Ptprk (protein tyrosine phosphatase receptor type K) - Rat Genome Database

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Gene: Ptprk (protein tyrosine phosphatase receptor type K) Chinchilla lanigera
Analyze
Symbol: Ptprk
Name: protein tyrosine phosphatase receptor type K
RGD ID: 8966638
Description: ENCODES a protein that exhibits beta-catenin binding (ortholog); gamma-catenin binding (ortholog); protein kinase binding (ortholog); INVOLVED IN cell adhesion (ortholog); cell migration (ortholog); cellular response to reactive oxygen species (ortholog); ASSOCIATED WITH genetic disease (ortholog); hereditary breast ovarian cancer syndrome (ortholog); melanoma (ortholog); FOUND IN axon (ortholog); cell junction (ortholog); cell surface (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: receptor-type tyrosine-protein phosphatase kappa
RGD Orthologs
Human
Mouse
Rat
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: ChiLan1.0 - Chinchilla ChiLan1.0 Assembly
Position:
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554368,975,554 - 9,380,971 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554368,975,742 - 9,371,608 (-)NCBIChiLan1.0ChiLan1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Transitive Annotation Pipeline Automated assignment of GO, PW and RDO ISO annotations across species
Additional References at PubMed
PMID:22301074  


Genomics

Comparative Map Data
Ptprk
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554368,975,554 - 9,380,971 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554368,975,742 - 9,371,608 (-)NCBIChiLan1.0ChiLan1.0
PTPRK
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh386127,968,785 - 128,520,599 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl6127,968,785 - 128,520,616 (-)EnsemblGRCh38hg38GRCh38
GRCh376128,289,930 - 128,841,744 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 366128,331,625 - 128,883,416 (-)NCBINCBI36Build 36hg18NCBI36
Build 346128,331,624 - 128,883,416NCBI
Celera6129,032,183 - 129,588,206 (-)NCBICelera
Cytogenetic Map6q22.33NCBI
HuRef6125,866,873 - 126,423,070 (-)NCBIHuRef
CHM1_16128,554,184 - 129,106,304 (-)NCBICHM1_1
T2T-CHM13v2.06129,157,761 - 129,713,738 (-)NCBIT2T-CHM13v2.0
Ptprk
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391027,950,406 - 28,473,393 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1027,950,816 - 28,473,393 (+)EnsemblGRCm39 Ensembl
GRCm381028,074,820 - 28,597,397 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1028,074,820 - 28,597,397 (+)EnsemblGRCm38mm10GRCm38
MGSCv371027,794,626 - 28,317,203 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361027,764,236 - 28,285,656 (+)NCBIMGSCv36mm8
Celera1028,989,399 - 29,512,323 (+)NCBICelera
Cytogenetic Map10A4NCBI
cM Map1015.06NCBI
Ptprk
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8118,557,091 - 19,056,297 (-)NCBIGRCr8
mRatBN7.2116,738,896 - 17,236,687 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl116,850,576 - 17,103,605 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx116,509,656 - 17,007,437 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0122,511,543 - 23,009,344 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0116,710,255 - 17,208,405 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0117,445,052 - 18,058,266 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl117,446,417 - 18,058,055 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0119,260,651 - 19,574,958 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Rnor_5.0118,602,550 - 18,714,238 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4117,328,563 - 17,752,200 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1117,332,345 - 17,752,187 (-)NCBI
Celera115,151,226 - 15,646,653 (-)NCBICelera
Cytogenetic Map1p12NCBI
PTPRK
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v25147,959,554 - 148,521,864 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan16145,868,253 - 146,426,592 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v06125,753,656 - 126,312,124 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.16129,864,573 - 130,421,909 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl6129,864,573 - 130,421,644 (-)Ensemblpanpan1.1panPan2
PTPRK
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1166,596,659 - 67,022,631 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl166,597,563 - 67,124,540 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha167,338,192 - 67,890,229 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0166,803,917 - 67,357,303 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl166,804,293 - 67,357,612 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1166,734,112 - 67,280,517 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0166,516,991 - 67,063,682 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0167,160,079 - 67,706,400 (-)NCBIUU_Cfam_GSD_1.0
Ptprk
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024404946116,735,448 - 117,236,710 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366391,278,808 - 1,682,279 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049366391,279,795 - 1,683,944 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
PTPRK
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl134,693,368 - 35,258,699 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1134,693,363 - 35,258,699 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2138,212,995 - 38,839,894 (+)NCBISscrofa10.2Sscrofa10.2susScr3
PTPRK
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11345,062,273 - 45,619,939 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1345,062,342 - 45,619,929 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604017,264,251 - 17,849,504 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Ptprk
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247532,357,680 - 2,877,981 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247532,357,800 - 2,878,176 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSCLAT00000023630   ⟹   ENSCLAP00000023409
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_0049554368,975,554 - 9,380,971 (-)Ensembl
RefSeq Acc Id: ENSCLAT00000023631   ⟹   ENSCLAP00000023410
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_0049554368,975,554 - 9,380,971 (-)Ensembl
RefSeq Acc Id: ENSCLAT00000023632   ⟹   ENSCLAP00000023411
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_0049554368,977,158 - 9,371,635 (-)Ensembl
RefSeq Acc Id: XM_013516643   ⟹   XP_013372097
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_0049554368,975,742 - 9,371,608 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_013372097 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSCLAP00000023409
  ENSCLAP00000023409.1
  ENSCLAP00000023410.1
  ENSCLAP00000023411.1
Reference Protein Sequences
RefSeq Acc Id: XP_013372097   ⟸   XM_013516643
- UniProtKB: A0A8C2W0L5 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSCLAP00000023411   ⟸   ENSCLAT00000023632
RefSeq Acc Id: ENSCLAP00000023409   ⟸   ENSCLAT00000023630
RefSeq Acc Id: ENSCLAP00000023410   ⟸   ENSCLAT00000023631
Protein Domains
Fibronectin type-III   Ig-like   MAM   Tyrosine specific protein phosphatases   Tyrosine-protein phosphatase


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCLAG00000016053 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCLAT00000023630 ENTREZGENE
  ENSCLAT00000023630.1 UniProtKB/TrEMBL
  ENSCLAT00000023631.1 UniProtKB/TrEMBL
  ENSCLAT00000023632.1 UniProtKB/TrEMBL
Gene3D-CATH 2.60.120.200 UniProtKB/TrEMBL
  2.60.40.10 UniProtKB/TrEMBL
  3.90.190.10 UniProtKB/TrEMBL
InterPro ConA-like_dom_sf UniProtKB/TrEMBL
  FN3_dom UniProtKB/TrEMBL
  FN3_sf UniProtKB/TrEMBL
  Ig-like_dom UniProtKB/TrEMBL
  Ig-like_dom_sf UniProtKB/TrEMBL
  Ig-like_fold UniProtKB/TrEMBL
  Ig_I-set UniProtKB/TrEMBL
  Ig_sub UniProtKB/TrEMBL
  MAM_dom UniProtKB/TrEMBL
  Prot-tyrosine_phosphatase-like UniProtKB/TrEMBL
  PTP_cat UniProtKB/TrEMBL
  Tyr_Pase_AS UniProtKB/TrEMBL
  Tyr_Pase_cat UniProtKB/TrEMBL
  Tyr_Pase_dom UniProtKB/TrEMBL
NCBI Gene Ptprk ENTREZGENE
PANTHER PROTEIN-TYROSINE-PHOSPHATASE UniProtKB/TrEMBL
  SUSHI DOMAIN-CONTAINING PROTEIN 1 UniProtKB/TrEMBL
Pfam fn3 UniProtKB/TrEMBL
  I-set UniProtKB/TrEMBL
  MAM UniProtKB/TrEMBL
  Y_phosphatase UniProtKB/TrEMBL
PRINTS MAMDOMAIN UniProtKB/TrEMBL
  PRTYPHPHTASE UniProtKB/TrEMBL
PROSITE FN3 UniProtKB/TrEMBL
  IG_LIKE UniProtKB/TrEMBL
  MAM_1 UniProtKB/TrEMBL
  MAM_2 UniProtKB/TrEMBL
  TYR_PHOSPHATASE_1 UniProtKB/TrEMBL
  TYR_PHOSPHATASE_2 UniProtKB/TrEMBL
  TYR_PHOSPHATASE_PTP UniProtKB/TrEMBL
SMART FN3 UniProtKB/TrEMBL
  MAM UniProtKB/TrEMBL
  PTPc UniProtKB/TrEMBL
  PTPc_motif UniProtKB/TrEMBL
  SM00409 UniProtKB/TrEMBL
Superfamily-SCOP SSF48726 UniProtKB/TrEMBL
  SSF49265 UniProtKB/TrEMBL
  SSF49899 UniProtKB/TrEMBL
  SSF52799 UniProtKB/TrEMBL
UniProt A0A8C2W0L5 ENTREZGENE, UniProtKB/TrEMBL
  A0A8C2W2S4_CHILA UniProtKB/TrEMBL
  A0A8C2W8G7_CHILA UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2019-02-19 Ptprk  protein tyrosine phosphatase receptor type K    protein tyrosine phosphatase, receptor type K  Symbol and/or name change 5135510 APPROVED
2016-08-03 Ptprk  protein tyrosine phosphatase, receptor type K    protein tyrosine phosphatase, receptor type, K  Symbol and/or name change 5135510 APPROVED