Irf8 (interferon regulatory factor 8)

Gene: Irf8 (interferon regulatory factor 8) Chinchilla lanigera

Analyze

Symbol:

Irf8

Name:

interferon regulatory factor 8

RGD ID:

8969679

Description:

ENCODES a protein that exhibits DNA binding (ortholog); DNA-binding transcription repressor activity, RNA polymerase II-specific (ortholog); RNA polymerase II cis-regulatory region sequence-specific DNA binding (ortholog); INVOLVED IN cellular response to lipopolysaccharide (ortholog); cellular response to type II interferon (ortholog); defense response to bacterium (ortholog); PARTICIPATES IN granulocyte-macrophage colony-stimulating factor signaling pathway; ASSOCIATED WITH B-lymphoblastic leukemia/lymphoma (ortholog); Behcet's disease (ortholog); cardiomyopathy (ortholog); FOUND IN cytoplasm (ortholog); nucleoplasm (ortholog); nucleus (ortholog)

Type:

protein-coding

RefSeq Status:

RGD Orthologs

Alliance Genes

More Info

more info ...

Latest Assembly:

ChiLan1.0 - Chinchilla ChiLan1.0 Assembly

Position:

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955541	973,022 - 990,106 (+)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955541	973,004 - 988,493 (+)	NCBI	ChiLan1.0	ChiLan1.0

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

B-lymphoblastic leukemia/lymphoma (ISO)

Behcet's disease (ISO)

cardiomyopathy (ISO)

cerebral infarction (ISO)

Coronary Disease (ISO)

Experimental Liver Cirrhosis (ISO)

familial chronic myelocytic leukemia-like syndrome (ISO)

genetic disease (ISO)

immunodeficiency 32A (ISO)

immunodeficiency 32B (ISO)

Liver Reperfusion Injury (ISO)

multiple myeloma (ISO)

multiple sclerosis (ISO)

myeloid neoplasm (ISO)

Neointima (ISO)

persistent fetal circulation syndrome (ISO)

primary immunodeficiency disease (ISO)

rheumatoid arthritis (ISO)

systemic lupus erythematosus (ISO)

Tracheoesophageal Fistula (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

cellular response to lipopolysaccharide (ISO)

cellular response to type II interferon (ISO)

defense response to bacterium (ISO)

defense response to protozoan (ISO)

dendritic cell differentiation (ISO)

follicular B cell differentiation (ISO)

germinal center B cell differentiation (ISO)

immune response (ISO)

myeloid cell differentiation (ISO)

negative regulation of transcription by RNA polymerase II (ISO)

phagocytosis (ISO)

plasmacytoid dendritic cell differentiation (ISO)

positive regulation of apoptotic process (ISO)

positive regulation of DNA-templated transcription (ISO)

positive regulation of interleukin-12 production (ISO)

positive regulation of transcription by RNA polymerase II (ISO)

positive regulation of type II interferon production (ISO)

regulation of type I interferon production (ISO)

response to bacterium (ISO)

Cellular Component

cytoplasm (ISO)

nucleoplasm (ISO)

nucleus (ISO)

Molecular Function

DNA binding (ISO)

DNA-binding transcription repressor activity, RNA polymerase II-specific (ISO)

protein binding (ISO)

RNA polymerase II cis-regulatory region sequence-specific DNA binding (ISO)

RNA polymerase II transcription regulatory region sequence-specific DNA binding (ISO)

sequence-specific double-stranded DNA binding (ISO)

Molecular Pathway Annotations Click to see Annotation Detail View

granulocyte-macrophage colony-stimulating factor signaling pathway (ISO)

References

References - curated

#	Reference Title	Reference Citation
1.	Transitive Annotation Pipeline	Automated assignment of GO, PW and RDO ISO annotations across species
2.	OMIM Disease Annotation Pipeline	OMIM Disease Annotation Pipeline

Additional References at PubMed

PMID:22301074	PMID:30032202

Genomics

Comparative Map Data

Irf8
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955541	973,022 - 990,106 (+)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955541	973,004 - 988,493 (+)	NCBI	ChiLan1.0	ChiLan1.0

IRF8
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	16	85,899,162 - 85,922,609 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	16	85,899,116 - 85,922,606 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	16	85,932,768 - 85,956,215 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	16	84,490,275 - 84,513,713 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	16	84,490,274 - 84,513,710	NCBI
Celera	16	70,235,758 - 70,259,207 (+)	NCBI		Celera
Cytogenetic Map	16	q24.1	NCBI
HuRef	16	71,673,680 - 71,697,160 (+)	NCBI		HuRef
CHM1_1	16	87,344,316 - 87,367,790 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	16	91,965,661 - 91,989,108 (+)	NCBI		T2T-CHM13v2.0

Irf8
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	8	121,463,097 - 121,483,433 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	8	121,463,097 - 121,483,433 (+)	Ensembl		GRCm39 Ensembl
GRCm38	8	120,736,358 - 120,756,694 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	8	120,736,358 - 120,756,694 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	8	123,260,276 - 123,280,594 (+)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	8	123,622,353 - 123,642,671 (+)	NCBI		MGSCv36	mm8
Celera	8	124,952,030 - 124,972,392 (+)	NCBI		Celera
Cytogenetic Map	8	E1	NCBI
cM Map	8	70.05	NCBI

Irf8
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	19	65,699,284 - 65,721,066 (+)	NCBI		GRCr8
mRatBN7.2	19	48,790,581 - 48,812,363 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	19	48,790,588 - 48,811,829 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	19	55,588,302 - 55,604,928 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	19	56,269,197 - 56,285,845 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	19	58,487,122 - 58,503,763 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	19	54,314,859 - 54,336,643 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	19	54,314,865 - 54,336,640 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	19	65,033,704 - 65,055,534 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	19	51,100,088 - 51,116,730 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	19	51,104,968 - 51,121,611 (+)	NCBI
Celera	19	48,045,909 - 48,062,560 (+)	NCBI		Celera
Cytogenetic Map	19	q12	NCBI

IRF8
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	18	95,651,335 - 95,675,613 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	16	101,568,444 - 101,593,081 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	16	66,568,370 - 66,591,949 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	16	85,905,334 - 85,929,073 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	16	85,905,334 - 85,929,073 (+)	Ensembl	panpan1.1		panPan2

IRF8
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	5	66,789,264 - 66,812,477 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	5	66,791,350 - 66,842,179 (-)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	5	66,805,485 - 66,828,693 (-)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	5	67,017,551 - 67,040,770 (-)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	5	67,018,777 - 67,056,060 (-)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	5	67,037,979 - 67,061,164 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	5	66,873,445 - 66,896,641 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	5	67,286,849 - 67,310,056 (-)	NCBI		UU_Cfam_GSD_1.0

Irf8
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024409349	26,854,556 - 26,869,478 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936641	2,608,100 - 2,622,409 (-)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936641	2,608,109 - 2,622,446 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

IRF8
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	6	3,041,645 - 3,097,406 (-)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	6	3,041,617 - 3,060,685 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	6	3,343,491 - 3,358,042 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3
Pig Cytomap	6	p15-p14	NCBI

IRF8
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	5	71,301,878 - 71,325,622 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	5	71,302,233 - 71,325,613 (+)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666047	4,408,156 - 4,432,299 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Irf8
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624746	2,272,389 - 2,290,455 (+)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624746	2,272,385 - 2,290,400 (+)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Expression

Sequence

Nucleotide Sequences


RefSeq Transcripts	XM_005410985	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_013507991	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AGCD01071367	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	GBDF01090291	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

RefSeq Acc Id:

ENSCLAT00000002027 ⟹ ENSCLAP00000001982

Type:

CODING

Position:

Chinchilla Assembly	Chr	Position (strand)	Source
ChiLan1.0 Ensembl	NW_004955541	973,022 - 990,106 (+)	Ensembl

RefSeq Acc Id:

XM_005410985 ⟹ XP_005411042

Type:

CODING

Position:

Chinchilla Assembly	Chr	Position (strand)	Source
ChiLan1.0	NW_004955541	973,012 - 988,493 (+)	NCBI

Sequence:

show sequence

TTTTCTGCAGCTGCAACTCGTTCTCCTCCTCACCCACTGTTCCTCATGGCTCGCTCAGCGTCCC
CAGGAAGAGAGTAACCACCTCTGTGAGCCAAGGAGTCTTCTAAGGCCCAGCCTCGGCTCAGGCG
CTACTACCTGTGCAGCACCTGGACTCTCACTGCACCTCCGCCAGGATGTGTGACAGGAATGGCG
GACGGCGGCTGCGGCAGTGGCTGATTGAACAGATCGACAGCAACCTGTACCCGGGGCTGATCTG
GGAAAATGAGGAGAAGAGCATGTTCCGGATCCCCTGGAAGCACGCCGGCAAGCAGGACTACAAC
CAGGAGGTGGATGCCTCCATCTTCAAGGCCTGGGCAGTTTTTAAAGGGAAGTTTAAAGAAGGGG
ACAAAGCTGAACCAGCCACTTGGAAGACGAGGTTACGCTGTGCTTTGAACAAGAGCCCAGATTT
TGAGGAAGTGACAGACCGATCCCAGCTGGACATTTCCGAGCCGTACAAAGTTTACAGAATCGTC
CCGGAGGAAGAACAAAAATGCAAACTGGGCATCATGCCTCCCGGATGTGTGAGTGAGGTGGCGG
AGATGGAGTGCAGCCGCGCTGAGGTGGACGAGATGATCAAAGAGCAGCCTCCTGTGGACGACTA
CATGGGGATGATCAAGAGGAGCCCGTCCCCGCCAGAGGCCTGCAGGAGCCAGCTCCTCCCAGAC
TGGTGGGTGCCGCAGCCCAGCGCAGGCTTGCCGCTGGTGACCGGGTACCCCGCCTATGACCCAC
ACCATGCAGCCTTCTCCCAGATGGTGATCAGCTTCTACTATGGGGGCAAGCTGGTGGGCCAGGC
CACCACCACCTGCCCTGAGGGCTGTCGCCTGGCCCTGGGCCCGCCGGGGCTGCCCAGCGCCAAG
CTGTACGGGCCCGAGGGCCTGGAGCTGGTCCGCTTCCCGCCGGCCGACACCATCCCCAGCGAGC
GGCAGAGGCAGGTGACGCGGAAGCTGTTTGGGCACCTGGAGCGAGGGGTGCTCCTGCACAGCAG
CCGCCAGGGCGTGTTCGTCAAGCGGCTGTGCCAGGGCCGCGTGTTCTGCAGCGGCAATGCCGTG
GTGTGCAAGGGCAGACCCAACAAGCTGGAGCGCGACGAGGTGGTCCAGGTCTTTGACACCAGCC
AGTTCTTCCGAGAGCTGCAGCAGTTCTACGGCAGCCAGAGCCGCCTGCCCGACAGCAGGGTGGT
GCTGTGCTTCGGGGAGGAGTTTCCGGACATGGCGCCCTTGCGCTCCAAGCTCATCCTGGTGCAG
GTGGAGCAGCTGTACGTCAAGCAGCTGGTGGAGGACTCGGGGAAGAGCTGCACCGCGAGCTCCG
TGCTGCCGGTGACCGAGGAGCCGCAGCTGGACCAGGCCTTCCGGATGTTTCCTGAGATTTGTGC
TTCACACCAGAGACCCTTTTTCAGAGAAAACCAGCAGATCACTGTCTAAGGGGCGTCTCTCCCC
GGCGCCCCACCCTGCGCGTGGCTCACCGGTCACAGTGACTGGCAAACGTGGACGCTGCGGCCGG
GGTGTTCCGCTGGCTGTGCGGCTGAGGAGCCTGTGCTGGGCACAGTTGGGCCACAGTTCTGTTC
GCTCAGGAGGTGGGAACTTTCGGACAGTGGCCTGGATCCTGTAAAATTGTAACCTGAGATTAAA
AATTGTATTTTCTGCA

hide sequence

RefSeq Acc Id:

XM_013507991 ⟹ XP_013363445

Type:

CODING

Position:

Chinchilla Assembly	Chr	Position (strand)	Source
ChiLan1.0	NW_004955541	973,004 - 988,493 (+)	NCBI

Sequence:

show sequence

GACCTGGCTTTTCTGCAGCTGCAACTCGTTCTCCTCCTCACCCACTGTTCCTCATGGCTCGCTC
AGCGTCCCCAGGAAGAGAGTAACCACCTCTGTGAGCCAAGGAGTCTTCTAAGGCCCAGCCTCGG
CTCAGGCGCTACTACCTGTGCAGCACCTGGACTCTCACTGCACCTCCGCCAGGATGTGTGACAG
GAATGGCGGACGGCGGCTGCGGCAGTGGCTGATTGAACAGATCGACAGCAACCTGTACCCGGGG
CTGATCTGGGAAAATGAGGAGAAGAGCATGTTCCGGATCCCCTGGAAGCACGCCGGCAAGCAGG
ACTACAACCAGGAGGTGGATGCCTCCATCTTCAAGGCCTGGGCAGTTTTTAAAGGGAAGTTTAA
AGAAGGGGACAAAGCTGAACCAGCCACTTGGAAGACGAGGTTACGCTGTGCTTTGAACAAGAGC
CCAGATTTTGAGGAAGTGACAGACCGATCCCAGCTGGACATTTCCGAGCCGTACAAAGTTTACA
GAATCGTCCCGGAGGAAGAACAAAAATGCAAACTGGGCATCATGCCTCCCGGATGTGTGAGTGA
GGTGGCGGAGATGGAGTGCAGCCGCGCTGAGGTGGACGAGATGATCAAAGAGCCTCCTGTGGAC
GACTACATGGGGATGATCAAGAGGAGCCCGTCCCCGCCAGAGGCCTGCAGGAGCCAGCTCCTCC
CAGACTGGTGGGTGCCGCAGCCCAGCGCAGGCTTGCCGCTGGTGACCGGGTACCCCGCCTATGA
CCCACACCATGCAGCCTTCTCCCAGATGGTGATCAGCTTCTACTATGGGGGCAAGCTGGTGGGC
CAGGCCACCACCACCTGCCCTGAGGGCTGTCGCCTGGCCCTGGGCCCGCCGGGGCTGCCCAGCG
CCAAGCTGTACGGGCCCGAGGGCCTGGAGCTGGTCCGCTTCCCGCCGGCCGACACCATCCCCAG
CGAGCGGCAGAGGCAGGTGACGCGGAAGCTGTTTGGGCACCTGGAGCGAGGGGTGCTCCTGCAC
AGCAGCCGCCAGGGCGTGTTCGTCAAGCGGCTGTGCCAGGGCCGCGTGTTCTGCAGCGGCAATG
CCGTGGTGTGCAAGGGCAGACCCAACAAGCTGGAGCGCGACGAGGTGGTCCAGGTCTTTGACAC
CAGCCAGTTCTTCCGAGAGCTGCAGCAGTTCTACGGCAGCCAGAGCCGCCTGCCCGACAGCAGG
GTGGTGCTGTGCTTCGGGGAGGAGTTTCCGGACATGGCGCCCTTGCGCTCCAAGCTCATCCTGG
TGCAGGTGGAGCAGCTGTACGTCAAGCAGCTGGTGGAGGACTCGGGGAAGAGCTGCACCGCGAG
CTCCGTGCTGCCGGTGACCGAGGAGCCGCAGCTGGACCAGGCCTTCCGGATGTTTCCTGAGATT
TGTGCTTCACACCAGAGACCCTTTTTCAGAGAAAACCAGCAGATCACTGTCTAAGGGGCGTCTC
TCCCCGGCGCCCCACCCTGCGCGTGGCTCACCGGTCACAGTGACTGGCAAACGTGGACGCTGCG
GCCGGGGTGTTCCGCTGGCTGTGCGGCTGAGGAGCCTGTGCTGGGCACAGTTGGGCCACAGTTC
TGTTCGCTCAGGAGGTGGGAACTTTCGGACAGTGGCCTGGATCCTGTAAAATTGTAACCTGAGA
TTAAAAATTGTATTTTCTGCA

hide sequence

Protein Sequences


Protein RefSeqs	XP_005411042	(Get FASTA)	NCBI Sequence Viewer
	XP_013363445	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSCLAP00000001982
	ENSCLAP00000001982.1

RefSeq Acc Id:	XP_005411042 ⟸ XM_005410985
- Peptide Label:	isoform X1
- UniProtKB:	A0A8C2UNE9 (UniProtKB/TrEMBL)
- Sequence:	show sequence MCDRNGGRRLRQWLIEQIDSNLYPGLIWENEEKSMFRIPWKHAGKQDYNQEVDASIFKAWAVFK GKFKEGDKAEPATWKTRLRCALNKSPDFEEVTDRSQLDISEPYKVYRIVPEEEQKCKLGIMPPG CVSEVAEMECSRAEVDEMIKEQPPVDDYMGMIKRSPSPPEACRSQLLPDWWVPQPSAGLPLVTG YPAYDPHHAAFSQMVISFYYGGKLVGQATTTCPEGCRLALGPPGLPSAKLYGPEGLELVRFPPA DTIPSERQRQVTRKLFGHLERGVLLHSSRQGVFVKRLCQGRVFCSGNAVVCKGRPNKLERDEVV QVFDTSQFFRELQQFYGSQSRLPDSRVVLCFGEEFPDMAPLRSKLILVQVEQLYVKQLVEDSGK SCTASSVLPVTEEPQLDQAFRMFPEICASHQRPFFRENQQITV hide sequence

RefSeq Acc Id:

XP_013363445 ⟸ XM_013507991

- Peptide Label:

isoform X2

- Sequence:

show sequence

MCDRNGGRRLRQWLIEQIDSNLYPGLIWENEEKSMFRIPWKHAGKQDYNQEVDASIFKAWAVFK
GKFKEGDKAEPATWKTRLRCALNKSPDFEEVTDRSQLDISEPYKVYRIVPEEEQKCKLGIMPPG
CVSEVAEMECSRAEVDEMIKEPPVDDYMGMIKRSPSPPEACRSQLLPDWWVPQPSAGLPLVTGY
PAYDPHHAAFSQMVISFYYGGKLVGQATTTCPEGCRLALGPPGLPSAKLYGPEGLELVRFPPAD
TIPSERQRQVTRKLFGHLERGVLLHSSRQGVFVKRLCQGRVFCSGNAVVCKGRPNKLERDEVVQ
VFDTSQFFRELQQFYGSQSRLPDSRVVLCFGEEFPDMAPLRSKLILVQVEQLYVKQLVEDSGKS
CTASSVLPVTEEPQLDQAFRMFPEICASHQRPFFRENQQITV

hide sequence

RefSeq Acc Id:

ENSCLAP00000001982 ⟸ ENSCLAT00000002027

Protein Domains

IRF tryptophan pentad repeat

Additional Information

External Database Links

Database	Acc Id	Source(s)
Ensembl Genes	ENSCLAG00000001452	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSCLAT00000002027	ENTREZGENE
	ENSCLAT00000002027.1	UniProtKB/TrEMBL
Gene3D-CATH	1.10.10.10	UniProtKB/TrEMBL
	2.60.200.10	UniProtKB/TrEMBL
InterPro	Interferon_reg_fac_CS	UniProtKB/TrEMBL
	Interferon_reg_fact_DNA-bd_dom	UniProtKB/TrEMBL
	Interferon_reg_factor-3	UniProtKB/TrEMBL
	SMAD-like_dom_sf	UniProtKB/TrEMBL
	SMAD_FHA_dom_sf	UniProtKB/TrEMBL
	WH-like_DNA-bd_sf	UniProtKB/TrEMBL
	WH_DNA-bd_sf	UniProtKB/TrEMBL
NCBI Gene	Irf8	ENTREZGENE
PANTHER	INTERFERON REGULATORY FACTOR	UniProtKB/TrEMBL
	PTHR11949:SF7	UniProtKB/TrEMBL
Pfam	IRF	UniProtKB/TrEMBL
	IRF-3	UniProtKB/TrEMBL
PRINTS	INTFRNREGFCT	UniProtKB/TrEMBL
PROSITE	IRF_1	UniProtKB/TrEMBL
	IRF_2	UniProtKB/TrEMBL
SMART	IRF	UniProtKB/TrEMBL
	IRF-3	UniProtKB/TrEMBL
Superfamily-SCOP	SSF46785	UniProtKB/TrEMBL
	SSF49879	UniProtKB/TrEMBL
UniProt	A0A8C2UNE9	ENTREZGENE, UniProtKB/TrEMBL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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Imported Disease Annotations - CTD

Imported Disease Annotations - MGI

Imported Disease Annotations - OMIM

Imported Annotations - PID (archival)

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Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD

Imported Disease Annotations - MGI

Imported Disease Annotations - OMIM

Imported Annotations - PID (archival)