Plekha3 (pleckstrin homology domain containing A3) - Rat Genome Database

Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Gene: Plekha3 (pleckstrin homology domain containing A3) Chinchilla lanigera
Analyze
Symbol: Plekha3
Name: pleckstrin homology domain containing A3
RGD ID: 8972043
Description: ENCODES a protein that exhibits identical protein binding (ortholog); phosphatidylinositol-4-phosphate binding (ortholog); ASSOCIATED WITH dilated cardiomyopathy 1G (ortholog); dystonia 16 (ortholog); genetic disease (ortholog); FOUND IN Golgi apparatus (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 3; pleckstrin homology domain-containing family A member 3
RGD Orthologs
Human
Mouse
Rat
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: ChiLan1.0 - Chinchilla ChiLan1.0 Assembly
NCBI Annotation Information: Annotation category: partial on reference assembly
Position:
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540318,343,983 - 18,366,516 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495540318,347,309 - 18,366,503 (-)NCBIChiLan1.0ChiLan1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Transitive Annotation Pipeline Automated assignment of GO, PW and RDO ISO annotations across species
Additional References at PubMed
PMID:30032202  


Genomics

Comparative Map Data
Plekha3
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540318,343,983 - 18,366,516 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495540318,347,309 - 18,366,503 (-)NCBIChiLan1.0ChiLan1.0
PLEKHA3
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382178,480,457 - 178,516,463 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2178,480,457 - 178,516,463 (+)EnsemblGRCh38hg38GRCh38
GRCh372179,345,184 - 179,381,190 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 362179,053,445 - 179,078,029 (+)NCBINCBI36Build 36hg18NCBI36
Build 342179,170,705 - 179,195,287NCBI
Celera2172,948,086 - 172,972,669 (+)NCBICelera
Cytogenetic Map2q31.2NCBI
HuRef2171,215,642 - 171,240,227 (+)NCBIHuRef
CHM1_12179,351,223 - 179,375,833 (+)NCBICHM1_1
T2T-CHM13v2.02178,963,251 - 178,999,257 (+)NCBIT2T-CHM13v2.0
Plekha3
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39276,505,436 - 76,527,679 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl276,505,625 - 76,527,172 (+)EnsemblGRCm39 Ensembl
GRCm38276,675,305 - 76,697,335 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl276,675,281 - 76,696,828 (+)EnsemblGRCm38mm10GRCm38
MGSCv37276,513,372 - 76,535,392 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36276,476,134 - 76,497,412 (+)NCBIMGSCv36mm8
Celera278,336,988 - 78,359,010 (+)NCBICelera
Cytogenetic Map2C3NCBI
cM Map245.1NCBI
Plekha3
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8382,030,653 - 82,051,866 (+)NCBIGRCr8
mRatBN7.2361,623,434 - 61,644,649 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl361,623,434 - 61,645,166 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx364,978,740 - 64,999,886 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0373,562,393 - 73,583,539 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0371,330,012 - 71,351,172 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0363,536,166 - 63,557,378 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl363,536,166 - 63,557,361 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0370,108,027 - 70,131,802 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4359,375,462 - 59,396,674 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1359,271,833 - 59,293,029 (+)NCBI
Celera361,109,037 - 61,130,098 (+)NCBICelera
Cytogenetic Map3q24NCBI
PLEKHA3
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21381,128,623 - 81,187,421 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12B81,142,982 - 81,179,132 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02B65,738,043 - 65,774,021 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12B183,442,402 - 183,466,628 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2B183,442,408 - 183,466,628 (+)Ensemblpanpan1.1panPan2
PLEKHA3
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13622,101,111 - 22,130,273 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl3622,101,677 - 22,129,123 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha3622,119,675 - 22,149,366 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.03622,244,986 - 22,274,670 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl3622,247,913 - 22,273,936 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.13622,354,359 - 22,383,971 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.03622,317,178 - 22,346,866 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.03622,433,451 - 22,463,170 (+)NCBIUU_Cfam_GSD_1.0
Plekha3
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405303139,139,384 - 139,163,356 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365097,693,287 - 7,718,088 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365097,693,287 - 7,717,259 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
PLEKHA3
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1584,184,998 - 84,212,119 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11584,185,007 - 84,206,887 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21593,718,706 - 93,740,122 (+)NCBISscrofa10.2Sscrofa10.2susScr3
PLEKHA3
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11064,030,470 - 64,055,568 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1064,030,686 - 64,054,358 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666040135,519,175 - 135,544,254 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Plekha3
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_004624844446,961 - 469,055 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_004624844446,946 - 469,425 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence


RefSeq Acc Id: ENSCLAT00000020832   ⟹   ENSCLAP00000020634
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_00495540318,343,983 - 18,366,516 (-)Ensembl
RefSeq Acc Id: XM_013512613   ⟹   XP_013368067
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_00495540318,347,309 - 18,366,503 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_013368067 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSCLAP00000020634
  ENSCLAP00000020634.1
RefSeq Acc Id: XP_013368067   ⟸   XM_013512613
- UniProtKB: A0A8C2YSS2 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSCLAP00000020634   ⟸   ENSCLAT00000020832
Protein Domains
PH


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCLAG00000014135 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCLAT00000020832 ENTREZGENE
  ENSCLAT00000020832.1 UniProtKB/TrEMBL
Gene3D-CATH 2.30.29.30 UniProtKB/TrEMBL
InterPro Boi1/Boi2-like UniProtKB/TrEMBL
  PH-like_dom_sf UniProtKB/TrEMBL
  PH_domain UniProtKB/TrEMBL
NCBI Gene Plekha3 ENTREZGENE
PANTHER PLECKSTRIN HOMOLOGY DOMAIN-CONTAINING FAMILY A MEMBER 3 UniProtKB/TrEMBL
  SESQUIPEDALIAN UniProtKB/TrEMBL
Pfam PF00169 UniProtKB/TrEMBL
PROSITE PH_DOMAIN UniProtKB/TrEMBL
SMART SM00233 UniProtKB/TrEMBL
Superfamily-SCOP PH domain-like UniProtKB/TrEMBL
UniProt A0A8C2YSS2 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-08-16 Plekha3  pleckstrin homology domain containing A3    pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 3  Symbol and/or name change 5135510 APPROVED