Lpar2 (lysophosphatidic acid receptor 2)

Gene: Lpar2 (lysophosphatidic acid receptor 2) Chinchilla lanigera

Analyze

Symbol:

Lpar2

Name:

lysophosphatidic acid receptor 2

RGD ID:

9006420

Description:

ENCODES a protein that exhibits PDZ domain binding (ortholog); INVOLVED IN G protein-coupled receptor signaling pathway (ortholog); positive regulation of MAPK cascade (ortholog); positive regulation of Rho protein signal transduction (ortholog); ASSOCIATED WITH genetic disease (ortholog); FOUND IN cell surface (ortholog); endocytic vesicle (ortholog); glutamatergic synapse (ortholog)

Type:

protein-coding

RefSeq Status:

RGD Orthologs

Alliance Genes

More Info

more info ...

Latest Assembly:

ChiLan1.0 - Chinchilla ChiLan1.0 Assembly

Position:

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955524	2,390,598 - 2,394,877 (+)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955524	2,390,354 - 2,395,436 (+)	NCBI	ChiLan1.0	ChiLan1.0

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

genetic disease (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

G protein-coupled receptor signaling pathway (ISO)

positive regulation of MAPK cascade (ISO)

positive regulation of Rho protein signal transduction (ISO)

Cellular Component

cell surface (ISO)

endocytic vesicle (ISO)

glutamatergic synapse (ISO)

presynaptic active zone membrane (ISO)

Molecular Function

PDZ domain binding (ISO)

protein binding (ISO)

References

References - curated

#	Reference Title	Reference Citation
1.	Transitive Annotation Pipeline	Automated assignment of GO, PW and RDO ISO annotations across species

Additional References at PubMed

PMID:22301074

Genomics

Comparative Map Data

Lpar2
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955524	2,390,598 - 2,394,877 (+)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955524	2,390,354 - 2,395,436 (+)	NCBI	ChiLan1.0	ChiLan1.0

LPAR2
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	19	19,623,655 - 19,628,220 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	19	19,623,655 - 19,628,930 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	19	19,734,464 - 19,739,029 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	19	19,595,477 - 19,600,017 (-)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	19	19,595,476 - 19,600,017	NCBI
Celera	19	19,638,539 - 19,643,114 (-)	NCBI		Celera
Cytogenetic Map	19	p13.11	NCBI
HuRef	19	19,296,769 - 19,301,344 (-)	NCBI		HuRef
CHM1_1	19	19,735,551 - 19,740,126 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	19	19,761,164 - 19,765,730 (-)	NCBI		T2T-CHM13v2.0

Lpar2
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	8	70,275,215 - 70,283,752 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	8	70,275,079 - 70,283,752 (+)	Ensembl		GRCm39 Ensembl
GRCm38	8	69,822,565 - 69,831,102 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	8	69,822,429 - 69,831,102 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	8	72,346,464 - 72,355,001 (+)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	8	72,751,418 - 72,760,091 (+)	NCBI		MGSCv36	mm8
Celera	8	72,373,530 - 72,382,072 (+)	NCBI		Celera
Cytogenetic Map	8	B3.3	NCBI
cM Map	8	33.91	NCBI

Lpar2
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	16	19,625,974 - 19,633,905 (-)	NCBI		GRCr8
mRatBN7.2	16	19,592,067 - 19,599,998 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	16	19,595,655 - 19,599,998 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	16	19,633,944 - 19,641,804 (-)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	16	20,771,896 - 20,779,773 (-)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	16	19,686,925 - 19,694,785 (-)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	16	21,343,313 - 21,348,913 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	16	21,344,456 - 21,348,391 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	16	21,257,145 - 21,262,902 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	16	20,079,826 - 20,085,307 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
Celera	16	19,783,465 - 19,789,027 (-)	NCBI		Celera
Cytogenetic Map	16	p14	NCBI

LPAR2
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	20	24,484,829 - 24,489,696 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	19	23,491,289 - 23,496,154 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	19	19,060,927 - 19,065,792 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	19	20,057,179 - 20,062,171 (-)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	19	20,057,179 - 20,061,260 (-)	Ensembl	panpan1.1		panPan2

LPAR2
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	20	43,646,642 - 43,650,270 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	20	43,647,653 - 43,650,710 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	20	43,562,238 - 43,565,865 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	20	44,132,323 - 44,135,954 (+)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	20	44,133,607 - 44,136,385 (+)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	20	43,370,025 - 43,373,646 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	20	43,779,532 - 43,783,139 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	20	44,055,222 - 44,058,857 (+)	NCBI		UU_Cfam_GSD_1.0

Lpar2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024405118	202,323,008 - 202,326,916 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936596	1,872,862 - 1,878,402 (+)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936596	1,872,919 - 1,878,304 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

LPAR2
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	2	58,298,271 - 58,300,844 (+)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	2	58,296,381 - 58,300,869 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	2	58,395,164 - 58,399,454 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3
Pig Cytomap	2	q2.1	NCBI

LPAR2
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	6	18,082,907 - 18,088,240 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	6	18,082,784 - 18,087,145 (-)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666074	1,210,591 - 1,216,133 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Lpar2
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624908	2,349,477 - 2,357,633 (-)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624908	2,349,783 - 2,357,969 (-)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Expression

Sequence

Nucleotide Sequences


RefSeq Transcripts	XM_005409641	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AGCD01068814	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AGCD01068815	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AGCD01068816	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	GBCQ01014829	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

RefSeq Acc Id:

ENSCLAT00000024955 ⟹ ENSCLAP00000024717

Type:

CODING

Position:

Chinchilla Assembly	Chr	Position (strand)	Source
ChiLan1.0 Ensembl	NW_004955524	2,390,598 - 2,394,877 (+)	Ensembl

RefSeq Acc Id:

XM_005409641 ⟹ XP_005409698

Type:

CODING

Position:

Chinchilla Assembly	Chr	Position (strand)	Source
ChiLan1.0	NW_004955524	2,390,354 - 2,395,436 (+)	NCBI

Sequence:

show sequence

CGGGGCGGGTGCCGACGCGTCCTGCGGGCGCTCTCCGGGCTGAAAACCAAAGGGGCCATTGACC
CGGGGGCTCATTCATAAGTCCGCTTGGCAGATGAGCGCGCCCCACCCGCGCCCCGTGAGCCTGC
CCTTCCTGGGTCGGCTCCTCCGCCTGTCCCCTGCAGCCCAGCGGCCGCTGCCCGAAGCCCTTCC
CGGCCGCCCGCGCTGACCGCTGTCTCGTCTCCCTGCTCCCCAGACGGCCGCCATGGGCCAGTGC
CACTACAACGAGACGGTTGGCTTCTTCTACAACAACAGCGGCAAGGAGCTCAGCTCCCACTGGC
GCCCCAAGGATGTGGTGGTGGTGGCGCTGGGGCTGACCGTCAGCGTGCTGGTCCTCCTGACTAA
CCTGCTGGTCATCACGGCCATCGCCTCCAACCGCCGCTTCCACCAGCCCATCTACTACCTGCTT
GGCAACCTGGCGGCGGCCGACCTGTTCGCCGGCGTGGCCTACCTCTTCCTCATGTTCCACACCG
GCCCGCGCACGGCCAGGCTCTCGCTCCAGGGCTGGTTCCTGCGGCAGGGTCTGCTGGACACCAG
CCTGACGGCGTCCGTGGCCACCCTGCTGGCCATCGCGGTGGAGCGGCACCGCAGCGTGATGGCC
GTGCAGCTGCACAGCCGCCTGCCCCGCGGGCGCGTGGTCCTGCTCATCGTGGGCGTGTGGGTGG
CCGCCCTGGGCCTGGGGCTGCTGCCCGCCCACTCCTGGCACTGCCTGTGCGCCCTGGACCGTTG
CTCGCGCATGGCACCCCTGCTGAGCCGCACCTACCTGGCCGTGTGGGCCCTGTCCAGCCTGCTG
GTCTTCCTGCTCATGGTCGCGGTCTACACCCGCATTTTCTTCTACGTGCGGAGGCGAGTGCAGC
GCATGGCCGAGCACGTCAGCTGCCACCCCCGCTACCGAGAGACCACACTCAGCCTGGTCAAGAC
TGTGGTCATCATCCTGGGGGCCTTCGTGGTCTGCTGGACGCCGGGCCAGGTGGTGCTGCTTCTG
GACGGCCTGGACTGCAAGTCGTGCAACGTCCTGGCGGTGGAGAAGTACTTCCTGCTGTTGGCGG
AGGCCAACTCCCTGGTCAACGCGGCCGTGTACTCCTGCCGGGACGCCGAGATGCGCCGCACCTT
CCGCCGCCTGCTGTGCTGCCCGTGCCTGCGCCGCTCCGCCCGGGAGTCGGCCCGNNNNNNNNNN
NNNGCGCACACCGGCGCCAGCACGCGCCTCGAGCTCCCCGAGAACGGCCACGCGCTCCTGGACT
CCACCCTGTAGCCGCTGTCCACGCCAGCCGCACCCCGCTCGGCCTCCCCGCGCGCGCACTGCCA
GCCTGGGCTCCGCAACTGGGCGCCAGGAGAGTCGGGCGGGGTGCGGGAGTCTGGCTTTCTCACT
CATCTCAGGTTTTAAGGTCTTTTAACGGACGTTCTTTTTTTACGGTACATCCCGCTAACCGCTG
TAGACCAGTTCCTCCACGTGGTACTACGGCTGCTAAGGGTAGGAGACGTGAGGACTGGCTGGGG
CACCCTTGTCATCCCAGCACTCAGGAGGCTGAGGCAGGAGGCTCGCAGTGATCTCAAGGCCAGC
CTGGGCTACACAGGGAGACCCTGTCTCAAAAGACAAAAAAGAGAAAAAGAGATGAATGCGGGGC
CTCCTGGTCCACCTGCCCACTGTGACAGAAGACCCGGTGGCCCGAGGGAGTGCTGCGTCCCTGC
GACTGACACACCAAGGGGGCTGCGTGTGAGCCGCGGAGGCTCGGGCGGGTTGCAGCCTGCAGGG
TGGCCTGGGGGCCCCAGGGAAGGTGTAATACAGGAAGTAAACGTTTCCACTCTGA

hide sequence

Protein Sequences


Protein RefSeqs	XP_005409698	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSCLAP00000024717.1

RefSeq Acc Id:

XP_005409698 ⟸ XM_005409641

- UniProtKB:

A0A8C2W3N3 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MGQCHYNETVGFFYNNSGKELSSHWRPKDVVVVALGLTVSVLVLLTNLLVITAIASNRRFHQPI
YYLLGNLAAADLFAGVAYLFLMFHTGPRTARLSLQGWFLRQGLLDTSLTASVATLLAIAVERHR
SVMAVQLHSRLPRGRVVLLIVGVWVAALGLGLLPAHSWHCLCALDRCSRMAPLLSRTYLAVWAL
SSLLVFLLMVAVYTRIFFYVRRRVQRMAEHVSCHPRYRETTLSLVKTVVIILGAFVVCWTPGQV
VLLLDGLDCKSCNVLAVEKYFLLLAEANSLVNAAVYSCRDAEMRRTFRRLLCCPCLRRSARESA
RXXXXAHTGASTRLELPENGHALLDSTL

hide sequence

RefSeq Acc Id:

ENSCLAP00000024717 ⟸ ENSCLAT00000024955

Protein Domains

G-protein coupled receptors family 1 profile

Additional Information

External Database Links

Database	Acc Id	Source(s)
Ensembl Genes	ENSCLAG00000016969	Ensembl, UniProtKB/TrEMBL
Ensembl Transcript	ENSCLAT00000024955.1	UniProtKB/TrEMBL
Gene3D-CATH	Rhodopsin 7-helix transmembrane proteins	UniProtKB/TrEMBL
InterPro	GPCR_Rhodpsn	UniProtKB/TrEMBL
	GPCR_Rhodpsn_7TM	UniProtKB/TrEMBL
	LPA_rcpt	UniProtKB/TrEMBL
	LPA_rcpt_EDG4	UniProtKB/TrEMBL
NCBI Gene	Lpar2	ENTREZGENE
PANTHER	G-PROTEIN COUPLED RECEPTOR	UniProtKB/TrEMBL
	LYSOPHOSPHATIDIC ACID RECEPTOR 2	UniProtKB/TrEMBL
Pfam	7tm_1	UniProtKB/TrEMBL
PRINTS	EDG4RECEPTOR	UniProtKB/TrEMBL
	GPCRRHODOPSN	UniProtKB/TrEMBL
	LPARECEPTOR	UniProtKB/TrEMBL
PROSITE	G_PROTEIN_RECEP_F1_1	UniProtKB/TrEMBL
	G_PROTEIN_RECEP_F1_2	UniProtKB/TrEMBL
SMART	7TM_GPCR_Srsx	UniProtKB/TrEMBL
Superfamily-SCOP	Family A G protein-coupled receptor-like	UniProtKB/TrEMBL
UniProt	A0A8C2W3N3	ENTREZGENE, UniProtKB/TrEMBL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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