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Gene: Hmgcl (3-hydroxy-3-methylglutaryl-CoA lyase) Chinchilla lanigera
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Symbol: Hmgcl
Name: 3-hydroxy-3-methylglutaryl-CoA lyase
RGD ID: 9004045
Description: ENCODES a protein that exhibits carboxylic acid binding (ortholog); fatty-acyl-CoA binding (ortholog); hydroxymethylglutaryl-CoA lyase activity (ortholog); INVOLVED IN acyl-CoA metabolic process (ortholog); ketone body biosynthetic process (ortholog); lipid metabolic process (ortholog); PARTICIPATES IN 3-hydroxy-3-methylglutaryl-CoA lyase deficiency pathway; 3-hydroxyisobutyric aciduria pathway; 3-methylcrotonyl CoA carboxylase 1 deficiency pathway; ASSOCIATED WITH 3-Hydroxy-3-Methylglutaryl-CoA Lyase Deficiency (ortholog); amino acid metabolic disorder (ortholog); Developmental Disabilities (ortholog); FOUND IN peroxisome (ortholog); protein-containing complex (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Also known as: 3-hydroxymethyl-3-methylglutaryl-CoA lyase; hydroxymethylglutaryl-CoA lyase, mitochondrial
Orthologs:
Homo sapiens (human) : HMGCL (3-hydroxy-3-methylglutaryl-CoA lyase)  HGNC  Alliance
Mus musculus (house mouse) : Hmgcl (3-hydroxy-3-methylglutaryl-Coenzyme A lyase)  MGI  Alliance
Rattus norvegicus (Norway rat) : Hmgcl (3-hydroxy-3-methylglutaryl-CoA lyase)  Alliance
Pan paniscus (bonobo/pygmy chimpanzee) : HMGCL (3-hydroxy-3-methylglutaryl-CoA lyase)
Canis lupus familiaris (dog) : HMGCL (3-hydroxy-3-methylglutaryl-CoA lyase)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Hmgcl (3-hydroxy-3-methylglutaryl-CoA lyase)
Sus scrofa (pig) : HMGCL (3-hydroxy-3-methylglutaryl-CoA lyase)
Chlorocebus sabaeus (African green monkey) : HMGCL (3-hydroxy-3-methylglutaryl-CoA lyase)
Heterocephalus glaber (naked mole-rat) : Hmgcl (3-hydroxy-3-methylglutaryl-CoA lyase)
more info ...
Latest Assembly: ChiLan1.0 - Chinchilla ChiLan1.0 Assembly
Position:
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554523,720,103 - 3,735,192 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554523,720,103 - 3,734,730 (-)NCBIChiLan1.0ChiLan1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated

Genomics

Comparative Map Data

Expression


Sequence

Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
Nomenclature History
 
More on Hmgcl
NCBI Gene
Ensembl Gene
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 9004045
Created: 2014-08-14
Species: Chinchilla lanigera
Last Modified: 2019-11-26
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.