Afg1l (AFG1 like ATPase) - Rat Genome Database

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Gene: Afg1l (AFG1 like ATPase) Chinchilla lanigera
Analyze
Symbol: Afg1l
Name: AFG1 like ATPase
RGD ID: 9016077
Description: INVOLVED IN mitochondrial electron transport, cytochrome c to oxygen (ortholog); mitochondrial protein catabolic process (ortholog); mitochondrion organization (ortholog); ASSOCIATED WITH Charcot-Marie-Tooth disease type 4 (ortholog); genetic disease (ortholog); FOUND IN mitochondrial membrane (ortholog); mitochondrion (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: Lace1; lactation elevated 1; lactation elevated protein 1
RGD Orthologs
Human
Mouse
Rat
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: ChiLan1.0 - Chinchilla ChiLan1.0 Assembly
Position:
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541133,386,098 - 33,617,721 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495541133,386,568 - 33,617,721 (+)NCBIChiLan1.0ChiLan1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Transitive Annotation Pipeline Automated assignment of GO, PW and RDO ISO annotations across species
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Afg1l
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541133,386,098 - 33,617,721 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495541133,386,568 - 33,617,721 (+)NCBIChiLan1.0ChiLan1.0
AFG1L
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh386108,295,054 - 108,526,001 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl6108,294,991 - 108,526,796 (+)EnsemblGRCh38hg38GRCh38
GRCh376108,616,258 - 108,847,204 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 366108,722,791 - 108,950,951 (+)NCBINCBI36Build 36hg18NCBI36
Build 346108,722,790 - 108,950,958NCBI
Celera6109,362,234 - 109,590,401 (+)NCBICelera
Cytogenetic Map6q21NCBI
HuRef6106,183,791 - 106,411,846 (+)NCBIHuRef
CHM1_16108,879,055 - 109,107,208 (+)NCBICHM1_1
T2T-CHM13v2.06109,472,456 - 109,703,353 (+)NCBIT2T-CHM13v2.0
Afg1l
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391042,188,577 - 42,354,561 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1042,188,581 - 42,354,561 (-)EnsemblGRCm39 Ensembl
GRCm381042,312,581 - 42,478,565 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1042,312,585 - 42,478,565 (-)EnsemblGRCm38mm10GRCm38
MGSCv371042,032,391 - 42,198,371 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361042,001,000 - 42,166,829 (-)NCBIMGSCv36mm8
Celera1043,184,771 - 43,345,934 (-)NCBICelera
Cytogenetic Map10B2NCBI
cM Map1022.88NCBI
Afg1l
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr82047,380,582 - 47,550,307 (-)NCBIGRCr8
mRatBN7.22045,798,344 - 45,967,997 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl2045,798,349 - 45,967,906 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx2047,515,806 - 47,685,351 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.02047,165,974 - 47,335,507 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.02047,861,988 - 48,028,311 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.02047,038,824 - 47,208,812 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.02048,714,679 - 48,877,546 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.42046,296,402 - 46,302,522 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera2054,003,540 - 54,168,475 (+)NCBICelera
Cytogenetic Map20q13NCBI
AFG1L
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v25128,302,910 - 128,540,479 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan16126,189,125 - 126,428,316 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v06106,097,263 - 106,326,453 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.16109,956,704 - 110,370,685 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl6109,956,916 - 110,367,328 (+)Ensemblpanpan1.1panPan2
AFG1L
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11265,312,922 - 65,516,207 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1265,313,140 - 65,515,992 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1265,128,524 - 65,331,934 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01266,188,670 - 66,394,685 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1266,188,865 - 66,394,683 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11265,543,778 - 65,745,622 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01265,390,373 - 65,593,720 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01265,663,309 - 65,865,515 (+)NCBIUU_Cfam_GSD_1.0
Afg1l
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024404946100,278,885 - 100,479,172 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365644,553,732 - 4,757,616 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365644,553,758 - 4,755,126 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
AFG1L
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl174,367,617 - 74,591,853 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1174,367,421 - 74,590,766 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2183,635,078 - 83,849,079 (+)NCBISscrofa10.2Sscrofa10.2susScr3
AFG1L
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11365,341,306 - 65,559,829 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1365,331,879 - 65,531,108 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604037,659,385 - 37,885,317 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Afg1l
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462478013,771,341 - 14,038,146 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462478013,769,419 - 14,031,477 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts XM_005377845 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_005377846 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_013510900 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AGCD01012355 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AGCD01012356 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AGCD01012357 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AGCD01012358 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AGCD01012359 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AGCD01012360 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AGCD01012361 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AGCD01012362 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AGCD01012363 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AGCD01012364 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AGCD01012365 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AGCD01012366 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AGCD01012367 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AGCD01012368 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AGCD01012369 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AGCD01012370 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AGCD01012371 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AGCD01012372 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AGCD01012373 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  GBDF01055437 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSCLAT00000018561   ⟹   ENSCLAP00000018381
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_00495541133,386,098 - 33,617,721 (+)Ensembl
RefSeq Acc Id: XM_005377845   ⟹   XP_005377902
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_00495541133,386,568 - 33,617,721 (+)NCBI
Sequence:
RefSeq Acc Id: XM_005377846   ⟹   XP_005377903
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_00495541133,386,568 - 33,617,721 (+)NCBI
Sequence:
RefSeq Acc Id: XM_013510900   ⟹   XP_013366354
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_00495541133,397,505 - 33,617,721 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_005377902 (Get FASTA)   NCBI Sequence Viewer  
  XP_005377903 (Get FASTA)   NCBI Sequence Viewer  
  XP_013366354 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSCLAP00000018381
  ENSCLAP00000018381.1
Reference Protein Sequences
RefSeq Acc Id: XP_005377902   ⟸   XM_005377845
- Peptide Label: isoform X1
- UniProtKB: A0A8C2VR18 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_005377903   ⟸   XM_005377846
- Peptide Label: isoform X3
- Sequence:
RefSeq Acc Id: XP_013366354   ⟸   XM_013510900
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: ENSCLAP00000018381   ⟸   ENSCLAT00000018561


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCLAG00000012599 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCLAT00000018561 ENTREZGENE
  ENSCLAT00000018561.1 UniProtKB/TrEMBL
Gene3D-CATH 3.40.50.300 UniProtKB/TrEMBL
InterPro ATPase_AFG1-like UniProtKB/TrEMBL
  P-loop_NTPase UniProtKB/TrEMBL
NCBI Gene Lace1 ENTREZGENE
PANTHER AFG1-LIKE ATPASE UniProtKB/TrEMBL
  PTHR12169 UniProtKB/TrEMBL
Pfam AFG1_ATPase UniProtKB/TrEMBL
Superfamily-SCOP SSF52540 UniProtKB/TrEMBL
UniProt A0A8C2VR18 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2017-04-11 Afg1l  AFG1 like ATPase  Lace1  lactation elevated 1  Symbol and/or name change 5135510 APPROVED