Spin4 (spindlin family member 4) - Rat Genome Database

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Gene: Spin4 (spindlin family member 4) Chinchilla lanigera
Analyze
Symbol: Spin4
Name: spindlin family member 4
RGD ID: 8967142
Description: ENCODES a protein that exhibits methylated histone binding (ortholog); INVOLVED IN negative regulation of cell population proliferation (ortholog); positive regulation of canonical Wnt signaling pathway (ortholog); ASSOCIATED WITH autistic disorder (ortholog); genetic disease (ortholog); osteopathia striata with cranial sclerosis (ortholog); FOUND IN chromatin (ortholog); cytoplasm (ortholog); nucleus (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: spindlin family, member 4; spindlin-4
RGD Orthologs
Human
Mouse
Rat
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: ChiLan1.0 - Chinchilla ChiLan1.0 Assembly
Position:
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554753,970,481 - 3,971,230 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554753,967,813 - 3,971,725 (-)NCBIChiLan1.0ChiLan1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
chromatin  (ISO)
cytoplasm  (ISO)
nucleus  (ISO)

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Transitive Annotation Pipeline Automated assignment of GO, PW and RDO ISO annotations across species
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Spin4
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554753,970,481 - 3,971,230 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554753,967,813 - 3,971,725 (-)NCBIChiLan1.0ChiLan1.0
SPIN4
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38X63,347,228 - 63,351,332 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 EnsemblX63,347,228 - 63,351,332 (-)EnsemblGRCh38hg38GRCh38
GRCh37X62,567,107 - 62,571,211 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36X62,483,832 - 62,487,943 (-)NCBINCBI36Build 36hg18NCBI36
CeleraX62,913,949 - 62,918,060 (-)NCBICelera
Cytogenetic MapXq11.1NCBI
HuRefX56,393,952 - 56,398,063 (-)NCBIHuRef
CHM1_1X62,459,711 - 62,463,822 (-)NCBICHM1_1
T2T-CHM13v2.0X61,772,497 - 61,776,601 (-)NCBIT2T-CHM13v2.0
Spin4
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39X94,066,113 - 94,070,288 (-)NCBIGRCm39GRCm39mm39
GRCm39 EnsemblX94,066,116 - 94,070,288 (-)EnsemblGRCm39 Ensembl
GRCm38X95,022,507 - 95,026,682 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 EnsemblX95,022,510 - 95,026,682 (-)EnsemblGRCm38mm10GRCm38
MGSCv37X92,217,846 - 92,222,021 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36X91,225,229 - 91,229,401 (-)NCBIMGSCv36mm8
CeleraX82,046,345 - 82,050,536 (-)NCBICelera
Cytogenetic MapXC3NCBI
cM MapX41.83NCBI
Spin4
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8X63,898,338 - 63,902,427 (-)NCBIGRCr8
mRatBN7.2X59,888,728 - 59,892,817 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 EnsemblX59,891,581 - 59,892,330 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_UtxX61,359,427 - 61,363,518 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0X64,859,949 - 64,864,040 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0X62,438,155 - 62,442,244 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0X64,217,074 - 64,221,225 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 EnsemblX64,219,933 - 64,220,593 (-)NCBIRnor6.0rn6Rnor6.0
Rnor_5.0X65,118,212 - 65,123,811 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4X82,564,580 - 82,565,329 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
CeleraX60,320,231 - 60,324,382 (-)NCBICelera
Cytogenetic MapXq22NCBI
SPIN4
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2X62,898,091 - 63,113,996 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1X62,900,023 - 63,117,594 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0X52,489,880 - 52,494,902 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1X62,502,776 - 62,506,934 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 EnsemblX62,505,610 - 62,506,359 (-)Ensemblpanpan1.1panPan2
SPIN4
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1X48,805,292 - 48,809,546 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 EnsemblX48,808,215 - 48,808,964 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_TashaX39,675,781 - 39,680,076 (+)NCBIDog10K_Boxer_Tasha
Spin4
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2X53,602,203 - 53,606,366 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366354,368,491 - 4,369,240 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049366354,367,956 - 4,369,768 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
SPIN4
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 EnsemblX49,976,950 - 49,981,084 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1X49,976,956 - 49,981,312 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
SPIN4
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1X53,601,474 - 53,605,617 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 EnsemblX53,604,335 - 53,605,081 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666083820,332 - 824,461 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Spin4
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248983,525,469 - 3,526,218 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248983,524,809 - 3,528,954 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts XM_005401549 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AGCD01054863 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSCLAT00000025744   ⟹   ENSCLAP00000025487
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_0049554753,970,481 - 3,971,230 (-)Ensembl
RefSeq Acc Id: XM_005401549   ⟹   XP_005401606
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_0049554753,967,813 - 3,971,725 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_005401606 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSCLAP00000025487
  ENSCLAP00000025487.1
Reference Protein Sequences
RefSeq Acc Id: XP_005401606   ⟸   XM_005401549
- UniProtKB: A0A8C2W7N9 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSCLAP00000025487   ⟸   ENSCLAT00000025744


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCLAG00000017570 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCLAT00000025744 ENTREZGENE
  ENSCLAT00000025744.1 UniProtKB/TrEMBL
Gene3D-CATH 2.80.10.70 UniProtKB/TrEMBL
InterPro SPIN/Ssty UniProtKB/TrEMBL
  SPIN/Ssty_sf UniProtKB/TrEMBL
NCBI Gene Spin4 ENTREZGENE
PANTHER PTHR10405 UniProtKB/TrEMBL
  PTHR10405:SF9 UniProtKB/TrEMBL
Pfam Spin-Ssty UniProtKB/TrEMBL
UniProt A0A8C2W7N9 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-08-16 Spin4  spindlin family member 4    spindlin family, member 4  Symbol and/or name change 5135510 APPROVED