Inhbb (inhibin subunit beta B) - Rat Genome Database

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Gene: Inhbb (inhibin subunit beta B) Chinchilla lanigera
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Symbol: Inhbb
Name: inhibin subunit beta B
RGD ID: 9025655
Description: ENCODES a protein that exhibits protein homodimerization activity (ortholog); INVOLVED IN activin receptor signaling pathway (ortholog); apoptotic signaling pathway (ortholog); cellular response to calcium ion (ortholog); ASSOCIATED WITH Brain Death (ortholog); congenital hypothyroidism (ortholog); familial male-limited precocious puberty (ortholog); FOUND IN cell periphery (ortholog); extracellular space (ortholog); perinuclear region of cytoplasm (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: inhibin beta B chain; inhibin beta B subunit; inhibin, beta B
RGD Orthologs
Human
Mouse
Rat
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: ChiLan1.0 - Chinchilla ChiLan1.0 Assembly
NCBI Annotation Information: Annotation category: partial on reference assembly
Position:
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554599,482,873 - 9,488,489 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554599,482,998 - 9,488,489 (-)NCBIChiLan1.0ChiLan1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Transitive Annotation Pipeline Automated assignment of GO, PW and RDO ISO annotations across species
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Inhbb
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554599,482,873 - 9,488,489 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554599,482,998 - 9,488,489 (-)NCBIChiLan1.0ChiLan1.0
INHBB
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382120,346,136 - 120,351,803 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2120,346,136 - 120,351,803 (+)EnsemblGRCh38hg38GRCh38
GRCh372121,103,712 - 121,109,379 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 362120,820,189 - 120,825,853 (+)NCBINCBI36Build 36hg18NCBI36
Build 342120,819,228 - 120,825,204NCBI
Celera2114,430,578 - 114,436,242 (+)NCBICelera
Cytogenetic Map2q14.2NCBI
HuRef2113,427,651 - 113,433,082 (+)NCBIHuRef
CHM1_12121,108,004 - 121,113,654 (+)NCBICHM1_1
T2T-CHM13v2.02120,780,882 - 120,786,549 (+)NCBIT2T-CHM13v2.0
Inhbb
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391119,343,193 - 119,349,978 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1119,343,195 - 119,349,978 (-)EnsemblGRCm39 Ensembl
GRCm381119,415,463 - 119,422,248 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1119,415,465 - 119,422,248 (-)EnsemblGRCm38mm10GRCm38
MGSCv371121,312,042 - 121,318,825 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361121,243,011 - 121,249,794 (-)NCBIMGSCv36mm8
Celera1122,074,716 - 122,081,040 (-)NCBICelera
Cytogenetic Map1E2.3NCBI
cM Map152.29NCBI
Inhbb
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81333,083,671 - 33,089,373 (-)NCBIGRCr8
mRatBN7.21330,530,860 - 30,536,566 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1330,530,860 - 30,537,832 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1333,113,093 - 33,118,804 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01334,400,910 - 34,406,621 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01331,675,032 - 31,680,728 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01335,436,532 - 35,442,222 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1335,436,532 - 35,442,222 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01340,555,699 - 40,561,388 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41332,170,987 - 32,176,689 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11332,178,994 - 32,179,566 (-)NCBI
Celera1330,428,301 - 30,433,886 (-)NCBICelera
Cytogenetic Map13q11NCBI
INHBB
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21322,348,480 - 22,354,168 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12B22,363,449 - 22,369,137 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02B7,278,944 - 7,284,632 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12B120,857,849 - 120,860,564 (+)NCBIpanpan1.1PanPan1.1panPan2
INHBB
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11929,765,697 - 29,768,485 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1929,767,682 - 29,768,077 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1930,022,868 - 30,028,528 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01931,138,047 - 31,143,715 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1931,140,035 - 31,144,819 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11929,828,236 - 29,833,891 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01929,997,586 - 30,003,232 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01931,183,308 - 31,188,970 (-)NCBIUU_Cfam_GSD_1.0
Inhbb
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440530391,426,259 - 91,431,684 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493646950,186,036 - 50,191,461 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493646950,186,036 - 50,191,455 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
INHBB
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1530,999,520 - 31,004,405 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11530,999,994 - 31,004,405 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
INHBB
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1109,943,015 - 9,948,721 (-)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366606112,740,168 - 12,745,889 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Inhbb
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462473224,754,618 - 24,755,995 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462473224,754,601 - 24,755,890 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSCLAT00000003712   ⟹   ENSCLAP00000003638
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_0049554599,482,873 - 9,488,489 (-)Ensembl
RefSeq Acc Id: XM_013521093   ⟹   XP_013376547
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_0049554599,482,998 - 9,488,489 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_013376547 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSCLAP00000003638
  ENSCLAP00000003638.1
RefSeq Acc Id: XP_013376547   ⟸   XM_013521093
- UniProtKB: A0A8C2UPK7 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSCLAP00000003638   ⟸   ENSCLAT00000003712
Protein Domains
TGF-beta family profile


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCLAG00000002594 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCLAT00000003712 ENTREZGENE
  ENSCLAT00000003712.1 UniProtKB/TrEMBL
Gene3D-CATH 2.10.90.10 UniProtKB/TrEMBL
  2.60.120.970 UniProtKB/TrEMBL
InterPro Cystine-knot_cytokine UniProtKB/TrEMBL
  Inhibin_betaB UniProtKB/TrEMBL
  TGF-b_C UniProtKB/TrEMBL
  TGF-b_propeptide UniProtKB/TrEMBL
  TGF-beta-rel UniProtKB/TrEMBL
  TGFb_CS UniProtKB/TrEMBL
NCBI Gene Inhbb ENTREZGENE
PANTHER PTHR11848 UniProtKB/TrEMBL
  PTHR11848:SF29 UniProtKB/TrEMBL
Pfam TGF_beta UniProtKB/TrEMBL
  TGFb_propeptide UniProtKB/TrEMBL
PRINTS INHIBINBB UniProtKB/TrEMBL
PROSITE TGF_BETA_1 UniProtKB/TrEMBL
  TGF_BETA_2 UniProtKB/TrEMBL
SMART TGFB UniProtKB/TrEMBL
Superfamily-SCOP SSF57501 UniProtKB/TrEMBL
UniProt A0A8C2UPK7 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2018-05-01 Inhbb  inhibin subunit beta B    inhibin beta B subunit  Symbol and/or name change 5135510 APPROVED
2016-08-03 Inhbb  inhibin beta B subunit    inhibin, beta B  Symbol and/or name change 5135510 APPROVED