Pfdn2 (prefoldin subunit 2) - Rat Genome Database

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Gene: Pfdn2 (prefoldin subunit 2) Chinchilla lanigera
Analyze
Symbol: Pfdn2
Name: prefoldin subunit 2
RGD ID: 9027598
Description: ENCODES a protein that exhibits amyloid-beta binding (ortholog); protein folding chaperone (ortholog); unfolded protein binding (ortholog); INVOLVED IN negative regulation of amyloid fibril formation (ortholog); positive regulation of cytoskeleton organization (ortholog); protein folding (ortholog); ASSOCIATED WITH autoimmune interstitial lung, joint, and kidney disease (ortholog); gastrointestinal stromal tumor (ortholog); genetic disease (ortholog); FOUND IN cytoplasm (ortholog); cytosol (ortholog); mitochondrion (ortholog)
Type: protein-coding
RefSeq Status: MODEL
RGD Orthologs
Human
Mouse
Rat
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: ChiLan1.0 - Chinchilla ChiLan1.0 Assembly
Position:
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495546812,866,216 - 12,882,903 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495546812,868,582 - 12,882,884 (-)NCBIChiLan1.0ChiLan1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Transitive Annotation Pipeline Automated assignment of GO, PW and RDO ISO annotations across species
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Pfdn2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495546812,866,216 - 12,882,903 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495546812,868,582 - 12,882,884 (-)NCBIChiLan1.0ChiLan1.0
PFDN2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381161,100,561 - 161,118,037 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1161,100,556 - 161,118,055 (-)EnsemblGRCh38hg38GRCh38
GRCh371161,070,351 - 161,087,827 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361159,336,970 - 159,354,490 (-)NCBINCBI36Build 36hg18NCBI36
Build 341157,883,419 - 157,900,908NCBI
Celera1134,137,521 - 134,155,028 (-)NCBICelera
Cytogenetic Map1q23.3NCBI
HuRef1132,427,757 - 132,445,264 (-)NCBIHuRef
CHM1_11162,466,585 - 162,484,107 (-)NCBICHM1_1
T2T-CHM13v2.01160,238,042 - 160,255,506 (-)NCBIT2T-CHM13v2.0
Pfdn2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391171,172,522 - 171,186,822 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1171,173,238 - 171,186,822 (+)EnsemblGRCm39 Ensembl
GRCm381171,344,954 - 171,359,254 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1171,345,670 - 171,359,254 (+)EnsemblGRCm38mm10GRCm38
MGSCv371173,275,830 - 173,288,301 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361173,182,374 - 173,194,845 (+)NCBIMGSCv36mm8
Celera1173,797,189 - 173,809,573 (+)NCBICelera
Cytogenetic Map1H3NCBI
cM Map179.35NCBI
Pfdn2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81386,305,037 - 86,323,008 (+)NCBIGRCr8
mRatBN7.21383,772,301 - 83,791,367 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1383,753,877 - 83,790,504 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1386,279,144 - 86,296,329 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01387,677,355 - 87,694,540 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01384,913,445 - 84,930,319 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01389,725,113 - 89,743,849 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1389,725,869 - 89,743,848 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01394,352,458 - 94,371,424 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41387,246,113 - 87,263,293 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera1383,404,065 - 83,421,027 (+)NCBICelera
Cytogenetic Map13q24NCBI
PFDN2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2188,733,917 - 88,751,458 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1188,424,271 - 88,441,791 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01136,512,982 - 136,530,524 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11140,426,205 - 140,443,773 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1140,426,205 - 140,443,773 (-)Ensemblpanpan1.1panPan2
PFDN2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13821,355,622 - 21,367,623 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl3821,355,678 - 21,367,619 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha3821,429,654 - 21,441,700 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.03821,473,147 - 21,485,201 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl3821,473,208 - 21,485,197 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.13821,361,301 - 21,373,529 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.03821,775,330 - 21,787,369 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.03822,184,560 - 22,196,824 (+)NCBIUU_Cfam_GSD_1.0
Pfdn2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_0244050587,204,946 - 7,223,919 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936903413,604 - 432,566 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936903413,604 - 432,561 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
PFDN2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl489,326,798 - 89,342,325 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1489,326,781 - 89,341,608 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2497,183,746 - 97,198,386 (+)NCBISscrofa10.2Sscrofa10.2susScr3
PFDN2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1202,862,695 - 2,880,540 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl202,862,738 - 2,880,534 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660381,909,920 - 1,928,131 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Pfdn2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_004624794257,822 - 270,546 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_004624794257,740 - 270,776 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSCLAT00000018705   ⟹   ENSCLAP00000018523
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_00495546812,866,216 - 12,882,903 (-)Ensembl
RefSeq Acc Id: XM_005400251   ⟹   XP_005400308
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_00495546812,868,582 - 12,882,884 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_005400308 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSCLAP00000018523.1
Reference Protein Sequences
RefSeq Acc Id: XP_005400308   ⟸   XM_005400251
- Sequence:
RefSeq Acc Id: ENSCLAP00000018523   ⟸   ENSCLAT00000018705


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCLAG00000012708 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSCLAT00000018705.1 UniProtKB/TrEMBL
Gene3D-CATH 1.10.287.370 UniProtKB/TrEMBL
InterPro PFD2 UniProtKB/TrEMBL
  PFD_beta-like UniProtKB/TrEMBL
  Prefoldin UniProtKB/TrEMBL
NCBI Gene Pfdn2 ENTREZGENE
PANTHER PREFOLDIN SUBUNIT 2 UniProtKB/TrEMBL
  PTHR13303 UniProtKB/TrEMBL
Pfam Prefoldin_2 UniProtKB/TrEMBL
Superfamily-SCOP Prefoldin UniProtKB/TrEMBL
UniProt A0A8C2VPB1_CHILA UniProtKB/TrEMBL