Sord (sorbitol dehydrogenase) - Rat Genome Database

Name: Sord
Creator: Rat Genome Database
License: Creative Commons CC BY 4.0
Keywords: Rat Gene RGD Genome

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Gene: Sord (sorbitol dehydrogenase) Chinchilla lanigera

Analyze

Symbol:

Sord

Name:

sorbitol dehydrogenase

RGD ID:

9036369

Description:

ENCODES a protein that exhibits D-sorbitol dehydrogenase (acceptor) activity (ortholog); D-xylulose reductase activity (ortholog); identical protein binding (ortholog); INVOLVED IN flagellated sperm motility (ortholog); fructose biosynthetic process (ortholog); glucuronate catabolic process to xylulose 5-phosphate (ortholog); PARTICIPATES IN fructose and mannose metabolic pathway; fructosuria pathway; hereditary fructose intolerance syndrome pathway; ASSOCIATED WITH AGAT deficiency (ortholog); Bloom syndrome (ortholog); cataract (ortholog); FOUND IN cytosol (ortholog); extracellular exosome (ortholog); extracellular exosome (ortholog)

Type:

protein-coding

RefSeq Status:

MODEL

Previously known as:

leucine zipper putative tumor suppressor 2-like; LOC102024311

RGD Orthologs

Human

Mouse

Rat

Bonobo

Dog

Squirrel

Pig

Green Monkey

Naked Mole-Rat

Alliance Genes

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	SORD (sorbitol dehydrogenase)	NCBI	Ortholog
Mus musculus (house mouse):	Sord (sorbitol dehydrogenase)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Rattus norvegicus (Norway rat):	Sord (sorbitol dehydrogenase)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	SORD (sorbitol dehydrogenase)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	SORD (sorbitol dehydrogenase)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Sord (sorbitol dehydrogenase)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	SORD (sorbitol dehydrogenase)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	SORD (sorbitol dehydrogenase)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Sord (sorbitol dehydrogenase)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline

Latest Assembly:

ChiLan1.0 - Chinchilla ChiLan1.0 Assembly

Position:

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955409	8,303,602 - 8,333,869 (-)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955409	8,305,819 - 8,333,733 (-)	NCBI	ChiLan1.0	ChiLan1.0

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

AGAT deficiency (ISO)

Bloom syndrome (ISO)

cataract (ISO)

Charcot-Marie-Tooth disease (ISO)

Chemical and Drug Induced Liver Injury (ISO)

colorectal cancer (ISO)

diabetic neuropathy (ISO)

Experimental Diabetes Mellitus (ISO)

genetic disease (ISO)

multiple chemical sensitivity (ISO)

Myocardial Reperfusion Injury (ISO)

neuropathy (ISO)

perinatal necrotizing enterocolitis (ISO)

peripheral nervous system disease (ISO)

Sorbitol Dehydrogenase Deficiency with Peripheral Neuropathy (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

flagellated sperm motility (ISO)

fructose biosynthetic process (ISO)

glucuronate catabolic process to xylulose 5-phosphate (ISO)

L-xylitol catabolic process (ISO)

L-xylitol metabolic process (ISO)

response to cadmium ion (ISO)

response to copper ion (ISO)

response to hormone (ISO)

response to nutrient levels (ISO)

response to osmotic stress (ISO)

response to xenobiotic stimulus (ISO)

sorbitol catabolic process (ISO)

sorbitol metabolic process (ISO)

Cellular Component

cytosol (ISO)

extracellular exosome (ISO)

membrane (ISO)

mitochondrion (ISO)

motile cilium (ISO)

Molecular Function

D-sorbitol dehydrogenase (acceptor) activity (ISO)

D-xylulose reductase activity (ISO)

identical protein binding (ISO)

L-iditol 2-dehydrogenase activity (ISO)

NAD binding (ISO)

zinc ion binding (ISO)

Molecular Pathway Annotations Click to see Annotation Detail View

fructose and mannose metabolic pathway (ISO)

fructosuria pathway (ISO)

hereditary fructose intolerance syndrome pathway (ISO)

References

References - curated

#	Reference Title	Reference Citation
1.	Transitive Annotation Pipeline	Automated assignment of GO, PW and RDO ISO annotations across species

Genomics

Comparative Map Data

Sord
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955409	8,303,602 - 8,333,869 (-)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955409	8,305,819 - 8,333,733 (-)	NCBI	ChiLan1.0	ChiLan1.0

SORD
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	15	45,023,195 - 45,077,185 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p13 Ensembl	15	45,023,147 - 45,077,185 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	15	45,315,393 - 45,369,383 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	15	43,102,633 - 43,154,331 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	15	43,102,643 - 43,154,330	NCBI
Celera	15	22,206,385 - 22,258,718 (+)	NCBI		Celera
Cytogenetic Map	15	q21.1	NCBI
HuRef	15	22,139,528 - 22,191,494 (+)	NCBI		HuRef
CHM1_1	15	45,433,621 - 45,485,599 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	15	42,831,215 - 42,885,202 (+)	NCBI		T2T-CHM13v2.0

Sord
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	2	122,065,320 - 122,095,818 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	2	122,065,230 - 122,095,821 (+)	Ensembl		GRCm39 Ensembl
GRCm38	2	122,234,839 - 122,265,337 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	2	122,234,749 - 122,265,340 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	2	122,060,575 - 122,091,073 (+)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	2	121,926,280 - 121,956,778 (+)	NCBI		MGSCv36	mm8
Celera	2	123,384,583 - 123,415,681 (+)	NCBI		Celera
Cytogenetic Map	2	E5	NCBI
cM Map	2	60.59	NCBI

Sord
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
mRatBN7.2	3	109,184,697 - 109,216,133 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	3	109,184,676 - 109,216,133 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	3	112,858,692 - 112,889,823 (+)	NCBI	Rnor_SHR
UTH_Rnor_SHRSP_BbbUtx_1.0	3	121,454,207 - 121,485,340 (+)	NCBI	Rnor_SHRSP
UTH_Rnor_WKY_Bbb_1.0	3	119,114,585 - 119,145,718 (+)	NCBI	Rnor_WKY
Rnor_6.0	3	114,176,127 - 114,207,368 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	3	114,176,309 - 114,207,366 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	3	120,716,804 - 120,746,951 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	3	109,016,830 - 109,048,446 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	3	108,922,464 - 108,953,299 (+)	NCBI
Celera	3	108,082,883 - 108,113,935 (+)	NCBI		Celera
Cytogenetic Map	3	q35	NCBI

SORD
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
PanPan1.1	15	42,363,854 - 42,375,848 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
Mhudiblu_PPA_v0	15	23,971,017 - 24,025,043 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3

SORD
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	30	11,467,259 - 11,501,166 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	30	11,467,253 - 11,500,641 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	30	11,523,461 - 11,557,483 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	30	11,603,460 - 11,637,883 (+)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	30	11,603,473 - 11,637,887 (+)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	30	11,509,757 - 11,544,158 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	30	11,632,822 - 11,666,883 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	30	11,751,896 - 11,786,120 (+)	NCBI		UU_Cfam_GSD_1.0

Sord
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024408640	89,912,015 - 89,957,526 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936471	7,760,052 - 7,795,671 (+)	Ensembl	SpeTri2.0
SpeTri2.0	NW_004936471	7,760,097 - 7,805,475 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

SORD
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	1	126,655,156 - 126,701,138 (-)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	1	126,659,198 - 126,701,084 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	1	141,259,120 - 141,301,021 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

SORD
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	26	38,129,236 - 38,173,867 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	26	38,126,911 - 38,155,381 (-)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666048	102,884,429 - 102,931,888 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Sord
(Heterocephalus glaber - naked mole-rat)

Naked Mole-rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624731	14,156,522 - 14,185,989 (-)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624731	14,159,439 - 14,185,960 (-)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Expression

Sequence

Nucleotide Sequences


RefSeq Transcripts	XM_005376745	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_013510316	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AGCD01009393	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AGCD01009394	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	GBCQ01010097	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Reference Sequences

RefSeq Acc Id:

ENSCLAT00000013371 ⟹ ENSCLAP00000013220

RefSeq Status:

Type:

CODING

Position:

Chinchilla Assembly	Chr	Position (strand)	Source
ChiLan1.0 Ensembl	NW_004955409	8,303,602 - 8,333,869 (-)	Ensembl

RefSeq Acc Id:

XM_005376745 ⟹ XP_005376802

RefSeq Status:

Type:

CODING

Position:

Chinchilla Assembly	Chr	Position (strand)	Source
ChiLan1.0	NW_004955409	8,305,819 - 8,333,733 (-)	NCBI

Sequence:

show sequence

CTGCCAGCGCGTGGAGGCCCCGCCCCGTCGCGCGCCCGCGAGGCCAGGCTCCGCCTTCCGCCCC
TGACCCCGGACCGCTCGCAGGGCCGGGACCAGAACCACCACCGCGCGTCCCGCCGACTCCGGCC
TCCACCACCCGAGCCCAAGCGACATGGCTGCGCCGGCCAAGGCCGAGAACCTGTCCCTGGTGGT
GCACGGCCCCGGGGACCTTCGCCTGGAGAACTACCCCGTCCCGGAGCCTGGCCCAGACGAGGTG
CTGCTGCGCATGCACTCCGTGGGGATCTGCGGCTCCGACGTCCACTACTGGCAGCACGGCCGGA
TCGGGGACTTCGTCGTGAAGAAGCCGATGGTGCTGGGGCACGAAGCTGCGGGGACGGTGGTGAA
AGTGGGGTCCTCGGTGAAGCACCTGAAAGCAGGTGACCGCGTCGCCATCGAGCCTGGGGCCCCC
CGAGAGACCGATGAATTCTGCAAGGTGGGCCGGTACAACCTGTCCCCAACCATCTTCTTCTGCG
CCACACCCCCGGACGACGGGAACCTCTGTCGCTTCTACAAGCACAACGCCAGCTTCTGCTACAA
GCTCCCCGACGGCGTCACCTTCGAGGAAGGGGCCCTGATCGAGCCTCTGTCCGTGGGGATCCAC
GCCTGCCGGCGCGGCGGAGTCTCCCTGGGAAACAAGGTCTTCGTGTGCGGCGCGGGGCCAGTCG
GGCTGGTCACCTTGATCGTGGCCAAAGCAATGGGCGCAGCGATGGTGGTGGTGAGTGATCTGTC
CGCCTCTCGGCTGTCCAAAGCCAAGGAGGTCGGGGCTGACTTCGTCCTCCAGATCTCCCAGGAG
GGCCCCCAGGAGATCGCCAGCAAGGTGGAAGGGCTGCTGGGGTGCAAGCCGGAAGTCACCATCG
AGTGCACCGGGGCGGAGAGCGCCATCCAGGCGGGCATCTACGCCACCCGCTCTGGGGGGACCCT
GGTTCTGGTGGGCCTGGGTGCCGAGATGATCAACGTGCCCCTGGTGCACGCCGCCGTCCGGGAG
GTGGACATCAAGGGCGTGTTCCGGTACTGCAACACGTGGCCCATGGCCATTTCCATGCTTGCAG
CCAAGGCCGTGAACGTAAAGCCCTTAGTCACCCATCGGTTTCCTCTGGAGAAAGCTCTGGAGGC
CTTCGAAACATCCAAAAAGGGGGTGGGGGTGAAGGTCATGCTCAAGTGTGACCCCAACGACCAG
AACCCCTGAGGCGACCTGGGCCGTCACCCCCCCCCCGGCCTCTCTGCGTCGCGGGGCCCAGCGG
TCGGCCAATCTGTGCTCGGAGCCGTCAGGATGATAATGTAGGGCTGGGCAGTGGTTCAGGCCGG
GTGCTTGCCTAGCACGCATGAAGCTCAGGGGTTAATCCCCAGTCCTACCAAAAAATAAAAAAAA
AATGAAAAATGAGAAAAAATGTAAATCATGAATGTAATTCATTGCCAACAGAGAGCCTTCCAGA
GGGGTAGGTGTGCCTTAACGTCACAAGCAGAGGCAGTTCTGGGGGGACTGGGCACCAGCACTAC
CCCGCTCTTGAGGAGCCAAGGTGGCTGTGGGGTGCCGGGTCCCCTCTTCAGATCCGGCCCTCAG
GTTCCTGGCTCCGCTGTGATGGGCTGAGTACTGCAGAAAGATCATCGCGGAGTCCCACCTGGCC
TTGGTCGGTCACTGGCAGGGTGTGGGCGGCGGTGGTCAGCAGTCGTCGTCACAGTACGGGGCTC
TGGAGGAGGAGAAGAAAGAGGGGACCAACTTCCTGGGCCCAGGATGACGTCGAGGTCAATCAAG
GATTAAAACCTAGCGAGCCTGCAGTGCTGTGGTGCAGAAAGAGCTAGGGCCCTTCTCAGACAGC
TTGGAGACAGGCTCTTCCACCCCTCGGAGCCCCTCCCAGCATCCCAGCCCCACCAGGGTCCCTG
TTGCTAGGCAACCGGAGGACTTCCGCCTGCGGGCAGTGGCTGGCAGACCTGAGCGTTTTGGCTC
TGCCCGCCCCACGGTCCGAATCCCCACACGGCTCACTCAGGGACCATTGTCAGGCAGTTCAGCC
GCGTCCTGTCATTGGAGACAGTAAACTCTCCCCTCCTCTTAGTCACAGGGCACTGTGTACCTAT
AATCTCCACCACTGGGCCGCACCCCCAGCTAAGCCTATAATCTCATCAACTCAGGAGACTGAGG
CAGGCTGTTTGCAAGTTCAAGGGCAAGCTGGGCACATTTAGTAACACTCTATCCCAGAATAAAA
AGGACAGGAATCTAGCTGAGTTGTACAAGGTCCTGGGGTGTTTTGTTTTGTTTGTTTGTGTTCG
AGGTAGGGTCTCTTTATGTAATCGCATGCACTGTGTAACCCAGGCTGGCCTTGAACTTGTGCTG
ATCCTCCTGCCTCAGCCTCAGGAGTACTGAGATTATAGGCGCACTGACCACACCCACCTGTGTC
CCAGGTTCTTGCAAAGAGCAAAAGAAAAGGCTCTTGGTACTTTGCTGTCTGCAGGAAAAGACAT
CTCTGACCGTGTCTTCTACTCATGACGAGGTTTCTCTGTGTAAGACTGGGATCCAGATCATAAT
GTACGCTTGGCGATTCAGAGATGCTTAATGGAGAGTGAGGGTACAGCGGCTGTCAGCCTCTCGC
TGGAGCTGCGGGTGGGGGTGTGTGGGAAGGGATGTGGGTTTTCTTGTACCCTCTGCAGGCCTAG
CCGGTGCACAGAACTCCTCCACCTCCAGCTGCCCCGGTCACGAATCCCATCAAATCTGCCTGTC
TAAGAAGCGGTGCCCTCAGCCTGCTGCGTTCTCAGAGGAAAGAATCCCAGGACTTCTGCTGGGG
ACTCCCGCGCTGTGGGAGCCAGAATCGCACTGACTGCTGGAAGTACTGTTTGTGTCCACTGTAA
CCCCCACAGCAAGCCAGTTACCTGGCAGTTACTTTGCAGATGATGAAGCAGGGAAATAAAGTGG
TTCTGCCAAG

hide sequence

RefSeq Acc Id:

XM_013510316 ⟹ XP_013365770

RefSeq Status:

Type:

CODING

Position:

Chinchilla Assembly	Chr	Position (strand)	Source
ChiLan1.0	NW_004955409	8,305,819 - 8,329,546 (-)	NCBI

Sequence:

show sequence

AGTGGGCGCAAAGCTTAGCAGTCTGCTGCTCCCTGGGGGCGAAAGCAGCGTGGCCGACTCCTGC
GGGAAGAGCTGGGGCTAGCAAACAGCCCAGAGAGATCCCTGCCTTCTCGTGATGAGAACTACCC
CGTCCCGGAGCCTGGCCCAGACGAGGTGCTGCTGCGCATGCACTCCGTGGGGATCTGCGGCTCC
GACGTCCACTACTGGCAGCACGGCCGGATCGGGGACTTCGTCGTGAAGAAGCCGATGGTGCTGG
GGCACGAAGCTGCGGGGACGGTGGTGAAAGTGGGGTCCTCGGTGAAGCACCTGAAAGCAGGTGA
CCGCGTCGCCATCGAGCCTGGGGCCCCCCGAGAGACCGATGAATTCTGCAAGGTGGGCCGGTAC
AACCTGTCCCCAACCATCTTCTTCTGCGCCACACCCCCGGACGACGGGAACCTCTGTCGCTTCT
ACAAGCACAACGCCAGCTTCTGCTACAAGCTCCCCGACGGCGTCACCTTCGAGGAAGGGGCCCT
GATCGAGCCTCTGTCCGTGGGGATCCACGCCTGCCGGCGCGGCGGAGTCTCCCTGGGAAACAAG
GTCTTCGTGTGCGGCGCGGGGCCAGTCGGGCTGGTCACCTTGATCGTGGCCAAAGCAATGGGCG
CAGCGATGGTGGTGGTGAGTGATCTGTCCGCCTCTCGGCTGTCCAAAGCCAAGGAGGTCGGGGC
TGACTTCGTCCTCCAGATCTCCCAGGAGGGCCCCCAGGAGATCGCCAGCAAGGTGGAAGGGCTG
CTGGGGTGCAAGCCGGAAGTCACCATCGAGTGCACCGGGGCGGAGAGCGCCATCCAGGCGGGCA
TCTACGCCACCCGCTCTGGGGGGACCCTGGTTCTGGTGGGCCTGGGTGCCGAGATGATCAACGT
GCCCCTGGTGCACGCCGCCGTCCGGGAGGTGGACATCAAGGGCGTGTTCCGGTACTGCAACACG
TGGCCCATGGCCATTTCCATGCTTGCAGCCAAGGCCGTGAACGTAAAGCCCTTAGTCACCCATC
GGTTTCCTCTGGAGAAAGCTCTGGAGGCCTTCGAAACATCCAAAAAGGGGGTGGGGGTGAAGGT
CATGCTCAAGTGTGACCCCAACGACCAGAACCCCTGAGGCGACCTGGGCCGTCACCCCCCCCCC
GGCCTCTCTGCGTCGCGGGGCCCAGCGGTCGGCCAATCTGTGCTCGGAGCCGTCAGGATGATAA
TGTAGGGCTGGGCAGTGGTTCAGGCCGGGTGCTTGCCTAGCACGCATGAAGCTCAGGGGTTAAT
CCCCAGTCCTACCAAAAAATAAAAAAAAAATGAAAAATGAGAAAAAATGTAAATCATGAATGTA
ATTCATTGCCAACAGAGAGCCTTCCAGAGGGGTAGGTGTGCCTTAACGTCACAAGCAGAGGCAG
TTCTGGGGGGACTGGGCACCAGCACTACCCCGCTCTTGAGGAGCCAAGGTGGCTGTGGGGTGCC
GGGTCCCCTCTTCAGATCCGGCCCTCAGGTTCCTGGCTCCGCTGTGATGGGCTGAGTACTGCAG
AAAGATCATCGCGGAGTCCCACCTGGCCTTGGTCGGTCACTGGCAGGGTGTGGGCGGCGGTGGT
CAGCAGTCGTCGTCACAGTACGGGGCTCTGGAGGAGGAGAAGAAAGAGGGGACCAACTTCCTGG
GCCCAGGATGACGTCGAGGTCAATCAAGGATTAAAACCTAGCGAGCCTGCAGTGCTGTGGTGCA
GAAAGAGCTAGGGCCCTTCTCAGACAGCTTGGAGACAGGCTCTTCCACCCCTCGGAGCCCCTCC
CAGCATCCCAGCCCCACCAGGGTCCCTGTTGCTAGGCAACCGGAGGACTTCCGCCTGCGGGCAG
TGGCTGGCAGACCTGAGCGTTTTGGCTCTGCCCGCCCCACGGTCCGAATCCCCACACGGCTCAC
TCAGGGACCATTGTCAGGCAGTTCAGCCGCGTCCTGTCATTGGAGACAGTAAACTCTCCCCTCC
TCTTAGTCACAGGGCACTGTGTACCTATAATCTCCACCACTGGGCCGCACCCCCAGCTAAGCCT
ATAATCTCATCAACTCAGGAGACTGAGGCAGGCTGTTTGCAAGTTCAAGGGCAAGCTGGGCACA
TTTAGTAACACTCTATCCCAGAATAAAAAGGACAGGAATCTAGCTGAGTTGTACAAGGTCCTGG
GGTGTTTTGTTTTGTTTGTTTGTGTTCGAGGTAGGGTCTCTTTATGTAATCGCATGCACTGTGT
AACCCAGGCTGGCCTTGAACTTGTGCTGATCCTCCTGCCTCAGCCTCAGGAGTACTGAGATTAT
AGGCGCACTGACCACACCCACCTGTGTCCCAGGTTCTTGCAAAGAGCAAAAGAAAAGGCTCTTG
GTACTTTGCTGTCTGCAGGAAAAGACATCTCTGACCGTGTCTTCTACTCATGACGAGGTTTCTC
TGTGTAAGACTGGGATCCAGATCATAATGTACGCTTGGCGATTCAGAGATGCTTAATGGAGAGT
GAGGGTACAGCGGCTGTCAGCCTCTCGCTGGAGCTGCGGGTGGGGGTGTGTGGGAAGGGATGTG
GGTTTTCTTGTACCCTCTGCAGGCCTAGCCGGTGCACAGAACTCCTCCACCTCCAGCTGCCCCG
GTCACGAATCCCATCAAATCTGCCTGTCTAAGAAGCGGTGCCCTCAGCCTGCTGCGTTCTCAGA
GGAAAGAATCCCAGGACTTCTGCTGGGGACTCCCGCGCTGTGGGAGCCAGAATCGCACTGACTG
CTGGAAGTACTGTTTGTGTCCACTGTAACCCCCACAGCAAGCCAGTTACCTGGCAGTTACTTTG
CAGATGATGAAGCAGGGAAATAAAGTGGTTCTGCCAAG

hide sequence

Protein Sequences


Protein RefSeqs	XP_005376802	(Get FASTA)	NCBI Sequence Viewer
	XP_013365770	(Get FASTA)	NCBI Sequence Viewer

Reference Sequences

RefSeq Acc Id:	XP_005376802 ⟸ XM_005376745
- Peptide Label:	isoform X1
- UniProtKB:	A0A8C2VDZ7 (UniProtKB/TrEMBL)
- Sequence:	show sequence MAAPAKAENLSLVVHGPGDLRLENYPVPEPGPDEVLLRMHSVGICGSDVHYWQHGRIGDFVVKK PMVLGHEAAGTVVKVGSSVKHLKAGDRVAIEPGAPRETDEFCKVGRYNLSPTIFFCATPPDDGN LCRFYKHNASFCYKLPDGVTFEEGALIEPLSVGIHACRRGGVSLGNKVFVCGAGPVGLVTLIVA KAMGAAMVVVSDLSASRLSKAKEVGADFVLQISQEGPQEIASKVEGLLGCKPEVTIECTGAESA IQAGIYATRSGGTLVLVGLGAEMINVPLVHAAVREVDIKGVFRYCNTWPMAISMLAAKAVNVKP LVTHRFPLEKALEAFETSKKGVGVKVMLKCDPNDQNP hide sequence

RefSeq Acc Id:

XP_013365770 ⟸ XM_013510316

- Peptide Label:

isoform X2

- Sequence:

show sequence

MHSVGICGSDVHYWQHGRIGDFVVKKPMVLGHEAAGTVVKVGSSVKHLKAGDRVAIEPGAPRET
DEFCKVGRYNLSPTIFFCATPPDDGNLCRFYKHNASFCYKLPDGVTFEEGALIEPLSVGIHACR
RGGVSLGNKVFVCGAGPVGLVTLIVAKAMGAAMVVVSDLSASRLSKAKEVGADFVLQISQEGPQ
EIASKVEGLLGCKPEVTIECTGAESAIQAGIYATRSGGTLVLVGLGAEMINVPLVHAAVREVDI
KGVFRYCNTWPMAISMLAAKAVNVKPLVTHRFPLEKALEAFETSKKGVGVKVMLKCDPNDQNP

hide sequence

RefSeq Acc Id:

ENSCLAP00000013220 ⟸ ENSCLAT00000013371

Protein Domains

Enoyl reductase (ER)

Additional Information

External Database Links

Database	Acc Id	Source(s)
Ensembl Genes	ENSCLAG00000009127	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein	ENSCLAP00000013220	ENTREZGENE
	ENSCLAP00000013220.1	UniProtKB/TrEMBL
Ensembl Transcript	ENSCLAT00000013371	ENTREZGENE
	ENSCLAT00000013371.1	UniProtKB/TrEMBL
Gene3D-CATH	Medium-chain alcohol dehydrogenases, catalytic domain	UniProtKB/TrEMBL
	NAD(P)-binding Rossmann-like Domain	UniProtKB/TrEMBL
InterPro	ADH-like_C	UniProtKB/TrEMBL
	ADH_N	UniProtKB/TrEMBL
	ADH_Zn_CS	UniProtKB/TrEMBL
	GroES-like_sf	UniProtKB/TrEMBL
	NAD(P)-bd_dom_sf	UniProtKB/TrEMBL
	PKS_ER	UniProtKB/TrEMBL
	SDH-like	UniProtKB/TrEMBL
NCBI Gene	Sord	ENTREZGENE
PANTHER	SORBITOL DEHYDROGENASE	UniProtKB/TrEMBL
	SORBITOL DEHYDROGENASE	UniProtKB/TrEMBL
Pfam	ADH_N	UniProtKB/TrEMBL
	ADH_zinc_N	UniProtKB/TrEMBL
PROSITE	ADH_ZINC	UniProtKB/TrEMBL
SMART	PKS_ER	UniProtKB/TrEMBL
Superfamily-SCOP	SSF50129	UniProtKB/TrEMBL
	SSF51735	UniProtKB/TrEMBL
UniProt	A0A8C2VDZ7	ENTREZGENE, UniProtKB/TrEMBL

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2017-11-21	Sord	sorbitol dehydrogenase	LOC102024311	leucine zipper putative tumor suppressor 2-like	Data Merged	737654	PROVISIONAL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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Imported Disease Annotations - CTD

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Imported Disease Annotations - OMIM

Imported Annotations - SMPDB

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