Fgfr2 (fibroblast growth factor receptor 2) - Rat Genome Database

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Gene: Fgfr2 (fibroblast growth factor receptor 2) Chinchilla lanigera
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Symbol: Fgfr2
Name: fibroblast growth factor receptor 2
RGD ID: 8995041
Description: ENCODES a protein that exhibits fibroblast growth factor binding (ortholog); fibroblast growth factor-activated receptor activity (ortholog); identical protein binding (ortholog); INVOLVED IN angiogenesis (ortholog); animal organ morphogenesis (ortholog); axonogenesis (ortholog); PARTICIPATES IN fibroblast growth factor signaling pathway; ASSOCIATED WITH Acneiform Eruptions (ortholog); acrocephalosyndactylia (ortholog); adenoid cystic carcinoma (ortholog); FOUND IN cell cortex (ortholog); cell surface (ortholog); collagen-containing extracellular matrix (ortholog)
Type: protein-coding
RefSeq Status: MODEL
RGD Orthologs
Human
Mouse
Rat
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: ChiLan1.0 - Chinchilla ChiLan1.0 Assembly
NCBI Annotation Information: Annotation category: partial on reference assembly
Position:
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_0049555512,321,190 - 2,427,000 (-)NCBIChiLan1.0ChiLan1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View
Acneiform Eruptions  (ISO)
acrocephalosyndactylia  (ISO)
adenoid cystic carcinoma  (ISO)
ankylosis  (ISO)
Anorectal Malformations  (ISO)
Antley-Bixler syndrome  (ISO)
ANTLEY-BIXLER SYNDROME WITHOUT GENITAL ANOMALIES OR DISORDERED STEROIDOGENESIS  (ISO)
Beare-Stevenson cutis gyrata syndrome  (ISO)
Bent Bone Dysplasia Syndrome  (ISO)
breast cancer  (ISO)
Breast Neoplasms  (ISO)
Burns, Chemical  (ISO)
cholangiocarcinoma  (ISO)
cleft lip  (ISO)
cleft palate  (ISO)
colorectal cancer  (ISO)
Congenital Limb Deformities  (ISO)
Craniofacial Abnormalities  (ISO)
craniosynostosis  (ISO)
Craniosynostosis Syndrome, Autosomal Recessive  (ISO)
Crouzon syndrome  (ISO)
developmental coordination disorder  (ISO)
duodenal atresia  (ISO)
dysgerminoma  (ISO)
endometrial cancer  (ISO)
endometrial carcinoma  (ISO)
Endometrial Neoplasms  (ISO)
Endometrioid Carcinomas  (ISO)
endometriosis  (ISO)
Epstein-Barr Virus Infections  (ISO)
esophageal carcinoma  (ISO)
gastric adenocarcinoma  (ISO)
genetic disease  (ISO)
Head and Neck Neoplasms  (ISO)
hepatocellular carcinoma  (ISO)
Hypertelorism  (ISO)
hypospadias  (ISO)
intellectual disability  (ISO)
Jackson-Weiss syndrome  (ISO)
LADD syndrome  (ISO)
liver cirrhosis  (ISO)
lung adenocarcinoma  (ISO)
Lung Neoplasms  (ISO)
lung squamous cell carcinoma  (ISO)
Lymphatic Metastasis  (ISO)
Multiple Abnormalities  (ISO)
Nasopharyngeal Neoplasms  (ISO)
Ovarian Neoplasms  (ISO)
Pfeiffer syndrome  (ISO)
Plagiocephaly, Nonsynostotic  (ISO)
prostate cancer  (ISO)
prostate carcinoma in situ  (ISO)
PTEN hamartoma tumor syndrome  (ISO)
retinitis pigmentosa  (ISO)
Saethre-Chotzen syndrome  (ISO)
Scaphocephaly, Maxillary Retrusion, and Mental Retardation  (ISO)
Skin Abnormalities  (ISO)
skin disease  (ISO)
spina bifida  (ISO)
split hand-foot malformation  (ISO)
squamous cell carcinoma  (ISO)
stomach cancer  (ISO)
Stomach Neoplasms  (ISO)
Tooth Abnormalities  (ISO)
Tracheoesophageal Fistula  (ISO)
transitional cell carcinoma  (ISO)
umbilical hernia  (ISO)
urinary bladder cancer  (ISO)
uterine cancer  (ISO)
uterine carcinosarcoma  (ISO)
Uterine Cervical Neoplasms  (ISO)
Volvulus Of Midgut  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process
angiogenesis  (ISO)
animal organ morphogenesis  (ISO)
axonogenesis  (ISO)
bone development  (ISO)
bone mineralization  (ISO)
bone morphogenesis  (ISO)
branch elongation involved in salivary gland morphogenesis  (ISO)
branching involved in labyrinthine layer morphogenesis  (ISO)
branching involved in prostate gland morphogenesis  (ISO)
branching involved in salivary gland morphogenesis  (ISO)
branching morphogenesis of a nerve  (ISO)
bud elongation involved in lung branching  (ISO)
cell fate commitment  (ISO)
cell-cell signaling  (ISO)
cellular response to fibroblast growth factor stimulus  (ISO)
cellular response to retinoic acid  (ISO)
cellular response to transforming growth factor beta stimulus  (ISO)
coronal suture morphogenesis  (ISO)
digestive tract development  (ISO)
embryonic cranial skeleton morphogenesis  (ISO)
embryonic digestive tract morphogenesis  (ISO)
embryonic organ development  (ISO)
embryonic organ morphogenesis  (ISO)
embryonic pattern specification  (ISO)
endochondral bone growth  (ISO)
endodermal digestive tract morphogenesis  (ISO)
epidermis morphogenesis  (ISO)
epithelial cell differentiation  (ISO)
epithelial cell proliferation involved in salivary gland morphogenesis  (ISO)
epithelial to mesenchymal transition  (ISO)
epithelial tube branching involved in lung morphogenesis  (ISO)
fibroblast growth factor receptor signaling pathway  (ISO)
fibroblast growth factor receptor signaling pathway involved in hemopoiesis  (ISO)
fibroblast growth factor receptor signaling pathway involved in mammary gland specification  (ISO)
fibroblast growth factor receptor signaling pathway involved in negative regulation of apoptotic process in bone marrow cell  (ISO)
fibroblast growth factor receptor signaling pathway involved in orbitofrontal cortex development  (ISO)
fibroblast growth factor receptor signaling pathway involved in positive regulation of cell proliferation in bone marrow  (ISO)
gland morphogenesis  (ISO)
hair follicle morphogenesis  (ISO)
in utero embryonic development  (ISO)
inner ear morphogenesis  (ISO)
lacrimal gland development  (ISO)
lateral sprouting from an epithelium  (ISO)
lens fiber cell development  (ISO)
limb bud formation  (ISO)
lung alveolus development  (ISO)
lung development  (ISO)
lung lobe morphogenesis  (ISO)
lung-associated mesenchyme development  (ISO)
mammary gland bud formation  (ISO)
membranous septum morphogenesis  (ISO)
mesenchymal cell differentiation  (ISO)
mesenchymal cell differentiation involved in lung development  (ISO)
mesenchymal cell proliferation involved in lung development  (ISO)
mesodermal cell differentiation  (ISO)
midbrain development  (ISO)
morphogenesis of embryonic epithelium  (ISO)
negative regulation of cell population proliferation  (ISO)
negative regulation of epithelial cell proliferation  (ISO)
negative regulation of keratinocyte proliferation  (ISO)
negative regulation of mitotic nuclear division  (ISO)
negative regulation of transcription by RNA polymerase II  (ISO)
neuromuscular junction development  (ISO)
odontogenesis  (ISO)
orbitofrontal cortex development  (ISO)
organ growth  (ISO)
otic vesicle formation  (ISO)
outflow tract septum morphogenesis  (ISO)
peptidyl-tyrosine phosphorylation  (ISO)
positive regulation of canonical Wnt signaling pathway  (ISO)
positive regulation of cardiac muscle cell proliferation  (ISO)
positive regulation of cell cycle  (ISO)
positive regulation of cell division  (ISO)
positive regulation of cell population proliferation  (ISO)
positive regulation of epithelial cell proliferation  (ISO)
positive regulation of epithelial cell proliferation involved in lung morphogenesis  (ISO)
positive regulation of ERK1 and ERK2 cascade  (ISO)
positive regulation of gene expression  (ISO)
positive regulation of MAPK cascade  (ISO)
positive regulation of mesenchymal cell proliferation  (ISO)
positive regulation of phospholipase activity  (ISO)
positive regulation of smooth muscle cell proliferation  (ISO)
positive regulation of transcription by RNA polymerase II  (ISO)
positive regulation of Wnt signaling pathway  (ISO)
post-embryonic development  (ISO)
prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis  (ISO)
prostate epithelial cord elongation  (ISO)
prostate gland morphogenesis  (ISO)
protein autophosphorylation  (ISO)
pyramidal neuron development  (ISO)
regulation of cell population proliferation  (ISO)
regulation of epithelial cell proliferation  (ISO)
regulation of ERK1 and ERK2 cascade  (ISO)
regulation of morphogenesis of a branching structure  (ISO)
regulation of smooth muscle cell differentiation  (ISO)
regulation of smoothened signaling pathway  (ISO)
reproductive structure development  (ISO)
response to ethanol  (ISO)
response to lipopolysaccharide  (ISO)
squamous basal epithelial stem cell differentiation involved in prostate gland acinus development  (ISO)
synaptic vesicle transport  (ISO)
ureteric bud development  (ISO)
ventricular cardiac muscle tissue morphogenesis  (ISO)
ventricular zone neuroblast division  (ISO)
wound healing  (ISO)

Cellular Component

Molecular Pathway Annotations     Click to see Annotation Detail View
References


Genomics

Comparative Map Data
Fgfr2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_0049555512,321,190 - 2,427,000 (-)NCBIChiLan1.0ChiLan1.0
FGFR2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl10121,478,334 - 121,598,458 (-)EnsemblGRCh38hg38GRCh38
GRCh38.p13 Ensembl10121,478,332 - 121,598,458 (-)EnsemblGRCh38hg38GRCh38
GRCh3810121,478,330 - 121,598,458 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh3710123,237,844 - 123,357,972 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 3610123,227,845 - 123,347,962 (-)NCBINCBI36hg18NCBI36
Build 3410123,266,837 - 123,347,907NCBI
Celera10116,970,097 - 117,089,799 (-)NCBI
Cytogenetic Map10q26.13NCBI
HuRef10116,868,799 - 116,988,666 (-)NCBIHuRef
CHM1_110123,522,903 - 123,642,701 (-)NCBICHM1_1
Fgfr2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm397129,764,181 - 129,868,538 (-)NCBIGRCm39mm39
GRCm39 Ensembl7129,764,181 - 132,725,079 (-)Ensembl
GRCm387130,162,451 - 130,266,808 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl7130,162,451 - 133,123,350 (-)EnsemblGRCm38mm10GRCm38
MGSCv377137,305,965 - 137,410,322 (-)NCBIGRCm37mm9NCBIm37
MGSCv367129,954,867 - 130,057,411 (-)NCBImm8
Celera7129,989,855 - 130,093,942 (-)NCBICelera
Cytogenetic Map7F3NCBI
Fgfr2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21184,745,418 - 184,850,655 (-)NCBI
Rnor_6.0 Ensembl1200,590,953 - 200,696,928 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.01200,590,951 - 200,696,946 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01207,626,732 - 207,731,841 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41189,482,975 - 189,589,279 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11189,667,865 - 189,734,790 (-)NCBI
Celera1182,362,666 - 182,467,651 (-)NCBICelera
Cytogenetic Map1q37NCBI
FGFR2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.110121,469,735 - 121,588,815 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl10121,469,735 - 121,588,815 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v010118,055,854 - 118,175,440 (-)NCBIMhudiblu_PPA_v0panPan3
FGFR2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12831,303,882 - 31,411,015 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2831,303,894 - 31,411,621 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2831,443,692 - 31,545,836 (-)NCBI
ROS_Cfam_1.02831,838,529 - 31,945,124 (-)NCBI
UMICH_Zoey_3.12831,369,550 - 31,471,773 (-)NCBI
UNSW_CanFamBas_1.02831,390,735 - 31,492,943 (-)NCBI
UU_Cfam_GSD_1.02831,595,945 - 31,698,233 (-)NCBI
Fgfr2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440721314,955,026 - 15,055,733 (+)NCBI
SpeTri2.0NW_00493648610,506,680 - 10,606,272 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
FGFR2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl14131,181,710 - 131,579,703 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.114131,183,095 - 131,285,001 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.214142,500,502 - 142,565,883 (-)NCBISscrofa10.2Sscrofa10.2susScr3
FGFR2
(Chlorocebus sabaeus - African green monkey)
Vervet AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.19114,234,344 - 114,354,736 (-)NCBI
ChlSab1.1 Ensembl9114,234,250 - 114,354,704 (-)Ensembl
Vero_WHO_p1.0NW_02366604875,522,971 - 75,644,166 (-)NCBI
Fgfr2
(Heterocephalus glaber - naked mole-rat)
Molerat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462473725,052,698 - 25,158,346 (+)NCBI


Expression


Sequence


Reference Sequences
RefSeq Acc Id: XM_005412181   ⟹   XP_005412238
RefSeq Status:
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_0049555512,321,190 - 2,427,000 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_005412238 (Get FASTA)   NCBI Sequence Viewer  
Reference Sequences
RefSeq Acc Id: XP_005412238   ⟸   XM_005412181
- Sequence:


Additional Information

Database Acc Id Source(s)
NCBI Gene Fgfr2 ENTREZGENE