Prkcd (protein kinase C delta) - Rat Genome Database

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Gene: Prkcd (protein kinase C delta) Chinchilla lanigera
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Symbol: Prkcd
Name: protein kinase C delta
RGD ID: 9033515
Description: ENCODES a protein that exhibits calcium-independent protein kinase C activity (ortholog); enzyme activator activity (ortholog); enzyme binding (ortholog); INVOLVED IN activation of protein kinase activity (ortholog); aging (ortholog); apoptotic process (ortholog); PARTICIPATES IN ceramide signaling pathway; eicosanoid signaling pathway; endothelin signaling pathway; ASSOCIATED WITH autoimmune lymphoproliferative syndrome type 3 (ortholog); brain ischemia (ortholog); Burns (ortholog); FOUND IN cell-cell junction (ortholog); cytoplasm (ortholog); cytosol (ortholog)
Type: protein-coding
RefSeq Status: MODEL
RGD Orthologs
Human
Mouse
Rat
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: ChiLan1.0 - Chinchilla ChiLan1.0 Assembly
Position:
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554303,124,738 - 3,153,274 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554303,125,066 - 3,151,857 (+)NCBIChiLan1.0ChiLan1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process
activation of protein kinase activity  (ISO)
aging  (ISO)
apoptotic process  (ISO)
B cell proliferation  (ISO)
cell chemotaxis  (ISO)
cellular response to angiotensin  (ISO)
cellular response to glucose starvation  (ISO)
cellular response to hydrogen peroxide  (ISO)
cellular response to hydroperoxide  (ISO)
cellular response to insulin stimulus  (ISO)
cellular response to oxidative stress  (ISO)
cellular response to UV  (ISO)
cellular senescence  (ISO)
collagen metabolic process  (ISO)
D-aspartate import across plasma membrane  (ISO)
defense response to bacterium  (ISO)
histone phosphorylation  (ISO)
immunoglobulin mediated immune response  (ISO)
intracellular signal transduction  (ISO)
negative regulation of actin filament polymerization  (ISO)
negative regulation of filopodium assembly  (ISO)
negative regulation of glial cell apoptotic process  (ISO)
negative regulation of insulin receptor signaling pathway  (ISO)
negative regulation of MAP kinase activity  (ISO)
negative regulation of peptidyl-tyrosine phosphorylation  (ISO)
negative regulation of platelet aggregation  (ISO)
neutrophil activation  (ISO)
peptidyl-serine phosphorylation  (ISO)
peptidyl-threonine phosphorylation  (ISO)
positive regulation of apoptotic process  (ISO)
positive regulation of apoptotic signaling pathway  (ISO)
positive regulation of ceramide biosynthetic process  (ISO)
positive regulation of endodeoxyribonuclease activity  (ISO)
positive regulation of glucose import  (ISO)
positive regulation of glucosylceramide catabolic process  (ISO)
positive regulation of MAP kinase activity  (ISO)
positive regulation of MAPK cascade  (ISO)
positive regulation of phospholipid scramblase activity  (ISO)
positive regulation of protein dephosphorylation  (ISO)
positive regulation of protein import into nucleus  (ISO)
positive regulation of response to DNA damage stimulus  (ISO)
positive regulation of sphingomyelin catabolic process  (ISO)
positive regulation of superoxide anion generation  (ISO)
protein autophosphorylation  (ISO)
protein phosphorylation  (ISO)
regulation of actin cytoskeleton organization  (ISO)
regulation of ceramide biosynthetic process  (ISO)
regulation of phosphorylation  (ISO)
response to amino acid  (ISO)
response to ethanol  (ISO)
response to glucose  (ISO)
response to heat  (ISO)
response to hydrogen peroxide  (ISO)
response to hypoxia  (ISO)
response to mechanical stimulus  (ISO)
response to organic cyclic compound  (ISO)
response to organonitrogen compound  (ISO)
response to oxidative stress  (ISO)
response to xenobiotic stimulus  (ISO)
termination of signal transduction  (ISO)

Cellular Component

References


Genomics

Comparative Map Data
Prkcd
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554303,124,738 - 3,153,274 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554303,125,066 - 3,151,857 (+)NCBIChiLan1.0ChiLan1.0
PRKCD
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl353,156,009 - 53,192,717 (+)EnsemblGRCh38hg38GRCh38
GRCh38353,161,209 - 53,192,717 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh37353,195,225 - 53,226,733 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36353,170,263 - 53,201,773 (+)NCBINCBI36hg18NCBI36
Build 34353,170,262 - 53,201,771NCBI
Celera353,162,239 - 53,193,756 (+)NCBI
Cytogenetic Map3p21.1NCBI
HuRef353,210,511 - 53,276,026 (+)NCBIHuRef
CHM1_1353,146,796 - 53,178,291 (+)NCBICHM1_1
Prkcd
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391430,317,310 - 30,348,637 (-)NCBIGRCm39mm39
GRCm39 Ensembl1430,317,311 - 30,348,167 (-)Ensembl
GRCm381430,595,353 - 30,626,414 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1430,595,354 - 30,626,210 (-)EnsemblGRCm38mm10GRCm38
MGSCv371431,408,555 - 31,423,498 (-)NCBIGRCm37mm9NCBIm37
MGSCv361429,424,378 - 29,447,560 (-)NCBImm8
Celera1426,853,019 - 26,867,962 (-)NCBICelera
Cytogenetic Map14BNCBI
cM Map1418.82NCBI
Prkcd
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2165,769,226 - 5,807,214 (-)NCBI
Rnor_6.0 Ensembl166,655,120 - 6,675,746 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.0166,655,131 - 6,675,746 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0166,588,990 - 6,608,725 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4165,954,218 - 5,975,743 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1165,954,214 - 5,975,741 (-)NCBI
Celera169,398,816 - 9,419,806 (+)NCBICelera
Cytogenetic Map16p16NCBI
PRKCD
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.1354,330,328 - 54,357,910 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl354,330,328 - 54,357,910 (+)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v0353,104,137 - 53,135,588 (+)NCBIMhudiblu_PPA_v0panPan3
PRKCD
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12036,723,491 - 36,751,982 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2036,723,809 - 36,752,191 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2036,660,459 - 36,673,894 (-)NCBI
ROS_Cfam_1.02037,001,697 - 37,030,998 (-)NCBI
UMICH_Zoey_3.12036,438,983 - 36,452,419 (-)NCBI
UNSW_CanFamBas_1.02036,800,686 - 36,814,133 (-)NCBI
UU_Cfam_GSD_1.02037,015,742 - 37,029,186 (-)NCBI
Prkcd
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405118170,754,028 - 170,788,044 (+)NCBI
SpeTri2.0NW_0049364733,892,625 - 3,923,467 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
PRKCD
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1335,290,264 - 35,323,356 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11335,290,835 - 35,323,245 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21338,361,707 - 38,390,508 (+)NCBISscrofa10.2Sscrofa10.2susScr3
PRKCD
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12214,561,401 - 14,592,877 (+)NCBI
ChlSab1.1 Ensembl2214,565,282 - 14,592,873 (+)Ensembl
Vero_WHO_p1.0NW_023666041152,302,998 - 152,334,406 (-)NCBI
Prkcd
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046248224,035,819 - 4,062,907 (-)NCBI


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSCLAT00000005849   ⟹   ENSCLAP00000005748
RefSeq Status:
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_0049554303,124,738 - 3,153,274 (+)Ensembl
RefSeq Acc Id: ENSCLAT00000005850   ⟹   ENSCLAP00000005749
RefSeq Status:
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_0049554303,125,066 - 3,153,274 (+)Ensembl
RefSeq Acc Id: ENSCLAT00000005851   ⟹   ENSCLAP00000005750
RefSeq Status:
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_0049554303,139,148 - 3,151,567 (+)Ensembl
RefSeq Acc Id: XM_005387365   ⟹   XP_005387422
RefSeq Status:
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_0049554303,125,066 - 3,151,857 (+)NCBI
Sequence:
RefSeq Acc Id: XM_013515681   ⟹   XP_013371135
RefSeq Status:
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_0049554303,125,066 - 3,151,857 (+)NCBI
Sequence:
RefSeq Acc Id: XM_013515682   ⟹   XP_013371136
RefSeq Status:
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_0049554303,125,066 - 3,151,857 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_005387422 (Get FASTA)   NCBI Sequence Viewer  
  XP_013371135 (Get FASTA)   NCBI Sequence Viewer  
  XP_013371136 (Get FASTA)   NCBI Sequence Viewer  
Reference Sequences
RefSeq Acc Id: XP_005387422   ⟸   XM_005387365
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: XP_013371135   ⟸   XM_013515681
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_013371136   ⟸   XM_013515682
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: ENSCLAP00000005748   ⟸   ENSCLAT00000005849
RefSeq Acc Id: ENSCLAP00000005750   ⟸   ENSCLAT00000005851
RefSeq Acc Id: ENSCLAP00000005749   ⟸   ENSCLAT00000005850


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCLAG00000004074 Ensembl, ENTREZGENE
Ensembl Protein ENSCLAP00000005749 ENTREZGENE
  ENSCLAP00000005750 ENTREZGENE
Ensembl Transcript ENSCLAT00000005850 ENTREZGENE
  ENSCLAT00000005851 ENTREZGENE
NCBI Gene Prkcd ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-08-03 Prkcd  protein kinase C delta    protein kinase C, delta  Symbol and/or name change 5135510 APPROVED