Sgk2 (serum/glucocorticoid regulated kinase 2) - Rat Genome Database

Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Gene: Sgk2 (serum/glucocorticoid regulated kinase 2) Chinchilla lanigera
Analyze
Symbol: Sgk2
Name: serum/glucocorticoid regulated kinase 2
RGD ID: 8996849
Description: ENCODES a protein that exhibits potassium channel regulator activity (ortholog); ASSOCIATED WITH colorectal cancer (ortholog); Experimental Liver Cirrhosis (ortholog); focal epilepsy (ortholog); FOUND IN nucleoplasm (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: serine/threonine-protein kinase Sgk2; SGK2, serine/threonine kinase 2
RGD Orthologs
Human
Mouse
Rat
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: ChiLan1.0 - Chinchilla ChiLan1.0 Assembly
Position:
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495544513,581,145 - 13,625,320 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495544513,581,145 - 13,625,320 (-)NCBIChiLan1.0ChiLan1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
nucleoplasm  (ISO)

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Transitive Annotation Pipeline Automated assignment of GO, PW and RDO ISO annotations across species
Additional References at PubMed
PMID:22301074  


Genomics

Comparative Map Data
Sgk2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495544513,581,145 - 13,625,320 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495544513,581,145 - 13,625,320 (-)NCBIChiLan1.0ChiLan1.0
SGK2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382043,559,027 - 43,585,627 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2043,558,968 - 43,588,237 (+)EnsemblGRCh38hg38GRCh38
GRCh372042,187,667 - 42,214,267 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 362041,621,100 - 41,647,687 (+)NCBINCBI36Build 36hg18NCBI36
Build 342041,621,099 - 41,647,686NCBI
Celera2038,895,152 - 38,921,737 (+)NCBICelera
Cytogenetic Map20q13.12NCBI
HuRef2038,923,264 - 38,950,126 (+)NCBIHuRef
CHM1_12042,091,437 - 42,118,025 (+)NCBICHM1_1
T2T-CHM13v2.02045,292,229 - 45,318,829 (+)NCBIT2T-CHM13v2.0
Sgk2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm392162,829,249 - 162,856,059 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl2162,829,250 - 162,856,047 (+)EnsemblGRCm39 Ensembl
GRCm382162,987,327 - 163,014,139 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl2162,987,330 - 163,014,127 (+)EnsemblGRCm38mm10GRCm38
MGSCv372162,813,217 - 162,839,863 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv362162,678,987 - 162,705,568 (+)NCBIMGSCv36mm8
Celera2168,934,488 - 168,961,119 (+)NCBICelera
Cytogenetic Map2H2NCBI
cM Map283.93NCBI
Sgk2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr83172,063,625 - 172,089,000 (+)NCBIGRCr8
mRatBN7.23151,644,102 - 151,669,480 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl3151,644,102 - 151,669,480 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx3155,452,311 - 155,477,655 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.03163,951,255 - 163,976,603 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.03161,694,860 - 161,720,202 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.03159,361,313 - 159,385,843 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl3159,368,273 - 159,384,775 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.03165,557,662 - 165,581,916 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.43153,849,825 - 153,890,111 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.13153,778,278 - 153,794,932 (+)NCBI
Celera3150,301,782 - 150,326,821 (+)NCBICelera
Cytogenetic Map3q42NCBI
SGK2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22149,304,906 - 49,331,003 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12049,298,365 - 49,324,092 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02039,897,338 - 39,924,767 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12040,992,171 - 41,018,587 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2040,997,536 - 41,018,587 (+)Ensemblpanpan1.1panPan2
SGK2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12431,272,395 - 31,294,409 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2431,272,493 - 31,294,195 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2430,916,070 - 30,938,174 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02431,986,104 - 32,001,288 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2431,980,261 - 32,001,114 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12431,243,810 - 31,265,914 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02431,355,174 - 31,377,248 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02431,895,633 - 31,917,764 (+)NCBIUU_Cfam_GSD_1.0
Sgk2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024408640180,280,673 - 180,302,503 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365303,008,161 - 3,024,218 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365303,007,934 - 3,025,552 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
SGK2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1746,188,265 - 46,208,804 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11746,188,160 - 46,208,807 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21751,626,067 - 51,649,666 (+)NCBISscrofa10.2Sscrofa10.2susScr3
SGK2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1220,217,768 - 20,245,675 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl220,218,420 - 20,246,186 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605068,961,022 - 68,988,744 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Sgk2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462479010,726,486 - 10,752,235 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462479010,727,125 - 10,749,060 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence


RefSeq Acc Id: ENSCLAT00000015743   ⟹   ENSCLAP00000015581
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_00495544513,581,145 - 13,625,320 (-)Ensembl
RefSeq Acc Id: ENSCLAT00000015744   ⟹   ENSCLAP00000015582
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_00495544513,584,042 - 13,599,348 (-)Ensembl
RefSeq Acc Id: XM_005392499   ⟹   XP_005392556
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_00495544513,581,145 - 13,625,320 (-)NCBI
Sequence:
RefSeq Acc Id: XM_013518253   ⟹   XP_013373707
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_00495544513,581,145 - 13,625,320 (-)NCBI
Sequence:
RefSeq Acc Id: XR_001235575
Type: NON-CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_00495544513,581,145 - 13,625,320 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_005392556 (Get FASTA)   NCBI Sequence Viewer  
  XP_013373707 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSCLAP00000015581.1
  ENSCLAP00000015582.1
RefSeq Acc Id: XP_005392556   ⟸   XM_005392499
- Sequence:
RefSeq Acc Id: XP_013373707   ⟸   XM_013518253
- Sequence:
RefSeq Acc Id: ENSCLAP00000015582   ⟸   ENSCLAT00000015744
RefSeq Acc Id: ENSCLAP00000015581   ⟸   ENSCLAT00000015743

Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCLAG00000010710 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCLAT00000015743 ENTREZGENE
  ENSCLAT00000015743.1 UniProtKB/TrEMBL
  ENSCLAT00000015744.1 UniProtKB/TrEMBL
Gene3D-CATH Transferase(Phosphotransferase) domain 1 UniProtKB/TrEMBL
InterPro AGC-kinase_C UniProtKB/TrEMBL
  Kinase-like_dom_sf UniProtKB/TrEMBL
  Pkinase_C UniProtKB/TrEMBL
  Prot_kinase_dom UniProtKB/TrEMBL
  Protein_kinase_ATP_BS UniProtKB/TrEMBL
  Ser/Thr_kinase_AS UniProtKB/TrEMBL
NCBI Gene Sgk2 ENTREZGENE
PANTHER RIBOSOMAL PROTEIN S6 KINASE UniProtKB/TrEMBL
  SERUM/GLUCOCORTICOID REGULATED KINASE 2 UniProtKB/TrEMBL
Pfam Pkinase UniProtKB/TrEMBL
  Pkinase_C UniProtKB/TrEMBL
PROSITE AGC_KINASE_CTER UniProtKB/TrEMBL
  PROTEIN_KINASE_ATP UniProtKB/TrEMBL
  PROTEIN_KINASE_DOM UniProtKB/TrEMBL
  PROTEIN_KINASE_ST UniProtKB/TrEMBL
SMART S_TK_X UniProtKB/TrEMBL
  S_TKc UniProtKB/TrEMBL
Superfamily-SCOP SSF56112 UniProtKB/TrEMBL
UniProt A0A8C2VJ96_CHILA UniProtKB/TrEMBL
  A0A8C2VL67_CHILA UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2019-02-05 Sgk2  serum/glucocorticoid regulated kinase 2    SGK2, serine/threonine kinase 2  Symbol and/or name change 5135510 APPROVED
2016-08-03 Sgk2  SGK2, serine/threonine kinase 2    serum/glucocorticoid regulated kinase 2  Symbol and/or name change 5135510 APPROVED