Dhrs7b (dehydrogenase/reductase 7B) - Rat Genome Database

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Gene: Dhrs7b (dehydrogenase/reductase 7B) Chinchilla lanigera
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Symbol: Dhrs7b
Name: dehydrogenase/reductase 7B
RGD ID: 8993695
Description: ENCODES a protein that exhibits DNA-binding transcription factor binding (ortholog); transcription corepressor activity (ortholog); INVOLVED IN adipose tissue development (ortholog); brown fat cell differentiation (ortholog); ether lipid biosynthetic process (ortholog); ASSOCIATED WITH genetic disease (ortholog); FOUND IN membrane (ortholog); nucleus (ortholog); peroxisome (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: dehydrogenase/reductase (SDR family) member 7B; dehydrogenase/reductase SDR family member 7B
RGD Orthologs
Human
Mouse
Rat
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: ChiLan1.0 - Chinchilla ChiLan1.0 Assembly
Position:
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555771,071,775 - 1,121,940 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049555771,071,904 - 1,122,204 (+)NCBIChiLan1.0ChiLan1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Transitive Annotation Pipeline Automated assignment of GO, PW and RDO ISO annotations across species
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Dhrs7b
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555771,071,775 - 1,121,940 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049555771,071,904 - 1,122,204 (+)NCBIChiLan1.0ChiLan1.0
DHRS7B
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381721,126,964 - 21,191,420 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1721,123,364 - 21,193,265 (+)EnsemblGRCh38hg38GRCh38
GRCh371721,030,277 - 21,094,733 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361720,970,850 - 21,035,428 (+)NCBINCBI36Build 36hg18NCBI36
Celera1721,447,631 - 21,512,215 (-)NCBICelera
Cytogenetic Map17p11.2NCBI
HuRef1720,232,340 - 20,297,454 (+)NCBIHuRef
CHM1_11721,039,829 - 21,104,899 (+)NCBICHM1_1
T2T-CHM13v2.01721,068,745 - 21,140,297 (+)NCBIT2T-CHM13v2.0
Dhrs7b
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391160,721,457 - 60,749,249 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1160,721,457 - 60,751,021 (+)EnsemblGRCm39 Ensembl
GRCm381160,830,631 - 60,858,423 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1160,830,631 - 60,860,195 (+)EnsemblGRCm38mm10GRCm38
MGSCv371160,644,133 - 60,671,925 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361160,646,883 - 60,674,341 (+)NCBIMGSCv36mm8
Celera1167,825,089 - 67,834,528 (-)NCBICelera
Cytogenetic Map11B2NCBI
cM Map1137.87NCBI
Dhrs7b
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81046,003,845 - 46,036,498 (+)NCBIGRCr8
mRatBN7.21045,504,344 - 45,537,094 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1045,504,426 - 45,537,076 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1050,205,760 - 50,239,151 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01049,696,146 - 49,729,535 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01045,199,735 - 45,233,124 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01047,065,755 - 47,111,089 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1047,065,850 - 47,111,101 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01046,837,592 - 46,884,565 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41046,971,430 - 47,003,953 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11046,985,052 - 47,017,575 (+)NCBI
Celera1044,758,979 - 44,791,995 (+)NCBICelera
Cytogenetic Map10q22NCBI
DHRS7B
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21950,196,297 - 50,264,246 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11755,064,419 - 55,132,964 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01730,455,933 - 30,520,997 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11735,319,039 - 35,387,106 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1735,317,600 - 35,383,619 (-)Ensemblpanpan1.1panPan2
DHRS7B
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1542,603,027 - 42,666,446 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl542,603,078 - 42,665,673 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha542,741,213 - 42,804,652 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0542,710,747 - 42,774,163 (+)NCBIROS_Cfam_1.0
UMICH_Zoey_3.1542,677,287 - 42,740,753 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0542,624,428 - 42,687,843 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0542,817,219 - 42,880,678 (+)NCBIUU_Cfam_GSD_1.0
Dhrs7b
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440560262,371,158 - 62,412,067 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936741456,465 - 496,121 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936741455,796 - 496,089 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
DHRS7B
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1261,320,730 - 61,350,219 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11261,320,665 - 61,347,542 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
DHRS7B
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11619,238,397 - 19,301,307 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1619,284,743 - 19,301,144 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660591,456,570 - 1,520,627 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Dhrs7b
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248494,858,517 - 4,903,686 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248494,858,496 - 4,905,157 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence


RefSeq Acc Id: ENSCLAT00000001696   ⟹   ENSCLAP00000001653
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_0049555771,071,775 - 1,121,940 (+)Ensembl
RefSeq Acc Id: XM_005413986   ⟹   XP_005414043
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_0049555771,098,660 - 1,122,204 (+)NCBI
Sequence:
RefSeq Acc Id: XM_005413987   ⟹   XP_005414044
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_0049555771,072,013 - 1,122,204 (+)NCBI
Sequence:
RefSeq Acc Id: XM_013509623   ⟹   XP_013365077
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_0049555771,071,904 - 1,122,204 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_005414043 (Get FASTA)   NCBI Sequence Viewer  
  XP_005414044 (Get FASTA)   NCBI Sequence Viewer  
  XP_013365077 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSCLAP00000001653
  ENSCLAP00000001653.1
RefSeq Acc Id: XP_005414043   ⟸   XM_005413986
- Peptide Label: isoform X3
- Sequence:
RefSeq Acc Id: XP_005414044   ⟸   XM_005413987
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_013365077   ⟸   XM_013509623
- Peptide Label: isoform X2
- UniProtKB: A0A8C2YIR0 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSCLAP00000001653   ⟸   ENSCLAT00000001696


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCLAG00000001235 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCLAT00000001696 ENTREZGENE
  ENSCLAT00000001696.1 UniProtKB/TrEMBL
Gene3D-CATH NAD(P)-binding Rossmann-like Domain UniProtKB/TrEMBL
InterPro NAD(P)-bd_dom_sf UniProtKB/TrEMBL
  Sc_DH/Rdtase_CS UniProtKB/TrEMBL
  SDR_fam UniProtKB/TrEMBL
NCBI Gene Dhrs7b ENTREZGENE
PANTHER DEHYDROGENASE/REDUCTASE SDR FAMILY MEMBER 7B UniProtKB/TrEMBL
  DEHYDROGENASE/REDUCTASE SDR FAMILY MEMBER 7B UniProtKB/TrEMBL
Pfam adh_short UniProtKB/TrEMBL
PIRSF 11-beta-HSD1 UniProtKB/TrEMBL
PRINTS GDHRDH UniProtKB/TrEMBL
  SDRFAMILY UniProtKB/TrEMBL
PROSITE ADH_SHORT UniProtKB/TrEMBL
  PROKAR_LIPOPROTEIN UniProtKB/TrEMBL
Superfamily-SCOP SSF51735 UniProtKB/TrEMBL
UniProt A0A8C2YIR0 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-08-03 Dhrs7b  dehydrogenase/reductase 7B    dehydrogenase/reductase (SDR family) member 7B  Symbol and/or name change 5135510 APPROVED