Rubcnl (rubicon like autophagy enhancer) - Rat Genome Database

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Gene: Rubcnl (rubicon like autophagy enhancer) Chinchilla lanigera
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Symbol: Rubcnl
Name: rubicon like autophagy enhancer
RGD ID: 9025758
Description: ENCODES a protein that exhibits phosphatidylinositol-3-phosphate binding (ortholog); phosphatidylinositol-4-phosphate binding (ortholog); phosphatidylinositol-5-phosphate binding (ortholog); INVOLVED IN autophagosome maturation (ortholog); autophagosome-endosome fusion (ortholog); autophagosome-lysosome fusion (ortholog); ASSOCIATED WITH genetic disease (ortholog); prostate cancer (ortholog); FOUND IN autophagosome membrane (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: KIAA0226-like ortholog; Kiaa0226l; rubicon like autophagy regulator; RUN and cysteine rich domain containing beclin 1 interacting protein like; uncharacterized protein KIAA0226-like homolog
RGD Orthologs
Human
Mouse
Rat
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: ChiLan1.0 - Chinchilla ChiLan1.0 Assembly
Position:
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955431140,922 - 206,951 (-)EnsemblChiLan1.0
ChiLan1.0NW_004955431140,999 - 206,570 (-)NCBIChiLan1.0ChiLan1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Transitive Annotation Pipeline Automated assignment of GO, PW and RDO ISO annotations across species
Additional References at PubMed
PMID:30032202  


Genomics

Comparative Map Data
Rubcnl
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955431140,922 - 206,951 (-)EnsemblChiLan1.0
ChiLan1.0NW_004955431140,999 - 206,570 (-)NCBIChiLan1.0ChiLan1.0
RUBCNL
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381346,334,681 - 46,390,042 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1346,334,681 - 46,438,190 (-)EnsemblGRCh38hg38GRCh38
GRCh371346,908,816 - 46,964,177 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361345,814,137 - 45,859,636 (-)NCBINCBI36Build 36hg18NCBI36
Build 341345,815,100 - 45,859,385NCBI
Celera1327,971,122 - 28,016,591 (-)NCBICelera
Cytogenetic Map13q14.13NCBI
HuRef1327,713,683 - 27,759,154 (-)NCBIHuRef
CHM1_11346,884,932 - 46,930,398 (-)NCBICHM1_1
T2T-CHM13v2.01345,555,685 - 45,611,047 (-)NCBIT2T-CHM13v2.0
Rubcnl
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391475,253,467 - 75,289,977 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1475,253,467 - 75,289,972 (+)EnsemblGRCm39 Ensembl
GRCm381475,015,987 - 75,052,537 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1475,016,027 - 75,052,532 (+)EnsemblGRCm38mm10GRCm38
MGSCv371475,415,834 - 75,452,339 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361473,736,988 - 73,786,572 (+)NCBIMGSCv36mm8
Celera1472,515,864 - 72,552,426 (+)NCBICelera
Cytogenetic Map14D3NCBI
cM Map1439.53NCBI
Rubcnl
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81556,741,897 - 56,807,086 (+)NCBIGRCr8
mRatBN7.21550,332,458 - 50,377,494 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1550,332,418 - 50,400,849 (+)EnsemblmRatBN7.2 Ensembl
Rnor_6.01557,065,512 - 57,109,197 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1557,065,428 - 57,102,599 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01560,777,541 - 60,821,362 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41555,894,968 - 55,913,448 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11555,815,486 - 55,929,226 (+)NCBI
Celera1549,964,999 - 50,008,655 (+)NCBICelera
Cytogenetic Map15q11NCBI
RUBCNL
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21444,953,710 - 45,049,079 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11336,007,854 - 36,111,800 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01326,594,545 - 26,600,412 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
RUBCNL
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1224,874,384 - 4,903,044 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl224,874,575 - 4,903,033 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha224,916,030 - 4,953,319 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0224,980,314 - 5,017,734 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl224,976,624 - 5,016,959 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1224,762,415 - 4,800,374 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0224,825,919 - 4,863,052 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0224,830,727 - 4,868,748 (+)NCBIUU_Cfam_GSD_1.0
Rubcnl
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024404945156,428,120 - 156,521,426 (-)NCBIHiC_Itri_2
SpeTri2.0NW_004936857839,418 - 870,961 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
RUBCNL
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1120,995,688 - 21,036,014 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11120,995,439 - 21,036,429 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21121,427,767 - 21,445,259 (+)NCBISscrofa10.2Sscrofa10.2susScr3
RUBCNL
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1324,400,507 - 24,445,514 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl324,399,500 - 24,430,601 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605719,554,526 - 19,600,019 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Rubcnl
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046247488,605,272 - 8,652,785 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence


RefSeq Acc Id: ENSCLAT00000005286   ⟹   ENSCLAP00000005190
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_004955431140,922 - 206,951 (-)Ensembl
RefSeq Acc Id: XM_005387542   ⟹   XP_005387599
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_004955431140,999 - 205,881 (-)NCBI
Sequence:
RefSeq Acc Id: XM_005387544   ⟹   XP_005387601
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_004955431140,999 - 206,570 (-)NCBI
Sequence:
RefSeq Acc Id: XM_005387545   ⟹   XP_005387602
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_004955431140,999 - 206,114 (-)NCBI
Sequence:
RefSeq Acc Id: XM_013515872   ⟹   XP_013371326
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_004955431140,999 - 205,881 (-)NCBI
Sequence:
RefSeq Acc Id: XM_013515873   ⟹   XP_013371327
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_004955431140,999 - 206,114 (-)NCBI
Sequence:
RefSeq Acc Id: XM_013515874   ⟹   XP_013371328
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_004955431140,999 - 205,881 (-)NCBI
Sequence:
RefSeq Acc Id: XM_013515875   ⟹   XP_013371329
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_004955431140,999 - 185,491 (-)NCBI
Sequence:
RefSeq Acc Id: XP_005387601   ⟸   XM_005387544
- Peptide Label: isoform X3
- UniProtKB: A0A8C2UXN3 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_005387602   ⟸   XM_005387545
- Peptide Label: isoform X3
- UniProtKB: A0A8C2UXN3 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_005387599   ⟸   XM_005387542
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: XP_013371327   ⟸   XM_013515873
- Peptide Label: isoform X3
- UniProtKB: A0A8C2UXN3 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_013371328   ⟸   XM_013515874
- Peptide Label: isoform X4
- Sequence:
RefSeq Acc Id: XP_013371326   ⟸   XM_013515872
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_013371329   ⟸   XM_013515875
- Peptide Label: isoform X5
- Sequence:
RefSeq Acc Id: ENSCLAP00000005190   ⟸   ENSCLAT00000005286
Protein Domains
Rubicon Homology


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCLAG00000003683 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCLAT00000005286 ENTREZGENE
  ENSCLAT00000005286.1 UniProtKB/TrEMBL
InterPro RUBC_PIKBD UniProtKB/TrEMBL
  Zf-RING_9 UniProtKB/TrEMBL
NCBI Gene Kiaa0226l ENTREZGENE
PANTHER PHOX (PX) DOMAIN-CONTAINING PROTEIN UniProtKB/TrEMBL
  PROTEIN ASSOCIATED WITH UVRAG AS AUTOPHAGY ENHANCER UniProtKB/TrEMBL
Pfam RUBC_PIKBD UniProtKB/TrEMBL
  zf-RING_9 UniProtKB/TrEMBL
SMART DUF4206 UniProtKB/TrEMBL
UniProt A0A8C2UXN3 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2019-01-01 Rubcnl  rubicon like autophagy enhancer    rubicon like autophagy regulator  Symbol and/or name change 5135510 APPROVED
2018-12-05 Rubcnl  rubicon like autophagy regulator    RUN and cysteine rich domain containing beclin 1 interacting protein like  Symbol and/or name change 5135510 APPROVED
2016-08-03 Rubcnl  RUN and cysteine rich domain containing beclin 1 interacting protein like  Kiaa0226l  KIAA0226-like ortholog  Symbol and/or name change 5135510 APPROVED