Cnn3 (calponin 3) - Rat Genome Database

Name: Cnn3
Creator: Rat Genome Database
License: Creative Commons CC BY 4.0
Keywords: Rat Gene RGD Genome

Gene: Cnn3 (calponin 3) Chinchilla lanigera

Analyze

Symbol:

Cnn3

Name:

calponin 3

RGD ID:

8964319

Description:

ENCODES a protein that exhibits microtubule binding (ortholog); INVOLVED IN epithelial cell differentiation (ortholog); negative regulation of ATP-dependent activity (ortholog); ASSOCIATED WITH Animal Mammary Neoplasms (ortholog); carcinoma (ortholog); Experimental Mammary Neoplasms (ortholog); FOUND IN actin cytoskeleton (ortholog); cytosol (ortholog); dendrite (ortholog)

Type:

protein-coding

RefSeq Status:

MODEL

Previously known as:

calponin 3, acidic; calponin-3; UDP-N-acetylglucosamine transferase subunit ALG14 homolog

RGD Orthologs

Alliance Genes

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	CNN3 (calponin 3)	NCBI	Ortholog
Mus musculus (house mouse):	Cnn3 (calponin 3, acidic)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Rattus norvegicus (Norway rat):	Cnn3 (calponin 3)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	CNN3 (calponin 3)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	CNN3 (calponin 3)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Cnn3 (calponin 3)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	CNN3 (calponin 3)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	CNN3 (calponin 3)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Cnn3 (calponin 3)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline

Latest Assembly:

ChiLan1.0 - Chinchilla ChiLan1.0 Assembly

Position:

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955435	80,185 - 89,766 (-)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955435	80,185 - 89,216 (-)	NCBI	ChiLan1.0	ChiLan1.0

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

Animal Mammary Neoplasms (ISO)

carcinoma (ISO)

Experimental Mammary Neoplasms (ISO)

genetic disease (ISO)

Prostatic Neoplasms (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

epithelial cell differentiation (ISO)

negative regulation of ATP-dependent activity (ISO)

Cellular Component

actin cytoskeleton (ISO)

cytosol (ISO)

dendrite (ISO)

dendritic spine (ISO)

glutamatergic synapse (ISO)

neuronal cell body (ISO)

postsynapse (ISO)

Molecular Function

microtubule binding (ISO)

References

References - curated

#	Reference Title	Reference Citation
1.	Transitive Annotation Pipeline	Automated assignment of GO, PW and RDO ISO annotations across species

Additional References at PubMed

PMID:22301074

Genomics

Comparative Map Data

Cnn3
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955435	80,185 - 89,766 (-)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955435	80,185 - 89,216 (-)	NCBI	ChiLan1.0	ChiLan1.0

CNN3
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	1	94,896,957 - 94,927,110 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	1	94,896,949 - 94,927,223 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	1	95,362,513 - 95,392,666 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	1	95,135,095 - 95,165,289 (-)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	1	95,074,529 - 95,104,722	NCBI
Celera	1	93,616,973 - 93,647,200 (-)	NCBI		Celera
Cytogenetic Map	1	p21.3	NCBI
HuRef	1	93,484,336 - 93,514,531 (-)	NCBI		HuRef
CHM1_1	1	95,477,311 - 95,507,534 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	1	94,745,314 - 94,775,463 (-)	NCBI		T2T-CHM13v2.0

Cnn3
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	3	121,220,190 - 121,251,854 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	3	121,220,146 - 121,251,856 (+)	Ensembl		GRCm39 Ensembl
GRCm38	3	121,426,541 - 121,458,205 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	3	121,426,497 - 121,458,207 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	3	121,129,459 - 121,161,123 (+)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	3	121,418,564 - 121,450,228 (+)	NCBI		MGSCv36	mm8
Celera	3	127,782,383 - 127,824,521 (+)	NCBI		Celera
Cytogenetic Map	3	G1	NCBI
cM Map	3	52.94	NCBI

Cnn3
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	2	212,203,661 - 212,234,772 (+)	NCBI		GRCr8
mRatBN7.2	2	209,518,948 - 209,550,107 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	2	209,518,948 - 209,550,104 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	2	217,181,924 - 217,213,028 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	2	215,089,643 - 215,120,749 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	2	209,931,377 - 209,962,475 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	2	225,005,069 - 225,036,179 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	2	225,005,019 - 225,036,188 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	2	243,044,080 - 243,075,234 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	2	218,044,803 - 218,075,914 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	2	218,007,864 - 218,038,976 (+)	NCBI
Celera	2	201,950,953 - 201,982,114 (+)	NCBI		Celera
Cytogenetic Map	2	q42	NCBI

CNN3
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	1	132,096,906 - 132,127,207 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	1	131,251,606 - 131,281,812 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	1	97,558,652 - 97,588,791 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	1	96,286,015 - 96,316,249 (-)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	1	96,286,015 - 96,316,249 (-)	Ensembl	panpan1.1		panPan2

CNN3
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	6	54,378,031 - 54,405,009 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	6	54,368,162 - 54,404,201 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	6	57,077,741 - 57,105,796 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	6	54,751,458 - 54,778,564 (+)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	6	54,743,775 - 54,778,564 (+)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	6	54,425,310 - 54,453,361 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	6	54,409,986 - 54,438,043 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	6	54,862,633 - 54,890,718 (+)	NCBI		UU_Cfam_GSD_1.0

Cnn3
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024405058	104,609,983 - 104,638,951 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936537	4,308,951 - 4,337,998 (+)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936537	4,308,951 - 4,337,990 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

CNN3
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	4	122,504,433 - 122,528,348 (+)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	4	122,504,450 - 122,528,351 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	4	134,245,269 - 134,269,263 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

CNN3
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	20	38,325,810 - 38,356,563 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	20	38,325,848 - 38,356,760 (+)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666033	79,710,142 - 79,740,641 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Cnn3
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624742	2,737,057 - 2,767,273 (+)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624742	2,737,131 - 2,767,026 (+)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Expression

Sequence

Nucleotide Sequences


RefSeq Transcripts	XM_013516526	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AGCD01032711	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AGCD01032712	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	GBBH01201043	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

RefSeq Acc Id:

ENSCLAT00000012442 ⟹ ENSCLAP00000012299

Type:

CODING

Position:

Chinchilla Assembly	Chr	Position (strand)	Source
ChiLan1.0 Ensembl	NW_004955435	80,185 - 89,216 (-)	Ensembl

RefSeq Acc Id:

ENSCLAT00000012443 ⟹ ENSCLAP00000012300

Type:

CODING

Position:

Chinchilla Assembly	Chr	Position (strand)	Source
ChiLan1.0 Ensembl	NW_004955435	80,939 - 89,766 (-)	Ensembl

RefSeq Acc Id:

ENSCLAT00000012444 ⟹ ENSCLAP00000012301

Type:

CODING

Position:

Chinchilla Assembly	Chr	Position (strand)	Source
ChiLan1.0 Ensembl	NW_004955435	80,939 - 89,197 (-)	Ensembl

RefSeq Acc Id:

XM_013516526 ⟹ XP_013371980

Type:

CODING

Position:

Chinchilla Assembly	Chr	Position (strand)	Source
ChiLan1.0	NW_004955435	80,185 - 89,216 (-)	NCBI

Sequence:

show sequence

AAATTAATGTACCTTTCAGATTGCTTCCAAGTATGACCACCAGGCGGAAGAAGACCTGCGCAAT
TGGATAGAAGAGGTGACAGGCATGAGCATTGGCACCAACTTCCAGCTGGGTCTGAAGGACGGCA
TCATTCTGTGCGAACTCATAAACAAGTTACAGCCAGGCTCTGTGAAGAAGGTCAATGAGTCTGC
ATTAAATTGGCCTCAGTTGGAAAATATTGGCAACTTCATTAAAGCTATTCAGGCTTATGGTATG
AAGCCACATGACATATTTGAAGCAAATGATCTTTTTGAGAATGGAAACATGACCCAGGTTCAGA
CTACACTGGTGGCTCTAGCGGGTCTGGCTAAAACAAAAGGGTTCCACACAACCATTGACATTGG
AGTTAAGTACGCAGAGAAACAAACAAGACGCTTTGATGAAGGAAAACTAAAGGCTGGCCAGAGT
GTAATTGGTTTGCAGATGGGAACAAACAAATGTGCCAGCCAGGCAGGCATGACAGCCTATGGAA
CTAGGAGGCATCTTTATGATCCCAAAATGCAAACTGACAAACCTTTTGATCAGACCACTATCAG
TCTGCAGATGGGCACCAACAAAGGAGCCAGCCAGGCGGGGATGTTAGCACCAGGCACCAGAAGA
GACATCTATGATCAGAAGCTAACATTACAGCCGGTAGACAACTCGACAATTTCCCTACAGATGG
GTACCAACAAAGTTGCTTCCCAGAAAGGAATGAGTGTGTATGGGCTTGGGCGGCAAGTGTATGA
TCCCAAGTACTGTGCAGCTCCGACAGAACCTGTCATTCACAATGGAAGCCAGGGCACAGGAACA
AATGGGTCGGAAATCAGTGATAGTGATTATCAGGCAGAATACCCAGATGAGTATCATGGCGAGT
ACCAAGATGACTACCCCAGAGATTACCAGTATGGTGACCAAGGCATTGATTATTAGATTCACAC
AGGAGCTCAGTATTTAGTCCATGATTTTTATTCAGTGAGAACCAAGCTAGCCTTGAGTAATTTC
TATCTTGTCTTCCTAAAACACTATTATGCTTATTGTACCTAAAAAAAATGCCTTACATACATTC
CTTTTTCTGCCTCTTCCCTAAATAGTTGCCTTTTAGTGCTGTAACAGTTAAATCCTACAGCATA
ACCAGTAACTTGCATATGAAGTAAAAAGGAACACTGTGAAAGGGGAGTACTCTTGTACAGCCAG
TTCTTTTATTGAAGATCTATGCATTTTTACAATCTTACACTTAAACTGGTATTTTCAAGCAATA
GGACATTTTCTTTTTTTACAGATTAGTGTATCTGGTTTCTACATGGAAGACTAAACTCATGCTT
ATTGCTAAATGTGGTCTTTGCCAACTAAACCTAAGATGCAGCATTTTAGAATTTTACATATCAA
TGTTTCTACAGTATTGTTTGCTAATTTTTAAATAAAGTCCTGATCAGTGTGCATTTGTGATTAT
ATGTGTACTCATTCTCTTACGCTGACAAGATGTTTTCAGAGTGGCATTTCTAAAGGAGCATGTA
CAAAAAGTGGCTTGCAGACATTCGGGTCTGGGTGGTGCAGTTGCAAAATGGTTTGTGCCAATGT
GTCATTGTAGAGTTGCTCTGTTTTCTTCAACTGTATTTATTGCTGCATTTCTCAGCATAAACTT
ATCCCATTGTATTTTTTATAAATAAATATTTTTTTGAACATT

hide sequence

Protein Sequences


Protein RefSeqs	XP_013371980	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSCLAP00000012299
	ENSCLAP00000012299.1
	ENSCLAP00000012300.1
	ENSCLAP00000012301.1

RefSeq Acc Id:

XP_013371980 ⟸ XM_013516526

- UniProtKB:

A0A8C2V9R3 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MSIGTNFQLGLKDGIILCELINKLQPGSVKKVNESALNWPQLENIGNFIKAIQAYGMKPHDIFE
ANDLFENGNMTQVQTTLVALAGLAKTKGFHTTIDIGVKYAEKQTRRFDEGKLKAGQSVIGLQMG
TNKCASQAGMTAYGTRRHLYDPKMQTDKPFDQTTISLQMGTNKGASQAGMLAPGTRRDIYDQKL
TLQPVDNSTISLQMGTNKVASQKGMSVYGLGRQVYDPKYCAAPTEPVIHNGSQGTGTNGSEISD
SDYQAEYPDEYHGEYQDDYPRDYQYGDQGIDY

hide sequence

RefSeq Acc Id:

ENSCLAP00000012299 ⟸ ENSCLAT00000012442

RefSeq Acc Id:

ENSCLAP00000012301 ⟸ ENSCLAT00000012444

RefSeq Acc Id:

ENSCLAP00000012300 ⟸ ENSCLAT00000012443

Protein Domains

Calponin-homology (CH)

Additional Information

External Database Links

Database	Acc Id	Source(s)
Ensembl Genes	ENSCLAG00000008495	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSCLAT00000012442	ENTREZGENE
	ENSCLAT00000012442.1	UniProtKB/TrEMBL
	ENSCLAT00000012443.1	UniProtKB/TrEMBL
	ENSCLAT00000012444.1	UniProtKB/TrEMBL
Gene3D-CATH	1.10.418.10	UniProtKB/TrEMBL
InterPro	Calponin/LIMCH1	UniProtKB/TrEMBL
	Calponin_repeat	UniProtKB/TrEMBL
	CH-domain	UniProtKB/TrEMBL
	CH_dom_sf	UniProtKB/TrEMBL
	SM22_calponin	UniProtKB/TrEMBL
NCBI Gene	LOC102022733	ENTREZGENE
PANTHER	CALPONIN	UniProtKB/TrEMBL
	CALPONIN	UniProtKB/TrEMBL
	CALPONIN-3	UniProtKB/TrEMBL
Pfam	Calponin	UniProtKB/TrEMBL
	PF00307	UniProtKB/TrEMBL
PRINTS	CALPONIN	UniProtKB/TrEMBL
	SM22CALPONIN	UniProtKB/TrEMBL
PROSITE	CALPONIN_1	UniProtKB/TrEMBL
	CALPONIN_2	UniProtKB/TrEMBL
	PS50021	UniProtKB/TrEMBL
SMART	SM00033	UniProtKB/TrEMBL
Superfamily-SCOP	SSF47576	UniProtKB/TrEMBL
UniProt	A0A8C2V9R3	ENTREZGENE, UniProtKB/TrEMBL
	A0A8C2YNT4_CHILA	UniProtKB/TrEMBL
	A0A8C2YNT9_CHILA	UniProtKB/TrEMBL

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2016-08-03	Cnn3	calponin 3		calponin 3, acidic	Symbol and/or name change	5135510	APPROVED
2015-08-25	Cnn3	calponin 3, acidic	LOC102022733	UDP-N-acetylglucosamine transferase subunit ALG14 homolog	Symbol and/or name change	5135510	APPROVED

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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