Fgf8 (fibroblast growth factor 8) - Rat Genome Database

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Gene: Fgf8 (fibroblast growth factor 8) Chinchilla lanigera
Analyze
Symbol: Fgf8
Name: fibroblast growth factor 8
RGD ID: 9004013
Description: ENCODES a protein that exhibits chemoattractant activity (ortholog); growth factor activity (ortholog); type 1 fibroblast growth factor receptor binding (ortholog); INVOLVED IN aorta morphogenesis (ortholog); blood vessel remodeling (ortholog); bone development (ortholog); PARTICIPATES IN fibroblast growth factor signaling pathway; ASSOCIATED WITH 22q11 Deletion Syndrome (ortholog); breast cancer (ortholog); Cardiovascular Abnormalities (ortholog); FOUND IN external side of plasma membrane (ortholog); extracellular space (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Also known as: fibroblast growth factor 8 (androgen-induced)
RGD Orthologs
Human
Mouse
Rat
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: ChiLan1.0 - Chinchilla ChiLan1.0 Assembly
Position:
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554858,517,412 - 8,521,770 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554858,517,412 - 8,521,732 (+)NCBIChiLan1.0ChiLan1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process
aorta morphogenesis  (ISO)
blood vessel remodeling  (ISO)
bone development  (ISO)
branching involved in blood vessel morphogenesis  (ISO)
branching involved in salivary gland morphogenesis  (ISO)
branching involved in ureteric bud morphogenesis  (ISO)
cell fate commitment  (ISO)
cell migration involved in mesendoderm migration  (ISO)
cell proliferation in forebrain  (ISO)
central nervous system neuron development  (ISO)
corticotropin hormone secreting cell differentiation  (ISO)
determination of left/right symmetry  (ISO)
dopaminergic neuron differentiation  (ISO)
dorsal/ventral axon guidance  (ISO)
embryo development ending in birth or egg hatching  (ISO)
embryonic heart tube development  (ISO)
embryonic hindlimb morphogenesis  (ISO)
embryonic neurocranium morphogenesis  (ISO)
epithelial to mesenchymal transition involved in endocardial cushion formation  (ISO)
fibroblast growth factor receptor signaling pathway  (ISO)
forebrain dorsal/ventral pattern formation  (ISO)
forebrain morphogenesis  (ISO)
forebrain neuron development  (ISO)
generation of neurons  (ISO)
gonad development  (ISO)
heart development  (ISO)
heart looping  (ISO)
heart morphogenesis  (ISO)
inner ear morphogenesis  (ISO)
kidney development  (ISO)
larynx morphogenesis  (ISO)
limb morphogenesis  (ISO)
lung development  (ISO)
lung morphogenesis  (ISO)
male genitalia development  (ISO)
MAPK cascade  (ISO)
mesodermal cell migration  (ISO)
mesonephros development  (ISO)
metanephros development  (ISO)
midbrain-hindbrain boundary development  (ISO)
motor neuron axon guidance  (ISO)
negative regulation of apoptotic process  (ISO)
negative regulation of cardiac muscle tissue development  (ISO)
negative regulation of neuron apoptotic process  (ISO)
neural plate morphogenesis  (ISO)
neuroepithelial cell differentiation  (ISO)
odontogenesis  (ISO)
organ induction  (ISO)
otic vesicle formation  (ISO)
outflow tract morphogenesis  (ISO)
outflow tract septum morphogenesis  (ISO)
pallium development  (ISO)
pharyngeal system development  (ISO)
positive regulation of cell population proliferation  (ISO)
positive regulation of ERK1 and ERK2 cascade  (ISO)
positive regulation of G protein-coupled receptor signaling pathway  (ISO)
positive regulation of gene expression  (ISO)
positive regulation of mitotic nuclear division  (ISO)
positive regulation of organ growth  (ISO)
positive regulation of peptidyl-tyrosine phosphorylation  (ISO)
regulation of odontogenesis of dentin-containing tooth  (ISO)
response to organic cyclic compound  (ISO)
response to oxidative stress  (ISO)
response to xenobiotic stimulus  (ISO)
signal transduction involved in regulation of gene expression  (ISO)
subpallium development  (ISO)
telencephalon development  (ISO)
thyroid gland development  (ISO)
thyroid-stimulating hormone-secreting cell differentiation  (ISO)

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References


Genomics

Comparative Map Data
Fgf8
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554858,517,412 - 8,521,770 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554858,517,412 - 8,521,732 (+)NCBIChiLan1.0ChiLan1.0
FGF8
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl10101,770,109 - 101,780,371 (-)EnsemblGRCh38hg38GRCh38
GRCh3810101,770,109 - 101,780,369 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh3710103,529,866 - 103,540,126 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 3610103,519,877 - 103,525,817 (-)NCBINCBI36hg18NCBI36
Build 3410103,519,876 - 103,525,817NCBI
Celera1097,268,628 - 97,274,500 (-)NCBI
Cytogenetic Map10q24.32NCBI
HuRef1097,160,317 - 97,170,664 (-)NCBIHuRef
CHM1_110103,813,541 - 103,823,715 (-)NCBICHM1_1
Fgf8
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391945,724,930 - 45,731,506 (-)NCBIGRCm39mm39
GRCm39 Ensembl1945,725,237 - 45,731,354 (-)Ensembl
GRCm381945,736,491 - 45,742,941 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1945,736,798 - 45,742,915 (-)EnsemblGRCm38mm10GRCm38
MGSCv371945,811,288 - 45,817,374 (-)NCBIGRCm37mm9NCBIm37
MGSCv361945,790,129 - 45,796,184 (-)NCBImm8
Celera1946,499,127 - 46,505,223 (-)NCBICelera
Cytogenetic Map19C3NCBI
cM Map1938.75NCBI
Fgf8
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21244,584,477 - 244,590,359 (-)NCBImRatBN7.2
Rnor_6.0 Ensembl1265,493,124 - 265,498,831 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.01265,492,949 - 265,498,965 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01272,923,589 - 272,929,296 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41250,951,023 - 250,956,730 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11251,211,591 - 251,217,299 (-)NCBI
Celera1240,393,901 - 240,399,608 (-)NCBICelera
Cytogenetic Map1q54NCBI
FGF8
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.110101,844,792 - 101,849,873 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl10101,844,792 - 101,853,916 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v01098,372,251 - 98,378,811 (-)NCBIMhudiblu_PPA_v0panPan3
FGF8
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12814,362,407 - 14,367,109 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2814,362,109 - 14,367,468 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2814,530,980 - 14,536,626 (-)NCBI
ROS_Cfam_1.02814,830,423 - 14,836,072 (-)NCBI
UMICH_Zoey_3.12814,376,915 - 14,382,561 (-)NCBI
UNSW_CanFamBas_1.02814,416,494 - 14,421,136 (-)NCBI
UU_Cfam_GSD_1.02814,548,787 - 14,554,435 (-)NCBI
Fgf8
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440721332,401,605 - 32,407,401 (+)NCBI
SpeTri2.0NW_0049366004,004,847 - 4,010,626 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
FGF8
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl14112,808,210 - 112,814,134 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.114112,808,215 - 112,814,225 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.214122,661,225 - 122,666,751 (-)NCBISscrofa10.2Sscrofa10.2susScr3
FGF8
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1994,797,157 - 94,803,725 (-)NCBI
ChlSab1.1 Ensembl994,798,088 - 94,803,629 (-)Ensembl
Vero_WHO_p1.0NW_02366604855,874,226 - 55,880,198 (-)NCBI
Fgf8
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046248311,251,991 - 1,259,247 (-)NCBI


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSCLAT00000001464   ⟹   ENSCLAP00000001422
RefSeq Status:
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_0049554858,517,412 - 8,521,770 (+)Ensembl
RefSeq Acc Id: XM_005403931   ⟹   XP_005403988
RefSeq Status:
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_0049554858,517,412 - 8,521,732 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_005403988 (Get FASTA)   NCBI Sequence Viewer  
Reference Sequences
RefSeq Acc Id: XP_005403988   ⟸   XM_005403931
- Sequence:
RefSeq Acc Id: ENSCLAP00000001422   ⟸   ENSCLAT00000001464


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCLAG00000001075 Ensembl, ENTREZGENE
Ensembl Protein ENSCLAP00000001422 ENTREZGENE
Ensembl Transcript ENSCLAT00000001464 ENTREZGENE
NCBI Gene Fgf8 ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-08-16 Fgf8  fibroblast growth factor 8    fibroblast growth factor 8 (androgen-induced)  Symbol and/or name change 5135510 APPROVED