Smarca5 (SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 5) - Rat Genome Database

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Gene: Smarca5 (SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 5) Chinchilla lanigera
Analyze
Symbol: Smarca5
Name: SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 5
RGD ID: 8981060
Description: ENCODES a protein that exhibits ATP binding (ortholog); ATP hydrolysis activity (ortholog); ATP-dependent chromatin remodeler activity (ortholog); INVOLVED IN antiviral innate immune response (ortholog); cellular response to leukemia inhibitory factor (ortholog); chromatin organization (ortholog); PARTICIPATES IN ISWI family mediated chromatin remodeling pathway; ASSOCIATED WITH Developmental Disabilities (ortholog); Dwarfism (ortholog); genetic disease (ortholog); FOUND IN ACF complex (ortholog); B-WICH complex (ortholog); chromatin silencing complex (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 5
RGD Orthologs
Human
Mouse
Rat
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: ChiLan1.0 - Chinchilla ChiLan1.0 Assembly
NCBI Annotation Information: Annotation category: partial on reference assembly
Position:
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495547112,203,318 - 12,237,333 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495547112,206,462 - 12,240,219 (-)NCBIChiLan1.0ChiLan1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Transitive Annotation Pipeline Automated assignment of GO, PW and RDO ISO annotations across species
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Smarca5
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495547112,203,318 - 12,237,333 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495547112,206,462 - 12,240,219 (-)NCBIChiLan1.0ChiLan1.0
SMARCA5
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh384143,513,702 - 143,557,486 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl4143,513,702 - 143,557,486 (+)EnsemblGRCh38hg38GRCh38
GRCh374144,434,855 - 144,478,639 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 364144,654,066 - 144,694,017 (+)NCBINCBI36Build 36hg18NCBI36
Build 344144,792,220 - 144,832,171NCBI
Celera4141,764,634 - 141,804,574 (+)NCBICelera
Cytogenetic Map4q31.21NCBI
HuRef4140,164,707 - 140,208,721 (+)NCBIHuRef
CHM1_14144,411,831 - 144,455,839 (+)NCBICHM1_1
T2T-CHM13v2.04146,830,915 - 146,874,681 (+)NCBIT2T-CHM13v2.0
Smarca5
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39881,426,572 - 81,466,088 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl881,425,136 - 81,466,126 (-)EnsemblGRCm39 Ensembl
GRCm38880,699,943 - 80,739,459 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl880,698,507 - 80,739,497 (-)EnsemblGRCm38mm10GRCm38
MGSCv37883,223,842 - 83,263,358 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36883,595,689 - 83,635,205 (-)NCBIMGSCv36mm8
Celera884,973,840 - 85,010,486 (-)NCBICelera
Cytogenetic Map8C2NCBI
cM Map838.41NCBI
Smarca5
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81944,172,465 - 44,208,967 (+)NCBIGRCr8
mRatBN7.21927,271,918 - 27,304,594 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1927,271,148 - 27,304,594 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1934,130,292 - 34,162,927 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01934,784,348 - 34,816,983 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01937,004,248 - 37,036,904 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01930,936,703 - 30,969,454 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1930,936,703 - 30,969,454 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01941,840,174 - 41,873,900 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41929,122,301 - 29,155,293 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11929,126,640 - 29,160,112 (+)NCBI
Celera1926,788,347 - 26,821,018 (+)NCBICelera
Cytogenetic Map19q11NCBI
SMARCA5
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v23141,384,818 - 141,431,020 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan14141,772,592 - 141,817,851 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v04135,874,888 - 135,917,096 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.14147,174,145 - 147,214,809 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl4147,174,060 - 147,214,809 (+)Ensemblpanpan1.1panPan2
SMARCA5
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11542,731,147 - 42,771,577 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1542,731,426 - 42,770,624 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1543,114,109 - 43,154,330 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01543,391,125 - 43,431,354 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1543,391,132 - 43,431,358 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11542,668,391 - 42,708,501 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01542,752,138 - 42,792,336 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01543,023,307 - 43,063,521 (+)NCBIUU_Cfam_GSD_1.0
Smarca5
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440530147,420,476 - 47,452,913 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365354,856,672 - 4,890,225 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365354,857,816 - 4,890,266 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
SMARCA5
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl884,184,576 - 84,224,871 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1884,184,572 - 84,224,943 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2889,339,602 - 89,379,481 (-)NCBISscrofa10.2Sscrofa10.2susScr3
SMARCA5
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1790,366,359 - 90,406,707 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl790,370,305 - 90,410,137 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366603769,966,455 - 70,007,230 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Smarca5
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046248483,569,744 - 3,611,104 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSCLAT00000008930   ⟹   ENSCLAP00000008802
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_00495547112,203,318 - 12,236,548 (-)Ensembl
RefSeq Acc Id: ENSCLAT00000008931   ⟹   ENSCLAP00000008803
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_00495547112,207,632 - 12,237,333 (-)Ensembl
RefSeq Acc Id: XM_013522910   ⟹   XP_013378364
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_00495547112,206,462 - 12,240,219 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_013378364 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSCLAP00000008802
  ENSCLAP00000008802.1
  ENSCLAP00000008803.1
Reference Protein Sequences
RefSeq Acc Id: XP_013378364   ⟸   XM_013522910
- UniProtKB: A0A8C2V790 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSCLAP00000008802   ⟸   ENSCLAT00000008930
RefSeq Acc Id: ENSCLAP00000008803   ⟸   ENSCLAT00000008931
Protein Domains
Helicase ATP-binding   Helicase C-terminal   SANT


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCLAG00000006153 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCLAT00000008930 ENTREZGENE
  ENSCLAT00000008930.1 UniProtKB/TrEMBL
  ENSCLAT00000008931.1 UniProtKB/TrEMBL
Gene3D-CATH 1.10.1040.30 UniProtKB/TrEMBL
  3.40.50.10810 UniProtKB/TrEMBL
  3.40.50.300 UniProtKB/TrEMBL
  Homeodomain-like UniProtKB/TrEMBL
  iswi atpase UniProtKB/TrEMBL
InterPro Helicase_ATP-bd UniProtKB/TrEMBL
  Helicase_C UniProtKB/TrEMBL
  Homeobox-like_sf UniProtKB/TrEMBL
  ISWI_HAND-dom UniProtKB/TrEMBL
  ISWI_HAND-dom_sf UniProtKB/TrEMBL
  P-loop_NTPase UniProtKB/TrEMBL
  SANT/Myb UniProtKB/TrEMBL
  SANT_dom UniProtKB/TrEMBL
  SLIDE UniProtKB/TrEMBL
  SNF2-like_sf UniProtKB/TrEMBL
  SNF2/RAD54-like_C UniProtKB/TrEMBL
  SNF2_N UniProtKB/TrEMBL
NCBI Gene LOC102018083 ENTREZGENE
PANTHER CHROMODOMAIN-HELICASE-DNA-BINDING PROTEIN 3-RELATED-RELATED UniProtKB/TrEMBL
  ISW-1 UniProtKB/TrEMBL
Pfam HAND UniProtKB/TrEMBL
  Helicase_C UniProtKB/TrEMBL
  SLIDE UniProtKB/TrEMBL
  SNF2-rel_dom UniProtKB/TrEMBL
PROSITE HELICASE_ATP_BIND_1 UniProtKB/TrEMBL
  HELICASE_CTER UniProtKB/TrEMBL
  SANT UniProtKB/TrEMBL
SMART DEXDc UniProtKB/TrEMBL
  HELICc UniProtKB/TrEMBL
  SANT UniProtKB/TrEMBL
Superfamily-SCOP SSF101224 UniProtKB/TrEMBL
  SSF46689 UniProtKB/TrEMBL
  SSF52540 UniProtKB/TrEMBL
UniProt A0A8C2V3J0_CHILA UniProtKB/TrEMBL
  A0A8C2V790 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2015-08-25 Smarca5  SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 5  LOC102018083  SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 5-like  Symbol and/or name change 5135510 APPROVED