Syt8 (synaptotagmin 8) - Rat Genome Database

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Gene: Syt8 (synaptotagmin 8) Chinchilla lanigera
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Symbol: Syt8
Name: synaptotagmin 8
RGD ID: 9030930
Description: ENCODES a protein that exhibits calcium-dependent phospholipid binding (ortholog); calcium-dependent protein binding (ortholog); clathrin binding (ortholog); INVOLVED IN acrosome reaction (ortholog); ASSOCIATED WITH delta beta-thalassemia (ortholog); developmental and epileptic encephalopathy (ortholog); early infantile epileptic encephalopathy (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: synaptotagmin VIII; synaptotagmin-8
RGD Orthologs
Human
Mouse
Rat
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: ChiLan1.0 - Chinchilla ChiLan1.0 Assembly
Position:
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495542213,642,780 - 13,648,262 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495542213,642,933 - 13,648,351 (+)NCBIChiLan1.0ChiLan1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Transitive Annotation Pipeline Automated assignment of GO, PW and RDO ISO annotations across species
Additional References at PubMed
PMID:30032202  


Genomics

Comparative Map Data
Syt8
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495542213,642,780 - 13,648,262 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495542213,642,933 - 13,648,351 (+)NCBIChiLan1.0ChiLan1.0
SYT8
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38111,831,784 - 1,837,521 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl111,828,307 - 1,837,521 (+)EnsemblGRCh38hg38GRCh38
GRCh37111,855,657 - 1,858,751 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36111,812,250 - 1,815,326 (+)NCBINCBI36Build 36hg18NCBI36
Build 34111,812,281 - 1,815,326NCBI
Celera111,893,432 - 1,896,508 (+)NCBICelera
Cytogenetic Map11p15.5NCBI
HuRef111,646,573 - 1,649,649 (+)NCBIHuRef
CHM1_1111,854,481 - 1,857,557 (+)NCBICHM1_1
T2T-CHM13v2.0111,917,579 - 1,923,320 (+)NCBIT2T-CHM13v2.0
Syt8
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm397141,988,195 - 141,994,136 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl7141,988,587 - 141,994,133 (+)EnsemblGRCm39 Ensembl
GRCm387142,434,850 - 142,440,396 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl7142,434,850 - 142,440,396 (+)EnsemblGRCm38mm10GRCm38
MGSCv377149,620,882 - 149,626,303 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv367142,244,367 - 142,249,788 (+)NCBIMGSCv36mm8
Celera7142,190,658 - 142,196,079 (+)NCBICelera
Cytogenetic Map7F5NCBI
cM Map787.93NCBI
Syt8
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81207,017,602 - 207,023,076 (+)NCBIGRCr8
mRatBN7.21197,588,126 - 197,593,598 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1197,590,149 - 197,593,504 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1205,960,833 - 205,966,301 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01213,046,669 - 213,052,141 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01205,720,822 - 205,726,294 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01215,605,408 - 215,607,602 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1215,605,404 - 215,607,696 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01222,500,775 - 222,502,969 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41202,683,924 - 202,686,122 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11202,843,643 - 202,845,838 (+)NCBI
Celera1195,210,125 - 195,212,319 (+)NCBICelera
Cytogenetic Map1q41NCBI
SYT8
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v294,256,510 - 4,258,846 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1113,463,692 - 3,470,264 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0111,867,572 - 1,874,115 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1111,899,325 - 1,905,764 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl111,902,554 - 1,910,084 (+)Ensemblpanpan1.1panPan2
SYT8
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11846,069,380 - 46,075,477 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1846,072,495 - 46,075,480 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1844,676,051 - 44,685,670 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01846,752,813 - 46,756,815 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1846,753,883 - 46,756,729 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11846,194,603 - 46,204,217 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01845,774,910 - 45,784,524 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01846,521,011 - 46,530,630 (+)NCBIUU_Cfam_GSD_1.0
Syt8
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_0244049471,476,094 - 1,483,357 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936816732,565 - 737,309 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936816732,948 - 737,371 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
SYT8
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl21,247,878 - 1,250,437 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.121,245,988 - 1,250,422 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
SYT8
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.111,646,125 - 1,657,627 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl11,654,499 - 1,657,261 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366603898,850,358 - 98,853,662 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Syt8
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462476714,731,508 - 14,733,893 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462476714,673,307 - 14,733,984 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence


RefSeq Acc Id: ENSCLAT00000024234   ⟹   ENSCLAP00000024004
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_00495542213,642,780 - 13,648,262 (+)Ensembl
RefSeq Acc Id: XM_013514332   ⟹   XP_013369786
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_00495542213,644,880 - 13,648,351 (+)NCBI
Sequence:
RefSeq Acc Id: XM_013514333   ⟹   XP_013369787
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_00495542213,642,933 - 13,648,351 (+)NCBI
Sequence:
RefSeq Acc Id: XM_013514334   ⟹   XP_013369788
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_00495542213,642,933 - 13,648,351 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_013369786 (Get FASTA)   NCBI Sequence Viewer  
  XP_013369787 (Get FASTA)   NCBI Sequence Viewer  
  XP_013369788 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSCLAP00000024004
  ENSCLAP00000024004.1
RefSeq Acc Id: XP_013369787   ⟸   XM_013514333
- Peptide Label: isoform X2
- UniProtKB: A0A8C2W1Y7 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_013369788   ⟸   XM_013514334
- Peptide Label: isoform X2
- UniProtKB: A0A8C2W1Y7 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_013369786   ⟸   XM_013514332
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: ENSCLAP00000024004   ⟸   ENSCLAT00000024234
Protein Domains
C2


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCLAG00000016479 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCLAT00000024234 ENTREZGENE
  ENSCLAT00000024234.1 UniProtKB/TrEMBL
Gene3D-CATH 2.60.40.150 UniProtKB/TrEMBL
InterPro C2_dom UniProtKB/TrEMBL
  C2_domain_sf UniProtKB/TrEMBL
  Synaptotagmin UniProtKB/TrEMBL
NCBI Gene Syt8 ENTREZGENE
PANTHER PTHR10024:SF249 UniProtKB/TrEMBL
  SYNAPTOTAGMIN UniProtKB/TrEMBL
Pfam PF00168 UniProtKB/TrEMBL
PRINTS SYNAPTOTAGMN UniProtKB/TrEMBL
PROSITE PS50004 UniProtKB/TrEMBL
SMART SM00239 UniProtKB/TrEMBL
Superfamily-SCOP SSF49562 UniProtKB/TrEMBL
UniProt A0A8C2W1Y7 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-08-03 Syt8  synaptotagmin 8    synaptotagmin VIII  Symbol and/or name change 5135510 APPROVED