Efemp2 (EGF containing fibulin extracellular matrix protein 2) - Rat Genome Database

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Gene: Efemp2 (EGF containing fibulin extracellular matrix protein 2) Chinchilla lanigera
Analyze
Symbol: Efemp2
Name: EGF containing fibulin extracellular matrix protein 2
RGD ID: 9013676
Description: ENCODES a protein that exhibits heparin binding (ortholog); protein homodimerization activity (ortholog); INVOLVED IN aorta development (ortholog); aorta smooth muscle tissue morphogenesis (ortholog); artery development (ortholog); ASSOCIATED WITH aortic aneurysm (ortholog); aortic dissection (ortholog); arterial tortuosity syndrome (ortholog); FOUND IN basement membrane (ortholog); elastic fiber (ortholog); extracellular matrix (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: EGF containing fibulin like extracellular matrix protein 2; EGF containing fibulin-like extracellular matrix protein 2; EGF-containing fibulin-like extracellular matrix protein 2
RGD Orthologs
Human
Mouse
Rat
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: ChiLan1.0 - Chinchilla ChiLan1.0 Assembly
Position:
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495542219,463,987 - 19,470,605 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495542219,463,090 - 19,470,605 (+)NCBIChiLan1.0ChiLan1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


References

References - curated
# Reference Title Reference Citation
1. Transitive Annotation Pipeline Automated assignment of GO, PW and RDO ISS annotations to Chinchilla, Squirrel, Bonobo and/or Dog genes from Human gene annotations
2. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline

Genomics

Comparative Map Data
Efemp2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495542219,463,987 - 19,470,605 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495542219,463,090 - 19,470,605 (+)NCBIChiLan1.0ChiLan1.0
EFEMP2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381165,866,441 - 65,872,800 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p13 Ensembl1165,866,441 - 65,873,592 (-)EnsemblGRCh38hg38GRCh38
GRCh371165,633,912 - 65,640,271 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361165,390,488 - 65,396,852 (-)NCBINCBI36hg18NCBI36
Build 341165,390,494 - 65,396,793NCBI
Celera1162,957,818 - 62,964,246 (-)NCBI
Cytogenetic Map11q13.1NCBI
HuRef1161,960,429 - 61,966,923 (-)NCBIHuRef
CHM1_11165,518,326 - 65,524,819 (-)NCBICHM1_1
T2T-CHM13v2.01165,860,912 - 65,867,272 (-)NCBI
Efemp2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39195,523,974 - 5,532,548 (+)NCBIGRCm39mm39
GRCm39 Ensembl195,523,982 - 5,532,545 (+)Ensembl
GRCm38195,473,946 - 5,482,520 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl195,473,954 - 5,482,517 (+)EnsemblGRCm38mm10GRCm38
MGSCv37195,474,690 - 5,481,854 (+)NCBIGRCm37mm9NCBIm37
MGSCv36195,474,750 - 5,481,853 (+)NCBImm8
Celera195,346,431 - 5,353,554 (+)NCBICelera
Cytogenetic Map19ANCBI
Efemp2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21202,781,692 - 202,789,784 (+)NCBImRatBN7.2
mRatBN7.2 Ensembl1202,781,665 - 202,789,414 (+)Ensembl
Rnor_6.01220,853,695 - 220,861,420 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1220,854,403 - 220,861,420 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01227,783,038 - 227,790,741 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41208,118,537 - 208,125,490 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11208,271,989 - 208,278,942 (+)NCBI
Celera1200,318,443 - 200,324,890 (+)NCBICelera
Cytogenetic Map1q43NCBI
EFEMP2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.11164,555,877 - 64,561,950 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1164,555,877 - 64,561,950 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v01161,226,755 - 61,233,181 (-)NCBIMhudiblu_PPA_v0panPan3
EFEMP2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11851,389,797 - 51,396,109 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1851,389,824 - 51,396,107 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1849,997,510 - 50,004,619 (+)NCBI
ROS_Cfam_1.01852,427,071 - 52,434,176 (+)NCBI
ROS_Cfam_1.0 Ensembl1852,427,841 - 52,434,176 (+)Ensembl
UMICH_Zoey_3.11851,527,128 - 51,534,242 (+)NCBI
UNSW_CanFamBas_1.01851,101,501 - 51,108,618 (+)NCBI
UU_Cfam_GSD_1.01851,890,821 - 51,897,925 (+)NCBI
Efemp2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_0244049477,221,048 - 7,228,320 (+)NCBI
SpeTri2.0NW_0049365993,663,288 - 3,670,048 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
EFEMP2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl26,450,332 - 6,463,486 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.126,455,155 - 6,463,493 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.225,559,189 - 5,567,521 (+)NCBISscrofa10.2Sscrofa10.2susScr3
EFEMP2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.118,384,212 - 8,391,501 (+)NCBIChlSab1.1chlSab2
ChlSab1.1 Ensembl18,385,020 - 8,390,889 (+)EnsemblChlSab1.1chlSab2
Vero_WHO_p1.0NW_023666038105,673,390 - 105,680,538 (+)NCBIVero_WHO_p1.0
Efemp2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462476720,559,795 - 20,566,341 (+)EnsemblHetGla_female_1.0hetGla2
HetGla 1.0NW_00462476720,559,801 - 20,566,326 (+)NCBIHetGla_female_1.0hetGla2


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSCLAT00000023591   ⟹   ENSCLAP00000023370
RefSeq Status:
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_00495542219,463,987 - 19,470,605 (+)Ensembl
RefSeq Acc Id: ENSCLAT00000023592   ⟹   ENSCLAP00000023371
RefSeq Status:
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_00495542219,464,382 - 19,470,144 (+)Ensembl
RefSeq Acc Id: ENSCLAT00000023593   ⟹   ENSCLAP00000023372
RefSeq Status:
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_00495542219,464,382 - 19,470,144 (+)Ensembl
RefSeq Acc Id: ENSCLAT00000023594   ⟹   ENSCLAP00000023373
RefSeq Status:
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_00495542219,464,382 - 19,469,046 (+)Ensembl
RefSeq Acc Id: XM_005384452   ⟹   XP_005384509
RefSeq Status:
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_00495542219,463,090 - 19,470,605 (+)NCBI
Sequence:
RefSeq Acc Id: XM_005384453   ⟹   XP_005384510
RefSeq Status:
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_00495542219,463,987 - 19,470,605 (+)NCBI
Sequence:
RefSeq Acc Id: XM_005384454   ⟹   XP_005384511
RefSeq Status:
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_00495542219,464,133 - 19,470,605 (+)NCBI
Sequence:
RefSeq Acc Id: XM_013513845   ⟹   XP_013369299
RefSeq Status:
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_00495542219,463,372 - 19,470,605 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_005384509 (Get FASTA)   NCBI Sequence Viewer  
  XP_005384510 (Get FASTA)   NCBI Sequence Viewer  
  XP_005384511 (Get FASTA)   NCBI Sequence Viewer  
  XP_013369299 (Get FASTA)   NCBI Sequence Viewer  
Reference Sequences
RefSeq Acc Id: XP_005384509   ⟸   XM_005384452
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: XP_005384510   ⟸   XM_005384453
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_005384511   ⟸   XM_005384454
- Peptide Label: isoform X3
- Sequence:
RefSeq Acc Id: XP_013369299   ⟸   XM_013513845
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: ENSCLAP00000023370   ⟸   ENSCLAT00000023591
RefSeq Acc Id: ENSCLAP00000023371   ⟸   ENSCLAT00000023592
RefSeq Acc Id: ENSCLAP00000023372   ⟸   ENSCLAT00000023593
RefSeq Acc Id: ENSCLAP00000023373   ⟸   ENSCLAT00000023594
Protein Domains
EGF-like


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCLAG00000016031 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein ENSCLAP00000023370 ENTREZGENE, UniProtKB/TrEMBL
  ENSCLAP00000023371 UniProtKB/TrEMBL
  ENSCLAP00000023372 ENTREZGENE, UniProtKB/TrEMBL
  ENSCLAP00000023373 UniProtKB/TrEMBL
Ensembl Transcript ENSCLAT00000023591 ENTREZGENE, UniProtKB/TrEMBL
  ENSCLAT00000023592 UniProtKB/TrEMBL
  ENSCLAT00000023593 ENTREZGENE, UniProtKB/TrEMBL
  ENSCLAT00000023594 UniProtKB/TrEMBL
InterPro cEGF UniProtKB/TrEMBL
  Efemp2 UniProtKB/TrEMBL
  EGF-like_Ca-bd_dom UniProtKB/TrEMBL
  EGF-like_dom UniProtKB/TrEMBL
  EGF-type_Asp/Asn_hydroxyl_site UniProtKB/TrEMBL
  EGF_Ca-bd_CS UniProtKB/TrEMBL
  Growth_fac_rcpt_cys_sf UniProtKB/TrEMBL
NCBI Gene Efemp2 ENTREZGENE
PANTHER PTHR24034:SF96 UniProtKB/TrEMBL
Pfam cEGF UniProtKB/TrEMBL
  EGF_CA UniProtKB/TrEMBL
PROSITE ASX_HYDROXYL UniProtKB/TrEMBL
  EGF_2 UniProtKB/TrEMBL
  EGF_3 UniProtKB/TrEMBL
  EGF_CA UniProtKB/TrEMBL
SMART EGF UniProtKB/TrEMBL
  EGF_CA UniProtKB/TrEMBL
Superfamily-SCOP SSF57184 UniProtKB/TrEMBL
UniProt A0A8C2W0I6_CHILA UniProtKB/TrEMBL
  A0A8C2W109_CHILA UniProtKB/TrEMBL
  A0A8C2YU27_CHILA UniProtKB/TrEMBL
  A0A8C2YU34_CHILA UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2017-10-17 Efemp2  EGF containing fibulin extracellular matrix protein 2    EGF containing fibulin like extracellular matrix protein 2  Symbol and/or name change 5135510 APPROVED
2016-08-03 Efemp2  EGF containing fibulin like extracellular matrix protein 2    EGF containing fibulin-like extracellular matrix protein 2  Symbol and/or name change 5135510 APPROVED