Tmtc4 (transmembrane O-mannosyltransferase targeting cadherins 4) - Rat Genome Database

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Gene: Tmtc4 (transmembrane O-mannosyltransferase targeting cadherins 4) Chinchilla lanigera
Analyze
Symbol: Tmtc4
Name: transmembrane O-mannosyltransferase targeting cadherins 4
RGD ID: 8955098
Description: ENCODES a protein that exhibits ATPase binding (ortholog); mannosyltransferase activity (ortholog); INVOLVED IN endoplasmic reticulum unfolded protein response (ortholog); outer hair cell apoptotic process (ortholog); positive regulation of endoplasmic reticulum calcium ion concentration (ortholog); ASSOCIATED WITH Anal Atresia, Hypospadias, and Penoscrotal Inversion (ortholog); holoprosencephaly (ortholog); holoprosencephaly 5 (ortholog); FOUND IN endoplasmic reticulum (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: transmembrane and tetratricopeptide repeat containing 4; transmembrane and TPR repeat-containing protein 4
RGD Orthologs
Human
Mouse
Rat
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: ChiLan1.0 - Chinchilla ChiLan1.0 Assembly
NCBI Annotation Information: Annotation category: partial on reference assembly
Position:
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540410,213,186 - 10,266,116 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495540410,213,186 - 10,266,581 (+)NCBIChiLan1.0ChiLan1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Transitive Annotation Pipeline Automated assignment of GO, PW and RDO ISS annotations to Chinchilla, Squirrel, Bonobo and/or Dog genes from Human gene annotations

Genomics

Comparative Map Data
Tmtc4
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540410,213,186 - 10,266,116 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495540410,213,186 - 10,266,581 (+)NCBIChiLan1.0ChiLan1.0
TMTC4
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh3813100,603,625 - 100,675,075 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p13 Ensembl13100,603,625 - 100,675,093 (-)EnsemblGRCh38hg38GRCh38
GRCh3713101,255,879 - 101,327,049 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 3613100,054,091 - 100,125,104 (-)NCBINCBI36hg18NCBI36
Celera1382,100,323 - 82,171,290 (-)NCBI
Cytogenetic Map13q32.3NCBI
HuRef1381,852,124 - 81,922,919 (-)NCBIHuRef
CHM1_113101,226,332 - 101,297,360 (-)NCBICHM1_1
T2T-CHM13v2.01399,818,881 - 99,890,000 (-)NCBI
Tmtc4
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3914123,156,383 - 123,220,697 (-)NCBIGRCm39mm39
GRCm39 Ensembl14123,156,383 - 123,221,447 (-)Ensembl
GRCm3814122,918,971 - 122,983,285 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl14122,918,971 - 122,984,035 (-)EnsemblGRCm38mm10GRCm38
MGSCv3714123,318,197 - 123,382,483 (-)NCBIGRCm37mm9NCBIm37
MGSCv3614122,054,155 - 122,118,441 (-)NCBImm8
Celera14121,477,235 - 121,541,523 (-)NCBICelera
Cytogenetic Map14E5NCBI
Tmtc4
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.215100,000,157 - 100,056,573 (-)NCBImRatBN7.2
mRatBN7.2 Ensembl15100,000,152 - 100,056,543 (-)Ensembl
Rnor_6.015109,338,762 - 109,394,905 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl15109,339,564 - 109,394,927 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.015112,719,672 - 112,776,171 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.415108,061,644 - 108,118,409 (-)NCBIRGSC3.4rn4RGSC3.4
Celera1598,771,432 - 98,822,061 (-)NCBICelera
Cytogenetic Map15q25NCBI
TMTC4
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.113100,910,362 - 100,976,186 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl13100,910,277 - 100,976,164 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v01381,771,668 - 81,841,926 (-)NCBIMhudiblu_PPA_v0panPan3
TMTC4
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12250,483,799 - 50,554,421 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2250,485,190 - 50,555,587 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2250,263,878 - 50,334,503 (-)NCBI
ROS_Cfam_1.02250,925,991 - 50,996,638 (-)NCBI
ROS_Cfam_1.0 Ensembl2250,926,526 - 50,996,356 (-)Ensembl
UMICH_Zoey_3.12250,572,800 - 50,643,346 (-)NCBI
UNSW_CanFamBas_1.02250,609,172 - 50,673,857 (-)NCBI
UU_Cfam_GSD_1.02250,646,448 - 50,717,077 (-)NCBI
Tmtc4
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024404945185,837,799 - 185,889,960 (-)NCBI
SpeTri2.0NW_00493647210,062,811 - 10,114,356 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
TMTC4
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1169,361,229 - 69,443,039 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11169,361,219 - 69,442,769 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21176,623,518 - 76,705,694 (-)NCBISscrofa10.2Sscrofa10.2susScr3
TMTC4
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1379,228,673 - 79,299,249 (-)NCBIChlSab1.1chlSab2
ChlSab1.1 Ensembl379,228,571 - 79,293,006 (-)EnsemblChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366604635,737,161 - 35,806,694 (-)NCBIVero_WHO_p1.0
Tmtc4
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462479310,588,037 - 10,641,260 (+)EnsemblHetGla_female_1.0hetGla2
HetGla 1.0NW_00462479310,587,703 - 10,640,634 (+)NCBIHetGla_female_1.0hetGla2


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSCLAT00000005658   ⟹   ENSCLAP00000005557
RefSeq Status:
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_00495540410,213,186 - 10,266,116 (+)Ensembl
RefSeq Acc Id: XM_013515999   ⟹   XP_013371453
RefSeq Status:
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_00495540410,213,186 - 10,266,581 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_013371453 (Get FASTA)   NCBI Sequence Viewer  
Reference Sequences
RefSeq Acc Id: XP_013371453   ⟸   XM_013515999
- Sequence:
RefSeq Acc Id: ENSCLAP00000005557   ⟸   ENSCLAT00000005658
Protein Domains
DUF1736


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCLAG00000003942 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein ENSCLAP00000005557 ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCLAT00000005658 ENTREZGENE, UniProtKB/TrEMBL
Gene3D-CATH 1.25.40.10 UniProtKB/TrEMBL
InterPro TMTC_DUF1736 UniProtKB/TrEMBL
  TPR-like_helical_dom_sf UniProtKB/TrEMBL
  TPR_repeat UniProtKB/TrEMBL
NCBI Gene Tmtc4 ENTREZGENE
Pfam DUF1736 UniProtKB/TrEMBL
  TPR_8 UniProtKB/TrEMBL
PROSITE TPR UniProtKB/TrEMBL
SMART TPR UniProtKB/TrEMBL
Superfamily-SCOP SSF48452 UniProtKB/TrEMBL
UniProt A0A8C2UZU2_CHILA UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2019-06-11 Tmtc4  transmembrane O-mannosyltransferase targeting cadherins 4  Tmtc4  transmembrane and tetratricopeptide repeat containing 4  Symbol and/or name change 5135510 APPROVED