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Gene: Kdm1a (lysine demethylase 1A) Chinchilla lanigera

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Symbol:

Kdm1a

Name:

lysine demethylase 1A

RGD ID:

9027317

Description:

ENCODES a protein that exhibits chromatin binding (ortholog); DNA-binding transcription factor binding (ortholog); enzyme binding (ortholog); INVOLVED IN cell differentiation (ortholog); cellular response to cAMP (ortholog); cellular response to gamma radiation (ortholog); PARTICIPATES IN histone modification pathway; Notch signaling pathway; ASSOCIATED WITH 3-hydroxy-3-methylglutaryl-CoA lyase deficiency (ortholog); ACTH-independent Macronodular Adrenal Hyperplasia 3 (ortholog); alopecia areata (ortholog); FOUND IN chromatin (ortholog); chromosome, telomeric region (ortholog); DNA repair complex (ortholog)

Type:

protein-coding

RefSeq Status:

MODEL

Previously known as:

lysine (K)-specific demethylase 1A; lysine-specific histone demethylase 1A

RGD Orthologs

Alliance Orthologs

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	KDM1A (lysine demethylase 1A)	NCBI	Ortholog
Mus musculus (house mouse):	Kdm1a (lysine (K)-specific demethylase 1A)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Rattus norvegicus (Norway rat):	Kdm1a (lysine demethylase 1A)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	KDM1A (lysine demethylase 1A)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	KDM1A (lysine demethylase 1A)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Kdm1a (lysine demethylase 1A)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	KDM1A (lysine demethylase 1A)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	KDM1A (lysine demethylase 1A)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Kdm1a (lysine demethylase 1A)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline

Latest Assembly:

ChiLan1.0 - Chinchilla ChiLan1.0 Assembly

NCBI Annotation Information:

Annotation category: partial on reference assembly

Position:

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955452	3,044,264 - 3,104,418 (+)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955452	3,044,042 - 3,104,650 (+)	NCBI	ChiLan1.0	ChiLan1.0

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

3-hydroxy-3-methylglutaryl-CoA lyase deficiency (ISO)

ACTH-independent Macronodular Adrenal Hyperplasia 3 (ISO)

alopecia areata (ISO)

breast cancer (ISO)

castration-resistant prostate carcinoma (ISO)

Cleft Palate, Psychomotor Retardation, and Distinctive Facial Features (ISO)

Colonic Neoplasms (ISO)

Critical Illness (ISO)

Developmental Disabilities (ISO)

diabetic retinopathy (ISO)

Diamond-Blackfan anemia (ISO)

Disease Progression (ISO)

Experimental Melanoma (ISO)

genetic disease (ISO)

hepatocellular carcinoma (ISO)

Hyperplasia (ISO)

intellectual disability (ISO)

lung non-small cell carcinoma (ISO)

melanoma (ISO)

Neoplasm Invasiveness (ISO)

schizophrenia (ISO)

T-cell non-Hodgkin lymphoma (ISO)

transient cerebral ischemia (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

cell differentiation (ISO)

cellular response to cAMP (ISO)

cellular response to gamma radiation (ISO)

cellular response to UV (ISO)

cerebral cortex development (ISO)

DNA repair-dependent chromatin remodeling (ISO)

granulocyte differentiation (ISO)

guanine metabolic process (ISO)

muscle cell development (ISO)

negative regulation of DNA damage response, signal transduction by p53 class mediator (ISO)

negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator (ISO)

negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator (ISO)

negative regulation of neurogenesis (ISO)

negative regulation of transcription by RNA polymerase II (ISO)

negative regulation of transcription initiation-coupled chromatin remodeling (ISO)

neuron maturation (ISO)

neuron projection extension (ISO)

pituitary gland development (ISO)

positive regulation of cell size (ISO)

positive regulation of chromatin binding (ISO)

positive regulation of cold-induced thermogenesis (ISO)

positive regulation of epithelial to mesenchymal transition (ISO)

positive regulation of erythrocyte differentiation (ISO)

positive regulation of megakaryocyte differentiation (ISO)

positive regulation of neural precursor cell proliferation (ISO)

positive regulation of neuroblast proliferation (ISO)

positive regulation of neuron projection development (ISO)

positive regulation of protein ubiquitination (ISO)

positive regulation of stem cell proliferation (ISO)

positive regulation of transcription by RNA polymerase II (ISO)

protein modification process (ISO)

regulation of double-strand break repair via homologous recombination (ISO)

regulation of neurogenesis (ISO)

regulation of primitive erythrocyte differentiation (ISO)

regulation of protein localization (ISO)

regulation of transcription by RNA polymerase II (ISO)

response to fungicide (ISO)

transcription by RNA polymerase II (ISO)

Cellular Component

chromatin (ISO)

chromosome, telomeric region (ISO)

DNA repair complex (ISO)

histone methyltransferase complex (ISO)

nucleoplasm (ISO)

nucleus (ISO)

protein-containing complex (ISO)

Molecular Function

chromatin binding (ISO)

DNA-binding transcription factor binding (ISO)

enzyme binding (ISO)

FAD-dependent H3K4me/H3K4me3 demethylase activity (ISO)

flavin adenine dinucleotide binding (ISO)

histone demethylase activity (ISO)

histone H3K4 demethylase activity (ISO)

histone H3K9 demethylase activity (ISO)

histone H3K9me2/H3K9me3 demethylase activity (ISO)

identical protein binding (ISO)

lncRNA binding (ISO)

MRF binding (ISO)

nuclear androgen receptor binding (ISO)

oxidoreductase activity (ISO)

p53 binding (ISO)

promoter-specific chromatin binding (ISO)

protein binding (ISO)

protein demethylase activity (ISO)

RNA polymerase II cis-regulatory region sequence-specific DNA binding (ISO)

RNA polymerase II-specific DNA-binding transcription factor binding (ISO)

telomeric DNA binding (ISO)

telomeric repeat-containing RNA binding (ISO)

transcription coactivator activity (ISO)

transcription corepressor activity (ISO)

transcription factor binding (ISO)

Molecular Pathway Annotations Click to see Annotation Detail View

histone modification pathway (ISO)

Notch signaling pathway (ISO)

References

References - curated

#	Reference Title	Reference Citation
1.	Transitive Annotation Pipeline	Automated assignment of GO, PW and RDO ISO annotations across species
2.	OMIM Disease Annotation Pipeline	OMIM Disease Annotation Pipeline

Additional References at PubMed

PMID:22301074	PMID:30032202

Genomics

Comparative Map Data

Kdm1a
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955452	3,044,264 - 3,104,418 (+)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955452	3,044,042 - 3,104,650 (+)	NCBI	ChiLan1.0	ChiLan1.0

KDM1A
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	1	23,019,468 - 23,083,689 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	1	23,019,443 - 23,083,689 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	1	23,345,961 - 23,410,182 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	1	23,218,533 - 23,282,771 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	1	23,091,251 - 23,155,490	NCBI
Celera	1	21,668,066 - 21,732,323 (+)	NCBI		Celera
Cytogenetic Map	1	p36.12	NCBI
HuRef	1	21,590,111 - 21,655,045 (+)	NCBI		HuRef
CHM1_1	1	23,458,660 - 23,522,895 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	1	22,845,130 - 22,909,357 (+)	NCBI		T2T-CHM13v2.0

Kdm1a
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	4	136,277,844 - 136,330,127 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	4	136,277,851 - 136,330,034 (-)	Ensembl		GRCm39 Ensembl
GRCm38	4	136,550,533 - 136,602,787 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	4	136,550,540 - 136,602,723 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	4	136,106,448 - 136,158,638 (-)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	4	135,822,633 - 135,874,786 (-)	NCBI		MGSCv36	mm8
Celera	4	134,744,880 - 134,796,951 (-)	NCBI		Celera
Cytogenetic Map	4	D3	NCBI
cM Map	4	68.8	NCBI

Kdm1a
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	5	154,066,436 - 154,121,913 (-)	NCBI		GRCr8
mRatBN7.2	5	148,782,976 - 148,838,319 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	5	148,782,976 - 148,838,319 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	5	151,480,546 - 151,535,814 (-)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	5	153,254,833 - 153,310,100 (-)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	5	153,236,837 - 153,292,108 (-)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	5	154,909,003 - 154,965,171 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	5	154,909,003 - 154,965,171 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	5	158,674,383 - 158,730,358 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	5	155,299,289 - 155,358,404 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
Celera	5	147,184,121 - 147,238,797 (-)	NCBI		Celera
Cytogenetic Map	5	q36	NCBI

KDM1A
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	1	203,863,445 - 203,927,430 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	1	202,966,436 - 203,030,428 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	1	22,205,624 - 22,269,571 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	1	23,153,066 - 23,217,693 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	1	23,153,066 - 23,217,692 (+)	Ensembl	panpan1.1		panPan2

KDM1A
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	2	76,313,742 - 76,375,716 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	2	76,156,434 - 76,375,632 (-)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	2	72,818,576 - 72,880,479 (-)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	2	76,872,072 - 76,934,039 (-)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	2	76,872,072 - 76,934,863 (-)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	2	73,694,139 - 73,755,941 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	2	74,702,184 - 74,764,063 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	2	75,705,895 - 75,767,600 (-)	NCBI		UU_Cfam_GSD_1.0

Kdm1a
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024405058	42,426,557 - 42,494,307 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936474	8,262,885 - 8,319,092 (+)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936474	8,262,913 - 8,319,089 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

KDM1A
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	6	80,903,424 - 80,971,873 (+)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	6	80,903,407 - 80,971,875 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	6	75,060,275 - 75,073,680 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3
Sscrofa10.2	6	74,939,358 - 74,992,403 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

KDM1A
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	20	109,592,761 - 109,657,885 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	20	109,593,074 - 109,657,839 (-)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666033	6,659,024 - 6,724,168 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Kdm1a
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla 1.0	NW_004624764	7,664,550 - 7,742,494 (+)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Sequence

Nucleotide Sequences


RefSeq Transcripts	XM_013519586	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_013519587	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AGCD01043910	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AGCD01043911	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AGCD01043912	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	GBBH01143986	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	GBDF01212309	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSCLAT00000010522 ⟹ ENSCLAP00000010392

Type:

CODING

Position:

Chinchilla Assembly	Chr	Position (strand)	Source
ChiLan1.0 Ensembl	NW_004955452	3,044,264 - 3,104,418 (+)	Ensembl

Ensembl Acc Id:

ENSCLAT00000010523 ⟹ ENSCLAP00000010393

Type:

CODING

Position:

Chinchilla Assembly	Chr	Position (strand)	Source
ChiLan1.0 Ensembl	NW_004955452	3,044,264 - 3,104,418 (+)	Ensembl

RefSeq Acc Id:

XM_013519586 ⟹ XP_013375040

Type:

CODING

Position:

Chinchilla Assembly	Chr	Position (strand)	Source
ChiLan1.0	NW_004955452	3,044,042 - 3,104,650 (+)	NCBI

Sequence:

show sequence

CCAGGATGCCGCTCTATGGCAGCTGGGAGGGGCGGGGCCCGTGGGCGGTGCGGGGCCTTTTTGT
CTAGACGCGGCGGGAGCGCGCACAGCTCGAGCATACGCGGCGGCGTTTGGCGGCGCGCGGGTTG
CGTGACGGGAGGCAAGGAGTGGAGAGGCTGCTCCGGACTCACGGAGCGACAGACCGAGTGGCTC
TTGCGGCCGTGGGCTGCCAGGCGGCCTGAGATGTTGTCCGGAAAGAAGGCAGCGGCGGCGGCGG
CGGCAGCGGCGGCGGCAGCGGCGGCCGGGACGGAGACCGGACCCGGGGCGGCGGGCGGCGCCGA
GAACGGCTCCGACGTGTCCGCGCCACCTGCGGGCCTGTCGGGCCCCTCCGAGGTCGGGCCCGGA
GCGGCCGGGGAGCGCACCCCCCGCAAGAAGGAGCCCCCGCGGGCCTCGCCCCCTGGCGGCCTGG
CCGAGCCGCCGGGGTCCACCGGACCCCAGGCCGGGCCCACCGTGGTGCCCGGGTCTGCGACCCC
CATGGAGACGGGAATATCGGAGACTCCGGAGGGGCGACGGACCAGCCGGCGCAAGCGGGCCAAG
GTGGAGTACCGAGAGATGGATGAAAGCTTGGCCAACCTCTCAGAAGATGAATATTATTCAGAAG
AAGAGAGGAACGCTAAAGCAGAGAAGGAAAAGAAGCTTCCCCCACCACCCCCTCAAGCCCCACC
CGAGGAAGAAAATGAAAGTGAGCCTGAGGAACCATCTGGGCGAGCAGGAGGACTTCAAGACGAC
AGTTCTGGAGGGTATGGAGACGGCCAAGCATCAGGTGTGGAGGGTGCAGCTTTCCAGAGTAGAC
TTCCCCACGACCGGATGACCTCTCAGGAAGCAGCCTGTTTCCCAGACATCATCAGCGGGCCTCA
GCAGACCCAGAAGGTTTTTCTGTTCATCAGAAACCGCACATTACAGTTGTGGTTGGATAATCCA
AAGATTCAGCTGACATTTGAGGCTACTCTCCAACAATTAGAAGCTCCTTATAACAGTGATACTG
TGCTTGTCCATCGAGTTCACAGTTATTTAGAGCGTCATGGTCTTATCAACTTTGGCATCTATAA
GAGGATAAAACCCTTACCAACTAAGAAGACAGGAAAGGTAATTATTATAGGCTCTGGAGTCTCA
GGCTTGGCAGCAGCCCGACAACTACAAAGTTTTGGAATGGATGTCACACTTCTGGAAGCCAGGG
ATCGGGTGGGTGGACGAGTTGCTACATTTCGCAAAGGAAACTATGTAGCAGATCTTGGAGCCAT
GGTAGTGACAGGTCTTGGAGGGAACCCCATGGCTGTGGTCAGCAAACAAGTAAATATGGAACTA
GCCAAGATCAAGCAAAAATGCCCACTTTATGAAGCCAACGGACAAGCTGTTCCTAAAGAGAAAG
ATGAAATGGTAGAGCAAGAATTTAACCGGTTGCTAGAAGCTACATCTTACCTTAGTCATCAGCT
AGACTTCAATGTCCTCAATAATAAGCCTGTGTCCCTTGGCCAGGCCTTGGAAGTTGTCATTCAG
TTACAAGAGAAGCATGTCAAAGACGAGCAGATTGAACATTGGAAGAAGATAGTGAAAACTCAGG
AAGAACTGAAAGAACTTCTTAATAAGATGGTAAACTTGAAAGAGAAAATTAAAGAACTCCATCA
ACAATACAAGGAAGCATCTGAAGTGAAGCCACCCAGAGACATTACTGCTGAGTTCTTAGTGAAA
AGCAAGCACAGGGATCTGACTGCCCTTTGCAAGGAATATGATGAATTAGCTGAAACACAAGGAA
AACTAGAAGAAAAACTTCAAGAATTGGAAGCCAATCCCCCGAGTGATGTGTATCTCTCATCAAG
AGATAGACAGATACTTGATTGGCATTTTGCAAATCTTGAATTTGCCAACGCCACACCTCTCTCT
ACCCTCTCCCTTAAACATTGGGATCAGGATGATGACTTTGAGTTTACCGGCAGCCACCTGACAG
TGAGGAATGGCTACTCCTGTGTGCCTGTGGCCTTAGCAGAAGGCCTCGACATTAAACTGAATAC
AGCAGTGCGGCAGGTTCGCTACACAGCGTCAGGATGTGAAGTGATCGCTGTGAACACTCGCTCC
ACAAGTCAAACCTTTATTTATAAGTGTGATGCAGTTCTCTGTACTCTTCCCCTGGGTGTGTTGA
AGCAGCAGCCACCAGCTGTTCAGTTTGTGCCACCTCTTCCTGAGTGGAAGACGTCTGCAGTCCA
GAGGATGGGATTTGGCAACCTTAACAAGGTGGTGTTGTGTTTTGACCGAGTGTTCTGGGATCCA
AGTGTCAATTTGTTCGGGCATGTTGGCAGCACAACTGCCAGCAGAGGGGAGCTCTTCCTCTTCT
GGAACCTCTACAAAGCTCCAATACTGTTGGCATTGGTAGCAGGAGAAGCTGCTGGCATCATGGA
AAACATAAGTGATGATGTGATTGTGGGCCGTTGCCTGGCCATTCTCAAGGGGATTTTTGGTAGC
AGTGCAGTGCCCCAGCCCAAGGAAACAGTGGTGTCTCGCTGGCGTGCTGATCCCTGGGCCCGGG
GCTCCTATTCCTATGTAGCTGCAGGATCATCTGGAAATGACTACGATCTGATGGCTCAGCCAAT
CACTCCCGGCCCCTCAATTCCAGGTGCTCCACAGCCAATCCCACGCCTCTTCTTCGCGGGAGAA
CATACAATCCGGAACTACCCAGCCACAGTCCATGGTGCTCTGCTGAGTGGACTGCGAGAAGCAG
GAAGGATTGCAGACCAGTTCCTGGGAGCCATGTACACTTTGCCTCGCCAAGCCACACCAGGTGT
CCCCGCACAGCAGTCCCCAAGCATGTGAGACAGGTGCGCTGTGGAGGACGACCCTGGGTCTCAC
TGTGAGCACAGCTCTTCTAGCAATACTAGACGGCACTGAGAAGCGCCTGCCCTGGCACCTGGGC
TCACAGGAGGAATCCTGTTCTTAAAGACTGAGGCAAGGAAGTGCTGTAAAGTAACATCTTAGTC
TCTTGGTGGTGGTTGTTTTTTGTTTTTTTTTTTTTAGTATTTTGAGAATAAAACTTCATACAAA
ATTA

hide sequence

RefSeq Acc Id:

XM_013519587 ⟹ XP_013375041

Type:

CODING

Position:

Chinchilla Assembly	Chr	Position (strand)	Source
ChiLan1.0	NW_004955452	3,044,042 - 3,104,650 (+)	NCBI

Sequence:

show sequence

CCAGGATGCCGCTCTATGGCAGCTGGGAGGGGCGGGGCCCGTGGGCGGTGCGGGGCCTTTTTGT
CTAGACGCGGCGGGAGCGCGCACAGCTCGAGCATACGCGGCGGCGTTTGGCGGCGCGCGGGTTG
CGTGACGGGAGGCAAGGAGTGGAGAGGCTGCTCCGGACTCACGGAGCGACAGACCGAGTGGCTC
TTGCGGCCGTGGGCTGCCAGGCGGCCTGAGATGTTGTCCGGAAAGAAGGCAGCGGCGGCGGCGG
CGGCAGCGGCGGCGGCAGCGGCGGCCGGGACGGAGACCGGACCCGGGGCGGCGGGCGGCGCCGA
GAACGGCTCCGACGTGTCCGCGCCACCTGCGGGCCTGTCGGGCCCCTCCGAGGTCGGGCCCGGA
GCGGCCGGGGAGCGCACCCCCCGCAAGAAGGAGCCCCCGCGGGCCTCGCCCCCTGGCGGCCTGG
CCGAGCCGCCGGGGTCCACCGGACCCCAGGCCGGGCCCACCGTGGTGCCCGGGTCTGCGACCCC
CATGGAGACGGGAATATCGGAGACTCCGGAGGGGCGACGGACCAGCCGGCGCAAGCGGGCCAAG
GTGGAGTACCGAGAGATGGATGAAAGCTTGGCCAACCTCTCAGAAGATGAATATTATTCAGAAG
AAGAGAGGAACGCTAAAGCAGAGAAGGAAAAGAAGCTTCCCCCACCACCCCCTCAAGCCCCACC
CGAGGAAGAAAATGAAAGTGAGCCTGAGGAACCATCTGGTGTGGAGGGTGCAGCTTTCCAGAGT
AGACTTCCCCACGACCGGATGACCTCTCAGGAAGCAGCCTGTTTCCCAGACATCATCAGCGGGC
CTCAGCAGACCCAGAAGGTTTTTCTGTTCATCAGAAACCGCACATTACAGTTGTGGTTGGATAA
TCCAAAGATTCAGCTGACATTTGAGGCTACTCTCCAACAATTAGAAGCTCCTTATAACAGTGAT
ACTGTGCTTGTCCATCGAGTTCACAGTTATTTAGAGCGTCATGGTCTTATCAACTTTGGCATCT
ATAAGAGGATAAAACCCTTACCAACTAAGAAGACAGGAAAGGTAATTATTATAGGCTCTGGAGT
CTCAGGCTTGGCAGCAGCCCGACAACTACAAAGTTTTGGAATGGATGTCACACTTCTGGAAGCC
AGGGATCGGGTGGGTGGACGAGTTGCTACATTTCGCAAAGGAAACTATGTAGCAGATCTTGGAG
CCATGGTAGTGACAGGTCTTGGAGGGAACCCCATGGCTGTGGTCAGCAAACAAGTAAATATGGA
ACTAGCCAAGATCAAGCAAAAATGCCCACTTTATGAAGCCAACGGACAAGCTGTTCCTAAAGAG
AAAGATGAAATGGTAGAGCAAGAATTTAACCGGTTGCTAGAAGCTACATCTTACCTTAGTCATC
AGCTAGACTTCAATGTCCTCAATAATAAGCCTGTGTCCCTTGGCCAGGCCTTGGAAGTTGTCAT
TCAGTTACAAGAGAAGCATGTCAAAGACGAGCAGATTGAACATTGGAAGAAGATAGTGAAAACT
CAGGAAGAACTGAAAGAACTTCTTAATAAGATGGTAAACTTGAAAGAGAAAATTAAAGAACTCC
ATCAACAATACAAGGAAGCATCTGAAGTGAAGCCACCCAGAGACATTACTGCTGAGTTCTTAGT
GAAAAGCAAGCACAGGGATCTGACTGCCCTTTGCAAGGAATATGATGAATTAGCTGAAACACAA
GGAAAACTAGAAGAAAAACTTCAAGAATTGGAAGCCAATCCCCCGAGTGATGTGTATCTCTCAT
CAAGAGATAGACAGATACTTGATTGGCATTTTGCAAATCTTGAATTTGCCAACGCCACACCTCT
CTCTACCCTCTCCCTTAAACATTGGGATCAGGATGATGACTTTGAGTTTACCGGCAGCCACCTG
ACAGTGAGGAATGGCTACTCCTGTGTGCCTGTGGCCTTAGCAGAAGGCCTCGACATTAAACTGA
ATACAGCAGTGCGGCAGGTTCGCTACACAGCGTCAGGATGTGAAGTGATCGCTGTGAACACTCG
CTCCACAAGTCAAACCTTTATTTATAAGTGTGATGCAGTTCTCTGTACTCTTCCCCTGGGTGTG
TTGAAGCAGCAGCCACCAGCTGTTCAGTTTGTGCCACCTCTTCCTGAGTGGAAGACGTCTGCAG
TCCAGAGGATGGGATTTGGCAACCTTAACAAGGTGGTGTTGTGTTTTGACCGAGTGTTCTGGGA
TCCAAGTGTCAATTTGTTCGGGCATGTTGGCAGCACAACTGCCAGCAGAGGGGAGCTCTTCCTC
TTCTGGAACCTCTACAAAGCTCCAATACTGTTGGCATTGGTAGCAGGAGAAGCTGCTGGCATCA
TGGAAAACATAAGTGATGATGTGATTGTGGGCCGTTGCCTGGCCATTCTCAAGGGGATTTTTGG
TAGCAGTGCAGTGCCCCAGCCCAAGGAAACAGTGGTGTCTCGCTGGCGTGCTGATCCCTGGGCC
CGGGGCTCCTATTCCTATGTAGCTGCAGGATCATCTGGAAATGACTACGATCTGATGGCTCAGC
CAATCACTCCCGGCCCCTCAATTCCAGGTGCTCCACAGCCAATCCCACGCCTCTTCTTCGCGGG
AGAACATACAATCCGGAACTACCCAGCCACAGTCCATGGTGCTCTGCTGAGTGGACTGCGAGAA
GCAGGAAGGATTGCAGACCAGTTCCTGGGAGCCATGTACACTTTGCCTCGCCAAGCCACACCAG
GTGTCCCCGCACAGCAGTCCCCAAGCATGTGAGACAGGTGCGCTGTGGAGGACGACCCTGGGTC
TCACTGTGAGCACAGCTCTTCTAGCAATACTAGACGGCACTGAGAAGCGCCTGCCCTGGCACCT
GGGCTCACAGGAGGAATCCTGTTCTTAAAGACTGAGGCAAGGAAGTGCTGTAAAGTAACATCTT
AGTCTCTTGGTGGTGGTTGTTTTTTGTTTTTTTTTTTTTAGTATTTTGAGAATAAAACTTCATA
CAAAATTA

hide sequence

Protein Sequences


Protein RefSeqs	XP_013375040	(Get FASTA)	NCBI Sequence Viewer
	XP_013375041	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSCLAP00000010392
	ENSCLAP00000010392.1
	ENSCLAP00000010393
	ENSCLAP00000010393.1

RefSeq Acc Id:	XP_013375040 ⟸ XM_013519586
- Peptide Label:	isoform X1
- UniProtKB:	A0A8C2YMX0 (UniProtKB/TrEMBL)
- Sequence:	show sequence MAAGRGGARGRCGAFLSRRGGSAHSSSIRGGVWRRAGCVTGGKEWRGCSGLTERQTEWLLRPWA ARRPEMLSGKKAAAAAAAAAAAAAAGTETGPGAAGGAENGSDVSAPPAGLSGPSEVGPGAAGER TPRKKEPPRASPPGGLAEPPGSTGPQAGPTVVPGSATPMETGISETPEGRRTSRRKRAKVEYRE MDESLANLSEDEYYSEEERNAKAEKEKKLPPPPPQAPPEEENESEPEEPSGRAGGLQDDSSGGY GDGQASGVEGAAFQSRLPHDRMTSQEAACFPDIISGPQQTQKVFLFIRNRTLQLWLDNPKIQLT FEATLQQLEAPYNSDTVLVHRVHSYLERHGLINFGIYKRIKPLPTKKTGKVIIIGSGVSGLAAA RQLQSFGMDVTLLEARDRVGGRVATFRKGNYVADLGAMVVTGLGGNPMAVVSKQVNMELAKIKQ KCPLYEANGQAVPKEKDEMVEQEFNRLLEATSYLSHQLDFNVLNNKPVSLGQALEVVIQLQEKH VKDEQIEHWKKIVKTQEELKELLNKMVNLKEKIKELHQQYKEASEVKPPRDITAEFLVKSKHRD LTALCKEYDELAETQGKLEEKLQELEANPPSDVYLSSRDRQILDWHFANLEFANATPLSTLSLK HWDQDDDFEFTGSHLTVRNGYSCVPVALAEGLDIKLNTAVRQVRYTASGCEVIAVNTRSTSQTF IYKCDAVLCTLPLGVLKQQPPAVQFVPPLPEWKTSAVQRMGFGNLNKVVLCFDRVFWDPSVNLF GHVGSTTASRGELFLFWNLYKAPILLALVAGEAAGIMENISDDVIVGRCLAILKGIFGSSAVPQ PKETVVSRWRADPWARGSYSYVAAGSSGNDYDLMAQPITPGPSIPGAPQPIPRLFFAGEHTIRN YPATVHGALLSGLREAGRIADQFLGAMYTLPRQATPGVPAQQSPSM hide sequence

RefSeq Acc Id:

XP_013375041 ⟸ XM_013519587

- Peptide Label:

isoform X2

- Sequence:

show sequence

MAAGRGGARGRCGAFLSRRGGSAHSSSIRGGVWRRAGCVTGGKEWRGCSGLTERQTEWLLRPWA
ARRPEMLSGKKAAAAAAAAAAAAAAGTETGPGAAGGAENGSDVSAPPAGLSGPSEVGPGAAGER
TPRKKEPPRASPPGGLAEPPGSTGPQAGPTVVPGSATPMETGISETPEGRRTSRRKRAKVEYRE
MDESLANLSEDEYYSEEERNAKAEKEKKLPPPPPQAPPEEENESEPEEPSGVEGAAFQSRLPHD
RMTSQEAACFPDIISGPQQTQKVFLFIRNRTLQLWLDNPKIQLTFEATLQQLEAPYNSDTVLVH
RVHSYLERHGLINFGIYKRIKPLPTKKTGKVIIIGSGVSGLAAARQLQSFGMDVTLLEARDRVG
GRVATFRKGNYVADLGAMVVTGLGGNPMAVVSKQVNMELAKIKQKCPLYEANGQAVPKEKDEMV
EQEFNRLLEATSYLSHQLDFNVLNNKPVSLGQALEVVIQLQEKHVKDEQIEHWKKIVKTQEELK
ELLNKMVNLKEKIKELHQQYKEASEVKPPRDITAEFLVKSKHRDLTALCKEYDELAETQGKLEE
KLQELEANPPSDVYLSSRDRQILDWHFANLEFANATPLSTLSLKHWDQDDDFEFTGSHLTVRNG
YSCVPVALAEGLDIKLNTAVRQVRYTASGCEVIAVNTRSTSQTFIYKCDAVLCTLPLGVLKQQP
PAVQFVPPLPEWKTSAVQRMGFGNLNKVVLCFDRVFWDPSVNLFGHVGSTTASRGELFLFWNLY
KAPILLALVAGEAAGIMENISDDVIVGRCLAILKGIFGSSAVPQPKETVVSRWRADPWARGSYS
YVAAGSSGNDYDLMAQPITPGPSIPGAPQPIPRLFFAGEHTIRNYPATVHGALLSGLREAGRIA
DQFLGAMYTLPRQATPGVPAQQSPSM

hide sequence

Ensembl Acc Id:

ENSCLAP00000010392 ⟸ ENSCLAT00000010522

Ensembl Acc Id:

ENSCLAP00000010393 ⟸ ENSCLAT00000010523

Protein Domains

SWIRM

Additional Information

External Database Links

Database	Acc Id	Source(s)
Ensembl Genes	ENSCLAG00000007181	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSCLAT00000010522	ENTREZGENE
	ENSCLAT00000010522.1	UniProtKB/TrEMBL
	ENSCLAT00000010523	ENTREZGENE
	ENSCLAT00000010523.1	UniProtKB/TrEMBL
Gene3D-CATH	1.10.10.10	UniProtKB/TrEMBL
	3.50.50.60	UniProtKB/TrEMBL
	3.90.660.10	UniProtKB/TrEMBL
	ATP synthase, gamma subunit, helix hairpin domain	UniProtKB/TrEMBL
InterPro	Amino_oxidase	UniProtKB/TrEMBL
	FAD/NAD-bd_sf	UniProtKB/TrEMBL
	Flavin_monoamine_oxidase	UniProtKB/TrEMBL
	Hist_Lys-spec_deMease	UniProtKB/TrEMBL
	Homeobox-like_sf	UniProtKB/TrEMBL
	SWIRM	UniProtKB/TrEMBL
	WH-like_DNA-bd_sf	UniProtKB/TrEMBL
NCBI Gene	Kdm1a	ENTREZGENE
PANTHER	FLAVIN MONOAMINE OXIDASE	UniProtKB/TrEMBL
	LYSINE-SPECIFIC HISTONE DEMETHYLASE 1A	UniProtKB/TrEMBL
Pfam	Amino_oxidase	UniProtKB/TrEMBL
	SWIRM	UniProtKB/TrEMBL
PIRSF	Histone_Lys-demethylase	UniProtKB/TrEMBL
PROSITE	SWIRM	UniProtKB/TrEMBL
Superfamily-SCOP	FAD-linked reductases, C-terminal domain	UniProtKB/TrEMBL
	SSF46689	UniProtKB/TrEMBL
	SSF51905	UniProtKB/TrEMBL
UniProt	A0A8C2YMW7_CHILA	UniProtKB/TrEMBL
	A0A8C2YMX0	ENTREZGENE, UniProtKB/TrEMBL

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2016-08-03	Kdm1a	lysine demethylase 1A		lysine (K)-specific demethylase 1A	Symbol and/or name change	5135510	APPROVED

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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Imported Disease Annotations - CTD

Imported Disease Annotations - OMIM

RGD Manual Annotations

Imported Annotations - PID (archival)

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Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD

Imported Disease Annotations - OMIM

RGD Manual Annotations

Imported Annotations - PID (archival)