Mthfs (methenyltetrahydrofolate synthetase) - Rat Genome Database

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Gene: Mthfs (methenyltetrahydrofolate synthetase) Chinchilla lanigera
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Symbol: Mthfs
Name: methenyltetrahydrofolate synthetase
RGD ID: 8956688
Description: ENCODES a protein that exhibits 5-formyltetrahydrofolate cyclo-ligase activity (ortholog); ATP binding (ortholog); folic acid binding (ortholog); INVOLVED IN folic acid catabolic process (ortholog); glutamate metabolic process (ortholog); tetrahydrofolate interconversion (ortholog); PARTICIPATES IN folate metabolic pathway; hereditary folate malabsorption pathway; methotrexate pharmacodynamics pathway; ASSOCIATED WITH Bloom syndrome (ortholog); cleft lip (ortholog); cleft palate (ortholog); FOUND IN cytoplasm (ortholog); cytosol (ortholog); mitochondrial matrix (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Also known as: 5,10-methenyltetrahydrofolate synthetase (5-formyltetrahydrofolate cyclo-ligase); 5-formyltetrahydrofolate cyclo-ligase
RGD Orthologs
Human
Mouse
Rat
Dog
Squirrel
Pig
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: ChiLan1.0 - Chinchilla ChiLan1.0 Assembly
NCBI Annotation Information: Annotation category: partial on reference assembly
Position:
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_004955533720,255 - 756,893 (-)NCBIChiLan1.0ChiLan1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References


Genomics

Comparative Map Data
Mthfs
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_004955533720,255 - 756,893 (-)NCBIChiLan1.0ChiLan1.0
MTHFS
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl1579,833,585 - 79,897,379 (-)EnsemblGRCh38hg38GRCh38
GRCh381579,843,547 - 79,897,285 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh371580,135,889 - 80,189,627 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361577,924,373 - 77,976,425 (-)NCBINCBI36hg18NCBI36
Build 341577,924,374 - 77,976,395NCBI
Celera1557,073,628 - 57,125,676 (-)NCBI
Cytogenetic Map15q25.1NCBI
HuRef1556,894,007 - 56,947,724 (-)NCBIHuRef
CHM1_11580,252,880 - 80,306,583 (-)NCBICHM1_1
Mthfs
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39989,093,243 - 89,122,278 (+)NCBIGRCm39mm39
GRCm39 Ensembl989,092,729 - 89,259,766 (+)Ensembl
GRCm38989,211,190 - 89,240,225 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl989,210,676 - 89,377,713 (+)EnsemblGRCm38mm10GRCm38
MGSCv37989,106,028 - 89,135,063 (+)NCBIGRCm37mm9NCBIm37
MGSCv36989,009,083 - 89,038,118 (+)NCBImm8
Celera988,839,126 - 88,843,217 (+)NCBICelera
Celera987,292,813 - 87,293,205 (+)NCBICelera
Cytogenetic Map9E3.1NCBI
Mthfs
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2889,729,498 - 89,801,998 (+)NCBImRatBN7.2
Rnor_6.0 Ensembl896,564,877 - 96,614,348 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.0896,564,877 - 96,614,386 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0896,071,796 - 96,121,086 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4894,058,605 - 94,108,277 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1894,078,059 - 94,127,729 (+)NCBI
Celera889,291,095 - 89,340,497 (+)NCBICelera
Cytogenetic Map8q31NCBI
MTHFS
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1357,480,935 - 57,514,836 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha360,139,116 - 60,173,501 (+)NCBI
ROS_Cfam_1.0357,913,790 - 57,950,014 (+)NCBI
UMICH_Zoey_3.1357,413,049 - 57,447,505 (+)NCBI
UNSW_CanFamBas_1.0357,620,059 - 57,654,466 (+)NCBI
UU_Cfam_GSD_1.0357,967,073 - 58,003,248 (+)NCBI
Mthfs
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024408640119,976,748 - 120,116,548 (-)NCBI
SpeTri2.0NW_00493647137,910,856 - 37,964,655 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
LOC102167410
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1748,717,518 - 48,873,492 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2754,276,934 - 54,313,887 (-)NCBISscrofa10.2Sscrofa10.2susScr3
Mthfs
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_004624941856,196 - 894,057 (-)NCBI


Expression


Sequence


Reference Sequences
RefSeq Acc Id: XM_013507694   ⟹   XP_013363148
RefSeq Status:
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_004955533720,255 - 756,893 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_013363148 (Get FASTA)   NCBI Sequence Viewer  
Reference Sequences
RefSeq Acc Id: XP_013363148   ⟸   XM_013507694
- Sequence:


Additional Information

Database Acc Id Source(s)
NCBI Gene Mthfs ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2017-01-10 Mthfs  methenyltetrahydrofolate synthetase    5,10-methenyltetrahydrofolate synthetase (5-formyltetrahydrofolate cyclo-ligase)  Symbol and/or name change 5135510 APPROVED