Ube2e1 (ubiquitin conjugating enzyme E2 E1)

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Gene: Ube2e1 (ubiquitin conjugating enzyme E2 E1) Chinchilla lanigera

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Symbol:

Ube2e1

Name:

ubiquitin conjugating enzyme E2 E1

RGD ID:

8993479

Description:

ENCODES a protein that exhibits ISG15 transferase activity (ortholog); ubiquitin conjugating enzyme activity (ortholog); ubiquitin-protein transferase activity (ortholog); INVOLVED IN ISG15-protein conjugation (ortholog); positive regulation of transcription by RNA polymerase II (ortholog); protein K48-linked ubiquitination (ortholog); ASSOCIATED WITH Arsenic Poisoning (ortholog); juvenile rheumatoid arthritis (ortholog); skin disease (ortholog); FOUND IN nucleus (ortholog); ubiquitin ligase complex (ortholog)

Type:

protein-coding

RefSeq Status:

MODEL

Previously known as:

ubiquitin-conjugating enzyme E2 E1; ubiquitin-conjugating enzyme E2E 1

RGD Orthologs

Alliance Orthologs

More Info

more info ...

Latest Assembly:

ChiLan1.0 - Chinchilla ChiLan1.0 Assembly

Position:

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955430	15,648,476 - 15,734,767 (+)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955430	15,648,736 - 15,734,767 (+)	NCBI	ChiLan1.0	ChiLan1.0

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

Arsenic Poisoning (ISO)

juvenile rheumatoid arthritis (ISO)

skin disease (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

ISG15-protein conjugation (ISO)

positive regulation of transcription by RNA polymerase II (ISO)

protein K48-linked ubiquitination (ISO)

protein monoubiquitination (ISO)

protein polyubiquitination (ISO)

protein ubiquitination (ISO)

Cellular Component

nucleus (ISO)

ubiquitin ligase complex (ISO)

Molecular Function

ISG15 transferase activity (ISO)

protein binding (ISO)

ubiquitin conjugating enzyme activity (ISO)

ubiquitin-protein transferase activity (ISO)

References

References - curated

#	Reference Title	Reference Citation
1.	Transitive Annotation Pipeline	Automated assignment of GO, PW and RDO ISO annotations across species

Additional References at PubMed

PMID:30032202

Genomics

Comparative Map Data

Ube2e1
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955430	15,648,476 - 15,734,767 (+)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955430	15,648,736 - 15,734,767 (+)	NCBI	ChiLan1.0	ChiLan1.0

UBE2E1
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	3	23,805,955 - 23,891,640 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	3	23,805,955 - 23,891,640 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	3	23,847,446 - 23,933,131 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	3	23,822,443 - 23,907,811 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	3	23,822,442 - 23,907,810	NCBI
Celera	3	23,783,561 - 23,868,992 (+)	NCBI		Celera
Cytogenetic Map	3	p24.2	NCBI
HuRef	3	23,793,438 - 23,879,219 (+)	NCBI		HuRef
CHM1_1	3	23,799,158 - 23,884,951 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	3	23,810,731 - 23,896,417 (+)	NCBI		T2T-CHM13v2.0

Ube2e1
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	14	4,137,852 - 4,186,967 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	14	4,137,837 - 4,186,974 (+)	Ensembl		GRCm39 Ensembl
GRCm38	14	18,282,726 - 18,332,004 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	14	18,282,722 - 18,331,859 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	14	19,115,243 - 19,164,358 (-)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	14	17,075,847 - 17,124,962 (-)	NCBI		MGSCv36	mm8
Celera	14	13,974,286 - 14,024,829 (-)	NCBI		Celera
Cytogenetic Map	14	A1	NCBI
cM Map	14	7.08	NCBI

Ube2e1
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	15	9,870,528 - 9,924,194 (+)	NCBI		GRCr8
mRatBN7.2	15	7,439,751 - 7,493,410 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	15	7,439,759 - 7,493,400 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	15	9,586,863 - 9,639,117 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	15	10,499,658 - 10,551,914 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	15	8,800,075 - 8,852,332 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	15	8,124,869 - 8,178,252 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	15	8,125,526 - 8,177,781 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	15	12,188,488 - 12,240,293 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
Celera	15	7,495,553 - 7,546,701 (+)	NCBI		Celera
Cytogenetic Map	15	p16	NCBI

UBE2E1
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	2	23,768,360 - 23,852,050 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	3	23,773,125 - 23,856,807 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	3	23,719,632 - 23,803,302 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	3	24,045,758 - 24,127,826 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	3	24,045,747 - 24,127,820 (+)	Ensembl	panpan1.1		panPan2

UBE2E1
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	23	19,863,136 - 19,937,272 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	23	19,863,253 - 19,937,247 (-)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	23	19,861,218 - 19,936,689 (-)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	23	20,176,162 - 20,251,667 (-)	NCBI		ROS_Cfam_1.0
UMICH_Zoey_3.1	23	19,985,486 - 20,061,512 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	23	20,094,687 - 20,170,077 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	23	20,203,814 - 20,279,270 (-)	NCBI		UU_Cfam_GSD_1.0

Ube2e1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024405118	182,348,783 - 182,418,938 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936473	15,487,014 - 15,557,513 (+)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936473	15,487,341 - 15,557,516 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

LOC102160336
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	13	10,605,503 - 10,683,816 (+)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	13	10,605,837 - 10,683,819 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	13	12,058,613 - 12,131,848 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

UBE2E1
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	15	68,483,247 - 68,566,645 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	15	68,484,589 - 68,568,987 (+)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666041	41,607,680 - 41,690,874 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Sequence

Nucleotide Sequences


RefSeq Transcripts	XM_005387476	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AGCD01029608	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AGCD01029609	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AGCD01029610	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AGCD01029611	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AGCD01029612	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AGCD01029613	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	GBDF01083427	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSCLAT00000020201 ⟹ ENSCLAP00000020008

Type:

CODING

Position:

Chinchilla Assembly	Chr	Position (strand)	Source
ChiLan1.0 Ensembl	NW_004955430	15,648,476 - 15,734,767 (+)	Ensembl

RefSeq Acc Id:

XM_005387476 ⟹ XP_005387533

Type:

CODING

Position:

Chinchilla Assembly	Chr	Position (strand)	Source
ChiLan1.0	NW_004955430	15,648,736 - 15,734,767 (+)	NCBI

Sequence:

show sequence

GAGGCCGGGTGGGGAGCCCGGGGGGCGAGGGAGGGGCTGCCCGCTGCGTCCCCTACTTGGGGCC
GGAGAGAAACAAACAAGCCGTGTCCGCTCTGCTGAGCCTTGCTGGGCCTGGAGACTTTGGGAAG
AGGGTGCAGAGCGGTGGGCGCAGCGGTGCCCTCCAGACGGAACCCGAGTTCCGTATTTACACTC
CCTGCAGGGCCTTGTGTTTCTGTTTTGTTTCCCTCCCCCTGCAGGGGCTGTTTGCGGGGTGGGG
TGGGGGGTTCGCTATGTCGGATGACGATTCGAGGGCAAGCACCAGCTCCTCCTCATCTTCGTCC
TCCAACCAGCAAACCGAGAAAGAAACAAACACCCCCAAGAAGAAGGAGAGTAAAGTCAGCATGA
GCAAAAACTCCAAGCTCCTCTCCACCAGCGCCAAGAGGATTCAGAAGGAGCTGGCAGACATCAC
TCTAGACCCTCCGCCGAACTGCAGTGCTGGGCCTAAAGGTGACAACATCTATGAGTGGAGATCT
ACCATTCTAGGACCTCCAGGATCTGTGTATGAAGGTGGTGTATTCTTCCTGGATATCACTTTCA
CTCCAGAATATCCCTTCAAACCTCCAAAGGTTACATTTCGGACAAGAATCTATCACTGTAATAT
TAACAGTCAAGGAGTTATTTGCTTGGATATATTGAAAGATAATTGGAGTCCAGCACTAACTATT
TCTAAAGTCCTCCTTTCTATCTGCTCACTTCTTACAGACTGTAATCCTGCTGACCCTTTGGTGG
GAAGTATTGCCACTCAGTATATGACCAACAGAGCAGAACATGACAGAATGGCCAGACAGTGGAC
CAAGAGATACGCTACATAAATTGAATTGCGTTTTCACAATTCCTACATTATTTGTCTGTCACAG
AAGAGAGCTGCTTATGATTTTGAAGGGGCAGGGGAGGGTGGGAGTTGGTAAAGAGTAGGGTATT
TCTATAACAGATATTATTCAGTTTTATTTCCTAAGATTTTGTTGTAACTTAAGGTATCTTGCTA
CAGTAGACAAAATTGGTAATAGCAACTTTTAAAACTCATTAGTTCTACAATATTGGCTGAAATG
TAGTATGGAAAAGAATGTACACTTAGATACTTGGATTCAGTTGCTTGTAGTATGTAATTTTTAA
ACAGCTTAATTTTGTACAGGTTACACACATGGCCATTTATGTAAAGTCGTAAGATGGCACACTT
TTTGTTTTAAAAATTGGAGTTTGTTTGTCCCTTCTTGGAAGGGAACATTGATATTTAACAGAGT
TTTTAAGATTGTCATCTCATATAAATATATATATATATAAATATATATATAAAATAGATGTGGC
TATAAGACACCATGTAGGAAATGAGTAGTTAATGTATTTTATTTTATATGGAATTTACTTTAAA
GGTTTGAATCAGAACCTGTGAGAACCTGTAGTGAAATACCTTAAGCTGTTCAGTGTAAGGCGTG
GAATAGGAGTCACTCTGGATTGGTTACATGTTGTAGACTTCTTACGTCTGCATTTGTTACTGTG
CTAATAAACCATATTAAAAACAATCAA

hide sequence

Protein Sequences


Protein RefSeqs	XP_005387533	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSCLAP00000020008
	ENSCLAP00000020008.1

RefSeq Acc Id:	XP_005387533 ⟸ XM_005387476
- UniProtKB:	A0A8C2VST8 (UniProtKB/TrEMBL)
- Sequence:	show sequence MSDDDSRASTSSSSSSSSNQQTEKETNTPKKKESKVSMSKNSKLLSTSAKRIQKELADITLDPP PNCSAGPKGDNIYEWRSTILGPPGSVYEGGVFFLDITFTPEYPFKPPKVTFRTRIYHCNINSQG VICLDILKDNWSPALTISKVLLSICSLLTDCNPADPLVGSIATQYMTNRAEHDRMARQWTKRYA T hide sequence

Ensembl Acc Id:

ENSCLAP00000020008 ⟸ ENSCLAT00000020201

Protein Domains

UBC core

Additional Information

External Database Links

Database	Acc Id	Source(s)
Ensembl Genes	ENSCLAG00000013711	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSCLAT00000020201	ENTREZGENE
	ENSCLAT00000020201.1	UniProtKB/TrEMBL
Gene3D-CATH	3.10.110.10	UniProtKB/TrEMBL
InterPro	UBQ-conjugat_E2	UniProtKB/TrEMBL
	UBQ-conjugating_AS	UniProtKB/TrEMBL
	UBQ-conjugating_enzyme/RWD	UniProtKB/TrEMBL
NCBI Gene	Ube2e1	ENTREZGENE
PANTHER	UBIQUITIN-CONJUGATING ENZYME E2	UniProtKB/TrEMBL
	UBIQUITIN-CONJUGATING ENZYME E2 E1	UniProtKB/TrEMBL
Pfam	UQ_con	UniProtKB/TrEMBL
PROSITE	UBC_1	UniProtKB/TrEMBL
	UBC_2	UniProtKB/TrEMBL
SMART	UBCc	UniProtKB/TrEMBL
Superfamily-SCOP	SSF54495	UniProtKB/TrEMBL
UniProt	A0A8C2VST8	ENTREZGENE, UniProtKB/TrEMBL

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2016-08-03	Ube2e1	ubiquitin conjugating enzyme E2 E1		ubiquitin-conjugating enzyme E2E 1	Symbol and/or name change	5135510	APPROVED

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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