LOC102026028 (cytochrome P450 2E1) - Rat Genome Database
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Gene: LOC102026028 (cytochrome P450 2E1) Chinchilla lanigera
Analyze
Symbol: LOC102026028
Name: cytochrome P450 2E1
RGD ID: 8989701
Description: ENCODES a protein that exhibits 4-nitrophenol 2-monooxygenase activity (ortholog); enzyme binding (ortholog); heme binding (ortholog); INVOLVED IN 4-nitrophenol metabolic process (ortholog); drug metabolic process (ortholog); heterocycle metabolic process (ortholog); PARTICIPATES IN acetylsalicylic acid pharmacodynamics pathway; antipyrine drug pathway; arachidonic acid metabolic pathway; ASSOCIATED WITH acoustic neuroma (ortholog); acute kidney failure (ortholog); acute lymphoblastic leukemia (ortholog); FOUND IN endoplasmic reticulum (ortholog); endoplasmic reticulum membrane (ortholog); Golgi membrane (ortholog)
Type: protein-coding
RefSeq Status: MODEL
RGD Orthologs
Human
Mouse
Rat
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: ChiLan1.0 - Chinchilla ChiLan1.0 Assembly
Position:
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555076,289,576 - 6,304,193 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049555076,293,162 - 6,303,255 (-)NCBIChiLan1.0ChiLan1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View
acoustic neuroma  (ISO)
acute kidney failure  (ISO)
acute lymphoblastic leukemia  (ISO)
adenocarcinoma  (ISO)
alcohol use disorder  (ISO)
Alcoholic Fatty Liver  (ISO)
alcoholic liver cirrhosis  (ISO)
Alcoholic Liver Diseases  (ISO)
amenorrhea  (ISO)
asbestosis  (ISO)
asthma  (ISO)
Binge Drinking  (ISO)
Cardiomegaly  (ISO)
Chemical and Drug Induced Liver Injury  (ISO)
Chronic Bronchitis  (ISO)
chronic obstructive pulmonary disease  (ISO)
colon cancer  (ISO)
colorectal cancer  (ISO)
Drug Eruptions  (ISO)
drug-induced hepatitis  (ISO)
Drug-Related Side Effects and Adverse Reactions  (ISO)
Experimental Diabetes Mellitus  (ISO)
Experimental Liver Neoplasms  (ISO)
extrinsic allergic alveolitis  (ISO)
familial hyperlipidemia  (ISO)
fatty liver disease  (ISO)
hepatocellular adenoma  (ISO)
hepatocellular carcinoma  (ISO)
Human Viral Hepatitis  (ISO)
intrahepatic cholestasis  (ISO)
liver disease  (ISO)
Liver Injury  (ISO)
Liver Neoplasms  (ISO)
lung disease  (ISO)
Lung Neoplasms  (ISO)
lung non-small cell carcinoma  (ISO)
malignant glioma  (ISO)
mental depression  (ISO)
Micronuclei, Chromosome-Defective  (ISO)
middle cerebral artery infarction  (ISO)
morbid obesity  (ISO)
nasopharynx carcinoma  (ISO)
Necrosis  (ISO)
Neoplasm Invasiveness  (ISO)
non-alcoholic fatty liver disease  (ISO)
non-Hodgkin lymphoma  (ISO)
obesity  (ISO)
oral cavity cancer  (ISO)
oral squamous cell carcinoma  (ISO)
Parkinson's disease  (ISO)
Patent Ductus Venosus  (ISO)
pneumonia  (ISO)
Prostatic Neoplasms  (ISO)
Reperfusion Injury  (ISO)
Sepsis  (ISO)
stomach cancer  (ISO)
Testicular Injury  (ISO)
type 1 diabetes mellitus  (ISO)
type 2 diabetes mellitus  (ISO)

Molecular Pathway Annotations     Click to see Annotation Detail View
acetylsalicylic acid pharmacodynamics pathway  (ISO)
antipyrine drug pathway  (ISO)
arachidonic acid metabolic pathway  (ISO)
caffeine pharmacokinetics pathway  (ISO)
celecoxib pharmacodynamics pathway  (ISO)
diclofenac pharmacodynamics pathway  (ISO)
diflunisal pharmacodynamics pathway  (ISO)
disulfiram pharmacodynamics pathway  (ISO)
etodolac pharmacodynamics pathway  (ISO)
felbamate pharmacokinetics pathway  (ISO)
fenoprofen pharmacodynamics pathway  (ISO)
flurbiprofen pharmacodynamics pathway  (ISO)
ibuprofen pharmacodynamics pathway  (ISO)
indometacin pharmacodynamics pathway  (ISO)
indometacin pharmacodynamics pathway  (ISO)
ketoprofen pharmacodynamics pathway  (ISO)
ketorolac pharmacodynamics pathway  (ISO)
leukotriene C4 synthase deficiency pathway  (ISO)
lornoxicam pharmacodynamics pathway  (ISO)
magnesium salicylate pharmacodynamics pathway  (ISO)
mefenamic acid pharmacodynamics pathway  (ISO)
meloxicam pharmacodynamics pathway  (ISO)
nabumetone pharmacodynamics pathway  (ISO)
naproxen pharmacodynamics pathway  (ISO)
paracetamol drug pathway  (ISO)
paracetamol pharmacokinetics pathway  (ISO)
paracetamol response pathway  (ISO)
phenytoin pharmacodynamics pathway  (ISO)
piroxicam pharmacodynamics pathway  (ISO)
salicylic acid pharmacodynamics pathway  (ISO)
sodium salicylate pharmacodynamics pathway  (ISO)
sulindac pharmacodynamics pathway  (ISO)
tenoxicam pharmacodynamics pathway  (ISO)
tiaprofenic acid pharmacodynamics pathway  (ISO)
tolmetin pharmacodynamics pathway  (ISO)
valdecoxib pharmacodynamics pathway  (ISO)

References


Genomics

Comparative Map Data
LOC102026028
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555076,289,576 - 6,304,193 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049555076,293,162 - 6,303,255 (-)NCBIChiLan1.0ChiLan1.0
CYP2E1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl10133,520,406 - 133,561,220 (+)EnsemblGRCh38hg38GRCh38
GRCh3810133,527,363 - 133,539,123 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh3710135,340,300 - 135,352,627 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 3610135,190,857 - 135,202,610 (+)NCBINCBI36hg18NCBI36
Build 3410135,229,747 - 135,241,501NCBI
Celera10128,168,529 - 128,180,282 (-)NCBI
Cytogenetic Map10q26.3NCBI
HuRef10128,882,691 - 128,894,624 (+)NCBIHuRef
CHM1_110135,620,490 - 135,632,188 (+)NCBICHM1_1
Cyp2e1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm397140,343,732 - 140,354,903 (+)NCBIGRCm39mm39
GRCm387140,763,819 - 140,774,990 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl7140,763,739 - 140,774,987 (+)EnsemblGRCm38mm10GRCm38
MGSCv377147,949,731 - 147,960,880 (+)NCBIGRCm37mm9NCBIm37
MGSCv367140,615,152 - 140,626,301 (+)NCBImm8
Celera7140,556,087 - 140,567,236 (+)NCBICelera
Cytogenetic Map7F4NCBI
cM Map785.94NCBI
Cyp2e1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01213,511,892 - 213,522,195 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1213,511,874 - 213,535,542 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01220,405,975 - 220,416,727 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41200,918,521 - 200,928,919 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11201,068,525 - 201,078,911 (+)NCBI
Celera1193,484,404 - 193,494,772 (+)NCBICelera
Cytogenetic Map1q41NCBI
CYP2E1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.110134,839,025 - 134,852,053 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl10134,839,025 - 134,852,719 (+)Ensemblpanpan1.1panPan2
CYP2E1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1 Ensembl2841,035,025 - 41,122,754 (+)EnsemblCanFam3.1canFam3CanFam3.1
CanFam3.12841,079,164 - 41,089,188 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
LOC101973029
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
SpeTri2.0NW_00493648619,691,822 - 19,702,684 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
CYP2E1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl14141,690,426 - 141,736,818 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.114141,690,737 - 141,703,078 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.214153,478,051 - 153,490,404 (+)NCBISscrofa10.2Sscrofa10.2susScr3
CYP2E1
(Chlorocebus sabaeus - African green monkey)
Vervet AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1 Ensembl2653,390,089 - 53,404,211 (+)Ensembl
ChlSab1.12653,390,054 - 53,403,309 (+)NCBI
LOC101722366
(Heterocephalus glaber - naked mole-rat)
Molerat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462473712,335,733 - 12,345,278 (-)NCBI


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSCLAT00000004600   ⟹   ENSCLAP00000004515
RefSeq Status:
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_0049555076,289,576 - 6,304,193 (-)Ensembl
RefSeq Acc Id: ENSCLAT00000004601   ⟹   ENSCLAP00000004516
RefSeq Status:
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_0049555076,293,980 - 6,303,216 (-)Ensembl
RefSeq Acc Id: ENSCLAT00000004602   ⟹   ENSCLAP00000004517
RefSeq Status:
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_0049555076,293,980 - 6,303,216 (-)Ensembl
RefSeq Acc Id: XM_005407704   ⟹   XP_005407761
RefSeq Status:
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_0049555076,293,162 - 6,303,255 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_005407761 (Get FASTA)   NCBI Sequence Viewer  
Reference Sequences
RefSeq Acc Id: XP_005407761   ⟸   XM_005407704
- Sequence:
RefSeq Acc Id: ENSCLAP00000004517   ⟸   ENSCLAT00000004602
RefSeq Acc Id: ENSCLAP00000004515   ⟸   ENSCLAT00000004600
RefSeq Acc Id: ENSCLAP00000004516   ⟸   ENSCLAT00000004601


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCLAG00000003214 Ensembl, ENTREZGENE
Ensembl Protein ENSCLAP00000004515 ENTREZGENE
Ensembl Transcript ENSCLAT00000004600 ENTREZGENE
NCBI Gene LOC102026028 ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2015-08-25 LOC102026028  cytochrome P450 2E1    cytochrome P450 2E1-like  Symbol and/or name change 5135510 APPROVED