Arl8a (ADP ribosylation factor like GTPase 8A)

Gene: Arl8a (ADP ribosylation factor like GTPase 8A) Chinchilla lanigera

Analyze

Symbol:

Arl8a

Name:

ADP ribosylation factor like GTPase 8A

RGD ID:

9013909

Description:

ENCODES a protein that exhibits GTP binding (ortholog); INVOLVED IN anterograde axonal transport (ortholog); ASSOCIATED WITH Experimental Liver Cirrhosis (ortholog); familial adult myoclonic epilepsy 5 (ortholog); gastrointestinal stromal tumor (ortholog); FOUND IN cytoplasm (ortholog); midbody (ortholog); spindle midzone (ortholog)

Type:

protein-coding

RefSeq Status:

MODEL

Previously known as:

ADP-ribosylation factor-like 8A; ADP-ribosylation factor-like protein 8A

RGD Orthologs

Alliance Genes

More Info

more info ...

Latest Assembly:

ChiLan1.0 - Chinchilla ChiLan1.0 Assembly

NCBI Annotation Information:

Annotation category: partial on reference assembly

Position:

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955406	38,224,124 - 38,226,542 (-)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955406	38,223,115 - 38,226,563 (-)	NCBI	ChiLan1.0	ChiLan1.0

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

Experimental Liver Cirrhosis (ISO)

familial adult myoclonic epilepsy 5 (ISO)

gastrointestinal stromal tumor (ISO)

genetic disease (ISO)

Hypokalemic Periodic Paralysis, Type 1 (ISO)

parathyroid carcinoma (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

anterograde axonal transport (ISO)

Cellular Component

cytoplasm (ISO)

midbody (ISO)

spindle midzone (ISO)

Molecular Function

GTP binding (ISO)

protein binding (ISO)

References

References - curated

#	Reference Title	Reference Citation
1.	Transitive Annotation Pipeline	Automated assignment of GO, PW and RDO ISO annotations across species

Additional References at PubMed

PMID:22301074	PMID:30032202

Genomics

Comparative Map Data

Arl8a
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955406	38,224,124 - 38,226,542 (-)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955406	38,223,115 - 38,226,563 (-)	NCBI	ChiLan1.0	ChiLan1.0

ARL8A
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	1	202,133,404 - 202,144,737 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	1	202,133,404 - 202,144,743 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	1	202,102,532 - 202,113,865 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	1	200,368,600 - 200,380,489 (-)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	1	198,833,633 - 198,845,523	NCBI
Celera	1	175,225,835 - 175,237,724 (-)	NCBI		Celera
Cytogenetic Map	1	q32.1	NCBI
HuRef	1	173,268,070 - 173,279,422 (-)	NCBI		HuRef
CHM1_1	1	203,524,823 - 203,536,155 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	1	201,390,975 - 201,402,296 (-)	NCBI		T2T-CHM13v2.0

Arl8a
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	1	135,074,572 - 135,084,007 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	1	135,074,562 - 135,084,007 (+)	Ensembl		GRCm39 Ensembl
GRCm38	1	135,146,834 - 135,156,268 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	1	135,146,824 - 135,156,269 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	1	137,043,411 - 137,052,845 (+)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	1	136,963,245 - 136,972,679 (+)	NCBI		MGSCv36	mm8
Celera	1	137,773,693 - 137,783,013 (+)	NCBI		Celera
Cytogenetic Map	1	E4	NCBI

Arl8a
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	13	49,137,632 - 49,146,633 (+)	NCBI		GRCr8
mRatBN7.2	13	46,585,845 - 46,594,851 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	13	46,585,845 - 46,594,851 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	13	49,192,596 - 49,201,567 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	13	50,480,668 - 50,489,635 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	13	47,746,744 - 47,755,694 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	13	51,972,974 - 51,981,976 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	13	51,972,974 - 51,981,976 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	13	57,024,684 - 57,033,686 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	13	48,108,242 - 48,117,244 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
Celera	13	46,911,113 - 46,920,108 (+)	NCBI		Celera
Cytogenetic Map	13	q13	NCBI

ARL8A
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	1	47,237,090 - 47,248,414 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	1	47,201,781 - 47,213,092 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	1	177,731,381 - 177,742,688 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	1	182,033,376 - 182,045,145 (-)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	1	182,033,376 - 182,045,145 (-)	Ensembl	panpan1.1		panPan2

ARL8A
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	7	875,679 - 877,184 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
Dog10K_Boxer_Tasha	7	922,825 - 931,231 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	7	878,512 - 887,030 (+)	NCBI		ROS_Cfam_1.0
UMICH_Zoey_3.1	7	866,867 - 875,258 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	7	975,161 - 983,495 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	7	999,160 - 1,007,493 (+)	NCBI		UU_Cfam_GSD_1.0

Arl8a
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024409344	73,160,437 - 73,170,294 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936567	2,395,111 - 2,404,972 (+)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936567	2,395,098 - 2,404,974 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

ARL8A
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	10	24,314,932 - 24,324,228 (-)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	10	24,314,929 - 24,324,225 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	10	28,715,516 - 28,718,510 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

ARL8A
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	25	27,261,506 - 27,272,477 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	25	27,261,562 - 27,271,416 (+)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666055	28,041,575 - 28,052,548 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Arl8a
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624807	8,593,619 - 8,602,647 (+)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624807	8,594,097 - 8,602,640 (+)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Expression

Sequence

Nucleotide Sequences


RefSeq Transcripts	XM_005375476	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AGCD01006597	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	GBCE01096074	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	GBDF01193465	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

RefSeq Acc Id:

ENSCLAT00000016773 ⟹ ENSCLAP00000016609

Type:

CODING

Position:

Chinchilla Assembly	Chr	Position (strand)	Source
ChiLan1.0 Ensembl	NW_004955406	38,224,124 - 38,226,542 (-)	Ensembl

RefSeq Acc Id:

XM_005375476 ⟹ XP_005375533

Type:

CODING

Position:

Chinchilla Assembly	Chr	Position (strand)	Source
ChiLan1.0	NW_004955406	38,223,115 - 38,226,563 (-)	NCBI

Sequence:

show sequence

GCAGGACTCGGCCCGGCCCGCGGGAGGGCGCGGCGGCAGCAGCGGCGGCGGGGGAGGAGGAGGA
GGGCGCTGAAGCCACACCCATCGGCGAGCGGATCCGGGGCCAGCGAGTCGTCGGCCGCCGCGCT
CGAGCCTCCGCCCGCACCGAGCCGCGGGACCCGGGCCGCACCGGGGAGGGGCCGCTCCGGGCCG
CAGCGCGAGGGCAGCGAGGGACGGCGGGGACCCGGCACCGGGCGGAGCCGGCGGCAGCGACCAT
GATCGCTTTGTTCAACAAGCTGCTGGACTGGTTCAAGGCCCTGTTCTGGAAGGAGGAGATGGAG
CTCACGCTGGTCGGGCTGCAGTACTCCGGCAAGACCACCTTCGTCAACGTGATCGCGTCAGGAC
AGTTCAATGAGGACATGATCCCCACAGTGGGCTTCAACATGCGCAAAATCACCAAAGGGAACGT
GACCATCAAGCTCTGGGATATTGGGGGACAGCCCCGATTCCGCAGCATGTGGGAGCGCTACTGC
CGAGGAGTGAGCGCCATCGTGTACATGGTGGACGCTGCTGACCAGGAGAAGATCGAGGCCTCCA
AGAACGAGCTGCACAACCTGCTCGACAAGCCTCAGCTGCAGGGCATCCCGGTCTTAGTCCTGGG
CAACAAGCGAGACCTCCCCGGAGCTCTGGATGAGAAGGAGTTGATTGAGAAAATGAATCTGTCT
GCCATCCAGGACCGAGAGATCTGCTGCTATTCCATCTCCTGCAAAGAGAAGGACAACATTGACA
TCACCCTACAGTGGCTTATTCAGCACTCAAAGTCGCGGAGAAGCTGAGACGGCGGTCCTTCTCC
CTCACACCAGGGACCGTGGCCATGGAAACCTGAAGCCGAGCTCCCCGCCCGTCCTTTTGTCCCC
CTAAGCGCACCCCTCCTCACTCAGCGAGGGGAGGGCCCTGGGGCTCCCAGAGCCCCATTCTGCT
GAGGTTTGAACTCCTGTTTTTACTGTACAATAAATCGCCCCCCATCGGGCCTCCAGCCTCTCCC
CTGCCCCTCTCCAGGGGTCCCCTCGCCCAGCCGCTTCCCTCACCTGTCCACAGCCCCGGTGCCC
AGCCCTGGCCCCCTCGCTTCCCCCCTTCCCTTTTCAACTCTCTGTTATTGTCCTGTGTGTACAG
TATATATATGTATATATATTTTAATTTTTTAATTTAAGCAAAGACTAAAATCAACCATTTGATG
CTGCAGGGGCCATTCAGGATCTGGGAGGGGGCAGTCTGGAGAGAGGGAAAGAGATGCAGGGTTG
GCTGGGCAAGTTCACATCTGGAGAGACGAGGCTGGCGCGTGGGGCAGGTGCCAGCCTGGGCACT
GGTGCCGCCCCCTGTCCTGTGTGTCTCTGCCTCCCGCTCTGGCCTGTCTCTGCACGCCACAGGC
TGGTGGGAGCCTAGGTAGGCACCTCCTCTCTGTCCCCAGCCTTGGTAGGGCCACCAGGCACCAC
CAGGTGCCAGAGATCACCAGGCCTAGGGGCCGGAAGCTGGCGTCCATGCTGCCCCAGCGCCCGA
CACCTGTTCCCGGCCCCCAGCTCCTGCCCCACCAGGGCCCCCACCTCCATGGCCCACCTCATTT
TCTGTTCTCATTTTGCAGAGTTGCACAAGGAGAGAACTCAGCATGGGGGGTTGGTTCTTTGGAT
TTTGTTTTTGGTTGTTTTATTTGTTTAATGATTTGTAAAGTGATGTTCCTCTTCCTTTTTTACA
CTTTTCACTCATATTTAACCTCTGTTTGGAAAATGATTCTTGTAACTGTACATTTTTTTGCCTT
CTAATAACAATAAATTTCCAATTTTGTGTTGA

hide sequence

Protein Sequences


Protein RefSeqs	XP_005375533	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSCLAP00000016609.1

RefSeq Acc Id:	XP_005375533 ⟸ XM_005375476
- Sequence:	show sequence MIALFNKLLDWFKALFWKEEMELTLVGLQYSGKTTFVNVIASGQFNEDMIPTVGFNMRKITKGN VTIKLWDIGGQPRFRSMWERYCRGVSAIVYMVDAADQEKIEASKNELHNLLDKPQLQGIPVLVL GNKRDLPGALDEKELIEKMNLSAIQDREICCYSISCKEKDNIDITLQWLIQHSKSRRS hide sequence

RefSeq Acc Id:

ENSCLAP00000016609 ⟸ ENSCLAT00000016773

Additional Information

External Database Links

Database	Acc Id	Source(s)
Ensembl Genes	ENSCLAG00000011411	Ensembl, UniProtKB/TrEMBL
Ensembl Transcript	ENSCLAT00000016773.1	UniProtKB/TrEMBL
Gene3D-CATH	3.40.50.300	UniProtKB/TrEMBL
InterPro	Arl8a/8b	UniProtKB/TrEMBL
	P-loop_NTPase	UniProtKB/TrEMBL
	Small_GTPase_ARF/SAR	UniProtKB/TrEMBL
NCBI Gene	Arl8a	ENTREZGENE
PANTHER	ADP-RIBOSYLATION FACTOR-LIKE PROTEIN 8	UniProtKB/TrEMBL
	ADP-RIBOSYLATION FACTOR-LIKE PROTEIN 8A	UniProtKB/TrEMBL
Pfam	Arf	UniProtKB/TrEMBL
PRINTS	SAR1GTPBP	UniProtKB/TrEMBL
PROSITE	ARF	UniProtKB/TrEMBL
Superfamily-SCOP	SSF52540	UniProtKB/TrEMBL
UniProt	A0A8C2VJL9_CHILA	UniProtKB/TrEMBL

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2016-08-16	Arl8a	ADP ribosylation factor like GTPase 8A		ADP-ribosylation factor-like 8A	Symbol and/or name change	5135510	APPROVED

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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Imported Disease Annotations - CTD

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Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD