Nfe2l3 (NFE2 like bZIP transcription factor 3) - Rat Genome Database

Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models   new Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Gene: Nfe2l3 (NFE2 like bZIP transcription factor 3) Chinchilla lanigera
Analyze
Symbol: Nfe2l3
Name: NFE2 like bZIP transcription factor 3 (Ensembl:nuclear factor, erythroid 2 like 3)
RGD ID: 8992920
Description: ENCODES a protein that exhibits DNA-binding transcription repressor activity, RNA polymerase II-specific (ortholog); RNA polymerase II cis-regulatory region sequence-specific DNA binding (ortholog); INVOLVED IN negative regulation of transcription by RNA polymerase II (ortholog); ASSOCIATED WITH genetic disease (ortholog); keratoconus (ortholog); pleomorphic xanthoastrocytoma (ortholog); FOUND IN RNA polymerase II transcription regulator complex (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: nuclear factor (erythroid-derived 2)-like 3; nuclear factor erythroid 2-related factor 3; nuclear factor, erythroid 2 like 3; nuclear factor, erythroid 2-like 3
RGD Orthologs
Human
Mouse
Rat
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: ChiLan1.0 - Chinchilla ChiLan1.0 Assembly
Position:
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541027,998,817 - 28,029,487 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495541027,999,098 - 28,031,941 (+)NCBIChiLan1.0ChiLan1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

References

References - curated
# Reference Title Reference Citation
1. Transitive Annotation Pipeline Automated assignment of GO, PW and RDO ISO annotations across species
Additional References at PubMed
PMID:30032202  


Genomics

Comparative Map Data
Nfe2l3
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541027,998,817 - 28,029,487 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495541027,999,098 - 28,031,941 (+)NCBIChiLan1.0ChiLan1.0
NFE2L3
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38726,152,198 - 26,187,137 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl726,152,198 - 26,187,137 (+)EnsemblGRCh38hg38GRCh38
GRCh37726,191,818 - 26,226,757 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36726,158,385 - 26,192,432 (+)NCBINCBI36Build 36hg18NCBI36
Build 34725,965,099 - 25,999,147NCBI
Celera726,180,718 - 26,215,742 (+)NCBICelera
Cytogenetic Map7p15.2NCBI
HuRef726,073,761 - 26,108,671 (+)NCBIHuRef
CHM1_1726,184,957 - 26,219,983 (+)NCBICHM1_1
T2T-CHM13v2.0726,287,764 - 26,322,815 (+)NCBIT2T-CHM13v2.0
CRA_TCAGchr7v2726,242,879 - 26,277,907 (+)NCBI
Nfe2l3
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39651,409,649 - 51,435,752 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl651,409,650 - 51,435,748 (+)EnsemblGRCm39 Ensembl
GRCm38651,432,669 - 51,458,772 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl651,432,670 - 51,458,768 (+)EnsemblGRCm38mm10GRCm38
MGSCv37651,382,669 - 51,408,767 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36651,362,253 - 51,388,351 (+)NCBIMGSCv36mm8
Celera651,949,723 - 51,976,502 (+)NCBICelera
Cytogenetic Map6B3NCBI
cM Map624.84NCBI
Nfe2l3
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8481,837,404 - 81,865,258 (+)NCBIGRCr8
mRatBN7.2480,506,756 - 80,534,629 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl480,506,756 - 80,534,629 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx485,731,104 - 85,758,890 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0481,506,496 - 81,534,284 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0479,945,946 - 79,973,710 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0481,205,214 - 81,233,068 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl481,205,404 - 81,232,813 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.04145,871,407 - 145,901,537 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4479,668,259 - 79,695,648NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera475,407,547 - 75,435,350 (+)NCBICelera
Cytogenetic Map4q24NCBI
NFE2L3
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2630,982,110 - 31,017,136 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1779,306,843 - 79,341,862 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0726,798,049 - 26,833,069 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1726,402,455 - 26,436,432 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl726,402,451 - 26,435,056 (+)Ensemblpanpan1.1panPan2
NFE2L3
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11439,456,765 - 39,495,613 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1439,460,428 - 39,495,169 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1438,951,184 - 38,986,410 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01439,398,950 - 39,434,305 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1439,398,691 - 39,433,850 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11439,514,087 - 39,549,351 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01439,201,224 - 39,236,095 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01439,551,958 - 39,587,164 (+)NCBIUU_Cfam_GSD_1.0
Nfe2l3
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440511883,730,711 - 83,756,213 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049364782,942,398 - 2,967,816 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049364782,942,536 - 2,967,930 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
NFE2L3
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1846,217,517 - 46,250,256 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11846,213,392 - 46,250,309 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21850,992,633 - 51,025,440 (-)NCBISscrofa10.2Sscrofa10.2susScr3
NFE2L3
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12132,180,799 - 32,211,662 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2132,182,133 - 32,211,459 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604272,478,464 - 72,509,217 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Nfe2l3
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247394,355,899 - 4,386,749 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247394,355,768 - 4,386,834 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSCLAT00000008566   ⟹   ENSCLAP00000008439
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_00495541027,998,817 - 28,029,487 (+)Ensembl
RefSeq Acc Id: XM_005377433   ⟹   XP_005377490
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_00495541027,999,098 - 28,031,941 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_005377490 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSCLAP00000008439
  ENSCLAP00000008439.1
Reference Protein Sequences
RefSeq Acc Id: XP_005377490   ⟸   XM_005377433
- UniProtKB: A0A8C2V6V8 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSCLAP00000008439   ⟸   ENSCLAT00000008566
Protein Domains
bZIP


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCLAG00000005908 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCLAT00000008566 ENTREZGENE
  ENSCLAT00000008566.1 UniProtKB/TrEMBL
Gene3D-CATH Transcription factor, Skn-1-like, DNA-binding domain UniProtKB/TrEMBL
InterPro bZIP UniProtKB/TrEMBL
  bZIP_Maf UniProtKB/TrEMBL
  bZIP_sf UniProtKB/TrEMBL
  NFE2-like UniProtKB/TrEMBL
  TF_DNA-bd_sf UniProtKB/TrEMBL
NCBI Gene Nfe2l3 ENTREZGENE
PANTHER NUCLEAR FACTOR ERYTHROID 2-RELATED FACTOR UniProtKB/TrEMBL
  PTHR24411:SF8 UniProtKB/TrEMBL
Pfam bZIP_Maf UniProtKB/TrEMBL
PROSITE BZIP UniProtKB/TrEMBL
  BZIP_BASIC UniProtKB/TrEMBL
SMART BRLZ UniProtKB/TrEMBL
Superfamily-SCOP SSF47454 UniProtKB/TrEMBL
  SSF57959 UniProtKB/TrEMBL
UniProt A0A8C2V6V8 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2021-10-05 Nfe2l3  NFE2 like bZIP transcription factor 3  Nfe2l3  nuclear factor, erythroid 2 like 3  Symbol and/or name change 5135510 APPROVED
2016-08-16 Nfe2l3  nuclear factor, erythroid 2 like 3    nuclear factor, erythroid 2-like 3  Symbol and/or name change 5135510 APPROVED
2015-08-25 Nfe2l3  nuclear factor, erythroid 2-like 3    nuclear factor (erythroid-derived 2)-like 3  Symbol and/or name change 5135510 APPROVED