Uhrf2 (ubiquitin like with PHD and ring finger domains 2) - Rat Genome Database

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Gene: Uhrf2 (ubiquitin like with PHD and ring finger domains 2) Chinchilla lanigera
Analyze
Symbol: Uhrf2
Name: ubiquitin like with PHD and ring finger domains 2
RGD ID: 8965369
Description: ENCODES a protein that exhibits histone binding (ortholog); RNA polymerase II-specific DNA-binding transcription factor binding (ortholog); SUMO transferase activity (ortholog); INVOLVED IN cell differentiation (ortholog); protein autoubiquitination (ortholog); protein ubiquitination (ortholog); PARTICIPATES IN DNA modification pathway; ASSOCIATED WITH chromosome 9p deletion syndrome (ortholog); genetic disease (ortholog); FOUND IN heterochromatin (ortholog); nucleoplasm (ortholog); nucleus (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: E3 ubiquitin-protein ligase UHRF2; ubiquitin-like with PHD and ring finger domains 2, E3 ubiquitin protein ligase
RGD Orthologs
Human
Mouse
Rat
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: ChiLan1.0 - Chinchilla ChiLan1.0 Assembly
NCBI Annotation Information: Annotation category: partial on reference assembly
Position:
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495543410,337,564 - 10,413,290 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495543410,337,871 - 10,413,290 (+)NCBIChiLan1.0ChiLan1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Transitive Annotation Pipeline Automated assignment of GO, PW and RDO ISO annotations across species
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Uhrf2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495543410,337,564 - 10,413,290 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495543410,337,871 - 10,413,290 (+)NCBIChiLan1.0ChiLan1.0
UHRF2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh3896,413,199 - 6,507,054 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl96,413,151 - 6,507,054 (+)EnsemblGRCh38hg38GRCh38
GRCh3796,413,199 - 6,507,054 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 3696,403,151 - 6,497,051 (+)NCBINCBI36Build 36hg18NCBI36
Celera96,350,611 - 6,444,524 (+)NCBICelera
Cytogenetic Map9p24.1NCBI
HuRef96,368,448 - 6,462,031 (+)NCBIHuRef
CHM1_196,413,916 - 6,507,825 (+)NCBICHM1_1
T2T-CHM13v2.096,418,255 - 6,512,105 (+)NCBIT2T-CHM13v2.0
Uhrf2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391930,007,920 - 30,071,126 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1930,007,913 - 30,071,122 (+)EnsemblGRCm39 Ensembl
GRCm381930,030,430 - 30,093,726 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1930,030,513 - 30,093,722 (+)EnsemblGRCm38mm10GRCm38
MGSCv371930,105,003 - 30,168,216 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361930,096,600 - 30,159,723 (+)NCBIMGSCv36mm8
Celera1930,805,906 - 30,868,941 (+)NCBICelera
Cytogenetic Map19C1NCBI
cM Map1924.73NCBI
Uhrf2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81237,224,050 - 237,291,406 (+)NCBIGRCr8
mRatBN7.21227,814,639 - 227,877,907 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1227,814,963 - 227,877,904 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1236,216,934 - 236,279,927 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01243,146,619 - 243,209,613 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01235,968,772 - 236,031,886 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01248,228,496 - 248,291,984 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1248,228,496 - 248,291,978 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01255,476,029 - 255,539,517 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41233,777,723 - 233,841,343 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11233,941,745 - 234,005,366 (+)NCBI
Celera1224,961,724 - 225,024,651 (+)NCBICelera
Cytogenetic Map1q52NCBI
UHRF2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v211118,069,622 - 118,163,049 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan19118,075,570 - 118,168,985 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v096,228,895 - 6,322,319 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.196,409,081 - 6,502,484 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl96,409,081 - 6,502,484 (+)Ensemblpanpan1.1panPan2
UHRF2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11127,406,275 - 27,474,971 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1127,405,977 - 27,623,005 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1126,181,369 - 26,258,264 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01128,256,562 - 28,333,875 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1128,256,658 - 28,333,060 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11126,980,701 - 27,057,565 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01126,799,633 - 26,876,818 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01127,468,621 - 27,545,966 (+)NCBIUU_Cfam_GSD_1.0
Uhrf2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024404947142,457,520 - 142,537,571 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936539910,172 - 992,983 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936539910,191 - 990,258 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
UHRF2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1215,730,225 - 215,807,627 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11215,730,212 - 215,807,630 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21241,357,141 - 241,363,220 (-)NCBISscrofa10.2Sscrofa10.2susScr3
UHRF2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11273,010,697 - 73,106,163 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1273,007,830 - 73,106,120 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366603861,349,917 - 61,448,467 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Uhrf2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462473610,913,643 - 11,003,525 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462473610,901,260 - 11,004,832 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSCLAT00000006698   ⟹   ENSCLAP00000006589
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_00495543410,337,564 - 10,413,290 (+)Ensembl
RefSeq Acc Id: XM_013516354   ⟹   XP_013371808
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_00495543410,337,871 - 10,413,290 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_013371808 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSCLAP00000006589
  ENSCLAP00000006589.1
Reference Protein Sequences
RefSeq Acc Id: XP_013371808   ⟸   XM_013516354
- UniProtKB: A0A8C2V2B7 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSCLAP00000006589   ⟸   ENSCLAT00000006698
Protein Domains
PHD-type   RING-type   YDG


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCLAG00000004646 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCLAT00000006698 ENTREZGENE
  ENSCLAT00000006698.1 UniProtKB/TrEMBL
Gene3D-CATH 2.30.280.10 UniProtKB/TrEMBL
  2.30.30.1150 UniProtKB/TrEMBL
  2.30.30.140 UniProtKB/TrEMBL
  3.30.40.10 UniProtKB/TrEMBL
InterPro PHD_UHRF2 UniProtKB/TrEMBL
  PUA-like_sf UniProtKB/TrEMBL
  RING-HC_UHRF2 UniProtKB/TrEMBL
  SRA-YDG_sf UniProtKB/TrEMBL
  SRA_YDG UniProtKB/TrEMBL
  TTD_dom UniProtKB/TrEMBL
  Tudor_UHRF2_rpt1 UniProtKB/TrEMBL
  UHRF1/2-like UniProtKB/TrEMBL
  Znf_FYVE_PHD UniProtKB/TrEMBL
  Znf_PHD UniProtKB/TrEMBL
  Znf_PHD-finger UniProtKB/TrEMBL
  Znf_RING UniProtKB/TrEMBL
  Znf_RING/FYVE/PHD UniProtKB/TrEMBL
  Znf_RING_CS UniProtKB/TrEMBL
NCBI Gene Uhrf2 ENTREZGENE
PANTHER E3 UBIQUITIN-PROTEIN LIGASE UHRF2 UniProtKB/TrEMBL
  PTHR14140 UniProtKB/TrEMBL
Pfam PHD UniProtKB/TrEMBL
  SAD_SRA UniProtKB/TrEMBL
  TTD UniProtKB/TrEMBL
PROSITE YDG UniProtKB/TrEMBL
  ZF_PHD_2 UniProtKB/TrEMBL
  ZF_RING_1 UniProtKB/TrEMBL
  ZF_RING_2 UniProtKB/TrEMBL
SMART PHD UniProtKB/TrEMBL
  RING UniProtKB/TrEMBL
  SRA UniProtKB/TrEMBL
Superfamily-SCOP RING/U-box UniProtKB/TrEMBL
  SSF57903 UniProtKB/TrEMBL
  SSF88697 UniProtKB/TrEMBL
UniProt A0A8C2V2B7 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-08-03 Uhrf2  ubiquitin like with PHD and ring finger domains 2    ubiquitin-like with PHD and ring finger domains 2, E3 ubiquitin protein ligase  Symbol and/or name change 5135510 APPROVED