Hacd3 (3-hydroxyacyl-CoA dehydratase 3) - Rat Genome Database

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Gene: Hacd3 (3-hydroxyacyl-CoA dehydratase 3) Chinchilla lanigera
Analyze
Symbol: Hacd3
Name: 3-hydroxyacyl-CoA dehydratase 3
RGD ID: 9000739
Description: ENCODES a protein that exhibits enzyme binding (ortholog); very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase activity (ortholog); INVOLVED IN fatty acid elongation (ortholog); JNK cascade (ortholog); negative regulation of intracellular signal transduction (ortholog); ASSOCIATED WITH Bloom syndrome (ortholog); colorectal cancer (ortholog); genetic disease (ortholog); FOUND IN endoplasmic reticulum (ortholog); nuclear membrane (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: Ptplad1; very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase 3
RGD Orthologs
Human
Mouse
Rat
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: ChiLan1.0 - Chinchilla ChiLan1.0 Assembly
Position:
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554509,923,560 - 9,942,658 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554509,923,560 - 9,947,519 (-)NCBIChiLan1.0ChiLan1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Transitive Annotation Pipeline Automated assignment of GO, PW and RDO ISO annotations across species
Additional References at PubMed
PMID:30032202  


Genomics

Comparative Map Data
Hacd3
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554509,923,560 - 9,942,658 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554509,923,560 - 9,947,519 (-)NCBIChiLan1.0ChiLan1.0
HACD3
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381565,530,463 - 65,578,349 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1565,530,418 - 65,578,349 (+)EnsemblGRCh38hg38GRCh38
GRCh371565,822,801 - 65,870,687 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361563,596,687 - 63,657,746 (+)NCBINCBI36Build 36hg18NCBI36
Cytogenetic Map15q22.31NCBI
HuRef1542,647,165 - 42,694,915 (+)NCBIHuRef
CHM1_11565,939,303 - 65,988,576 (+)NCBICHM1_1
T2T-CHM13v2.01563,339,879 - 63,387,748 (+)NCBIT2T-CHM13v2.0
Hacd3
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39964,894,265 - 64,929,014 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl964,894,265 - 64,928,975 (-)EnsemblGRCm39 Ensembl
GRCm38964,986,983 - 65,021,732 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl964,986,983 - 65,021,693 (-)EnsemblGRCm38mm10GRCm38
MGSCv37964,834,790 - 64,869,524 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36964,784,989 - 64,819,707 (-)NCBIMGSCv36mm8
Celera962,217,503 - 62,252,121 (-)NCBICelera
Cytogenetic Map9CNCBI
cM Map935.03NCBI
Hacd3
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8874,396,441 - 74,433,700 (-)NCBIGRCr8
mRatBN7.2865,501,240 - 65,538,507 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl865,501,240 - 65,538,507 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx871,013,916 - 71,051,073 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0869,286,919 - 69,324,085 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0867,156,406 - 67,193,771 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0870,471,572 - 70,509,874 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl870,471,572 - 70,509,874 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0870,170,452 - 70,207,419 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4869,243,485 - 69,264,608 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera864,903,974 - 64,941,302 (-)NCBICelera
Cytogenetic Map8q24NCBI
HACD3
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21654,780,341 - 54,827,712 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11558,951,436 - 58,998,788 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01544,473,542 - 44,520,885 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11562,752,762 - 62,799,950 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1562,752,762 - 62,799,950 (+)Ensemblpanpan1.1panPan2
HACD3
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13029,880,567 - 29,920,932 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl3029,880,419 - 29,920,332 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha3029,808,822 - 29,849,130 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.03030,071,073 - 30,111,424 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl3030,071,073 - 30,111,422 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.13030,000,774 - 30,041,004 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.03030,062,778 - 30,103,002 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.03030,303,383 - 30,343,767 (+)NCBIUU_Cfam_GSD_1.0
Hacd3
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024408640107,948,625 - 107,981,873 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493647125,796,620 - 25,829,948 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493647125,796,666 - 25,829,278 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
HACD3
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1163,525,965 - 163,588,798 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11163,525,872 - 163,567,649 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21181,100,316 - 181,141,934 (+)NCBISscrofa10.2Sscrofa10.2susScr3
HACD3
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12618,002,618 - 18,050,302 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2618,004,586 - 18,050,258 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666048123,390,731 - 123,439,052 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Hacd3
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247817,007,155 - 7,043,244 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247817,007,155 - 7,043,165 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSCLAT00000015762   ⟹   ENSCLAP00000015600
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_0049554509,923,560 - 9,942,658 (-)Ensembl
RefSeq Acc Id: XM_005393882   ⟹   XP_005393939
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_0049554509,923,560 - 9,947,519 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_005393939 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSCLAP00000015600
  ENSCLAP00000015600.1
Reference Protein Sequences
RefSeq Acc Id: XP_005393939   ⟸   XM_005393882
- UniProtKB: A0A8C2VH68 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSCLAP00000015600   ⟸   ENSCLAT00000015762
Protein Domains
CS


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCLAG00000010725 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCLAT00000015762 ENTREZGENE
  ENSCLAT00000015762.1 UniProtKB/TrEMBL
Gene3D-CATH 2.60.40.790 UniProtKB/TrEMBL
InterPro CS_dom UniProtKB/TrEMBL
  HSP20-like_chaperone UniProtKB/TrEMBL
  Tyr_Pase-like_PTPLA UniProtKB/TrEMBL
NCBI Gene Ptplad1 ENTREZGENE
PANTHER PTHR11035 UniProtKB/TrEMBL
  VERY-LONG-CHAIN (3R)-3-HYDROXYACYL-COA DEHYDRATASE 3 UniProtKB/TrEMBL
Pfam PTPLA UniProtKB/TrEMBL
PROSITE PS51203 UniProtKB/TrEMBL
Superfamily-SCOP SSF49764 UniProtKB/TrEMBL
UniProt A0A8C2VH68 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2015-08-25 Hacd3  3-hydroxyacyl-CoA dehydratase 3  Ptplad1  protein tyrosine phosphatase-like A domain containing 1  Symbol and/or name change 5135510 APPROVED