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Gene: Abcc6 (ATP binding cassette subfamily C member 6) Chinchilla lanigera

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Symbol:

Abcc6

Name:

ATP binding cassette subfamily C member 6

RGD ID:

9001268

Description:

ENCODES a protein that exhibits ABC-type glutathione S-conjugate transporter activity (ortholog); ABC-type xenobiotic transporter activity (ortholog); ATP binding (ortholog); INVOLVED IN ATP metabolic process (ortholog); ATP transport (ortholog); calcium ion homeostasis (ortholog); PARTICIPATES IN multidrug resistance-associated protein mediated transport pathway; ASSOCIATED WITH Animal Disease Models (ortholog); arterial calcification of infancy (ortholog); autistic disorder (ortholog); FOUND IN apical plasma membrane (ortholog); basal plasma membrane (ortholog); basolateral plasma membrane (ortholog)

Type:

protein-coding

RefSeq Status:

MODEL

Previously known as:

ATP-binding cassette, sub-family C (CFTR/MRP), member 6; multidrug resistance-associated protein 6

RGD Orthologs

Alliance Orthologs

More Info

more info ...

Latest Assembly:

ChiLan1.0 - Chinchilla ChiLan1.0 Assembly

Position:

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955442	865,238 - 922,221 (-)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955442	865,292 - 921,739 (-)	NCBI	ChiLan1.0	ChiLan1.0

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

Animal Disease Models (ISO)

arterial calcification of infancy (ISO)

autistic disorder (ISO)

beta thalassemia (ISO)

Colorectal Neoplasms (ISO)

coronary artery disease (ISO)

cutis laxa (ISO)

Desbuquois Dysplasia 1 (ISO)

Disease Progression (ISO)

epilepsy (ISO)

Experimental Arthritis (ISO)

Eye Abnormalities (ISO)

Generalized Arterial Calcification of Infancy, 2 (ISO)

genetic disease (ISO)

globe disease (ISO)

intestinal volvulus (ISO)

nephrotic syndrome type 1 (ISO)

pseudoxanthoma elasticum (ISO)

Pseudoxanthoma Elasticum, Heterozygous (ISO)

schizophrenia (ISO)

Volvulus Of Midgut (ISO)

Wilson disease (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

ATP metabolic process (ISO)

ATP transport (ISO)

calcium ion homeostasis (ISO)

gene expression (ISO)

inhibition of non-skeletal tissue mineralization (ISO)

inorganic diphosphate transport (ISO)

intracellular phosphate ion homeostasis (ISO)

leukotriene transport (ISO)

phosphate ion homeostasis (ISO)

response to magnesium ion (ISO)

response to sodium phosphate (ISO)

xenobiotic transmembrane transport (ISO)

Cellular Component

apical plasma membrane (ISO)

basal plasma membrane (ISO)

basolateral plasma membrane (ISO)

extracellular region (ISO)

lateral plasma membrane (ISO)

nucleoplasm (ISO)

plasma membrane (ISO)

Molecular Function

ABC-type glutathione S-conjugate transporter activity (ISO)

ABC-type xenobiotic transporter activity (ISO)

ATP binding (ISO)

ATP hydrolysis activity (ISO)

ATPase-coupled transmembrane transporter activity (ISO)

inorganic diphosphate transmembrane transporter activity (ISO)

Molecular Pathway Annotations Click to see Annotation Detail View

multidrug resistance-associated protein mediated transport pathway (ISO)

References

References - curated

#	Reference Title	Reference Citation
1.	Transitive Annotation Pipeline	Automated assignment of GO, PW and RDO ISO annotations across species
2.	OMIM Disease Annotation Pipeline	OMIM Disease Annotation Pipeline

Additional References at PubMed

PMID:22301074	PMID:30032202

Genomics

Comparative Map Data

Abcc6
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955442	865,238 - 922,221 (-)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955442	865,292 - 921,739 (-)	NCBI	ChiLan1.0	ChiLan1.0

ABCC6
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	16	16,149,565 - 16,223,494 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	16	16,149,565 - 16,223,522 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	16	16,243,422 - 16,317,351 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	16	16,150,923 - 16,224,838 (-)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	16	16,151,490 - 16,224,815	NCBI
Celera	16	15,923,582 - 15,972,084 (-)	NCBI		Celera
Cytogenetic Map	16	p13.11	NCBI
HuRef	16	15,637,406 - 15,701,476 (-)	NCBI		HuRef
HuRef	16	17,226,645 - 17,228,924 (+)	NCBI		HuRef
CHM1_1	16	16,327,717 - 16,401,692 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	16	16,154,422 - 16,229,003 (-)	NCBI		T2T-CHM13v2.0

Abcc6
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	7	45,625,804 - 45,679,915 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	7	45,616,979 - 45,679,726 (-)	Ensembl		GRCm39 Ensembl
GRCm38	7	45,974,110 - 46,030,491 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	7	45,967,555 - 46,030,302 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	7	53,231,750 - 53,285,656 (-)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	7	45,844,422 - 45,898,327 (-)	NCBI		MGSCv36	mm8
MGSCv36	7	35,552,479 - 35,606,515 (-)	NCBI		MGSCv36	mm8
Celera	7	41,445,055 - 41,502,729 (-)	NCBI		Celera
Cytogenetic Map	7	B3	NCBI
cM Map	7	29.64	NCBI

Abcc6
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	1	105,583,681 - 105,637,895 (-)	NCBI		GRCr8
mRatBN7.2	1	96,447,224 - 96,501,464 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	1	96,447,251 - 96,501,464 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	1	101,833,395 - 101,887,602 (-)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	1	110,305,383 - 110,359,590 (-)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	1	103,595,749 - 103,649,961 (-)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	1	101,954,786 - 102,013,252 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	1	101,959,540 - 102,013,243 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	1	103,042,723 - 103,096,453 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	1	96,448,588 - 96,524,655 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	1	96,526,698 - 96,602,766 (-)	NCBI
Celera	1	90,699,816 - 90,752,348 (-)	NCBI		Celera
Cytogenetic Map	1	q22	NCBI

ABCC6
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	6	27,800,060 - 27,849,170 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	6	27,798,835 - 27,848,689 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	6	29,163,710 - 29,212,774 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	6	27,963,339 - 28,012,220 (+)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	6	27,963,425 - 28,011,739 (+)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	6	27,766,376 - 27,815,441 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	6	27,656,383 - 27,705,374 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	6	28,061,767 - 28,110,633 (+)	NCBI		UU_Cfam_GSD_1.0

Abcc6
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024409344	115,372,021 - 115,412,095 (-)	NCBI		HiC_Itri_2
SpeTri2.0	NW_004936501	3,469,928 - 3,508,577 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

ABCC6
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	3	28,261,214 - 28,356,706 (+)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	3	28,260,935 - 28,356,706 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	3	28,960,801 - 29,063,405 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

ABCC6
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	5	15,169,725 - 15,243,731 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	5	15,168,156 - 15,242,811 (-)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666068	14,739,120 - 14,812,929 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Abcc6
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624782	594,511 - 640,180 (-)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624782	590,174 - 640,576 (-)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Sequence

Nucleotide Sequences


RefSeq Transcripts	XM_005391081	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AGCD01037429	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AGCD01037430	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	GBCQ01155383	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSCLAT00000016027 ⟹ ENSCLAP00000015863

Type:

CODING

Position:

Chinchilla Assembly	Chr	Position (strand)	Source
ChiLan1.0 Ensembl	NW_004955442	865,238 - 922,221 (-)	Ensembl

Ensembl Acc Id:

ENSCLAT00000016028 ⟹ ENSCLAP00000015864

Type:

CODING

Position:

Chinchilla Assembly	Chr	Position (strand)	Source
ChiLan1.0 Ensembl	NW_004955442	865,238 - 922,221 (-)	Ensembl

Ensembl Acc Id:

ENSCLAT00000016029 ⟹ ENSCLAP00000015865

Type:

CODING

Position:

Chinchilla Assembly	Chr	Position (strand)	Source
ChiLan1.0 Ensembl	NW_004955442	866,010 - 921,398 (-)	Ensembl

RefSeq Acc Id:

XM_005391081 ⟹ XP_005391138

Type:

CODING

Position:

Chinchilla Assembly	Chr	Position (strand)	Source
ChiLan1.0	NW_004955442	865,292 - 921,739 (-)	NCBI

Sequence:

show sequence

ACAACCGCGTGCACGCCTGTCTGCTCTTCCACCAGGATAAACTCCAGGCATTGCTGGGTCCAAA
GGCCTTGGGGCGTTTGGGAAGGGACTTGTTGCTGGGAGCTGGGGAGAGTGTGGATTGTCGCTGC
ACCTTCGGGGGTTGGGGATCGCCTGGCCAGGTGCGGGCCTGGGCCTTCCGTCCACTTCCCTCGT
TCCGCCCGGGTCATCCCTACCCAGCCGCGCAGCCAGACCTTTGCCCCGCGCCTGGCGGTCGGAG
CTCCAGCCCCTCCTGGGCCCGCCCCCTGTCCAGAAGTGCTCGGCGGCAAGGCTGCAGGGACAGA
CGGACGCTGGACGCCGCTGGGACCGGCCGCGAGGCGCCAATGGCCGCGCCGAGCGAGCCCTGCG
CCGGGCCCGGGGTGTGGAACCAGACTGAGCCAGAACTTGCTGCCTCTCACCTGCTGAACCTGTG
CTTCCTGAGAGCAGTAGGGGTTTGGGTGCCTCCCCTGTACCTCTGGGTCCTTGGCCCCCTCTAC
CTCCTCTACATCTACCGCCATGGCCGAGGCTACCTCCGGATGTCCCCCCTCTTCAAAGCCAAAA
TGGTGCTTGGGTTTGCTCTCATCCTCCTGTGTACCTTCAATGTGGCCGTCCCTCTGTGGAGAAT
CCAGCAGGGGAAGCCCCAGGCCCCAGAAGCTCTTATTCATCCTACAGTGTGGCTCACCACCATG
AGCTTTGCCATGTTCCTGGTCCACATGGAGAGGAAGAAAGGCGTCCAGGCATCCGGGGTGCTAT
TTGGGTATTGGCTGCTCTGCTGTCTCCTGCCAGCTACCAGCGCTGTCCAGCAGGCCTCGAGTGG
GGACTTCCAGCGCGATCCCCTGAGCCACCTGTCCACTTACCTGTGTTTGTCTCTGGTCGTGGCT
GAGTTTGTGCTGTCCTGCATGGTGGATCAGCCCCCCTTCTTCCAGAAAGACCCCCAGCAGGCTA
ATCCATGCCCGGAAGCTGGGGCCTCCTTCCCCTCCAAGGCCACATTCTGGTGGGCTTCTAGGCT
TCTCTGGAAGGGCTACAGGAAGTCACTGAGACCAGAAGACCTTTGGTCCCTTGAGCCAGAAAAC
TCCTCAGAAGAACTTGTTTCCCAGCTGGAGAGGGAGTGGATAAGGAATCACAGTGTGGCCCAGG
GGTGCACCACGGTGTTGAAAGGCCGGGAGCAGGGAGGCCAGGCAGCCCGGGAGCTGGAGGCCCT
CCTGCCGCAAGGAGGGCGCCCAAGGGGCCCGCTGCTCAGGGCCATCTGGAGAGTGTTCCGCTGC
TCCTTCCTCCTGGGCACCCTCAGCCTCCTCATCGCTGACGCCTTCAGATTCGCAGTCCCCAAGC
TCCTCAGCCTGTTCCTGGAGTTCATGGGCAGCGCCCAGCGCCCCGCCTGGCAGGGCCCGCTGCT
CGCGGTGCTGCTGCTGCTCTCGGCCGGCCTGCAGACGCTGCTCGAGCAGCAGCACATGTTCCGG
CTCAAGGTGCTGCAGATGCGGCTGCGCGCGGCGCTCACCGGCCTGGTGTACAGAAAGGTCCTGC
TTCTGTCCCACGGAGCCAGGGAGTCCAGCGCCGTGGGGGACGTGGTCAACCTGCTCTCTGTGGA
CGTGCAGCGGCTCAGCGAGAGCGTCCTCTACCTCAACGGGCTCTGGCTGCCGCTGCTCTGGATC
AGCGTCTGCTTCGCCTACCTGTGGCAGCTCCTAGGGCCATCTGCCCTCACTGCCATCGCTGTTT
TCCTGGGCCTCCTTCCCCTGAATTTCTTTATCTCCAAGAAGAAGAACCACCATCAGGAAGAGCA
GATGAGGCAGAAGGACTCTCGGGCGCGGCTCACCAGCTTCGTCCTCAGGACCATGAGGACCATC
AAGTCGCACGGCTGGGAGGTAGCCTTCCTGGAGAGGGTCCTGCGCATCCGGGGCCGGGAGCTGG
GTGCCCTGAAGACCTCCACCCTCCTGTTCTCCGTGTCTCTGGTGTCCTTCCAAGTGTCCACGTT
TCTGGTTGCACTGGTCGTGTTTGCTGTCCACACTCTGGTGGCTGAAGAGAACACGATGGATGCA
GAGAAGGCCTTCGTGACCCTCACGGTGCTCGGCATCCTCAACAAGGCCCAGGCCTTCCTGCCCT
TCTGCATCCACTGTGTCATCCAGGCCCGGGTGTCCTTTGACCGCTTGGCCGCCTTCCTGTACCT
GGAAGAAGTTGACCCTGGCGCTGTGGCCTCGAGTCCCTCCAGATGCTCCCCTGGGAAGGACTGC
ATCACCATACAGGATGGCACCTTCGCATGGTCCCGGGAGAGCCCTCCCTGCCTGCACAGGATCA
ACCTCACTGTGCCCCAGGGCTGTCTGCTGGCTGTTGTGGGTCCAGTGGGGGCAGGGAAATCCTC
CCTGCTCTCCGCCCTCCTCGGAGAGCTGTCAAAGCTCGAAGGGTCTGTGAGCGTCCAGGGAACA
GTGGCTTACGTGCCCCAAGAGGCCTGGGTACAGAACACCTCAGTGGTGGAGAACGTGTGCTTCC
GGCAGGAGCTGGACATGCCCTGGCTGGAGAGAGTGTTGGAGGGCTGTGCCCTGGGGCCAGATGT
GGATAGCTTTCCTGCCGGCATGCACACCCCAATTGGAGAGCAGGGCATGAACCTCTCTGGGGGC
CAGAAGCAGCGGCTGAGCCTTGCCCGGGCTGTGTACAGAAAGGCTACTGTGTACCTGCTGGACG
ATCCCCTGGCCGCCCTGGATGCCCATGTTGGCCAGCATGTCTTCAACCAGGTCATTGGGCCCAG
TGGGCTGCTCCAAGGAACGACCCGGATCCTTGTGACCCACACGCTCCACGTCCTACCCCAGGCC
GATCAGATTGTGGTGCTGGCAGACGGTGCCATTGCAGAGATGGGCTCCTACCAGGAGCTGCTGC
ACAGGAAGGGGGCCCTGGTGGCACTTCTGGAGGGGGCCGGACAGCCAGGAGGTGGAGAAGATGG
AGAAACAGAAACTGCAGCCAACACCAGTGGCCCTGGAGGTGGAAGGCCTGAACACAGACCAGAG
AGGTCCGTAAAGTCAGCCCCTATGATGGACAATGTCATCTCAGAAGCCCAGACAGAAGCTCCTC
TAGATGATCCTGAGAGGGCAGGACGGCCAATACGAGAGGGCAGTGTGCGGTATGGCCGGGTGAA
GGCTGCCATGTACCTGAGCTACCTGCGAGCCACAGGCATCCCCCTCTGCGCCTACACGCTCTTC
CTCTTCCTCTGCCAGCAAGTGGCCTCCTTCTGCCGGGGATACTGGCTGAGTCTGTGGGCGGATG
ACCCAGTTGTGGATGGGCAGCAGATGCAGACAGCCTTACGCGGCTGGGTCTTTGGGCTCCTCGG
CTGTCTCCAAGCCATTGGGCTGTTTGCCTCCATGGCCGCAGTGTTCGTGGGTGGGATCCAGGCA
TCCAGCCTGCTCTTCCAGAGGCTCCTGTGGGATGTGGCTCGGTCTCCCATTGGCTTCTTTGAGC
GAACACCTGTTGGGAAGCTGCTGAACTACTTCTCCAAGGAAATGGACACGGTGGATGTGGAAAT
CCCAGACAAGCTCCAGGCCTTGCTGACTTACACATTCGGACTGCTAGAGGTCTGCCTGGCAGTG
ACGATGGTCACGCCCCTGGCCGTCGTGGCCATCCTGCCGCTGATGCTCCTTTATGCTGGGTTTC
AGAGCCTGTACGTGGCCATCTCATGCCAGCTGAGACGCATGGAGTCAGCCAGCTACTCATCTGT
GTGCTCCCACGTGGCCGAGACATTCCAGGGCAGCGCAGTGGTCAGGGCGTTCCAAGCCCAGCAC
CACTTTGTGGCTCGGAGCGATTCCCTCATGGATGTGAACCAGAGGGTCAGTTTCCCACGACTGG
TGGCTGACAGATGGCTCGCTACCAACCTGGAGCTCCTGGGGAACAGCCTGGTGTTCGTGGCTGC
CATGTGCGCTGTGCTGAGCAAGGCCCACCTCAGTGCTGGCCTCGTGGGGTTTTCTGTCTCAGCC
GCCCTCCAGGTGACCCAGACCCTGCAGTGGGTTGTTCGCAGCTGGACAGACCTGGAAAACAGCA
TGGTGTCAGTGGAGCGGGTGCAGGACTACGCCCGCACGCCCAAGGAGGCTCCCTGGACGCTGCC
TACCTGTGCAGCCCGGCCCCCCTGGCCTCACGGGGGACAGATAGAGTTCCAGAACTTTGGGCTG
AGACACCGGCCGGAGCTCCCATTTGCTGTGCGGGGCGTGTCCTTCCAGATCCACGCAGGAGAGA
AGGTCGGCATCGTGGGCAGGACAGGGGCTGGGAAGTCCTCCCTGGCAGGGGGCCTGCTGCGGCT
GCAGGAGGCAGCAGAGGGTGGCATCTGGATCGACGGGGTCCCCATCGACCAAGTGGGGCTGCAC
ACACTGCGGTCCAGGATCACCATCATCCCGCAGGACCCCATCCTGGTCCCTGGCTCTCTGCGGA
TGAACCTGGACCTGCGGCAAGAGCACAGCGATGACGCTCTCTGGGCGGCCTTGGAGACTGTGCA
GCTCAAAGACTTTGTGGCCAGCCTGCCCGGCCAGCTGCAGTACGAGTGTGCAGAGCACGGTGAC
AATCTGAGCGTGGGTCAGAAGCAGCTCCTGTGTCTGGCACGTGCCCTGCTCCGGAAAACCCAGA
TTCTCATCCTAGATGAAGCCACGGCCTCAGTGGACCTGGGGACAGAGCTCCAGATGCAGGCGGC
CCTCGGGCACTGGTTTGCTCAGTGCACGGTGCTGCTCATCGCCCACCGCCTGCACTCGGTGATG
GACTGTGCCAGGGTACTGGTCATGGACAATGGGCAGGTGGCAGAGAGTGGAAGCCCAGCCCAGC
TGTTGGCCCAGAAGGGACTGTTTTACAGGCTGGCCCAGGAGTCAGGCCTCGTCTGAGCCTAGCC
TCCCCACTGTCCCTGGCGGGGTCAGCCCCAGAACCTGCTGTGCCACGGAGAAGCCAGTGACCCA
GGCTGTGTGTGGTCCCAGGTAGTGTTGTGGTCTCCAAGAGGAAAATGGCAAAGAAAGTGTCTGA
GTATCACCAGTAGGAGACCCCGAAGGACACAGCCAACCCAGGCTGACCGGGGCAGGGCCCATCC
TGCCCTGTCTACCCTGGAGCCAACGTCAGCAGTGACTTTCAGTCCTCGTTGCTTATAAGTCTCA
CATGGAGGGCAGAAAAGCATGTCTGCCCTCGGTTCTATGCCCCAGATGAATTAAATCAGAATTC
ATGGGGCTGGGGCAATGGTGTGTGTAGTTAATCCAAATTAATCTTATTTTGAGATAATCATAGA
TTCACATGCAATTTTAAGAAACTGGTGTGGTGGTACGTGCATGTAATCCTAGTTACCTGGGGGG
CTGAGACAGAAGGACTAGCTTGGGCAACTTAGTGAGACTTTATCTCAAATTTAAAAGGGGCTGG
GGGTGTAGCTCAGTAGAATAGTACTTGCCTAGCATGCATGTGCCCCTGGGTTCCATCTCCAGTA
CCACAAAATGAAACCAGGGATCTCCTGGGCCCTTTACCATTTCTCCCAGTGTTGACATCTTGTA
CAACTCTCAGGCAAGATCACAGCAGGATATAGACATCAATAAAACTACCAATCTGGTTCAGCTT
TTCTGA

hide sequence

Protein Sequences


Protein RefSeqs	XP_005391138	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSCLAP00000015863.1
	ENSCLAP00000015864
	ENSCLAP00000015864.1
	ENSCLAP00000015865.1

RefSeq Acc Id:

XP_005391138 ⟸ XM_005391081

- UniProtKB:

A0A8C2VHS6 (UniProtKB/TrEMBL), A0A8C2YQI2 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MAAPSEPCAGPGVWNQTEPELAASHLLNLCFLRAVGVWVPPLYLWVLGPLYLLYIYRHGRGYLR
MSPLFKAKMVLGFALILLCTFNVAVPLWRIQQGKPQAPEALIHPTVWLTTMSFAMFLVHMERKK
GVQASGVLFGYWLLCCLLPATSAVQQASSGDFQRDPLSHLSTYLCLSLVVAEFVLSCMVDQPPF
FQKDPQQANPCPEAGASFPSKATFWWASRLLWKGYRKSLRPEDLWSLEPENSSEELVSQLEREW
IRNHSVAQGCTTVLKGREQGGQAARELEALLPQGGRPRGPLLRAIWRVFRCSFLLGTLSLLIAD
AFRFAVPKLLSLFLEFMGSAQRPAWQGPLLAVLLLLSAGLQTLLEQQHMFRLKVLQMRLRAALT
GLVYRKVLLLSHGARESSAVGDVVNLLSVDVQRLSESVLYLNGLWLPLLWISVCFAYLWQLLGP
SALTAIAVFLGLLPLNFFISKKKNHHQEEQMRQKDSRARLTSFVLRTMRTIKSHGWEVAFLERV
LRIRGRELGALKTSTLLFSVSLVSFQVSTFLVALVVFAVHTLVAEENTMDAEKAFVTLTVLGIL
NKAQAFLPFCIHCVIQARVSFDRLAAFLYLEEVDPGAVASSPSRCSPGKDCITIQDGTFAWSRE
SPPCLHRINLTVPQGCLLAVVGPVGAGKSSLLSALLGELSKLEGSVSVQGTVAYVPQEAWVQNT
SVVENVCFRQELDMPWLERVLEGCALGPDVDSFPAGMHTPIGEQGMNLSGGQKQRLSLARAVYR
KATVYLLDDPLAALDAHVGQHVFNQVIGPSGLLQGTTRILVTHTLHVLPQADQIVVLADGAIAE
MGSYQELLHRKGALVALLEGAGQPGGGEDGETETAANTSGPGGGRPEHRPERSVKSAPMMDNVI
SEAQTEAPLDDPERAGRPIREGSVRYGRVKAAMYLSYLRATGIPLCAYTLFLFLCQQVASFCRG
YWLSLWADDPVVDGQQMQTALRGWVFGLLGCLQAIGLFASMAAVFVGGIQASSLLFQRLLWDVA
RSPIGFFERTPVGKLLNYFSKEMDTVDVEIPDKLQALLTYTFGLLEVCLAVTMVTPLAVVAILP
LMLLYAGFQSLYVAISCQLRRMESASYSSVCSHVAETFQGSAVVRAFQAQHHFVARSDSLMDVN
QRVSFPRLVADRWLATNLELLGNSLVFVAAMCAVLSKAHLSAGLVGFSVSAALQVTQTLQWVVR
SWTDLENSMVSVERVQDYARTPKEAPWTLPTCAARPPWPHGGQIEFQNFGLRHRPELPFAVRGV
SFQIHAGEKVGIVGRTGAGKSSLAGGLLRLQEAAEGGIWIDGVPIDQVGLHTLRSRITIIPQDP
ILVPGSLRMNLDLRQEHSDDALWAALETVQLKDFVASLPGQLQYECAEHGDNLSVGQKQLLCLA
RALLRKTQILILDEATASVDLGTELQMQAALGHWFAQCTVLLIAHRLHSVMDCARVLVMDNGQV
AESGSPAQLLAQKGLFYRLAQESGLV

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Ensembl Acc Id:

ENSCLAP00000015865 ⟸ ENSCLAT00000016029

Ensembl Acc Id:

ENSCLAP00000015864 ⟸ ENSCLAT00000016028

Ensembl Acc Id:

ENSCLAP00000015863 ⟸ ENSCLAT00000016027

Protein Domains

ABC transmembrane type-1 ABC transporter

Additional Information

External Database Links

Database	Acc Id	Source(s)
Ensembl Genes	ENSCLAG00000010909	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSCLAT00000016027.1	UniProtKB/TrEMBL
	ENSCLAT00000016028	ENTREZGENE
	ENSCLAT00000016028.1	UniProtKB/TrEMBL
	ENSCLAT00000016029.1	UniProtKB/TrEMBL
Gene3D-CATH	1.20.1560.10	UniProtKB/TrEMBL
	3.40.50.300	UniProtKB/TrEMBL
InterPro	AAA+_ATPase	UniProtKB/TrEMBL
	ABC1_TM_dom	UniProtKB/TrEMBL
	ABC1_TM_sf	UniProtKB/TrEMBL
	ABC_transporter-like_ATP-bd	UniProtKB/TrEMBL
	ABC_transporter-like_CS	UniProtKB/TrEMBL
	ABC_transporter_C	UniProtKB/TrEMBL
	Multidrug-R_assoc	UniProtKB/TrEMBL
	P-loop_NTPase	UniProtKB/TrEMBL
NCBI Gene	Abcc6	ENTREZGENE
PANTHER	ATP-BINDING CASSETTE SUB-FAMILY C	UniProtKB/TrEMBL
	PTHR24223:SF339	UniProtKB/TrEMBL
Pfam	ABC_membrane	UniProtKB/TrEMBL
	ABC_tran	UniProtKB/TrEMBL
PROSITE	ABC_TM1F	UniProtKB/TrEMBL
	ABC_TRANSPORTER_1	UniProtKB/TrEMBL
	ABC_TRANSPORTER_2	UniProtKB/TrEMBL
SMART	AAA	UniProtKB/TrEMBL
Superfamily-SCOP	SSF52540	UniProtKB/TrEMBL
	SSF90123	UniProtKB/TrEMBL
UniProt	A0A8C2VHS6	ENTREZGENE, UniProtKB/TrEMBL
	A0A8C2VHY0_CHILA	UniProtKB/TrEMBL
	A0A8C2YQI2	ENTREZGENE, UniProtKB/TrEMBL

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2016-08-16	Abcc6	ATP binding cassette subfamily C member 6		ATP-binding cassette, sub-family C (CFTR/MRP), member 6	Symbol and/or name change	5135510	APPROVED

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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Imported Disease Annotations - CTD

Imported Disease Annotations - OMIM

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