemblGRCm39 Ensembl
GRCm38114,097,039 - 4,118,729 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl114,097,039 - 4,123,415 (-)EnsemblGRCm38mm10GRCm38
MGSCv37113,997,042 - 4,018,732 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36113,997,042 - 4,018,732 (-)NCBIMGSCv36mm8
Celera114,592,969 - 4,615,073 (-)NCBICelera
Cytogenetic Map11A1NCBI
cM Map112.87NCBI
Sec14l2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81483,197,384 - 83,222,059 (-)NCBIGRCr8
mRatBN7.21478,973,805 - 78,998,480 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1478,973,808 - 78,993,788 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1483,414,439 - 83,434,399 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01484,654,518 - 84,674,478 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01481,100,444 - 81,120,373 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01484,335,594 - 84,360,354 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1484,335,597 - 84,355,528 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01485,017,259 - 85,041,827 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41484,728,484 - 84,748,418 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11484,747,628 - 84,767,563 (-)NCBI
Celera1477,884,808 - 77,904,737 (-)NCBICelera
Cytogenetic Map14q21NCBI
SEC14L2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22340,363,958 - 40,390,569 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12243,062,594 - 43,090,650 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02211,432,608 - 11,460,973 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12229,234,162 - 29,261,937 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2229,234,162 - 29,261,937 (+)Ensemblpanpan1.1panPan2
LOC477539
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12623,542,555 - 23,563,579 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2623,413,626 - 23,433,383 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02623,926,643 - 23,946,387 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2623,926,486 - 23,946,800 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12623,628,117 - 23,647,869 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02623,890,926 - 23,910,663 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02623,951,320 - 23,971,099 (+)NCBIUU_Cfam_GSD_1.0
Sec14l2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405118116,457,964 - 116,479,252 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936904253,436 - 276,897 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936904254,979 - 276,267 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
SEC14L2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1447,370,055 - 47,392,499 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11447,369,663 - 47,391,335 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21450,454,593 - 50,475,848 (+)NCBISscrofa10.2Sscrofa10.2susScr3
SEC14L2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11913,276,712 - 13,302,737 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1913,276,913 - 13,305,003 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666045112,841,789 - 112,869,976 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Sec14l2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247476,719,498 - 6,742,794 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247476,719,549 - 6,742,794 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSCLAT00000017115   ⟹   ENSCLAP00000016949
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_0049554554,636,709 - 4,660,058 (+)Ensembl
RefSeq Acc Id: XM_005396260   ⟹   XP_005396317
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_0049554554,637,062 - 4,660,064 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_005396317 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSCLAP00000016949
  ENSCLAP00000016949.1
Reference Protein Sequences
RefSeq Acc Id: XP_005396317   ⟸   XM_005396260
- UniProtKB: A0A8C2YR09 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSCLAP00000016949   ⟸   ENSCLAT00000017115
Protein Domains
CRAL-TRIO   GOLD


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCLAG00000011633 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCLAT00000017115 ENTREZGENE
  ENSCLAT00000017115.1 UniProtKB/TrEMBL
Gene3D-CATH 3.40.525.10 UniProtKB/TrEMBL
  GOLD domain UniProtKB/TrEMBL
InterPro CRAL-TRIO_dom UniProtKB/TrEMBL
  CRAL-TRIO_dom_sf UniProtKB/TrEMBL
  CRAL/TRIO_N_dom UniProtKB/TrEMBL
  CRAL/TRIO_N_dom_sf UniProtKB/TrEMBL
  GOLD_dom UniProtKB/TrEMBL
  GOLD_dom_sf UniProtKB/TrEMBL
NCBI Gene Sec14l2 ENTREZGENE
PANTHER SEC14 RELATED PROTEIN UniProtKB/TrEMBL
  SEC14-LIKE PROTEIN 2 UniProtKB/TrEMBL
Pfam CRAL_TRIO UniProtKB/TrEMBL
  CRAL_TRIO_N UniProtKB/TrEMBL
PRINTS CRETINALDHBP UniProtKB/TrEMBL
PROSITE CRAL_TRIO UniProtKB/TrEMBL
  GOLD UniProtKB/TrEMBL
SMART CRAL_TRIO_N UniProtKB/TrEMBL
  SEC14 UniProtKB/TrEMBL
Superfamily-SCOP SSF101576 UniProtKB/TrEMBL
  SSF46938 UniProtKB/TrEMBL
  SSF52087 UniProtKB/TrEMBL
UniProt A0A8C2YR09 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-08-03 Sec14l2  SEC14 like lipid binding 2    SEC14-like lipid binding 2  Symbol and/or name change 5135510 APPROVED
2015-08-25 Sec14l2  SEC14-like lipid binding 2    SEC14-like 2 (S. cerevisiae)  Symbol and/or name change 5135510 APPROVED