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Gene: Slit1 (slit guidance ligand 1) Chinchilla lanigera

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Symbol:

Slit1

Name:

slit guidance ligand 1

RGD ID:

8972709

Description:

ENCODES a protein that exhibits heparan sulfate proteoglycan binding (ortholog); Roundabout binding (ortholog); INVOLVED IN axon extension involved in axon guidance (ortholog); axon guidance (ortholog); axonogenesis (ortholog); ASSOCIATED WITH Brain Injuries (ortholog); Monomelic Amyotrophy (ortholog); Spinal Cord Injuries (ortholog); FOUND IN extracellular space (ortholog)

Type:

protein-coding

RefSeq Status:

MODEL

Previously known as:

slit homolog 1

RGD Orthologs

Alliance Orthologs

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	SLIT1 (slit guidance ligand 1)	NCBI	Ortholog
Mus musculus (house mouse):	Slit1 (slit guidance ligand 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Rattus norvegicus (Norway rat):	Slit1 (slit guidance ligand 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	SLIT1 (slit guidance ligand 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	SLIT1 (slit guidance ligand 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Slit1 (slit guidance ligand 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	SLIT1 (slit guidance ligand 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	SLIT1 (slit guidance ligand 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Slit1 (slit guidance ligand 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline

Latest Assembly:

ChiLan1.0 - Chinchilla ChiLan1.0 Assembly

Position:

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955507	3,201,556 - 3,365,471 (-)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955507	3,204,135 - 3,365,319 (-)	NCBI	ChiLan1.0	ChiLan1.0

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

Brain Injuries (ISO)

Monomelic Amyotrophy (ISO)

Spinal Cord Injuries (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

axon extension involved in axon guidance (ISO)

axon guidance (ISO)

axonogenesis (ISO)

chemorepulsion involved in embryonic olfactory bulb interneuron precursor migration (ISO)

dorsal/ventral axon guidance (ISO)

motor neuron axon guidance (ISO)

negative chemotaxis (ISO)

negative regulation of axon extension involved in axon guidance (ISO)

neuron projection morphogenesis (ISO)

nuclear migration (ISO)

olfactory bulb development (ISO)

retinal ganglion cell axon guidance (ISO)

spinal cord development (ISO)

tangential migration from the subventricular zone to the olfactory bulb (ISO)

telencephalon cell migration (ISO)

Cellular Component

extracellular space (ISO)

Molecular Function

heparan sulfate proteoglycan binding (ISO)

protein binding (ISO)

Roundabout binding (ISO)

References

References - curated

#	Reference Title	Reference Citation
1.	Transitive Annotation Pipeline	Automated assignment of GO, PW and RDO ISO annotations across species

Additional References at PubMed

PMID:22301074	PMID:30032202

Genomics

Comparative Map Data

Slit1
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955507	3,201,556 - 3,365,471 (-)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955507	3,204,135 - 3,365,319 (-)	NCBI	ChiLan1.0	ChiLan1.0

SLIT1
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	10	96,998,038 - 97,185,959 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	10	96,998,038 - 97,185,959 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	10	98,757,795 - 98,945,716 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	10	98,750,601 - 98,935,653 (-)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	10	98,750,600 - 98,935,653	NCBI
Celera	10	92,499,394 - 92,687,283 (-)	NCBI		Celera
Cytogenetic Map	10	q24.1	NCBI
HuRef	10	92,385,891 - 92,573,726 (-)	NCBI		HuRef
CHM1_1	10	99,040,092 - 99,227,937 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	10	97,878,923 - 98,066,822 (-)	NCBI		T2T-CHM13v2.0

Slit1
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	19	41,586,263 - 41,735,714 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	19	41,588,696 - 41,732,104 (-)	Ensembl		GRCm39 Ensembl
GRCm38	19	41,597,824 - 41,747,275 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	19	41,600,257 - 41,743,665 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	19	41,674,747 - 41,818,346 (-)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	19	41,653,570 - 41,797,167 (-)	NCBI		MGSCv36	mm8
Celera	19	42,398,288 - 42,542,154 (-)	NCBI		Celera
Cytogenetic Map	19	C3	NCBI
cM Map	19	34.99	NCBI

Slit1
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	1	250,358,917 - 250,507,476 (-)	NCBI		GRCr8
mRatBN7.2	1	240,409,559 - 240,558,127 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	1	240,409,561 - 240,558,127 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	1	248,552,721 - 248,697,784 (-)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	1	255,249,868 - 255,394,935 (-)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	1	247,902,887 - 248,047,946 (-)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	1	260,843,481 - 260,992,366 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	1	260,843,483 - 260,992,366 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	1	268,298,678 - 268,445,090 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	1	246,813,909 - 246,964,408 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	1	246,928,385 - 247,078,883 (-)	NCBI
Celera	1	236,249,200 - 236,395,640 (-)	NCBI		Celera
Cytogenetic Map	1	q54	NCBI

SLIT1
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	8	108,910,729 - 109,098,440 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	10	108,916,049 - 109,103,762 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	10	93,618,550 - 93,806,263 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	10	97,116,073 - 97,303,406 (-)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	10	97,119,133 - 97,303,095 (-)	Ensembl	panpan1.1		panPan2

SLIT1
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	28	10,351,758 - 10,519,322 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	28	10,351,821 - 10,519,313 (-)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	28	10,535,122 - 10,702,300 (-)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	28	10,673,425 - 10,840,914 (-)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	28	10,673,458 - 10,840,953 (-)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	28	10,335,078 - 10,502,567 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	28	10,395,529 - 10,563,416 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	28	10,536,093 - 10,703,522 (-)	NCBI		UU_Cfam_GSD_1.0

Slit1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024407213	36,388,622 - 36,543,449 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936636	2,427,736 - 2,582,578 (+)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936636	2,427,738 - 2,582,565 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

SLIT1
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	14	108,446,004 - 108,624,302 (-)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	14	108,446,003 - 108,624,508 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	14	118,083,559 - 118,149,597 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

SLIT1
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	9	90,166,710 - 90,357,983 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	9	90,172,578 - 90,237,256 (-)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666048	51,061,333 - 51,250,208 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Slit1
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624737	8,460,508 - 8,632,302 (-)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624737	8,458,444 - 8,632,316 (-)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Sequence

Nucleotide Sequences


RefSeq Transcripts	XM_005407596	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AGCD01065614	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AGCD01065615	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AGCD01065616	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AGCD01065617	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AGCD01065618	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AGCD01065619	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	GBCB01111715	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSCLAT00000013406 ⟹ ENSCLAP00000013254

Type:

CODING

Position:

Chinchilla Assembly	Chr	Position (strand)	Source
ChiLan1.0 Ensembl	NW_004955507	3,201,556 - 3,365,471 (-)	Ensembl

Ensembl Acc Id:

ENSCLAT00000013407 ⟹ ENSCLAP00000013255

Type:

CODING

Position:

Chinchilla Assembly	Chr	Position (strand)	Source
ChiLan1.0 Ensembl	NW_004955507	3,201,556 - 3,365,471 (-)	Ensembl

RefSeq Acc Id:

XM_005407596 ⟹ XP_005407653

Type:

CODING

Position:

Chinchilla Assembly	Chr	Position (strand)	Source
ChiLan1.0	NW_004955507	3,204,135 - 3,365,319 (-)	NCBI

Sequence:

show sequence

GCCCATTTTCCTCGTCGCAGCAGTCAGTTGGGAGCTGGAGGGAGGGAGAGCGAGACGCAGTCGG
CGAGAAATAGGAGCGGAGCGGAGCTGAGCCGAGCGCCCTGCCCTGCTAGCGTCCGGACGTGCAT
AGGCGTCAGGAGCAGCAAGGTGCCTCCCCGCGGGCAAGGGGCAGCACGCACGCCCGCAAGGGGA
CCGCACCTGCAGGCGGCACGGACGGGGATGCCCAGCGGCTGCTGCCGTCTAGCACGCTAATGGG
ACTCGGCGAGGGCACCATGGCGGTGATGCCCGGGCGTGGGTCCTCAGCGGGGCTGGTCCGGCCG
GAGCTCTGGCTGCTGCTGTGGGCTGCTGCGTGGCGCCTGGGTGCCACGGCGTGCCCCGCCCTCT
GCACCTGCACCGGTACCACGGTGGACTGCCACGGTACGGGGCTGCAGGCCGTCCCCAAGAACAT
CCCGAGGAGCACCGAGCGCCTGGAACTCAACGGCAACAACATCACTCGGATCCATAAGAATGAC
TTTGCTGGGCTCAAGCAGCTTCGGGTGCTGCAGCTGATGGAGAACCAGATCGGAGCTGTGGAGC
GAGGGGCTTTTGATGACATGAAGGAGCTGGAGCGGCTACGACTGAACCGGAACCAGCTACATAC
GTTGCCAGAACTGCTATTCCAGAACAACCAGGCTCTGTCCAGACTGGACCTGAGCGAGAACGCC
CTGCAGGCCATCCCCAGGAAGGCTTTCCGCGGAGCCACAGATCTCAAAAACCTACAGCTGGACA
AGAACCAGATCAGCTGCATTGAGGAAGGGGCCTTCCGGGCCTTGCGGGGTCTGGAGGTGCTGAC
CCTGAACAACAACAACATCACCACGATTCCGGTGTCCAGCTTCAACCACATGCCCAAGCTGCGG
ACCTTCCGCCTGCACTCCAACCACCTGTTCTGTGACTGCCACCTGGCCTGGCTGTCGCAGTGGC
TGAGGCAGCGGCCGACCATCGGACTCTTTACCCAGTGCTCGGGCCCCGCCAGCCTGCGTGGCCT
CAATGTGGCTGAGGTCCAGAAGAGCGAGTTCAGCTGCTCAGGCCAGGGGGAGGCGGGACGAGTG
CCTGCCTGCACCCTTTCTTCCGGTTCCTGCCCAGCCATGTGCACCTGCAGCAACGGTATTGTGG
ACTGTCGCGGCAAAGGCCTCACCGCCATCCCTGCCAACCTGCCCGAGACCATGACAGAGATCCG
GTTGGAGCTCAATGGAATCAAGTCCATCCCTCCAGGAGCCTTCTCTCCCTACAGAAAGCTGCGC
AGGATAGACCTGAGCAACAATCAGATTGCTGAGATCGCACCTGACGCCTTCCAGGGCCTCCGCT
CCTTGAACTCACTGGTCCTCTATGGGAACAAGATCACAGACCTCCCCCGCGGTGTGTTTGGAGG
CCTGTACACACTACAGCTTCTGCTCCTGAATGCCAACAAGATCAACTGCATCCGGCCTGATGCC
TTCCAGGACCTACAGAACCTCTCACTACTCTCCCTGTATGACAACAAGATCCAGAGTCTTGCCA
AGGGCACCTTCACATCCCTGAGGGCCATCCAGACACTGCATCTGGCCCAGAACCCTTTTATCTG
CGACTGTAACCTCAAGTGGCTGGCGGACTTTCTACGCACTAATCCCATAGAGACAAGTGGGGCC
CGCTGTGCCAGTCCCCGGCGCCTCGCCAACAAGCGCATCGGGCAGATCAAGAGCAAGAAGTTCC
GGTGCTCAGCCAAAGAGCAGTACTTCATTCCAGGCACCGAGGACTACCAGCTGAACAGCGAGTG
CAGCAGCGATGTTGCCTGTCCCCACAAGTGCCGCTGTGAGGCCAGTATGGTGGAGTGCTCCAGC
CTGAAGCTCTCCAAGATCCCTGAGCGCATCCCGCAGTCCACAGCCGAGCTACGATTGAACAACA
ATGAAATTTCCCTCCTTGAGGCCACTGGGATGTTTAAAAAACTTACACATCTGAAGAAAATCAA
CCTGAGCAACAACAAGGTATCAGAAATTGAAGACGGCACATTCGAGGGCGCGGCCTCCGTGAGT
GAGCTGCACCTGACTGCCAACCAGCTGGAGTCTATCCGGAGTGGCATGTTCCGGGGTCTGGACG
GTTTGCGGACCCTGATGCTAAGGAACAACCGTATCAGCTGCATCCACAACGACAGCTTCACGGG
CCTGCGCAACGTCCGGCTGCTCTCGCTGTACGACAATCACATCACCACCATCTCCCCTGGAGCC
TTCGATACCCTGCAGGCTCTCTCCACGCTAAACCTCCTGGCCAACCCGTTCAACTGTAACTGCC
AGCTGGCCTGGCTGGGCGACTGGCTGAGGAAGAGGAAGATTGTGACGGGGAACCCTCGATGCCA
GAACCCAGACTTTTTGCGGCAGATCCCTCTGCAGGATGTGGCCTTCCCTGACTTCAGGTGTGAG
GAAGGCCAGGAGGAGGGGGGCTGCCTGCCGCGACCGCAGTGCCCCCAGGAGTGTGCCTGCCTGG
ACACCGTGGTCCGATGCAGCAACAAGCACCTGCAGGCTCTGCCCAAGGGCATCCCCAAGAATGT
CACAGAGCTCTACTTGGATGGCAACCAGTTCACACTGGTTCCAGGTCAACTGTCTACCTTCAAA
TACTTGCAACTTGTGGACCTCAGTAACAACAAGATCAGTTCCTTAAGCAATTCCTCCTTCACCA
ACATGAGCCAGCTGACCACTCTGATCCTCAGCTACAACGCCCTCCAGTGCATCCCTCCTCTGGC
CTTCCAGGGGCTCCATTCGCTGCGCCTGCTGTCCCTCCATGGCAATGACGTCTCCACCCTCCAA
GAGGGCGTCTTCGCAGATGTGACCTCACTGTCTCACCTGGCTATCGGTGCCAATCCTCTGTACT
GTGACTGCCACCTCCGCTGGCTATCCAACTGGGTGAAAACTGGCTACAAGGAACCGGGCATTGC
CCGCTGCGCTGGGCCCCCAGACATGGAGGGCAAGCTGTTGCTCACCACGCCTGCCAAGAAGTTT
GAATGCCAAGGTCCCCCCACTCTGGCTGTCCAGACCAAGTGTGAGCCCTGCTTGTCCAGCCCAT
GCCAGAATCAGGGCACCTGCCACAATGACCCCTTTGAGATGTACAGGTGTGTCTGCCCCAGTGG
CTATAAGGGCCGACACTGTGAGGTATCCTCAGACAGCTGTTCCAGCAACCCTTGTGGAAATGGG
GGGACCTGTCAAGCTGAGGAAGGCAAGGATGCCAGCTTCACGTGCTCCTGTCCCATTGGCTTTG
AAGGACCAACCTGTGGAGTGAACGTGGACGACTGCGTGGAGCATGCCTGTGCCAATGGGGGCAT
CTGTGTCGACGGTGTGAGCAACTACACCTGCCAGTGCCCCCCACAGTTTGTGGGAAGGGCCTGC
GAGCAGCCGGTGGACTTTTGCTCTCCAGGTCTGAACCCGTGTCAGCATGAGGCCCAGTGCGTGG
GCACCCCAGATGGGCCCAGGTGTGAATGTGCACCAGGTTATACAGGTGACAACTGCAGTGAAAA
CCAAGATGACTGCAGGGGTCACCGCTGCCAGAATGGGGCCCAGTGTGTGGACGCAGTCAACAGC
TACACTTGCCTCTGTGCCAAGGGTTACAGTGGACAGCTCTGTGAGATCCCTCCCTACCCACCCG
CTCCCAGGAACCCCTGCGAGGGGACTGAGTGCCAGAATGGGGCCAACTGCGTGGACCAGGGCAG
CCAGCCTGTGTGCCAGTGCCTCCCAGGCTTCAGTGGTCCTGAGTGTGAGAAGTTGCTCAGTGTC
AACTTTGTGGATCGGGACACTTACCTGCAGTTCACTGACCTGCAGAATTGGCCACGGGCCAACA
TCACACTACAGGTCTCTACAGCAGAGGACAACGGGATTCTGCTATACAACGGGGACAATGACCA
TATCGCAGTTGAGTTGTACCAGGGCCATGTGCGTGTCAGCTATGACCCAGGCAGCTACCCCAGT
TCTGCCATCTACAGTGCTGAGATGATCAATGATGGGCAGTTCCACACTGTTGAACTGGTCACCT
TTGACCAGATGGTGAACCTCTCCATCGATGGCGGCAGTCCCATGACCATGGACAACTTCGGCAA
ACACTATACACTCAACAGTGAGGCGCCCCTCTATGTGGGAGGGATGCCAGTGGATGTGAACTCA
GCTGCCTTCCGCCTGTGGCAGATCCTTAACGGTACCAGCTTCCATGGTTGCATCCGAAACCTGT
ACATAAACAATGAGCTGCAGGACTTCACTAAGACGCAGATGAAACCAGGCGTGGTGCCAGGCTG
TGAACCCTGTCGCAAACTCTACTGCCTGCACGGCATCTGCCAGCCCAATGCCACCCCAGGCCCC
GTGTGCCACTGTGAGGCTGGCTGGGGGGGCCTTCACTGTGACCAGCCCGCTGATGGCCCCTGCC
ATGGCCACAAGTGTGTCCATGGGAAATGTGTGCCCCTCGATGCCCTTTCCTACAGCTGCCAGTG
CCAGGAGGGGTACTCAGGGGCCCTATGCAACCAGGCGGGGGCAGTGGTAGAGCCCTGTGGGGGC
CTGCAATGCCTGCATGGCCACTGCCAGGCTTCGGCCACCAAGGGGGTACACTGTGTGTGTGACC
CTGGCTTTTCAGGAGAGCTGTGTGAGCAAGAGTCCGAGTGCCGGGGGGACCCTGTCCGGGATTT
TCACCGGGTCCAGAGGGGCTATGCCATCTGCCAAACCACGCGCCCGCTATCATGGGTGGAGTGC
CGGGGCATGTGCCCAGGCCAGGGCTGCTGCCAGGGCCTGCGGCTGAAGCGGAGGAAGCTCACCT
TCGAGTGCAGCGATGGGACCTCTTTTGCCAAGGAGGTGGAGAAGCCTACCAAATGTGGTTGTTC
CCTCTGCATTTAGGTGGCGTGCACCAAGCAGCCACAGGCAGGGCAACAGAGTCGGCAGCTGGTT
GGGGTGTGGGCATCACCTGGGCAGTGCTTGGGCCTTGGTGGGCATGGGGCCTAATAGCATCAAA
GCCCGGCAGAAGGCAGGTTGGAGCTATGGCCGCCCTCTCTGGAAGTGCCTTGCACAAACAGGCG
CTCAATAAATATTTGTTGAATGAA

hide sequence

Protein Sequences


Protein RefSeqs	XP_005407653	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSCLAP00000013254.1
	ENSCLAP00000013255
	ENSCLAP00000013255.1

RefSeq Acc Id:

XP_005407653 ⟸ XM_005407596

- UniProtKB:

A0A8C2VIA4 (UniProtKB/TrEMBL), A0A8C2VFI7 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MGLGEGTMAVMPGRGSSAGLVRPELWLLLWAAAWRLGATACPALCTCTGTTVDCHGTGLQAVPK
NIPRSTERLELNGNNITRIHKNDFAGLKQLRVLQLMENQIGAVERGAFDDMKELERLRLNRNQL
HTLPELLFQNNQALSRLDLSENALQAIPRKAFRGATDLKNLQLDKNQISCIEEGAFRALRGLEV
LTLNNNNITTIPVSSFNHMPKLRTFRLHSNHLFCDCHLAWLSQWLRQRPTIGLFTQCSGPASLR
GLNVAEVQKSEFSCSGQGEAGRVPACTLSSGSCPAMCTCSNGIVDCRGKGLTAIPANLPETMTE
IRLELNGIKSIPPGAFSPYRKLRRIDLSNNQIAEIAPDAFQGLRSLNSLVLYGNKITDLPRGVF
GGLYTLQLLLLNANKINCIRPDAFQDLQNLSLLSLYDNKIQSLAKGTFTSLRAIQTLHLAQNPF
ICDCNLKWLADFLRTNPIETSGARCASPRRLANKRIGQIKSKKFRCSAKEQYFIPGTEDYQLNS
ECSSDVACPHKCRCEASMVECSSLKLSKIPERIPQSTAELRLNNNEISLLEATGMFKKLTHLKK
INLSNNKVSEIEDGTFEGAASVSELHLTANQLESIRSGMFRGLDGLRTLMLRNNRISCIHNDSF
TGLRNVRLLSLYDNHITTISPGAFDTLQALSTLNLLANPFNCNCQLAWLGDWLRKRKIVTGNPR
CQNPDFLRQIPLQDVAFPDFRCEEGQEEGGCLPRPQCPQECACLDTVVRCSNKHLQALPKGIPK
NVTELYLDGNQFTLVPGQLSTFKYLQLVDLSNNKISSLSNSSFTNMSQLTTLILSYNALQCIPP
LAFQGLHSLRLLSLHGNDVSTLQEGVFADVTSLSHLAIGANPLYCDCHLRWLSNWVKTGYKEPG
IARCAGPPDMEGKLLLTTPAKKFECQGPPTLAVQTKCEPCLSSPCQNQGTCHNDPFEMYRCVCP
SGYKGRHCEVSSDSCSSNPCGNGGTCQAEEGKDASFTCSCPIGFEGPTCGVNVDDCVEHACANG
GICVDGVSNYTCQCPPQFVGRACEQPVDFCSPGLNPCQHEAQCVGTPDGPRCECAPGYTGDNCS
ENQDDCRGHRCQNGAQCVDAVNSYTCLCAKGYSGQLCEIPPYPPAPRNPCEGTECQNGANCVDQ
GSQPVCQCLPGFSGPECEKLLSVNFVDRDTYLQFTDLQNWPRANITLQVSTAEDNGILLYNGDN
DHIAVELYQGHVRVSYDPGSYPSSAIYSAEMINDGQFHTVELVTFDQMVNLSIDGGSPMTMDNF
GKHYTLNSEAPLYVGGMPVDVNSAAFRLWQILNGTSFHGCIRNLYINNELQDFTKTQMKPGVVP
GCEPCRKLYCLHGICQPNATPGPVCHCEAGWGGLHCDQPADGPCHGHKCVHGKCVPLDALSYSC
QCQEGYSGALCNQAGAVVEPCGGLQCLHGHCQASATKGVHCVCDPGFSGELCEQESECRGDPVR
DFHRVQRGYAICQTTRPLSWVECRGMCPGQGCCQGLRLKRRKLTFECSDGTSFAKEVEKPTKCG
CSLCI

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Ensembl Acc Id:

ENSCLAP00000013254 ⟸ ENSCLAT00000013406

Ensembl Acc Id:

ENSCLAP00000013255 ⟸ ENSCLAT00000013407

Protein Domains

CTCK EGF-like Laminin G

Additional Information

External Database Links

Database	Acc Id	Source(s)
Ensembl Genes	ENSCLAG00000009153	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSCLAT00000013406.1	UniProtKB/TrEMBL
	ENSCLAT00000013407	ENTREZGENE
	ENSCLAT00000013407.1	UniProtKB/TrEMBL
Gene3D-CATH	2.60.120.200	UniProtKB/TrEMBL
	3.80.10.10	UniProtKB/TrEMBL
	Laminin	UniProtKB/TrEMBL
InterPro	ConA-like_dom_sf	UniProtKB/TrEMBL
	Cys-rich_flank_reg_C	UniProtKB/TrEMBL
	Cys_knot_C	UniProtKB/TrEMBL
	EGF-like_Ca-bd_dom	UniProtKB/TrEMBL
	EGF-like_CS	UniProtKB/TrEMBL
	EGF-like_dom	UniProtKB/TrEMBL
	EGF-type_Asp/Asn_hydroxyl_site	UniProtKB/TrEMBL
	EGF_Ca-bd_CS	UniProtKB/TrEMBL
	Growth_fac_rcpt_cys_sf	UniProtKB/TrEMBL
	Laminin_G	UniProtKB/TrEMBL
	Leu-rich_rpt	UniProtKB/TrEMBL
	Leu-rich_rpt_typical-subtyp	UniProtKB/TrEMBL
	LRR_dom_sf	UniProtKB/TrEMBL
	LRRNT	UniProtKB/TrEMBL
	Notch/Slit_guidance	UniProtKB/TrEMBL
NCBI Gene	Slit1	ENTREZGENE
PANTHER	SLIT HOMOLOG	UniProtKB/TrEMBL
	SLIT HOMOLOG 1 PROTEIN	UniProtKB/TrEMBL
Pfam	EGF	UniProtKB/TrEMBL
	hEGF	UniProtKB/TrEMBL
	Laminin_G_2	UniProtKB/TrEMBL
	LRR_8	UniProtKB/TrEMBL
	LRRCT	UniProtKB/TrEMBL
	LRRNT	UniProtKB/TrEMBL
PROSITE	ASX_HYDROXYL	UniProtKB/TrEMBL
	CTCK_1	UniProtKB/TrEMBL
	CTCK_2	UniProtKB/TrEMBL
	EGF_1	UniProtKB/TrEMBL
	EGF_2	UniProtKB/TrEMBL
	EGF_3	UniProtKB/TrEMBL
	EGF_CA	UniProtKB/TrEMBL
	LAM_G_DOMAIN	UniProtKB/TrEMBL
	LRR	UniProtKB/TrEMBL
SMART	EGF	UniProtKB/TrEMBL
	EGF_CA	UniProtKB/TrEMBL
	LamG	UniProtKB/TrEMBL
	LRR_SD22	UniProtKB/TrEMBL
	LRR_TYP	UniProtKB/TrEMBL
	LRRCT	UniProtKB/TrEMBL
	LRRNT	UniProtKB/TrEMBL
	SM00041	UniProtKB/TrEMBL
Superfamily-SCOP	EGF/Laminin	UniProtKB/TrEMBL
	L domain-like	UniProtKB/TrEMBL
	SSF49899	UniProtKB/TrEMBL
	SSF57184	UniProtKB/TrEMBL
UniProt	A0A8C2VFI7	ENTREZGENE, UniProtKB/TrEMBL
	A0A8C2VIA4	ENTREZGENE, UniProtKB/TrEMBL

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2015-08-25	Slit1	slit guidance ligand 1		slit homolog 1 (Drosophila)	Symbol and/or name change	5135510	APPROVED

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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Imported Disease Annotations - ClinVar