Aqp11 (aquaporin 11) - Rat Genome Database

Name: Aqp11
Creator: Rat Genome Database
License: Creative Commons CC BY 4.0
Keywords: Rat Gene RGD Genome

Gene: Aqp11 (aquaporin 11) Chinchilla lanigera

Analyze

Symbol:

Aqp11

Name:

aquaporin 11

RGD ID:

9024043

Description:

ENCODES a protein that exhibits glycerol channel activity (ortholog); identical protein binding (ortholog); water channel activity (ortholog); INVOLVED IN endosomal lumen acidification (ortholog); glycerol transmembrane transport (ortholog); hydrogen peroxide transmembrane transport (ortholog); ASSOCIATED WITH genetic disease (ortholog); intellectual disability (ortholog); FOUND IN cell surface (ortholog); cytoplasm (ortholog); dendrite (ortholog)

Type:

protein-coding

RefSeq Status:

MODEL

Previously known as:

aquaporin-11

RGD Orthologs

Alliance Genes

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	AQP11 (aquaporin 11)	NCBI	Ortholog
Mus musculus (house mouse):	Aqp11 (aquaporin 11)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Rattus norvegicus (Norway rat):	Aqp11 (aquaporin 11)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	AQP11 (aquaporin 11)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	AQP11 (aquaporin 11)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Aqp11 (aquaporin 11)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	AQP11 (aquaporin 11)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	AQP11 (aquaporin 11)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Aqp11 (aquaporin 11)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline

Latest Assembly:

ChiLan1.0 - Chinchilla ChiLan1.0 Assembly

Position:

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955414	14,245,682 - 14,260,717 (-)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955414	14,245,682 - 14,260,717 (-)	NCBI	ChiLan1.0	ChiLan1.0

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

genetic disease (ISO)

intellectual disability (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

endosomal lumen acidification (ISO)

glycerol transmembrane transport (ISO)

hydrogen peroxide transmembrane transport (ISO)

intracellular oxygen homeostasis (ISO)

intracellular water homeostasis (ISO)

kidney development (ISO)

monoatomic ion transport (ISO)

negative regulation of epithelial cell proliferation (ISO)

negative regulation of ERAD pathway (ISO)

negative regulation of response to endoplasmic reticulum stress (ISO)

positive regulation of cell population proliferation (ISO)

protein glycosylation (ISO)

protein homooligomerization (ISO)

protein targeting to membrane (ISO)

proximal tubule development (ISO)

urea transport (ISO)

water transport (ISO)

Cellular Component

cell surface (ISO)

cytoplasm (ISO)

dendrite (ISO)

endoplasmic reticulum (ISO)

intracellular membrane-bounded organelle (ISO)

perinuclear region of cytoplasm (ISO)

plasma membrane (ISO)

Molecular Function

glycerol channel activity (ISO)

identical protein binding (ISO)

water channel activity (ISO)

References

References - curated

#	Reference Title	Reference Citation
1.	Transitive Annotation Pipeline	Automated assignment of GO, PW and RDO ISO annotations across species

Additional References at PubMed

PMID:30032202

Genomics

Comparative Map Data

Aqp11
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955414	14,245,682 - 14,260,717 (-)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955414	14,245,682 - 14,260,717 (-)	NCBI	ChiLan1.0	ChiLan1.0

AQP11
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	11	77,589,953 - 77,610,356 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	11	77,589,391 - 77,610,356 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	11	77,300,998 - 77,321,401 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	11	76,978,328 - 76,998,342 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	11	76,978,327 - 76,998,339	NCBI
Celera	11	74,608,361 - 74,629,072 (+)	NCBI		Celera
Cytogenetic Map	11	q14.1	NCBI
HuRef	11	73,599,078 - 73,619,798 (+)	NCBI		HuRef
CHM1_1	11	77,183,785 - 77,204,503 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	11	77,523,008 - 77,543,410 (+)	NCBI		T2T-CHM13v2.0

Aqp11
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	7	97,375,586 - 97,387,454 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	7	97,373,213 - 97,387,496 (-)	Ensembl		GRCm39 Ensembl
GRCm38	7	97,726,379 - 97,738,247 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	7	97,724,006 - 97,738,289 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	7	104,874,889 - 104,886,757 (-)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	7	97,601,571 - 97,613,439 (-)	NCBI		MGSCv36	mm8
Celera	7	98,046,312 - 98,058,532 (-)	NCBI		Celera
Cytogenetic Map	7	E1	NCBI
cM Map	7	53.57	NCBI

Aqp11
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	1	161,457,752 - 161,467,918 (-)	NCBI		GRCr8
mRatBN7.2	1	152,046,515 - 152,056,675 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	1	152,046,517 - 152,056,725 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	1	160,033,373 - 160,043,515 (-)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	1	167,213,553 - 167,223,696 (-)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	1	160,087,040 - 160,097,182 (-)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	1	162,703,394 - 162,713,560 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	1	162,703,442 - 162,713,610 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	1	168,910,171 - 168,920,337 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	1	154,973,796 - 154,983,962 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	1	155,052,203 - 155,062,368 (-)	NCBI
Celera	1	150,140,146 - 150,150,299 (-)	NCBI		Celera
Cytogenetic Map	1	q32	NCBI

AQP11
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	9	78,522,280 - 78,547,456 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	11	79,570,672 - 79,595,844 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	11	72,653,721 - 72,673,698 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	11	76,295,778 - 76,315,292 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	11	76,295,778 - 76,315,292 (+)	Ensembl	panpan1.1		panPan2

AQP11
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	21	21,170,760 - 21,185,709 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	21	21,171,008 - 21,185,429 (-)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	21	21,062,597 - 21,077,580 (-)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	21	21,368,876 - 21,383,901 (-)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	21	21,367,271 - 21,383,947 (-)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	21	21,145,467 - 21,160,437 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	21	21,361,689 - 21,376,239 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	21	21,285,087 - 21,299,649 (-)	NCBI		UU_Cfam_GSD_1.0

Aqp11
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024404947	64,613,980 - 64,634,881 (+)	NCBI		HiC_Itri_2
SpeTri2.0	NW_004936498	6,213,583 - 6,237,273 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

AQP11
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	9	12,065,546 - 12,078,401 (+)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	9	12,065,550 - 12,076,339 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	9	13,217,315 - 13,228,258 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

AQP11
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	1	68,805,354 - 68,824,017 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	1	68,807,025 - 68,824,792 (+)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666043	56,947,167 - 56,965,056 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Aqp11
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624863	678,953 - 694,505 (+)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624863	679,049 - 694,765 (+)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Expression

Sequence

Nucleotide Sequences


RefSeq Transcripts	XM_005379835	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AGCD01015144	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AGCD01015145	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AGCD01015146	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	GBDF01161980	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

RefSeq Acc Id:

ENSCLAT00000024393 ⟹ ENSCLAP00000024160

Type:

CODING

Position:

Chinchilla Assembly	Chr	Position (strand)	Source
ChiLan1.0 Ensembl	NW_004955414	14,245,682 - 14,260,717 (-)	Ensembl

RefSeq Acc Id:

XM_005379835 ⟹ XP_005379892

Type:

CODING

Position:

Chinchilla Assembly	Chr	Position (strand)	Source
ChiLan1.0	NW_004955414	14,245,682 - 14,260,717 (-)	NCBI

Sequence:

show sequence

CCGCCGGCGCCCGGGCGTGAGGAGGCGGGGCCGCGGACTTGGGACTCCGGTCCGTTCGGCGCTT
CCCTGCGCGGGTGCGGGCGGCCGCACGCAGGAGCCATGTCCGCGCTGCCGCTGGCGGGGCTGCG
GCCCGAGGTGCGCGACAGCGGCACCTCGCTGGGGCTGATGTTGGCGGTCGTGCTGTGCATGGGG
CTGGCGCGCGCGATCGCGCGGAAGCAGCTGCACAGGCCCGCCGTCCACGCGTTTATCTTGGAGT
TTCTAGCCACCTTCCAGCTCTGCTGCTGCACCCACGAGCTGATGCTGCTGAGCGAGCAGGACTC
GGCGCACCCCACCTGGACGCTGACGCTCATCTACTTCTTCTCGTTGGTGCACGGTCTGACTCTG
GTGGGCACCTCCAGCAACCCGTGCGGGCTGATGGTGCAGATGATGCTGGGGGGGATGGCCCCCG
AGATGGGGGCGTTGAGGTTCTTGGCTCAGCTGGTGAGCGCCCTGTGCAGCAGGTACTGCATGCG
CGCCCTGTGGAGCCTGGGTCTGACTCAGTATCACTTCAGCGAGAGGATCTTCGCTTGCCAGAAT
CCTATCCACTCCGACTTGCCCAAGGCGGTTATTACAGAGGCCATCTGCTCCTTTATCTTCCACA
GCGCTCTGCTGCACTTCCAGGAGGTTCGAGCCAAGCTCCGCATCCACCTGCTGGCTGCACTCAT
CACCTTTTTGGCCTACGCAGGAGGAGGTCTGACGGGAGCTCTGTTCAATCCAACTTTGGCACTC
TCACTTCACTTCATGTGTTTTGATGAAGCGTTCCCTCGGTTTTTTATAGTATACTGGCTGGCTC
CTTCTTTAGGTATACTGTTGATGATTTTGATGTTCAGCTTTTTCCTTCCATGGCTGCATAACAA
CCAAATAGTTAATAAAAAGGAATAACTATTCCAAAAGCTCAGACTGAGTTACAAGACAGTCACG
CTGGATATGATAAAGATTTTATTACCTCATACTCAAAATACTAGCTGCACTGGATTCATCAATG
TTTTAATTTCCACCGAGGAAGTTGTCTTAAAAGTTTTCATCATGGGACTTAGAAAATTACTATA
AAAAAGAGGAATTCTGTATTTCTCAGTTAAAACTTG

hide sequence

Protein Sequences


Protein RefSeqs	XP_005379892	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSCLAP00000024160
	ENSCLAP00000024160.1

RefSeq Acc Id:

XP_005379892 ⟸ XM_005379835

- UniProtKB:

A0A8C2W2D4 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MSALPLAGLRPEVRDSGTSLGLMLAVVLCMGLARAIARKQLHRPAVHAFILEFLATFQLCCCTH
ELMLLSEQDSAHPTWTLTLIYFFSLVHGLTLVGTSSNPCGLMVQMMLGGMAPEMGALRFLAQLV
SALCSRYCMRALWSLGLTQYHFSERIFACQNPIHSDLPKAVITEAICSFIFHSALLHFQEVRAK
LRIHLLAALITFLAYAGGGLTGALFNPTLALSLHFMCFDEAFPRFFIVYWLAPSLGILLMILMF
SFFLPWLHNNQIVNKKE

hide sequence

RefSeq Acc Id:

ENSCLAP00000024160 ⟸ ENSCLAT00000024393

Additional Information

External Database Links

Database	Acc Id	Source(s)
Ensembl Genes	ENSCLAG00000016580	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSCLAT00000024393	ENTREZGENE
	ENSCLAT00000024393.1	UniProtKB/TrEMBL
Gene3D-CATH	1.20.1080.10	UniProtKB/TrEMBL
InterPro	Aquaporin-like	UniProtKB/TrEMBL
	Aquaporin_11	UniProtKB/TrEMBL
	Aquaporin_11/12	UniProtKB/TrEMBL
NCBI Gene	Aqp11	ENTREZGENE
PANTHER	AQUAPORIN	UniProtKB/TrEMBL
	PTHR21191:SF7	UniProtKB/TrEMBL
PIRSF	Aquaporin_11/12	UniProtKB/TrEMBL
PRINTS	AQUAPORIN11	UniProtKB/TrEMBL
Superfamily-SCOP	SSF81338	UniProtKB/TrEMBL
UniProt	A0A8C2W2D4	ENTREZGENE, UniProtKB/TrEMBL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

Send us a Message

Imported Disease Annotations - ClinVar