Egflam (EGF like, fibronectin type III and laminin G domains) - Rat Genome Database

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Gene: Egflam (EGF like, fibronectin type III and laminin G domains) Chinchilla lanigera
Analyze
Symbol: Egflam
Name: EGF like, fibronectin type III and laminin G domains
RGD ID: 8994315
Description: ENCODES a protein that exhibits glycosaminoglycan binding (ortholog); INVOLVED IN extracellular matrix organization (ortholog); positive regulation of cell-substrate adhesion (ortholog); ASSOCIATED WITH genetic disease (ortholog); High Myopia (ortholog); Neurodevelopmental Disorders (ortholog); FOUND IN basement membrane (ortholog); cell surface (ortholog); extracellular matrix (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: EGF-like, fibronectin type III and laminin G domains; pikachurin
RGD Orthologs
Human
Mouse
Rat
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: ChiLan1.0 - Chinchilla ChiLan1.0 Assembly
Position:
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495542622,856,186 - 23,031,029 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495542622,856,515 - 23,030,517 (+)NCBIChiLan1.0ChiLan1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Transitive Annotation Pipeline Automated assignment of GO, PW and RDO ISO annotations across species
Additional References at PubMed
PMID:22301074  


Genomics

Comparative Map Data
Egflam
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495542622,856,186 - 23,031,029 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495542622,856,515 - 23,030,517 (+)NCBIChiLan1.0ChiLan1.0
EGFLAM
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38538,258,559 - 38,465,480 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl538,258,409 - 38,465,480 (+)EnsemblGRCh38hg38GRCh38
GRCh37538,258,661 - 38,465,582 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36538,294,290 - 38,501,338 (+)NCBINCBI36Build 36hg18NCBI36
Celera538,144,780 - 38,352,160 (+)NCBICelera
Cytogenetic Map5p13.2-p13.1NCBI
HuRef538,210,992 - 38,417,598 (+)NCBIHuRef
CHM1_1538,260,483 - 38,467,502 (+)NCBICHM1_1
T2T-CHM13v2.0538,507,663 - 38,714,549 (+)NCBIT2T-CHM13v2.0
Egflam
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39157,235,598 - 7,428,203 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl157,235,601 - 7,427,876 (-)EnsemblGRCm39 Ensembl
GRCm38157,206,120 - 7,398,744 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl157,206,120 - 7,398,395 (-)EnsemblGRCm38mm10GRCm38
MGSCv37157,156,120 - 7,348,304 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36157,153,335 - 7,345,519 (-)NCBIMGSCv36mm8
Celera157,054,466 - 7,246,274 (-)NCBICelera
Cytogenetic Map15A1NCBI
cM Map153.5NCBI
Egflam
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8258,029,934 - 58,204,010 (-)NCBIGRCr8
mRatBN7.2256,301,945 - 56,476,665 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl256,302,566 - 56,476,298 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx263,406,366 - 63,580,040 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0261,476,948 - 61,650,970 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0256,478,490 - 56,652,163 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0256,503,002 - 56,681,334 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl256,502,807 - 56,679,955 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0276,243,791 - 76,418,618 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4256,493,064 - 56,666,659 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1256,420,993 - 56,594,873 (-)NCBI
Celera251,921,938 - 52,095,667 (-)NCBICelera
Cytogenetic Map2q16NCBI
EGFLAM
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2471,872,765 - 72,084,164 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1570,027,330 - 70,237,797 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0571,909,106 - 72,119,958 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1576,944,890 - 77,155,714 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl576,944,818 - 77,073,380 (-)Ensemblpanpan1.1panPan2
EGFLAM
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1470,391,657 - 70,574,629 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl470,392,330 - 70,575,225 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha470,067,121 - 70,249,572 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0470,908,254 - 71,090,611 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl470,908,281 - 71,090,300 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1470,656,297 - 70,837,561 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0470,769,824 - 70,951,780 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0471,308,421 - 71,490,218 (-)NCBIUU_Cfam_GSD_1.0
Egflam
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024407213227,489,464 - 227,665,015 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365183,706,803 - 3,881,592 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365183,706,818 - 3,882,308 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
EGFLAM
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1623,509,491 - 23,606,924 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11623,402,937 - 23,606,234 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21624,682,042 - 24,903,094 (+)NCBISscrofa10.2Sscrofa10.2susScr3
EGFLAM
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1437,096,097 - 37,297,978 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl437,098,302 - 37,297,968 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366607127,460,741 - 27,660,250 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Egflam
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462475916,488,798 - 16,658,428 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462475916,488,906 - 16,658,332 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSCLAT00000016364   ⟹   ENSCLAP00000016200
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_00495542622,856,186 - 23,031,029 (+)Ensembl
RefSeq Acc Id: ENSCLAT00000016365   ⟹   ENSCLAP00000016201
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_00495542622,856,798 - 23,029,526 (+)Ensembl
RefSeq Acc Id: ENSCLAT00000016366   ⟹   ENSCLAP00000016202
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_00495542622,856,798 - 23,029,526 (+)Ensembl
RefSeq Acc Id: XM_005386224   ⟹   XP_005386281
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_00495542622,856,515 - 23,030,517 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_005386281 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSCLAP00000016200
  ENSCLAP00000016200.1
  ENSCLAP00000016201.1
  ENSCLAP00000016202.1
Reference Protein Sequences
RefSeq Acc Id: XP_005386281   ⟸   XM_005386224
- UniProtKB: A0A8C2VIP1 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSCLAP00000016201   ⟸   ENSCLAT00000016365
RefSeq Acc Id: ENSCLAP00000016200   ⟸   ENSCLAT00000016364
RefSeq Acc Id: ENSCLAP00000016202   ⟸   ENSCLAT00000016366
Protein Domains
EGF-like   Fibronectin type-III   Laminin G


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCLAG00000011146 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCLAT00000016364 ENTREZGENE
  ENSCLAT00000016364.1 UniProtKB/TrEMBL
  ENSCLAT00000016365.1 UniProtKB/TrEMBL
  ENSCLAT00000016366.1 UniProtKB/TrEMBL
Gene3D-CATH 2.60.120.200 UniProtKB/TrEMBL
  2.60.40.10 UniProtKB/TrEMBL
  Laminin UniProtKB/TrEMBL
InterPro ConA-like_dom_sf UniProtKB/TrEMBL
  EGF-like_Ca-bd_dom UniProtKB/TrEMBL
  EGF-like_CS UniProtKB/TrEMBL
  EGF-like_dom UniProtKB/TrEMBL
  FN3_dom UniProtKB/TrEMBL
  FN3_sf UniProtKB/TrEMBL
  Ig-like_fold UniProtKB/TrEMBL
  Laminin_G UniProtKB/TrEMBL
NCBI Gene Egflam ENTREZGENE
PANTHER PIKACHURIN UniProtKB/TrEMBL
  PIKACHURIN-LIKE PROTEIN UniProtKB/TrEMBL
Pfam EGF UniProtKB/TrEMBL
  fn3 UniProtKB/TrEMBL
  hEGF UniProtKB/TrEMBL
  Laminin_G_1 UniProtKB/TrEMBL
  Laminin_G_2 UniProtKB/TrEMBL
PROSITE EGF_1 UniProtKB/TrEMBL
  EGF_2 UniProtKB/TrEMBL
  EGF_3 UniProtKB/TrEMBL
  FN3 UniProtKB/TrEMBL
  LAM_G_DOMAIN UniProtKB/TrEMBL
SMART EGF UniProtKB/TrEMBL
  EGF_CA UniProtKB/TrEMBL
  FN3 UniProtKB/TrEMBL
  LamG UniProtKB/TrEMBL
Superfamily-SCOP SSF49265 UniProtKB/TrEMBL
  SSF49899 UniProtKB/TrEMBL
UniProt A0A8C2VII0_CHILA UniProtKB/TrEMBL
  A0A8C2VIN0_CHILA UniProtKB/TrEMBL
  A0A8C2VIP1 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-08-03 Egflam  EGF like, fibronectin type III and laminin G domains    EGF-like, fibronectin type III and laminin G domains  Symbol and/or name change 5135510 APPROVED