Ido2 (indoleamine 2,3-dioxygenase 2)

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Gene: Ido2 (indoleamine 2,3-dioxygenase 2) Chinchilla lanigera

Analyze

Symbol:

Ido2

Name:

indoleamine 2,3-dioxygenase 2

RGD ID:

9026209

Description:

ENCODES a protein that exhibits indoleamine 2,3-dioxygenase activity (ortholog); INVOLVED IN tryptophan catabolic process to kynurenine (ortholog); PARTICIPATES IN kynurenine metabolic pathway; ASSOCIATED WITH Chemical and Drug Induced Liver Injury (ortholog); Endotoxemia (ortholog); liver cirrhosis (ortholog); FOUND IN cytoplasm (ortholog)

Type:

protein-coding

RefSeq Status:

MODEL

RGD Orthologs

Human

Mouse

Rat

Bonobo

Dog

Squirrel

Pig

Green Monkey

Naked Mole-Rat

Alliance Genes

More Info

more info ...

Latest Assembly:

ChiLan1.0 - Chinchilla ChiLan1.0 Assembly

NCBI Annotation Information:

Annotation category: partial on reference assembly

Position:

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955536	2,894,308 - 2,939,016 (-)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955536	2,894,410 - 2,938,862 (-)	NCBI	ChiLan1.0	ChiLan1.0

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

Chemical and Drug Induced Liver Injury (ISO)

Endotoxemia (ISO)

liver cirrhosis (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

tryptophan catabolic process to kynurenine (ISO)

Cellular Component

cytoplasm (ISO)

Molecular Function

indoleamine 2,3-dioxygenase activity (ISO)

protein binding (ISO)

Molecular Pathway Annotations Click to see Annotation Detail View

kynurenine metabolic pathway (ISO)

References

References - curated


1.	Automated assignment of GO, PW and RDO ISS annotations to Chinchilla, Squirrel, Bonobo and/or Dog genes from Human gene annotations

Genomics

Comparative Map Data

Ido2
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955536	2,894,308 - 2,939,016 (-)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955536	2,894,410 - 2,938,862 (-)	NCBI	ChiLan1.0	ChiLan1.0

IDO2
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38.p13 Ensembl	8	39,934,614 - 40,016,391 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh38	8	39,934,955 - 40,016,391 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh37	8	39,792,474 - 39,873,910 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	8	39,911,631 - 39,993,067 (+)	NCBI	NCBI36		hg18	NCBI36
Celera	8	38,744,208 - 38,825,740 (+)	NCBI
Cytogenetic Map	8	p11.21	NCBI
HuRef	8	38,325,410 - 38,406,972 (+)	NCBI		HuRef
CHM1_1	8	39,839,074 - 39,920,934 (+)	NCBI		CHM1_1

Ido2
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	8	25,021,908 - 25,066,430 (-)	NCBI	GRCm39		mm39
GRCm38	8	24,531,892 - 24,576,414 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	8	24,531,892 - 24,576,333 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	8	25,642,364 - 25,686,805 (-)	NCBI	GRCm37		mm9	NCBIm37
MGSCv36	8	25,997,999 - 26,041,878 (-)	NCBI			mm8
Celera	8	26,015,603 - 26,060,501 (-)	NCBI		Celera
Cytogenetic Map	8	A2	NCBI

Ido2
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Rnor_6.0	16	72,232,852 - 72,291,227 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	16	72,268,943 - 72,289,156 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	16	71,883,093 - 71,936,202 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	16	71,907,113 - 71,932,910 (+)	NCBI	RGSC3.4		rn4	RGSC3.4
Celera	16	65,358,465 - 65,396,778 (+)	NCBI		Celera
Cytogenetic Map	16	q12.5	NCBI

IDO2
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
PanPan1.1	8	36,657,311 - 36,717,606 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	8	36,665,240 - 36,717,420 (+)	Ensembl	panpan1.1		panPan2
Mhudiblu_PPA_v0	8	39,149,045 - 39,209,671 (+)	NCBI	Mhudiblu_PPA_v0		panPan3

IDO2
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1 Ensembl	16	25,319,035 - 25,385,515 (-)	Ensembl	CanFam3.1		canFam3	CanFam3.1
CanFam3.1	16	25,319,035 - 25,375,085 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1

Ido2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
SpeTri2.0	NW_004936843	595,237 - 649,390 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

IDO2
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	17	9,277,069 - 9,343,749 (+)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	17	9,277,039 - 9,344,405 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	17	10,830,092 - 10,897,040 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

IDO2
(Chlorocebus sabaeus - African green monkey)

Vervet Assembly	Chr	Position (strand)	Source	Genome Browsers
Vervet Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	8	37,951,810 - 38,027,689 (+)	NCBI
ChlSab1.1 Ensembl	8	37,959,078 - 38,027,632 (+)	Ensembl

Ido2
(Heterocephalus glaber - naked mole-rat)

Molerat Assembly	Chr	Position (strand)	Source	Genome Browsers
Molerat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla 1.0	NW_004624780	3,620,899 - 3,668,351 (-)	NCBI

Expression

Sequence

Nucleotide Sequences


RefSeq Transcripts	XM_013507732	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AGCD01070804	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AGCD01070805	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AGCD01070806	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	GBCQ01095138	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Reference Sequences

RefSeq Acc Id:

ENSCLAT00000004294 ⟹ ENSCLAP00000004212

RefSeq Status:

Type:

CODING

Position:

Chinchilla Assembly	Chr	Position (strand)	Source
ChiLan1.0 Ensembl	NW_004955536	2,894,308 - 2,939,016 (-)	Ensembl

RefSeq Acc Id:

XM_013507732 ⟹ XP_013363186

RefSeq Status:

Type:

CODING

Position:

Chinchilla Assembly	Chr	Position (strand)	Source
ChiLan1.0	NW_004955536	2,894,410 - 2,938,862 (-)	NCBI

Sequence:

show sequence

GCTCATGACAAGTTGGAATTCAACCTCAGTACAAAGTTCCACTACACCACAAGAGACAACCGAA
GGATTCAGTTTTGAACCTCCAATCTCTTGGGACGTTGATTATTTGGATGGGGTTGCTTCTGCAG
TGGCAGCTTCTGTGCAGTACTTGGAACAAAATTATGGATCCTCAAAGACAGAATTTGAAGATAA
CACTGCCATTGTGTTTAGAAAGATACCACATTTCTGAAGAGTATGGCTTTCTTCTTCCAAATCC
TCTGAAAGAACTTCCTGATTATTACCAACCCTGGATGGAAATTGCCAACAAACTTCCTTACTTG
ATCGAGAGTCACCAGCTTCGCACTTGTGTGAACAGGATGCCGCTGCTGAGCTGCCTCCGCCTGC
GCGACCACCGCCCGCAGCGCCTGGCGCACCTGCTGCTCAGCGCCATGGCCGCCGGCTTCGTCTG
GCAGGAGGGGGAGCGGCGGCCCGCGCAGGTACTGCCAAGAAATCTTGCCATTCCCTTTGTGGAA
GTCTCCAGGATCCTGGGACTCCCTCCTATCTTGGTCCATGCTGATGTGGTGCTGACGAACTGGA
CTAAAAAAGACCCAGGAGGACCTCTGGAAATCAGTAACCTGGAGACCATTGTGTCACTTCCCGG
GGGAGAGAGCCTGCGTGGCTTCGTGCTGGTGACAGTTCTGGTGGAGAAAGCAGCAGTGCCTGGG
ATTAAGGCCCTGGCTCAAGCCACCGGCGCCATCCTGCAGCCCAACGAGGACGCCTTGCTTAAGG
CCCTGCAGTGCCTGAGACTCTCAATCAAAGACATCACGAGTGCCTTGGGACAAATGCATGATTA
TGTAGACCCAGACATATTTTATGCAGTCATCCGGATCTTTCTTTCTGGATGGAAGGATAACCCG
GCGATGCCAGTGGGCCTGGTGTATGAAGGTGTCTCCACAGAGCCCATGGGGTACTCTGGAGGGA
GCGCGGCTCAGAGCACAGTGCTCCATGCTTTCGATGAGTTCCTGGGTGTCCGTCATAGCAAAGA
AAGTGCTGACTTTCTGTACAGAATGAGGGACTACATGCCTCCCTCACATAAGGCCTTCCTAGAA
GAAATCCACTCGGCTCCTTCGCTGAGGGACTACGTCCTGGCCCCTGGCCATGCCCGCTGTCTGG
AAGCTTATAACCTATGTCTGGAGGCCCTGGTGGAGCTGCGCAGCTACCACATCACCATAGTGAC
CAAATACCTCATCACAGCTGCAGCCAAAGCCAGGAGCAGGAGGCCAAGCCATCTCCCAGAACCC
CCACAGGCTCTAGAAAACAGAGGCACTGGTGGGTCTGCAGTTCTGAGCTTCCTGAAGAGCGTCA
GGGATCGGACTCTGGAGGCCATTCTCCACCCCCAGGGCCAGGGAGCCACCTTCTCCCCAGCAGG
GCACAGCCCCCAGGAGGGGGTAGGTGGGCTGGACAATGAGGGAATGGGCTCTGCTCTGTAGAAT
GCCATGTGCTCCTTTGCTGACAGCCATGTCTGAGAGCAGAGTTTATGTGGCTGGAAATACTCCT
GCCCTGGCTCATCACTGCCCAACAGCCAGCAGCTGTGGACTCTTCCCTATTCCGAGCCCTGCAG
AGCTGCTGTTTCCCACTTCCTGTGCCAGGTAAGAGAAAACCAATCTAAATTTCACAACCCAAAC
AAAATTGCCCATACACAGATTGCCTTGTTGATAGTATTTTCAGAGGGAAAATTCGCTTTATTCA
GTTGCTCAAGGATTAGAACAGTGCTTTCTTTGACTCCCGACCAGCCCTCTCTCCCTGCAAGTTC
TGAATTTGGTGGCAGGAAGTGGGGAATGCGCCAGTGGAGATGTGTGGGGAAGAGGATGTTGACA
GTAAAAACTTGGAAGGCACGGTGAGAAAATGAATAGTTAATGACGTGGGGGCCCGAGAGACTTT
TTCACATGTTGTATAGTTTTGCAAATTCTATTTTAATTCTCTTCTTTATTTTTAGAAGAATGTT
TTGTACTCCATACACTGGAAGTCTATGCTTGTAAAATGAATTAATTGACCCCTCAAAAATAAAT
GAGCCAACTAGGAATGTATAGTAAATTTACATGTTTAAGTGTGCAAATAAATGTAACTATTTTT
ATCA

hide sequence

Protein Sequences


Protein RefSeqs	XP_013363186	(Get FASTA)	NCBI Sequence Viewer

Reference Sequences

RefSeq Acc Id:

XP_013363186 ⟸ XM_013507732

- Sequence:

show sequence

MGLLLQWQLLCSTWNKIMDPQRQNLKITLPLCLERYHISEEYGFLLPNPLKELPDYYQPWMEIA
NKLPYLIESHQLRTCVNRMPLLSCLRLRDHRPQRLAHLLLSAMAAGFVWQEGERRPAQVLPRNL
AIPFVEVSRILGLPPILVHADVVLTNWTKKDPGGPLEISNLETIVSLPGGESLRGFVLVTVLVE
KAAVPGIKALAQATGAILQPNEDALLKALQCLRLSIKDITSALGQMHDYVDPDIFYAVIRIFLS
GWKDNPAMPVGLVYEGVSTEPMGYSGGSAAQSTVLHAFDEFLGVRHSKESADFLYRMRDYMPPS
HKAFLEEIHSAPSLRDYVLAPGHARCLEAYNLCLEALVELRSYHITIVTKYLITAAAKARSRRP
SHLPEPPQALENRGTGGSAVLSFLKSVRDRTLEAILHPQGQGATFSPAGHSPQEGVGGLDNEGM
GSAL

hide sequence

RefSeq Acc Id:

ENSCLAP00000004212 ⟸ ENSCLAT00000004294

Additional Information

External Database Links

Database	Acc Id	Source(s)
Ensembl Genes	ENSCLAG00000003005	Ensembl, ENTREZGENE
Ensembl Protein	ENSCLAP00000004212	ENTREZGENE
Ensembl Transcript	ENSCLAT00000004294	ENTREZGENE
NCBI Gene	Ido2	ENTREZGENE

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

Imported Disease Annotations - CTD

RGD Manual Annotations