Mpo (myeloperoxidase) - Rat Genome Database
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Gene: Mpo (myeloperoxidase) Chinchilla lanigera
Analyze
Symbol: Mpo
Name: myeloperoxidase
RGD ID: 8957017
Description: ENCODES a protein that exhibits heparin binding (ortholog); peroxidase activity (ortholog); INVOLVED IN aging (ortholog); defense response to fungus (ortholog); hydrogen peroxide catabolic process (ortholog); PARTICIPATES IN etoposide pharmacodynamics pathway; etoposide pharmacokinetics pathway; interleukin-23 signaling pathway; ASSOCIATED WITH acute kidney failure (ortholog); Acute Lung Injury (ortholog); alcoholic liver cirrhosis (ortholog); FOUND IN azurophil granule (ortholog); extracellular space (ortholog); intracellular membrane-bounded organelle (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Orthologs:
Homo sapiens (human) : MPO (myeloperoxidase)  HGNC  Alliance
Mus musculus (house mouse) : Mpo (myeloperoxidase)  MGI  Alliance
Rattus norvegicus (Norway rat) : Mpo (myeloperoxidase)  Alliance
Pan paniscus (bonobo/pygmy chimpanzee) : MPO (myeloperoxidase)
Canis lupus familiaris (dog) : MPO (myeloperoxidase)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Mpo (myeloperoxidase)
Sus scrofa (pig) : MPO (myeloperoxidase)
Chlorocebus sabaeus (African green monkey) : MPO (myeloperoxidase)
Heterocephalus glaber (naked mole-rat) : Mpo (myeloperoxidase)
more info ...
Latest Assembly: ChiLan1.0 - Chinchilla ChiLan1.0 Assembly
Position:
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554514,743,744 - 4,753,358 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554514,743,744 - 4,753,358 (+)NCBIChiLan1.0ChiLan1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View
acute kidney failure  (ISO)
Acute Lung Injury  (ISO)
alcoholic liver cirrhosis  (ISO)
Alzheimer's disease  (ISO)
Alzheimer's disease 1  (ISO)
Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis  (ISO)
asthma  (ISO)
bacterial pneumonia  (ISO)
brain disease  (ISO)
Brain Injuries  (ISO)
Brain Injuries, Traumatic  (ISO)
brain ischemia  (ISO)
Burns  (ISO)
cardiovascular system disease  (ISO)
Chronic Bronchitis  (ISO)
chronic obstructive pulmonary disease  (ISO)
colitis  (ISO)
Contrast-Induced Nephropathy  (ISO)
cystic fibrosis  (ISO)
cystitis  (ISO)
Drug Eruptions  (ISO)
end stage renal disease  (ISO)
Enteritis  (ISO)
Experimental Arthritis  (ISO)
Experimental Diabetes Mellitus  (ISO)
extrahepatic cholestasis  (ISO)
glomerulonephritis  (ISO)
Hemorrhagic Shock  (ISO)
hepatocellular carcinoma  (ISO)
Hypoxia  (ISO)
Inflammation  (ISO)
interstitial lung disease  (ISO)
keratosis  (ISO)
Kidney Calculi  (ISO)
kidney disease  (ISO)
Kidney Reperfusion Injury  (ISO)
liver cirrhosis  (ISO)
lung cancer  (ISO)
lung disease  (ISO)
Lung Neoplasms  (ISO)
lupus nephritis  (ISO)
major depressive disorder  (ISO)
Myeloperoxidase Deficiency  (ISO)
Myocardial Ischemia  (ISO)
Occupational Diseases  (ISO)
pancreatic cancer  (ISO)
pancreatitis  (ISO)
pleurisy  (ISO)
pre-malignant neoplasm  (ISO)
Prostatic Neoplasms  (ISO)
renovascular hypertension  (ISO)
Reperfusion Injury  (ISO)
rheumatoid arthritis  (ISO)
Sepsis  (ISO)
Spinal Cord Injuries  (ISO)
status asthmaticus  (ISO)
trichuriasis  (ISO)
ulcerative colitis  (ISO)
urinary bladder cancer  (ISO)
urticaria  (ISO)
vasculitis  (ISO)
Viral Bronchiolitis  (ISO)
Wounds and Injuries  (ISO)

References


Genomics

Comparative Map Data
Mpo
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554514,743,744 - 4,753,358 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554514,743,744 - 4,753,358 (+)NCBIChiLan1.0ChiLan1.0
MPO
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl1758,269,855 - 58,280,935 (-)EnsemblGRCh38hg38GRCh38
GRCh381758,269,855 - 58,280,935 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh371756,347,217 - 56,358,296 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361753,702,216 - 53,713,295 (-)NCBINCBI36hg18NCBI36
Build 341753,702,215 - 53,713,295NCBI
Celera1752,808,995 - 52,820,066 (-)NCBI
Cytogenetic Map17q22NCBI
HuRef1751,708,013 - 51,718,966 (-)NCBIHuRef
CHM1_11756,412,238 - 56,423,315 (-)NCBICHM1_1
Mpo
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391187,684,610 - 87,695,238 (+)NCBI
GRCm381187,793,784 - 87,804,412 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1187,793,581 - 87,804,413 (+)EnsemblGRCm38mm10GRCm38
MGSCv371187,607,286 - 87,617,914 (+)NCBIGRCm37mm9NCBIm37
MGSCv361187,609,776 - 87,620,592 (+)NCBImm8
Celera1197,389,547 - 97,400,150 (+)NCBICelera
Cytogenetic Map11CNCBI
cM Map1152.22NCBI
Mpo
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01075,087,892 - 75,098,260 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1075,087,892 - 75,098,260 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01075,004,128 - 75,014,496 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41076,085,872 - 76,097,012 (+)NCBIRGSC3.4rn4RGSC3.4
Celera1071,507,771 - 71,517,382 (+)NCBICelera
Cytogenetic Map10q26NCBI
MPO
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.11757,189,654 - 57,212,111 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1757,201,073 - 57,212,111 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v01752,333,882 - 52,357,838 (-)NCBIMhudiblu_PPA_v0panPan3
MPO
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1 Ensembl932,927,483 - 32,937,820 (-)EnsemblCanFam3.1canFam3CanFam3.1
CanFam3.1932,927,483 - 32,938,007 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Mpo
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
SpeTri2.0NW_0049364904,809,773 - 4,819,070 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
MPO
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1234,556,408 - 34,567,904 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11234,557,031 - 34,570,091 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21236,245,391 - 36,256,372 (+)NCBISscrofa10.2Sscrofa10.2susScr3
MPO
(Chlorocebus sabaeus - African green monkey)
Vervet AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1 Ensembl1635,120,581 - 35,130,671 (+)Ensembl
ChlSab1.11635,120,194 - 35,130,851 (+)NCBI
Mpo
(Heterocephalus glaber - naked mole-rat)
Molerat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_004624871121,026 - 131,433 (-)NCBI


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSCLAT00000022750   ⟹   ENSCLAP00000022542
RefSeq Status:
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_0049554514,743,744 - 4,753,358 (+)Ensembl
RefSeq Acc Id: XM_005394030   ⟹   XP_005394087
RefSeq Status:
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_0049554514,743,744 - 4,753,358 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_005394087 (Get FASTA)   NCBI Sequence Viewer  
Reference Sequences
RefSeq Acc Id: XP_005394087   ⟸   XM_005394030
- Sequence:
RefSeq Acc Id: ENSCLAP00000022542   ⟸   ENSCLAT00000022750


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCLAG00000015465 Ensembl, ENTREZGENE
Ensembl Protein ENSCLAP00000022542 ENTREZGENE
Ensembl Transcript ENSCLAT00000022750 ENTREZGENE
NCBI Gene Mpo ENTREZGENE