Thtpa (thiamine triphosphatase) - Rat Genome Database

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Gene: Thtpa (thiamine triphosphatase) Chinchilla lanigera
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Symbol: Thtpa
Name: thiamine triphosphatase
RGD ID: 8970289
Description: ENCODES a protein that exhibits magnesium ion binding (ortholog); thiamine triphosphate phosphatase activity (ortholog); INVOLVED IN thiamine diphosphate biosynthetic process (ortholog); thiamine diphosphate metabolic process (ortholog); PARTICIPATES IN thiamine metabolic pathway; ASSOCIATED WITH Brain-Lung-Thyroid Syndrome (ortholog); genetic disease (ortholog); lysinuric protein intolerance (ortholog); FOUND IN cytosol (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: thiamine-triphosphatase
RGD Orthologs
Human
Mouse
Rat
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: ChiLan1.0 - Chinchilla ChiLan1.0 Assembly
Position:
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540936,804,258 - 36,808,091 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495540936,803,721 - 36,808,094 (-)NCBIChiLan1.0ChiLan1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
cytosol  (ISO)

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Transitive Annotation Pipeline Automated assignment of GO, PW and RDO ISO annotations across species
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Thtpa
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540936,804,258 - 36,808,091 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495540936,803,721 - 36,808,094 (-)NCBIChiLan1.0ChiLan1.0
THTPA
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381423,511,760 - 23,560,271 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1423,555,988 - 23,560,271 (+)EnsemblGRCh38hg38GRCh38
GRCh371423,980,969 - 24,029,480 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361423,095,071 - 23,098,592 (+)NCBINCBI36Build 36hg18NCBI36
Build 341423,095,070 - 23,098,592NCBI
Celera143,887,868 - 3,891,457 (+)NCBICelera
Cytogenetic Map14q11.2NCBI
HuRef144,097,332 - 4,145,309 (+)NCBIHuRef
CHM1_11423,979,628 - 24,027,450 (+)NCBICHM1_1
T2T-CHM13v2.01417,712,320 - 17,760,830 (+)NCBIT2T-CHM13v2.0
Thtpa
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391455,332,241 - 55,336,452 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1455,332,241 - 55,336,443 (+)EnsemblGRCm39 Ensembl
GRCm381455,094,784 - 55,098,995 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1455,094,784 - 55,098,986 (+)EnsemblGRCm38mm10GRCm38
MGSCv371455,713,621 - 55,717,832 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361454,048,906 - 54,053,053 (+)NCBIMGSCv36mm8
Celera1452,900,681 - 52,904,892 (+)NCBICelera
Cytogenetic Map14C3NCBI
cM Map1428.07NCBI
Thtpa
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81532,536,297 - 32,541,537 (+)NCBIGRCr8
mRatBN7.21528,567,619 - 28,571,580 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1528,567,323 - 28,571,580 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1530,413,650 - 30,417,289 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01531,560,842 - 31,564,481 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01529,803,502 - 29,807,141 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01533,755,157 - 33,759,117 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1533,755,478 - 33,759,115 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01537,640,608 - 37,646,202 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41533,201,426 - 33,205,065 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11533,217,763 - 33,219,293 (+)NCBI
Celera1528,145,924 - 28,149,563 (+)NCBICelera
Cytogenetic Map15p13NCBI
THTPA
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21524,986,749 - 24,990,593 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11424,203,241 - 24,207,085 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0144,374,439 - 4,378,028 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11422,467,506 - 22,471,356 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1422,467,506 - 22,471,356 (+)Ensemblpanpan1.1panPan2
THTPA
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.183,781,931 - 3,785,093 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl83,782,163 - 3,785,394 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha83,703,805 - 3,708,801 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.083,892,212 - 3,897,208 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl83,892,317 - 3,898,687 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.183,584,212 - 3,588,417 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.083,644,873 - 3,649,869 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.083,906,958 - 3,911,954 (+)NCBIUU_Cfam_GSD_1.0
Thtpa
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440864035,485,267 - 35,532,974 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936722855,975 - 863,098 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936722858,119 - 904,630 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
THTPA
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl775,545,973 - 75,552,904 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1775,548,430 - 75,553,721 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2780,862,681 - 80,867,802 (-)NCBISscrofa10.2Sscrofa10.2susScr3
THTPA
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12923,883,363 - 23,930,710 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2923,926,813 - 23,929,981 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605922,487,907 - 22,534,963 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Thtpa
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248209,020,179 - 9,022,057 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248209,010,936 - 9,022,935 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence


RefSeq Acc Id: ENSCLAT00000023163   ⟹   ENSCLAP00000022947
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_00495540936,804,258 - 36,808,091 (-)Ensembl
RefSeq Acc Id: XM_005377061   ⟹   XP_005377118
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_00495540936,804,258 - 36,808,091 (-)NCBI
Sequence:
RefSeq Acc Id: XM_013510425   ⟹   XP_013365879
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_00495540936,803,721 - 36,808,094 (-)NCBI
Sequence:
RefSeq Acc Id: XM_013510426   ⟹   XP_013365880
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_00495540936,803,721 - 36,808,088 (-)NCBI
Sequence:
RefSeq Acc Id: XM_013510427   ⟹   XP_013365881
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_00495540936,803,721 - 36,808,093 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_005377118 (Get FASTA)   NCBI Sequence Viewer  
  XP_013365879 (Get FASTA)   NCBI Sequence Viewer  
  XP_013365880 (Get FASTA)   NCBI Sequence Viewer  
  XP_013365881 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSCLAP00000022947
  ENSCLAP00000022947.1
RefSeq Acc Id: XP_005377118   ⟸   XM_005377061
- Peptide Label: isoform X2
- UniProtKB: A0A8C2VZH6 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_013365879   ⟸   XM_013510425
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_013365881   ⟸   XM_013510427
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_013365880   ⟸   XM_013510426
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: ENSCLAP00000022947   ⟸   ENSCLAT00000023163
Protein Domains
CYTH


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCLAG00000015748 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCLAT00000023163 ENTREZGENE
  ENSCLAT00000023163.1 UniProtKB/TrEMBL
Gene3D-CATH Hypothetical Protein Pfu-838710-001 UniProtKB/TrEMBL
InterPro CYTH-like_dom_sf UniProtKB/TrEMBL
  CYTH_domain UniProtKB/TrEMBL
  THTPA UniProtKB/TrEMBL
  ThTPase_euk UniProtKB/TrEMBL
NCBI Gene Thtpa ENTREZGENE
PANTHER PTHR14586 UniProtKB/TrEMBL
  THIAMINE-TRIPHOSPHATASE UniProtKB/TrEMBL
Pfam CYTH UniProtKB/TrEMBL
PIRSF ThTPase UniProtKB/TrEMBL
PROSITE CYTH UniProtKB/TrEMBL
SMART CYTH UniProtKB/TrEMBL
Superfamily-SCOP SSF55154 UniProtKB/TrEMBL
UniProt A0A8C2VZH6 ENTREZGENE, UniProtKB/TrEMBL