Ltbp4 (latent transforming growth factor beta binding protein 4) - Rat Genome Database

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Gene: Ltbp4 (latent transforming growth factor beta binding protein 4) Chinchilla lanigera
Analyze
Symbol: Ltbp4
Name: latent transforming growth factor beta binding protein 4
RGD ID: 9033008
Description: ENCODES a protein that exhibits transforming growth factor beta binding (ortholog); INVOLVED IN elastic fiber assembly (ortholog); hormone secretion (ortholog); transforming growth factor beta receptor signaling pathway (ortholog); ASSOCIATED WITH autosomal recessive cutis laxa type IC (ortholog); Carpenter Syndrome 2 (ortholog); congenital hypoplastic anemia (ortholog); FOUND IN collagen-containing extracellular matrix (ortholog); extracellular matrix (ortholog); microfibril (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: latent-transforming growth factor beta-binding protein 4
RGD Orthologs
Human
Mouse
Rat
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: ChiLan1.0 - Chinchilla ChiLan1.0 Assembly
Position:
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955578686,211 - 712,794 (-)EnsemblChiLan1.0
ChiLan1.0NW_004955578685,960 - 712,809 (-)NCBIChiLan1.0ChiLan1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Transitive Annotation Pipeline Automated assignment of GO, PW and RDO ISO annotations across species
2. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
Additional References at PubMed
PMID:22301074  


Genomics

Comparative Map Data
Ltbp4
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955578686,211 - 712,794 (-)EnsemblChiLan1.0
ChiLan1.0NW_004955578685,960 - 712,809 (-)NCBIChiLan1.0ChiLan1.0
LTBP4
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381940,593,166 - 40,629,820 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1940,592,883 - 40,629,818 (+)EnsemblGRCh38hg38GRCh38
GRCh371941,099,072 - 41,135,725 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361945,790,912 - 45,827,565 (+)NCBINCBI36Build 36hg18NCBI36
Build 341945,790,911 - 45,827,562NCBI
Celera1937,898,123 - 37,934,766 (+)NCBICelera
Cytogenetic Map19q13.2NCBI
HuRef1937,533,157 - 37,570,214 (+)NCBIHuRef
CHM1_11941,098,957 - 41,135,597 (+)NCBICHM1_1
T2T-CHM13v2.01943,413,757 - 43,450,378 (+)NCBIT2T-CHM13v2.0
Ltbp4
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39727,004,566 - 27,039,142 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl727,004,561 - 27,037,117 (-)EnsemblGRCm39 Ensembl
GRCm38727,305,140 - 27,339,720 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl727,305,136 - 27,337,692 (-)EnsemblGRCm38mm10GRCm38
MGSCv37728,090,160 - 28,122,631 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36727,013,902 - 27,046,452 (-)NCBIMGSCv36mm8
Celera721,881,870 - 21,917,412 (-)NCBICelera
Cytogenetic Map7A3NCBI
cM Map715.87NCBI
Ltbp4
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8191,727,769 - 91,759,822 (-)NCBIGRCr8
mRatBN7.2182,600,136 - 82,634,346 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl182,600,136 - 82,632,178 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx188,002,794 - 88,034,858 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0196,489,706 - 96,521,689 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0189,758,660 - 89,790,713 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0184,118,046 - 84,152,095 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl184,118,046 - 84,150,084 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0185,328,915 - 85,361,198 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4182,385,953 - 82,418,177 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1182,464,068 - 82,487,843 (-)NCBI
Celera177,011,604 - 77,043,761 (-)NCBICelera
Cytogenetic Map1q21NCBI
LTBP4
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22046,851,772 - 46,889,066 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11948,722,675 - 48,759,989 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01937,637,509 - 37,674,791 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11946,144,485 - 46,181,636 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1946,144,485 - 46,181,636 (+)Ensemblpanpan1.1panPan2
LTBP4
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11113,124,109 - 113,152,283 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1113,124,109 - 113,150,442 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1112,526,364 - 112,552,684 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01113,722,679 - 113,749,021 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1113,722,688 - 113,749,021 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11113,282,295 - 113,308,625 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01112,913,954 - 112,940,503 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01113,908,479 - 113,934,829 (-)NCBIUU_Cfam_GSD_1.0
Ltbp4
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440934914,489,689 - 14,517,783 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366612,919,550 - 2,945,599 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049366612,919,444 - 2,945,847 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
LTBP4
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl648,831,014 - 48,861,507 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1648,831,018 - 48,861,503 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2644,591,804 - 44,609,182 (+)NCBISscrofa10.2Sscrofa10.2susScr3
LTBP4
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1635,056,287 - 35,090,544 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl635,061,225 - 35,090,542 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366607313,179,976 - 13,213,847 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Ltbp4
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_004624925545,438 - 573,428 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_004624925543,656 - 572,810 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSCLAT00000001038   ⟹   ENSCLAP00000001000
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_004955578686,211 - 712,794 (-)Ensembl
RefSeq Acc Id: ENSCLAT00000001039   ⟹   ENSCLAP00000001001
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_004955578686,211 - 712,794 (-)Ensembl
RefSeq Acc Id: ENSCLAT00000001040   ⟹   ENSCLAP00000001002
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_004955578686,211 - 708,066 (-)Ensembl
RefSeq Acc Id: ENSCLAT00000001041   ⟹   ENSCLAP00000001003
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_004955578688,244 - 692,078 (-)Ensembl
RefSeq Acc Id: XM_005414039   ⟹   XP_005414096
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_004955578685,960 - 712,809 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_005414096 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSCLAP00000001000
  ENSCLAP00000001000.1
  ENSCLAP00000001001.1
  ENSCLAP00000001002.1
  ENSCLAP00000001003.1
Reference Protein Sequences
RefSeq Acc Id: XP_005414096   ⟸   XM_005414039
- UniProtKB: A0A8C2UKC0 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSCLAP00000001002   ⟸   ENSCLAT00000001040
RefSeq Acc Id: ENSCLAP00000001003   ⟸   ENSCLAT00000001041
RefSeq Acc Id: ENSCLAP00000001001   ⟸   ENSCLAT00000001039
RefSeq Acc Id: ENSCLAP00000001000   ⟸   ENSCLAT00000001038
Protein Domains
EGF-like   TB


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCLAG00000000773 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCLAT00000001038 ENTREZGENE
  ENSCLAT00000001038.1 UniProtKB/TrEMBL
  ENSCLAT00000001039.1 UniProtKB/TrEMBL
  ENSCLAT00000001040.1 UniProtKB/TrEMBL
  ENSCLAT00000001041.1 UniProtKB/TrEMBL
Gene3D-CATH 3.90.290.10 UniProtKB/TrEMBL
  Laminin UniProtKB/TrEMBL
InterPro cEGF UniProtKB/TrEMBL
  EGF-like_Ca-bd_dom UniProtKB/TrEMBL
  EGF-like_CS UniProtKB/TrEMBL
  EGF-like_dom UniProtKB/TrEMBL
  EGF-type_Asp/Asn_hydroxyl_site UniProtKB/TrEMBL
  EGF_Ca-bd_CS UniProtKB/TrEMBL
  Growth_fac_rcpt_cys_sf UniProtKB/TrEMBL
  TB_dom UniProtKB/TrEMBL
  TB_dom_sf UniProtKB/TrEMBL
NCBI Gene Ltbp4 ENTREZGENE
PANTHER EGF-LIKE DOMAIN-CONTAINING PROTEIN UniProtKB/TrEMBL
  VACUOLAR-SORTING RECEPTOR 1 UniProtKB/TrEMBL
Pfam cEGF UniProtKB/TrEMBL
  EGF_CA UniProtKB/TrEMBL
  hEGF UniProtKB/TrEMBL
  PF00683 UniProtKB/TrEMBL
PROSITE ASX_HYDROXYL UniProtKB/TrEMBL
  EGF_1 UniProtKB/TrEMBL
  EGF_2 UniProtKB/TrEMBL
  EGF_3 UniProtKB/TrEMBL
  EGF_CA UniProtKB/TrEMBL
  PS51364 UniProtKB/TrEMBL
SMART EGF UniProtKB/TrEMBL
  EGF_CA UniProtKB/TrEMBL
Superfamily-SCOP EGF/Laminin UniProtKB/TrEMBL
  SSF57184 UniProtKB/TrEMBL
  SSF57581 UniProtKB/TrEMBL
UniProt A0A8C2UHF8_CHILA UniProtKB/TrEMBL
  A0A8C2UHG1_CHILA UniProtKB/TrEMBL
  A0A8C2UKC0 ENTREZGENE, UniProtKB/TrEMBL
  A0A8C2UMC5_CHILA UniProtKB/TrEMBL