Dlx2 (distal-less homeobox 2) - Rat Genome Database

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Gene: Dlx2 (distal-less homeobox 2) Chinchilla lanigera
Analyze
Symbol: Dlx2
Name: distal-less homeobox 2
RGD ID: 8955793
Description: ENCODES a protein that exhibits chromatin binding (ortholog); DNA binding (ortholog); DNA-binding transcription activator activity, RNA polymerase II-specific (ortholog); INVOLVED IN branching morphogenesis of a nerve (ortholog); cartilage development (ortholog); cerebral cortex GABAergic interneuron differentiation (ortholog); ASSOCIATED WITH autistic disorder (ortholog); Craniofacial Abnormalities (ortholog); genetic disease (ortholog); FOUND IN nucleus (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: homeobox protein DLX-2
RGD Orthologs
Human
Mouse
Rat
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: ChiLan1.0 - Chinchilla ChiLan1.0 Assembly
Position:
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554492,907,436 - 2,910,816 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554492,907,502 - 2,909,893 (+)NCBIChiLan1.0ChiLan1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
nucleus  (ISO)

References

References - curated
# Reference Title Reference Citation
1. Transitive Annotation Pipeline Automated assignment of GO, PW and RDO ISO annotations across species
2. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Dlx2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554492,907,436 - 2,910,816 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554492,907,502 - 2,909,893 (+)NCBIChiLan1.0ChiLan1.0
DLX2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382172,099,438 - 172,102,900 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2172,099,438 - 172,102,900 (-)EnsemblGRCh38hg38GRCh38
GRCh372172,964,166 - 172,967,628 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 362172,672,412 - 172,675,724 (-)NCBINCBI36Build 36hg18NCBI36
Build 342172,789,673 - 172,792,773NCBI
Celera2166,580,267 - 166,583,579 (-)NCBICelera
Cytogenetic Map2q31.1NCBI
HuRef2164,844,417 - 164,847,729 (-)NCBIHuRef
CHM1_12172,971,642 - 172,974,954 (-)NCBICHM1_1
T2T-CHM13v2.02172,585,681 - 172,589,143 (-)NCBIT2T-CHM13v2.0
Dlx2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39271,373,752 - 71,377,095 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl271,373,752 - 71,377,098 (-)EnsemblGRCm39 Ensembl
GRCm38271,543,408 - 71,546,754 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl271,543,408 - 71,546,754 (-)EnsemblGRCm38mm10GRCm38
MGSCv37271,381,465 - 71,384,811 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36271,344,248 - 71,347,580 (-)NCBIMGSCv36mm8
Celera273,207,643 - 73,210,989 (-)NCBICelera
Cytogenetic Map2C2NCBI
cM Map242.65NCBI
Dlx2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8376,777,912 - 76,781,255 (-)NCBIGRCr8
mRatBN7.2356,370,238 - 56,373,581 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl356,370,483 - 56,373,597 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx359,769,269 - 59,771,154 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0368,352,878 - 68,354,763 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0366,114,992 - 66,116,877 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0358,180,088 - 58,181,971 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl358,180,088 - 58,181,971 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0364,665,449 - 64,667,332 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4353,852,209 - 53,854,092 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1353,747,472 - 53,750,805 (-)NCBI
Celera355,918,985 - 55,920,868 (-)NCBICelera
Cytogenetic Map3q23NCBI
DLX2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21374,783,594 - 74,787,065 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12B74,798,567 - 74,802,038 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02B59,396,841 - 59,400,297 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12B176,853,913 - 176,857,079 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2B176,853,913 - 176,857,079 (-)Ensemblpanpan1.1panPan2
DLX2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13616,499,009 - 16,502,365 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl3616,484,302 - 16,502,510 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha3616,508,796 - 16,511,076 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.03616,620,999 - 16,623,300 (-)NCBIROS_Cfam_1.0
UMICH_Zoey_3.13616,708,478 - 16,710,771 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.03616,708,852 - 16,711,145 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.03616,812,771 - 16,815,070 (-)NCBIUU_Cfam_GSD_1.0
Dlx2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405303133,708,086 - 133,711,491 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365092,262,873 - 2,265,391 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365092,262,873 - 2,265,391 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
DLX2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1578,200,916 - 78,204,112 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11578,200,696 - 78,204,264 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21587,651,312 - 87,654,827 (+)NCBISscrofa10.2Sscrofa10.2susScr3
DLX2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11057,604,989 - 57,609,487 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1057,606,084 - 57,608,079 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666040141,939,956 - 141,943,396 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Dlx2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247879,530,034 - 9,533,109 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247879,528,942 - 9,532,252 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence


RefSeq Acc Id: ENSCLAT00000003669   ⟹   ENSCLAP00000003595
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_0049554492,907,436 - 2,910,816 (+)Ensembl
RefSeq Acc Id: XM_005393217   ⟹   XP_005393274
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_0049554492,907,502 - 2,909,893 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_005393274 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSCLAP00000003595
  ENSCLAP00000003595.1
RefSeq Acc Id: XP_005393274   ⟸   XM_005393217
- UniProtKB: A0A8C2UNR1 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSCLAP00000003595   ⟸   ENSCLAT00000003669
Protein Domains
Homeobox


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCLAG00000002561 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCLAT00000003669 ENTREZGENE
  ENSCLAT00000003669.1 UniProtKB/TrEMBL
Gene3D-CATH Homeodomain-like UniProtKB/TrEMBL
InterPro Distal-less_N UniProtKB/TrEMBL
  Homeobox-like_sf UniProtKB/TrEMBL
  Homeobox_CS UniProtKB/TrEMBL
  Homeobox_dom UniProtKB/TrEMBL
  Homeobox_metazoa UniProtKB/TrEMBL
  HTH_motif UniProtKB/TrEMBL
NCBI Gene Dlx2 ENTREZGENE
PANTHER HOMEOBOX PROTEIN UniProtKB/TrEMBL
  HOMEOBOX PROTEIN DLX-2 UniProtKB/TrEMBL
Pfam DLL_N UniProtKB/TrEMBL
  Homeodomain UniProtKB/TrEMBL
PRINTS HOMEOBOX UniProtKB/TrEMBL
  HTHREPRESSR UniProtKB/TrEMBL
PROSITE HOMEOBOX_1 UniProtKB/TrEMBL
  HOMEOBOX_2 UniProtKB/TrEMBL
SMART HOX UniProtKB/TrEMBL
Superfamily-SCOP SSF46689 UniProtKB/TrEMBL
UniProt A0A8C2UNR1 ENTREZGENE, UniProtKB/TrEMBL