Hsd17b2 (hydroxysteroid 17-beta dehydrogenase 2) - Rat Genome Database

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Gene: Hsd17b2 (hydroxysteroid 17-beta dehydrogenase 2) Chinchilla lanigera
Analyze
Symbol: Hsd17b2
Name: hydroxysteroid 17-beta dehydrogenase 2
RGD ID: 9033454
Description: ENCODES a protein that exhibits estradiol 17-beta-dehydrogenase [NAD(P)] activity (ortholog); testosterone dehydrogenase (NAD+) activity (ortholog); INVOLVED IN androgen biosynthetic process (ortholog); androgen metabolic process (ortholog); bone development (ortholog); PARTICIPATES IN estradiol biosynthetic pathway; testosterone biosynthetic pathway; ASSOCIATED WITH Endometrial Neoplasms (ortholog); endometriosis (ortholog); Experimental Liver Cirrhosis (ortholog); FOUND IN endoplasmic reticulum membrane (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: estradiol 17-beta-dehydrogenase 2; hydroxysteroid (17-beta) dehydrogenase 2
RGD Orthologs
Human
Mouse
Rat
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: ChiLan1.0 - Chinchilla ChiLan1.0 Assembly
Position:
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555641,922,703 - 1,983,966 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049555641,884,235 - 1,984,182 (-)NCBIChiLan1.0ChiLan1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Transitive Annotation Pipeline Automated assignment of GO, PW and RDO ISO annotations across species

Genomics

Comparative Map Data
Hsd17b2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555641,922,703 - 1,983,966 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049555641,884,235 - 1,984,182 (-)NCBIChiLan1.0ChiLan1.0
HSD17B2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381682,035,253 - 82,098,534 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1682,035,004 - 82,098,534 (+)EnsemblGRCh38hg38GRCh38
GRCh371682,068,858 - 82,132,139 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361680,626,364 - 80,689,638 (+)NCBINCBI36Build 36hg18NCBI36
Build 341680,626,363 - 80,689,638NCBI
Celera1666,367,527 - 66,430,804 (+)NCBICelera
Cytogenetic Map16q23.3NCBI
HuRef1667,822,411 - 67,885,688 (+)NCBIHuRef
CHM1_11683,480,225 - 83,543,515 (+)NCBICHM1_1
T2T-CHM13v2.01688,098,974 - 88,162,234 (+)NCBIT2T-CHM13v2.0
Hsd17b2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm398118,427,752 - 118,485,767 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl8118,428,643 - 118,485,766 (+)EnsemblGRCm39 Ensembl
GRCm388117,700,982 - 117,759,030 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl8117,701,904 - 117,759,027 (+)EnsemblGRCm38mm10GRCm38
MGSCv378120,225,846 - 120,282,929 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv368120,587,962 - 120,644,851 (+)NCBIMGSCv36mm8
Celera8121,922,376 - 121,979,885 (+)NCBICelera
Cytogenetic Map8E1NCBI
cM Map864.82NCBI
Hsd17b2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81962,662,320 - 62,733,944 (+)NCBIGRCr8
mRatBN7.21945,753,576 - 45,825,203 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1945,753,574 - 45,825,202 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1952,565,001 - 52,636,759 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01953,216,191 - 53,287,955 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01955,460,429 - 55,532,204 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01950,246,404 - 50,317,892 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1950,246,402 - 50,317,891 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01961,033,236 - 61,101,461 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41947,729,519 - 47,802,933 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11947,734,400 - 47,807,814 (-)NCBI
Celera1945,023,173 - 45,093,239 (+)NCBICelera
Cytogenetic Map19q12NCBI
HSD17B2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21891,785,636 - 91,848,535 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11697,705,141 - 97,768,166 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01662,642,316 - 62,705,261 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11682,062,047 - 82,125,039 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1682,062,042 - 82,125,139 (+)Ensemblpanpan1.1panPan2
HSD17B2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1569,927,888 - 70,009,306 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl569,927,984 - 70,009,179 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha569,936,380 - 70,023,461 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0570,226,818 - 70,314,083 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl570,232,641 - 70,314,177 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1570,169,271 - 70,257,042 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0570,005,963 - 70,093,190 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0570,423,292 - 70,510,487 (-)NCBIUU_Cfam_GSD_1.0
Hsd17b2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440934930,094,893 - 30,162,355 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493647529,426,883 - 29,494,225 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493647529,426,922 - 29,494,215 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
HSD17B2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl66,292,707 - 6,360,633 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.166,296,429 - 6,360,434 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.266,885,015 - 6,885,284 (-)NCBISscrofa10.2Sscrofa10.2susScr3
HSD17B2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1567,464,986 - 67,529,079 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl567,464,334 - 67,529,182 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660478,304,938 - 8,368,998 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Hsd17b2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247465,368,142 - 5,446,429 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247465,372,176 - 5,445,726 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSCLAT00000001600   ⟹   ENSCLAP00000001557
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_0049555641,922,703 - 1,983,966 (-)Ensembl
RefSeq Acc Id: XM_005413241   ⟹   XP_005413298
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_0049555641,923,456 - 1,984,172 (-)NCBI
Sequence:
RefSeq Acc Id: XM_005413242   ⟹   XP_005413299
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_0049555641,884,235 - 1,984,182 (-)NCBI
Sequence:
RefSeq Acc Id: XM_013509198   ⟹   XP_013364652
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_0049555641,923,456 - 1,984,179 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_005413298 (Get FASTA)   NCBI Sequence Viewer  
  XP_005413299 (Get FASTA)   NCBI Sequence Viewer  
  XP_013364652 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSCLAP00000001557
  ENSCLAP00000001557.1
Reference Protein Sequences
RefSeq Acc Id: XP_005413299   ⟸   XM_005413242
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: XP_005413298   ⟸   XM_005413241
- Peptide Label: isoform X1
- UniProtKB: A0A8C2YIP4 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_013364652   ⟸   XM_013509198
- Peptide Label: isoform X3
- Sequence:
RefSeq Acc Id: ENSCLAP00000001557   ⟸   ENSCLAT00000001600


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCLAG00000001169 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCLAT00000001600 ENTREZGENE
  ENSCLAT00000001600.1 UniProtKB/TrEMBL
Gene3D-CATH NAD(P)-binding Rossmann-like Domain UniProtKB/TrEMBL
InterPro NAD(P)-bd_dom_sf UniProtKB/TrEMBL
  SDR_fam UniProtKB/TrEMBL
NCBI Gene Hsd17b2 ENTREZGENE
PANTHER 17-BETA-HYDROXYSTEROID DEHYDROGENASE TYPE 2 UniProtKB/TrEMBL
  SHORT-CHAIN DEHYDROGENASE/REDUCTASE FAMILY 9C UniProtKB/TrEMBL
Pfam adh_short UniProtKB/TrEMBL
PRINTS GDHRDH UniProtKB/TrEMBL
  SDRFAMILY UniProtKB/TrEMBL
Superfamily-SCOP SSF51735 UniProtKB/TrEMBL
UniProt A0A8C2YIP4 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-08-03 Hsd17b2  hydroxysteroid 17-beta dehydrogenase 2    hydroxysteroid (17-beta) dehydrogenase 2  Symbol and/or name change 5135510 APPROVED