Csta (cystatin A) - Rat Genome Database

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Gene: Csta (cystatin A) Chinchilla lanigera
Analyze
Symbol: Csta
Name: cystatin A
RGD ID: 9015132
Description: ENCODES a protein that exhibits cysteine-type endopeptidase inhibitor activity (ortholog); protease binding (ortholog); INVOLVED IN cell-cell adhesion (ortholog); keratinocyte differentiation (ortholog); negative regulation of proteolysis (ortholog); ASSOCIATED WITH alkaptonuria (ortholog); Disease Progression (ortholog); familial hypocalciuric hypercalcemia (ortholog); FOUND IN cornified envelope (ortholog); cytoplasm (ortholog); cytosol (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: cystatin A (stefin A); cystatin-A
RGD Orthologs
Human
Mouse
Rat
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: ChiLan1.0 - Chinchilla ChiLan1.0 Assembly
Position:
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495542721,617,054 - 21,630,773 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495542721,617,099 - 21,630,712 (+)NCBIChiLan1.0ChiLan1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Transitive Annotation Pipeline Automated assignment of GO, PW and RDO ISO annotations across species
2. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Csta
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495542721,617,054 - 21,630,773 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495542721,617,099 - 21,630,712 (+)NCBIChiLan1.0ChiLan1.0
CSTA
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh383122,325,248 - 122,341,969 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl3122,325,248 - 122,341,969 (+)EnsemblGRCh38hg38GRCh38
GRCh373122,044,095 - 122,060,816 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 363123,526,701 - 123,543,506 (+)NCBINCBI36Build 36hg18NCBI36
Build 343123,526,772 - 123,543,201NCBI
Celera3120,453,644 - 120,470,444 (+)NCBICelera
Cytogenetic Map3q21.1NCBI
HuRef3119,417,505 - 119,434,132 (+)NCBIHuRef
CHM1_13122,007,529 - 122,024,338 (+)NCBICHM1_1
T2T-CHM13v2.03125,044,823 - 125,061,527 (+)NCBIT2T-CHM13v2.0
Csta1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391635,940,316 - 35,951,559 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1635,940,316 - 35,951,611 (-)EnsemblGRCm39 Ensembl
GRCm381636,119,946 - 36,131,189 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1636,119,946 - 36,131,241 (-)EnsemblGRCm38mm10GRCm38
MGSCv371636,120,032 - 36,131,275 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361636,039,245 - 36,050,490 (-)NCBIMGSCv36mm8
Celera1636,603,771 - 36,614,988 (-)NCBICelera
Cytogenetic Map16B3NCBI
cM Map1625.43NCBI
Csta
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81178,125,813 - 78,136,818 (+)NCBIGRCr8
mRatBN7.21164,620,483 - 64,631,488 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1164,620,483 - 64,631,488 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1173,445,448 - 73,456,477 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01166,107,709 - 66,118,738 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01165,138,957 - 65,149,986 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01167,555,792 - 67,566,980 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1167,555,658 - 67,566,972 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01170,643,269 - 70,654,457 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41166,456,248 - 66,467,253 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11166,513,871 - 66,524,843 (+)NCBI
Celera1164,089,125 - 64,100,127 (+)NCBICelera
Cytogenetic Map11q22NCBI
CSTA
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22120,272,207 - 120,288,775 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan13120,277,158 - 120,293,554 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v03119,417,489 - 119,432,244 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.13126,323,901 - 126,338,133 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl3126,323,901 - 126,338,430 (+)Ensemblpanpan1.1panPan2
CSTA
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13325,477,789 - 25,489,123 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl3325,478,055 - 25,489,121 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha3325,502,665 - 25,513,886 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.03325,713,544 - 25,724,803 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl3325,713,699 - 25,724,801 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.13325,510,851 - 25,522,081 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.03325,553,550 - 25,564,806 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.03326,111,536 - 26,122,737 (+)NCBIUU_Cfam_GSD_1.0
Csta
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405602128,859,510 - 128,871,979 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365368,649,703 - 8,662,490 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365368,649,890 - 8,662,472 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
LOC396867
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl13138,181,723 - 138,236,860 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.113138,216,027 - 138,226,397 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.213147,854,121 - 147,859,830 (-)NCBISscrofa10.2Sscrofa10.2susScr3
CSTA
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12258,519,085 - 58,536,163 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2258,519,085 - 58,536,339 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666041107,806,784 - 107,823,308 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Csta
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_004624912657,774 - 671,329 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_004624912657,771 - 671,304 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSCLAT00000018051   ⟹   ENSCLAP00000017873
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_00495542721,617,054 - 21,630,773 (+)Ensembl
RefSeq Acc Id: XM_005386507   ⟹   XP_005386564
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_00495542721,617,099 - 21,630,712 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_005386564 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSCLAP00000017873
  ENSCLAP00000017873.1
Reference Protein Sequences
RefSeq Acc Id: XP_005386564   ⟸   XM_005386507
- UniProtKB: A0A8C2YRG1 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSCLAP00000017873   ⟸   ENSCLAT00000018051
Protein Domains
Cystatin


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCLAG00000012262 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCLAT00000018051 ENTREZGENE
  ENSCLAT00000018051.1 UniProtKB/TrEMBL
Gene3D-CATH 3.10.450.10 UniProtKB/TrEMBL
InterPro Cystatin_dom UniProtKB/TrEMBL
  Cystatin_sf UniProtKB/TrEMBL
  Prot_inh_cystat_CS UniProtKB/TrEMBL
  Prot_inh_stefin UniProtKB/TrEMBL
NCBI Gene Csta ENTREZGENE
PANTHER CYSTATIN-A UniProtKB/TrEMBL
  PTHR11414 UniProtKB/TrEMBL
Pfam Cystatin UniProtKB/TrEMBL
PRINTS STEFINA UniProtKB/TrEMBL
PROSITE CYSTATIN UniProtKB/TrEMBL
SMART SM00043 UniProtKB/TrEMBL
Superfamily-SCOP SSF54403 UniProtKB/TrEMBL
UniProt A0A8C2YRG1 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-08-16 Csta  cystatin A    cystatin A (stefin A)  Symbol and/or name change 5135510 APPROVED