Jam3 (junctional adhesion molecule 3) - Rat Genome Database

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Gene: Jam3 (junctional adhesion molecule 3) Chinchilla lanigera
Analyze
Symbol: Jam3
Name: junctional adhesion molecule 3
RGD ID: 8987388
Description: ENCODES a protein that exhibits cell-cell adhesion mediator activity (ortholog); identical protein binding (ortholog); integrin binding (ortholog); INVOLVED IN adaptive immune response (ortholog); adherens junction assembly (ortholog); angiogenesis (ortholog); ASSOCIATED WITH allergic contact dermatitis (ortholog); autism spectrum disorder (ortholog); Carcinoma, Lewis Lung (ortholog); FOUND IN bicellular tight junction (ortholog); cell-cell contact zone (ortholog); cell-cell junction (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: junctional adhesion molecule C
RGD Orthologs
Human
Mouse
Rat
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: ChiLan1.0 - Chinchilla ChiLan1.0 Assembly
Position:
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541234,901,681 - 34,967,394 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495541234,901,850 - 34,967,394 (+)NCBIChiLan1.0ChiLan1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Transitive Annotation Pipeline Automated assignment of GO, PW and RDO ISO annotations across species
2. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
Additional References at PubMed
PMID:30032202  


Genomics

Comparative Map Data
Jam3
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541234,901,681 - 34,967,394 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495541234,901,850 - 34,967,394 (+)NCBIChiLan1.0ChiLan1.0
JAM3
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh3811134,069,072 - 134,152,001 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl11134,069,071 - 134,152,001 (+)EnsemblGRCh38hg38GRCh38
GRCh3711133,938,967 - 134,021,896 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 3611133,444,030 - 133,526,861 (+)NCBINCBI36Build 36hg18NCBI36
Build 3411133,444,029 - 133,526,858NCBI
Celera11131,112,218 - 131,194,832 (+)NCBICelera
Cytogenetic Map11q25NCBI
HuRef11129,893,248 - 129,976,188 (+)NCBIHuRef
CHM1_111133,826,755 - 133,908,474 (+)NCBICHM1_1
T2T-CHM13v2.011134,112,013 - 134,194,140 (+)NCBIT2T-CHM13v2.0
Jam3
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39927,008,680 - 27,066,739 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl927,008,680 - 27,066,717 (-)EnsemblGRCm39 Ensembl
GRCm38927,097,384 - 27,155,421 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl927,097,384 - 27,155,421 (-)EnsemblGRCm38mm10GRCm38
MGSCv37926,904,969 - 26,962,965 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36926,846,830 - 26,904,826 (-)NCBIMGSCv36mm8
Celera924,355,390 - 24,413,352 (-)NCBICelera
Cytogenetic Map9A4NCBI
cM Map912.27NCBI
Jam3
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8833,767,606 - 33,828,451 (-)NCBIGRCr8
mRatBN7.2825,508,461 - 25,569,306 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl825,507,057 - 25,569,355 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx829,550,421 - 29,611,261 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0827,844,708 - 27,905,552 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0825,724,719 - 25,785,571 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0828,147,110 - 28,208,466 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl828,147,111 - 28,208,466 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0828,166,275 - 28,227,631 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4826,697,127 - 26,758,579 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1826,697,127 - 26,758,579 (-)NCBI
Celera826,995,820 - 27,056,659 (-)NCBICelera
Cytogenetic Map8q13NCBI
JAM3
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v29134,787,560 - 134,878,062 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan111135,892,480 - 135,977,406 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v011128,916,024 - 129,006,497 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.111132,783,580 - 132,864,657 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl11132,783,580 - 132,864,657 (+)Ensemblpanpan1.1panPan2
JAM3
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.151,082,619 - 1,165,188 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl51,084,560 - 1,165,121 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha51,202,269 - 1,285,185 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.051,038,590 - 1,121,616 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl51,038,594 - 1,121,627 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.151,071,730 - 1,155,064 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.051,072,117 - 1,155,128 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.051,109,856 - 1,192,622 (-)NCBIUU_Cfam_GSD_1.0
Jam3
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024404947115,840,860 - 115,913,401 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366841,692,089 - 1,762,087 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049366841,689,594 - 1,762,066 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
JAM3
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl960,613,400 - 60,738,924 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1960,629,245 - 60,738,979 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2967,205,386 - 67,284,770 (+)NCBISscrofa10.2Sscrofa10.2susScr3
JAM3
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11125,136,963 - 125,211,424 (+)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_023666043831,362 - 904,938 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Jam3
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248128,643,921 - 8,707,351 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248128,644,002 - 8,707,257 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSCLAT00000025464   ⟹   ENSCLAP00000025218
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_00495541234,901,681 - 34,967,394 (+)Ensembl
RefSeq Acc Id: XM_005378586   ⟹   XP_005378643
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_00495541234,901,850 - 34,967,394 (+)NCBI
Sequence:
RefSeq Acc Id: XM_005378587   ⟹   XP_005378644
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_00495541234,901,943 - 34,967,394 (+)NCBI
Sequence:
RefSeq Acc Id: XM_013511148   ⟹   XP_013366602
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_00495541234,902,742 - 34,967,394 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_005378643 (Get FASTA)   NCBI Sequence Viewer  
  XP_005378644 (Get FASTA)   NCBI Sequence Viewer  
  XP_013366602 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSCLAP00000025218
  ENSCLAP00000025218.1
Reference Protein Sequences
RefSeq Acc Id: XP_005378643   ⟸   XM_005378586
- Peptide Label: isoform X2
- UniProtKB: A0A8C2W5M3 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_005378644   ⟸   XM_005378587
- Peptide Label: isoform X1
- UniProtKB: A0A8C2W5M3 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_013366602   ⟸   XM_013511148
- Peptide Label: isoform X3
- UniProtKB: A0A8C2W5M3 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSCLAP00000025218   ⟸   ENSCLAT00000025464
Protein Domains
Ig-like


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCLAG00000017320 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCLAT00000025464 ENTREZGENE
  ENSCLAT00000025464.1 UniProtKB/TrEMBL
Gene3D-CATH 2.60.40.10 UniProtKB/TrEMBL
InterPro Ig-like_dom UniProtKB/TrEMBL
  Ig-like_dom_sf UniProtKB/TrEMBL
  Ig-like_fold UniProtKB/TrEMBL
  Ig_sub UniProtKB/TrEMBL
  Ig_sub2 UniProtKB/TrEMBL
  Ig_V-set UniProtKB/TrEMBL
  JAM-C UniProtKB/TrEMBL
NCBI Gene Jam3 ENTREZGENE
PANTHER JUNCTIONAL ADHESION MOLECULE C UniProtKB/TrEMBL
  PTHR44598 UniProtKB/TrEMBL
Pfam Ig_3 UniProtKB/TrEMBL
  V-set UniProtKB/TrEMBL
PROSITE IG_LIKE UniProtKB/TrEMBL
SMART IGc2 UniProtKB/TrEMBL
  IGv UniProtKB/TrEMBL
  SM00409 UniProtKB/TrEMBL
Superfamily-SCOP SSF48726 UniProtKB/TrEMBL
UniProt A0A8C2W5M3 ENTREZGENE, UniProtKB/TrEMBL