Alkbh5 (alkB homolog 5, RNA demethylase)

Gene: Alkbh5 (alkB homolog 5, RNA demethylase) Chinchilla lanigera

Analyze

Symbol:

Alkbh5

Name:

alkB homolog 5, RNA demethylase

RGD ID:

9031978

Description:

ENCODES a protein that exhibits 2-oxoglutarate-dependent dioxygenase activity (ortholog); lysophospholipase activity (ortholog); molecular condensate scaffold activity (ortholog); INVOLVED IN gamma-delta T cell proliferation (ortholog); mRNA destabilization (ortholog); non-membrane-bounded organelle assembly (ortholog); ASSOCIATED WITH autistic disorder (ortholog); Birt-Hogg-Dube syndrome (ortholog); common variable immunodeficiency 2 (ortholog); FOUND IN cytosol (ortholog); Golgi apparatus (ortholog); nuclear speck (ortholog)

Type:

protein-coding

RefSeq Status:

MODEL

Previously known as:

alkB, alkylation repair homolog 5; RNA demethylase ALKBH5

RGD Orthologs

Alliance Genes

More Info

more info ...

Latest Assembly:

ChiLan1.0 - Chinchilla ChiLan1.0 Assembly

Position:

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955478	11,105,920 - 11,128,222 (-)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955478	11,104,445 - 11,128,980 (-)	NCBI	ChiLan1.0	ChiLan1.0

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

autistic disorder (ISO)

Birt-Hogg-Dube syndrome (ISO)

common variable immunodeficiency 2 (ISO)

genetic disease (ISO)

Joubert syndrome 1 (ISO)

multiple myeloma (ISO)

Potocki-Lupski syndrome (ISO)

pre-eclampsia (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

gamma-delta T cell proliferation (ISO)

mRNA destabilization (ISO)

non-membrane-bounded organelle assembly (ISO)

regulation of mRNA export from nucleus (ISO)

regulation of mRNA processing (ISO)

regulation of mRNA stability (ISO)

regulation of translation (ISO)

response to hypoxia (ISO)

spermatogenesis (ISO)

Cellular Component

cytosol (ISO)

Golgi apparatus (ISO)

nuclear speck (ISO)

nucleoplasm (ISO)

nucleus (ISO)

paraspeckles (ISO)

Molecular Function

2-oxoglutarate-dependent dioxygenase activity (ISO)

lysophospholipase activity (ISO)

molecular condensate scaffold activity (ISO)

mRNA N6-methyladenosine dioxygenase activity (ISO)

References

References - curated

#	Reference Title	Reference Citation
1.	Transitive Annotation Pipeline	Automated assignment of GO, PW and RDO ISO annotations across species

Additional References at PubMed

PMID:30032202

Genomics

Comparative Map Data

Alkbh5
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955478	11,105,920 - 11,128,222 (-)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955478	11,104,445 - 11,128,980 (-)	NCBI	ChiLan1.0	ChiLan1.0

ALKBH5
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	17	18,183,828 - 18,209,954 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	17	18,183,078 - 18,209,954 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	17	18,087,142 - 18,113,268 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	17	18,027,592 - 18,053,993 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Celera	17	19,028,003 - 19,054,331 (+)	NCBI		Celera
Cytogenetic Map	17	p11.2	NCBI
HuRef	17	17,840,215 - 17,866,584 (+)	NCBI		HuRef
CHM1_1	17	18,095,612 - 18,122,007 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	17	18,130,641 - 18,156,760 (+)	NCBI		T2T-CHM13v2.0

Alkbh5
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	11	60,428,509 - 60,449,338 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	11	60,427,207 - 60,449,338 (+)	Ensembl		GRCm39 Ensembl
GRCm38	11	60,537,683 - 60,558,512 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	11	60,536,381 - 60,558,512 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	11	60,351,185 - 60,372,014 (+)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	11	60,354,173 - 60,372,092 (+)	NCBI		MGSCv36	mm8
Celera	11	65,862,595 - 65,871,990 (-)	NCBI		Celera
Cytogenetic Map	11	B2	NCBI
cM Map	11	37.81	NCBI

Alkbh5
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	10	45,844,411 - 45,865,853 (+)	NCBI		GRCr8
mRatBN7.2	10	45,344,888 - 45,366,331 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	10	45,343,395 - 45,366,331 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	10	50,045,424 - 50,066,927 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	10	49,535,808 - 49,557,314 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	10	45,039,416 - 45,060,918 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	10	46,906,314 - 46,927,759 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	10	46,906,115 - 46,930,579 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	10	46,679,920 - 46,700,727 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	10	46,811,205 - 46,832,649 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	10	46,824,567 - 46,845,705 (+)	NCBI
Celera	10	44,601,477 - 44,622,922 (+)	NCBI		Celera
Cytogenetic Map	10	q22	NCBI

ALKBH5
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	19	53,057,922 - 53,085,590 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	17	57,769,067 - 57,795,721 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	17	32,725,632 - 32,753,021 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	17	38,003,362 - 38,030,715 (-)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	17	38,003,362 - 38,030,715 (-)	Ensembl	panpan1.1		panPan2

ALKBH5
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	5	41,339,292 - 41,365,641 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	5	41,343,241 - 41,364,547 (-)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	5	41,478,767 - 41,504,424 (-)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	5	41,445,991 - 41,471,674 (-)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	5	41,446,003 - 41,472,037 (-)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	5	41,413,849 - 41,439,509 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	5	41,361,292 - 41,386,942 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	5	41,553,123 - 41,578,789 (-)	NCBI		UU_Cfam_GSD_1.0

Alkbh5
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024405602	61,112,447 - 61,137,218 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936741	1,729,679 - 1,757,419 (+)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936741	1,729,707 - 1,756,108 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

ALKBH5
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	12	60,507,667 - 60,529,733 (-)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	12	60,507,662 - 60,530,239 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1

ALKBH5
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	16	17,221,643 - 17,249,038 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	16	17,222,378 - 17,249,117 (+)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666059	3,656,506 - 3,683,620 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Alkbh5
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624849	3,257,459 - 3,280,245 (-)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624849	3,257,460 - 3,280,870 (-)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Expression

Sequence

Nucleotide Sequences


RefSeq Transcripts	XM_005402287	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_013503226	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AGCD01056160	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AGCD01056161	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	GBCE01115231	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

RefSeq Acc Id:

ENSCLAT00000005467 ⟹ ENSCLAP00000005371

Type:

CODING

Position:

Chinchilla Assembly	Chr	Position (strand)	Source
ChiLan1.0 Ensembl	NW_004955478	11,105,920 - 11,128,222 (-)	Ensembl

RefSeq Acc Id:

XM_005402287 ⟹ XP_005402344

Type:

CODING

Position:

Chinchilla Assembly	Chr	Position (strand)	Source
ChiLan1.0	NW_004955478	11,104,445 - 11,128,976 (-)	NCBI

Sequence:

show sequence

AATAGGGCTGCCTAGGTTGTGGCGGTTCCTCGGTGATTGCGCGCTTGGGGCTGAGACATTTAAG
GGCATTCAGACGATGCTATGACGCGGCATAGCAACAGTGTTGACAGCGTGAGCGCACCCCAGCG
GAGGGAGCCCTTCGGTCCAGGAGGCGGCGCGACGTGGAGGCAGGTCGCTGTTTGAGAGTTCTCC
CTCGAAGCCCTTCAGCGAGTGGGGGAGGGGCGGCGGACAAGCAGTGGTGCCCTTGTGCGCTTGC
GCTGGCCCCGGTGCCGACCTGGCCCGCACGCACGCGCATGCCTACAGCGCGCCGAGCCGCGGCG
GCCGGAGACTCTGCGCCTGCGCGCCGAGGAGCCCGCTAAGGAGCGGCGCTGGCGGACGTCGGGC
GGGCGGCCTGTGACGTAGTGAGGAGAGCTTTAAAGTGCGGGCTGGGCCGGGTGTCGGAGGGTCT
GGCCGCGAGTCGGGCCGAGTCTCCTCCGCGGCCCTCCGCGGCATGAGGCGCTGCCGGCGCCCCT
GCCCCCCGGGACGTGGAGAAAGTGGAGGAGGAGGAAGTCTCGTCGTCGCCAGCGCTGCATGACC
CGCCACCCCGAGGCCCGACCCCGCGCCTGGCCGCTCGCCTCCCCCTGCCCGGTCCCCCGGCCGC
GGATGGGGGCCCGGCGCTGAGGAGCCCCTGCTCCCGGGGCCTGGGGCGCGTCCCCGAGAGCCAT
GCCCGGGCGCTCCACCCGCCCCGGAGGACCCTAGGTAGTCTCGCGGGGGCATGGCGGCCGCCAG
CGGCTACACGGACCTGCGAGAGAAGCTCAAGTCCATGACGTCCCGGGACAACTACAAGGCCGGG
AACCGGGAGGCCGCGGCCGCCGCCGCCGCCGCCGAACCTTACCCGGCGTCCGGGACCAAGCGCA
AGTATCAGGAGGACTCGGACCCGGAGCGCAGCGACTACGAGGAGCAGCAGCTGCAGAAGGAGGA
GGAGGCGCGCAAGGTGAAGAGCGGCATCCGCCAGATCCGCCTCTTCAGCCAGGACGAGTGCGCC
AAGATAGAGGCCCGCATCGACGAGGTGGTGTCCCGCGCCGAGAAGGGGCTGTACAACGAGCACA
CGGTGGACCGGGCCCCGCTGCGCAACAAGTACTTCTTCGGGGAGGGCTACACGTACGGCGCGCA
GCTGCAGAAGCGCGGGCCGGGCCAGGAGCGCCTGTACCCCCCGGGGGACGTGGACGAGATCCCC
GAGTGGGTGCACCAGTTGGTGATCCAGAAGCTGGTGGAGCACCGCGTCATTCCCGAGGGCTTCG
TCAACAGCGCCGTCATCAACGACTACCAGCCGGGAGGCTGCATCGTGTCTCACGTGGACCCCAT
CCACATATTTGAGCGCCCCATCGTGTCTGTGTCTTTCTTTAGCGATTCTGCGCTGTGCTTCGGC
TGCAAATTCCAGTTCAAGCCTATCCGGGTGTCAGAACCTGTGCTTTCCCTGCCGGTGCGCAGAG
GGAGCGTGACTGTGCTCAGTGGATATGCTGCTGATGAAATCACTCACTGCATACGGCCTCAGGA
CATCAAAGAGCGCCGAGCAGTCATCATCCTCAGGAAGACGAGACTAGACGCACCCCGGCTGGAA
ACAAAGTCCCTGAGCAGCTCCATTTTGCCACCCAGCTATGCTTCAGATCGCCTGTCAGGAAGCA
ACAGGGACCCTGCTGTGAAACCGAAGCGGTCGCACCGCAAGGCAGATCCTGATGCTGCCCACAG
GCCCCGGATCCTGGAGATGGACAAGGAAGAGAACCGGCGCTCAGTGCTGCTGCCCACCCACCGG
CGGAGGGGTAGCTTCAGCTCTGAGAACTACTGGCGCAAGTCCTATGAGTCTACGGAGGACTGCT
CAGAGGCAGCAGGCAGCCCTGCCCGAAAGGTGAAGATGCGGAGGCACTGAGGCATACTCACCAC
CCTCCTGGGAACTCTGGCTTCTCCTCACATAGCTGCCCCTCCTTTTGTTTTGTTTTGTTGGTTT
TTTGTTTGTTTTGTTTTTAATCTTATATATATTTTCCCTGATTCATTGCCCATTAAGGCTGAAG
AACAGAATTGACCTGGGTTCTTGTGTTCCTTCCTGGAAAGGCTGTTGGTGTTTGTTGGGGGCAG
AGGCTTGTGCTGGAGGAGCCAGTCAAGGTGTGGAATGGCCAGCCATCTTCAAGTGGGGCTGGGT
TTATTTAAAAGCAACAAAATGTTTTGGTTAAGAAATTTTCATTTTTGCTTTAAACATAAATCTT
TGCAGTGTTCTAAACAAAGTTCAGTTTCCTGCCTGCCCCTTTTCCTCCACTGATGTCTGCCCTT
GGTTGAGGTCTCCTGGAACCAGGCCGGCTCTGCATGGGGCAGCTTCCCCACCTCTGAACTGTTC
TACATCCTCTGGAAGCCCGTGTGGATACCTTCTCTTCTTCCTGTGGCAGAACTGTCTGGGTTGG
TGGGTGGTGGAGGACTTAATAATCCCAGCCCCTGCCCCCCCAAAGCTAGTGCTGAGCCCTCTGG
GCTGCCTCCGCACATTCTCGCGCTGCCAAGGGGCTAGCATGGTGGTCCTGACTTCTCTTGCCAA
GAGTGCACCTCTTTGCTGGGTTGCTCCTTTCAAACACGTGTGGGACTGTGTGGAAGTTAGACTT
GCCATGTTGGGTCATTTTAGGAGTTGTTTCTAGCTAGAGGGACTGACGTCCTTCCAAGTCAAGC
ATTTGGGGTGTGGGAAATCATTGTGGTGTATGGTAGGGTTTTTATTTTCTTTTTGAGTTATTTT
TTCCTTTGGTCTCTTGGCTTTCTCCTTTTCCTTTCCCCTTCATTGGTCAGCTTGGACCTCTTCC
CTGTGTCACCCTTCAGAAGGTGTCACCACCTCTGTTTGCCTGCAGCATGCATCCAAGGCCAGAG
CTCAGGCCTACAGACTAGGTTGGTACCTTCTCTGCCTCAGGGGCATGGGAGTTCAGGGAGGGGC
TTCTAAACAATAACAAAAAAAAGGCGAAGTCTTGGCAGTTTCTGTCTACTCAGATCCTAGAAGG
CTGTAAGGTCTTGCTGATCAGGATGCATTAGGAATGTCGTCTGGCCAGTCTGGCCAGGACCAGG
GCCTATCAAAAACACAGGCCCTCCTGGGAACCGGGCCACCACCAGTCTGGAGGGCTTTGAGTAG
AGTCCCCAGCCTTGAGACCACAGCGACTGCAGGAATCGGGGACAGCCACCATCAAGAAGCTCTT
CTCTGGGGCCAGAACTCCTTTGCCAGTGTGAATTCCTCAATTCGGGACTGCATAACTAAAGCAG
TTGCAGTTTTATTTTTTTTACAGCTTTTTTCCCAAAAATGATTTGTAGTTGTGTGTGCAGCACT
TTGCCCTGATATGTGTGCTCTACAATAAAAACCAAATCTAATATATTTTGAAA

hide sequence

RefSeq Acc Id:

XM_013503226 ⟹ XP_013358680

Type:

CODING

Position:

Chinchilla Assembly	Chr	Position (strand)	Source
ChiLan1.0	NW_004955478	11,104,445 - 11,128,980 (-)	NCBI

Sequence:

show sequence

CGGTAATAGGGCTGCCTAGGTTGTGGCGGTTCCTCGGTGATTGCGCGCTTGGGGCTGAGACATT
TAAGGGCATTCAGACGATGCTATGACGCGGCATAGCAACAGTGTTGACAGCGTGAGCGCACCCC
AGCGGAGGGAGCCCTTCGGTCCAGGAGGCGGCGCGACGTGGAGGCAGGTCGCTGTTTGAGAGTT
CTCCCTCGAAGCCCTTCAGCGAGTGGGGGAGGGGCGGCGGACAAGCAGTGGTGCCCTTGTGCGC
TTGCGCTGGCCCCGGTGCCGACCTGGCCCGCACGCACGCGCATGCCTACAGCGCGCCGAGCCGC
GGCGGCCGGAGACTCTGCGCCTGCGCGCCGAGGAGCCCGCTAAGGAGCGGCGCTGGCGGACGTC
GGGCGGGCGGCCTGTGACGTAGTGAGGAGAGCTTTAAAGTGCGGGCTGGGCCGGGTGTCGGAGG
GTCTGGCCGCGAGTCGGGCCGAGTCTCCTCCGCGGCCCTCCGCGGCATGAGGCGCTGCCGGCGC
CCCTGCCCCCCGGGACGTGGAGAAAGTGGAGGAGGAGGAAGTCTCGTCGTCGCCAGCGCTGCAT
GACCCGCCACCCCGAGGCCCGACCCCGCGCCTGGCCGCTCGCCTCCCCCTGCCCGGTCCCCCGG
CCGCGGATGGGGGCCCGGCGCTGAGGAGCCCCTGCTCCCGGGGCCTGGGGCGCGTCCCCGAGAG
CCATGCCCGGGCGCTCCACCCGCCCCGGAGGACCCTAGGTAGTCTCGCGGGGGCATGGCGGCCG
CCAGCGGCTACACGGACCTGCGAGAGAAGCTCAAGTCCATGACGTCCCGGGACAACTACAAGGC
CGGGAACCGGGAGGCCGCGGCCGCCGCCGCCGCCGCCGAACCTTACCCGGCGTCCGGGACCAAG
CGCAAGTATCAGGAGGACTCGGACCCGGAGCGCAGCGACTACGAGGAGCAGCAGCTGCAGAAGG
AGGAGGAGGCGCGCAAGGTGAAGAGCGGCATCCGCCAGATCCGCCTCTTCAGCCAGGACGAGTG
CGCCAAGATAGAGGCCCGCATCGACGAGGTGGTGTCCCGCGCCGAGAAGGGGCTGTACAACGAG
CACACGGTGGACCGGGCCCCGCTGCGCAACAAGTACTTCTTCGGGGAGGGCTACACGTACGGCG
CGCAGCTGCAGAAGCGCGGGCCGGGCCAGGAGCGCCTGTACCCCCCGGGGGACGTGGACGAGAT
CCCCGAGTGGGTGCACCAGTTGGTGATCCAGAAGCTGGTGGAGCACCGCGTCATTCCCGAGGGC
TTCGTCAACAGCGCCGTCATCAACGACTACCAGCCGGGAGGCTGCATCGTGTCTCACGTGGACC
CCATCCACATATTTGAGCGCCCCATCGTGTCTGTGTCTTTCTTTAGCGATTCTGCGCTGTGCTT
CGGCTGCAAATTCCAGTTCAAGCCTATCCGGGTGTCAGAACCTGTGCTTTCCCTGCCGGTGCGC
AGAGGGAGCGTGACTGTGCTCAGGACGAGACTAGACGCACCCCGGCTGGAAACAAAGTCCCTGA
GCAGCTCCATTTTGCCACCCAGCTATGCTTCAGATCGCCTGTCAGGAAGCAACAGGGACCCTGC
TGTGAAACCGAAGCGGTCGCACCGCAAGGCAGATCCTGATGCTGCCCACAGGCCCCGGATCCTG
GAGATGGACAAGGAAGAGAACCGGCGCTCAGTGCTGCTGCCCACCCACCGGCGGAGGGGTAGCT
TCAGCTCTGAGAACTACTGGCGCAAGTCCTATGAGTCTACGGAGGACTGCTCAGAGGCAGCAGG
CAGCCCTGCCCGAAAGGTGAAGATGCGGAGGCACTGAGGCATACTCACCACCCTCCTGGGAACT
CTGGCTTCTCCTCACATAGCTGCCCCTCCTTTTGTTTTGTTTTGTTGGTTTTTTGTTTGTTTTG
TTTTTAATCTTATATATATTTTCCCTGATTCATTGCCCATTAAGGCTGAAGAACAGAATTGACC
TGGGTTCTTGTGTTCCTTCCTGGAAAGGCTGTTGGTGTTTGTTGGGGGCAGAGGCTTGTGCTGG
AGGAGCCAGTCAAGGTGTGGAATGGCCAGCCATCTTCAAGTGGGGCTGGGTTTATTTAAAAGCA
ACAAAATGTTTTGGTTAAGAAATTTTCATTTTTGCTTTAAACATAAATCTTTGCAGTGTTCTAA
ACAAAGTTCAGTTTCCTGCCTGCCCCTTTTCCTCCACTGATGTCTGCCCTTGGTTGAGGTCTCC
TGGAACCAGGCCGGCTCTGCATGGGGCAGCTTCCCCACCTCTGAACTGTTCTACATCCTCTGGA
AGCCCGTGTGGATACCTTCTCTTCTTCCTGTGGCAGAACTGTCTGGGTTGGTGGGTGGTGGAGG
ACTTAATAATCCCAGCCCCTGCCCCCCCAAAGCTAGTGCTGAGCCCTCTGGGCTGCCTCCGCAC
ATTCTCGCGCTGCCAAGGGGCTAGCATGGTGGTCCTGACTTCTCTTGCCAAGAGTGCACCTCTT
TGCTGGGTTGCTCCTTTCAAACACGTGTGGGACTGTGTGGAAGTTAGACTTGCCATGTTGGGTC
ATTTTAGGAGTTGTTTCTAGCTAGAGGGACTGACGTCCTTCCAAGTCAAGCATTTGGGGTGTGG
GAAATCATTGTGGTGTATGGTAGGGTTTTTATTTTCTTTTTGAGTTATTTTTTCCTTTGGTCTC
TTGGCTTTCTCCTTTTCCTTTCCCCTTCATTGGTCAGCTTGGACCTCTTCCCTGTGTCACCCTT
CAGAAGGTGTCACCACCTCTGTTTGCCTGCAGCATGCATCCAAGGCCAGAGCTCAGGCCTACAG
ACTAGGTTGGTACCTTCTCTGCCTCAGGGGCATGGGAGTTCAGGGAGGGGCTTCTAAACAATAA
CAAAAAAAAGGCGAAGTCTTGGCAGTTTCTGTCTACTCAGATCCTAGAAGGCTGTAAGGTCTTG
CTGATCAGGATGCATTAGGAATGTCGTCTGGCCAGTCTGGCCAGGACCAGGGCCTATCAAAAAC
ACAGGCCCTCCTGGGAACCGGGCCACCACCAGTCTGGAGGGCTTTGAGTAGAGTCCCCAGCCTT
GAGACCACAGCGACTGCAGGAATCGGGGACAGCCACCATCAAGAAGCTCTTCTCTGGGGCCAGA
ACTCCTTTGCCAGTGTGAATTCCTCAATTCGGGACTGCATAACTAAAGCAGTTGCAGTTTTATT
TTTTTTACAGCTTTTTTCCCAAAAATGATTTGTAGTTGTGTGTGCAGCACTTTGCCCTGATATG
TGTGCTCTACAATAAAAACCAAATCTAATATATTTTGAAA

hide sequence

Protein Sequences


Protein RefSeqs	XP_005402344	(Get FASTA)	NCBI Sequence Viewer
	XP_013358680	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSCLAP00000005371
	ENSCLAP00000005371.1

RefSeq Acc Id:	XP_005402344 ⟸ XM_005402287
- Peptide Label:	isoform X1
- UniProtKB:	A0A8C2UT20 (UniProtKB/TrEMBL)
- Sequence:	show sequence MAAASGYTDLREKLKSMTSRDNYKAGNREAAAAAAAAEPYPASGTKRKYQEDSDPERSDYEEQQ LQKEEEARKVKSGIRQIRLFSQDECAKIEARIDEVVSRAEKGLYNEHTVDRAPLRNKYFFGEGY TYGAQLQKRGPGQERLYPPGDVDEIPEWVHQLVIQKLVEHRVIPEGFVNSAVINDYQPGGCIVS HVDPIHIFERPIVSVSFFSDSALCFGCKFQFKPIRVSEPVLSLPVRRGSVTVLSGYAADEITHC IRPQDIKERRAVIILRKTRLDAPRLETKSLSSSILPPSYASDRLSGSNRDPAVKPKRSHRKADP DAAHRPRILEMDKEENRRSVLLPTHRRRGSFSSENYWRKSYESTEDCSEAAGSPARKVKMRRH hide sequence

RefSeq Acc Id:	XP_013358680 ⟸ XM_013503226
- Peptide Label:	isoform X2
- UniProtKB:	A0A8C2UT20 (UniProtKB/TrEMBL)
- Sequence:	show sequence MAAASGYTDLREKLKSMTSRDNYKAGNREAAAAAAAAEPYPASGTKRKYQEDSDPERSDYEEQQ LQKEEEARKVKSGIRQIRLFSQDECAKIEARIDEVVSRAEKGLYNEHTVDRAPLRNKYFFGEGY TYGAQLQKRGPGQERLYPPGDVDEIPEWVHQLVIQKLVEHRVIPEGFVNSAVINDYQPGGCIVS HVDPIHIFERPIVSVSFFSDSALCFGCKFQFKPIRVSEPVLSLPVRRGSVTVLRTRLDAPRLET KSLSSSILPPSYASDRLSGSNRDPAVKPKRSHRKADPDAAHRPRILEMDKEENRRSVLLPTHRR RGSFSSENYWRKSYESTEDCSEAAGSPARKVKMRRH hide sequence

RefSeq Acc Id:

ENSCLAP00000005371 ⟸ ENSCLAT00000005467

Protein Domains

Alpha-ketoglutarate-dependent dioxygenase AlkB-like

Additional Information

External Database Links

Database	Acc Id	Source(s)
Ensembl Genes	ENSCLAG00000003812	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSCLAT00000005467	ENTREZGENE
	ENSCLAT00000005467.1	UniProtKB/TrEMBL
Gene3D-CATH	2.60.120.590	UniProtKB/TrEMBL
InterPro	AlkB-like	UniProtKB/TrEMBL
	AlkB-like_sf	UniProtKB/TrEMBL
	ALKBH5	UniProtKB/TrEMBL
NCBI Gene	Alkbh5	ENTREZGENE
PANTHER	PTHR32074	UniProtKB/TrEMBL
	RNA DEMETHYLASE ALKBH5	UniProtKB/TrEMBL
Pfam	2OG-FeII_Oxy_2	UniProtKB/TrEMBL
Superfamily-SCOP	Clavaminate synthase-like	UniProtKB/TrEMBL
UniProt	A0A8C2UT20	ENTREZGENE, UniProtKB/TrEMBL

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2015-08-25	Alkbh5	alkB homolog 5, RNA demethylase		alkB, alkylation repair homolog 5 (E. coli)	Symbol and/or name change	5135510	APPROVED

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD

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Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD