Tnfrsf1a (TNF receptor superfamily member 1A) - Rat Genome Database

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Gene: Tnfrsf1a (TNF receptor superfamily member 1A) Chinchilla lanigera
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Symbol: Tnfrsf1a
Name: TNF receptor superfamily member 1A
RGD ID: 8954407
Description: ENCODES a protein that exhibits protease binding (ortholog); protein-containing complex binding (ortholog); tumor necrosis factor binding (ortholog); INVOLVED IN aortic valve development (ortholog); cell surface receptor signaling pathway (ortholog); cellular response to estradiol stimulus (ortholog); PARTICIPATES IN ceramide signaling pathway; nuclear factor kappa B signaling pathway; tumor necrosis factor mediated signaling pathway; ASSOCIATED WITH acne (ortholog); acquired immunodeficiency syndrome (ortholog); Acute Experimental Pancreatitis (ortholog); FOUND IN axon (ortholog); cell surface (ortholog); cytosol (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Also known as: tumor necrosis factor receptor superfamily member 1A; tumor necrosis factor receptor superfamily, member 1A
RGD Orthologs
Human
Mouse
Rat
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: ChiLan1.0 - Chinchilla ChiLan1.0 Assembly
Position:
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554133,981,400 - 3,996,021 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554133,982,670 - 3,996,320 (-)NCBIChiLan1.0ChiLan1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View
acne  (ISO)
acquired immunodeficiency syndrome  (ISO)
Acute Experimental Pancreatitis  (ISO)
acute kidney failure  (ISO)
adult respiratory distress syndrome  (ISO)
allergic bronchopulmonary aspergillosis  (ISO)
allergic disease  (ISO)
Alzheimer's disease  (ISO)
amyloidosis  (ISO)
anemia  (ISO)
Anorexia  (ISO)
Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis  (ISO)
arteriosclerosis  (ISO)
asthma  (ISO)
autoimmune disease  (ISO)
autosomal dominant familial periodic fever  (ISO)
autosomal recessive pseudohypoaldosteronism type 1  (ISO)
bacterial pneumonia  (ISO)
Behcet's disease  (ISO)
Brain Injuries  (ISO)
brain ischemia  (ISO)
bronchiectasis  (ISO)
Cachexia  (ISO)
CHARGE syndrome  (ISO)
Chronic Hepatitis C  (ISO)
chronic obstructive pulmonary disease  (ISO)
colon carcinoma  (ISO)
colorectal adenoma  (ISO)
congestive heart failure  (ISO)
coronary artery disease  (ISO)
COVID-19  (ISO)
Crohn's disease  (ISO)
cryptogenic organizing pneumonia  (ISO)
cystic fibrosis  (ISO)
cytomegalovirus retinitis  (ISO)
Diabetic Nephropathies  (ISO)
End Stage Liver Disease  (ISO)
end stage renal disease  (ISO)
endometrial cancer  (ISO)
Enterovirus Infections  (ISO)
Experimental Arthritis  (ISO)
Experimental Autoimmune Uveoretinitis  (ISO)
Experimental Colitis  (ISO)
Experimental Diabetes Mellitus  (ISO)
extrinsic allergic alveolitis  (ISO)
familial Mediterranean fever  (ISO)
Febrile Seizures  (ISO)
Fever  (ISO)
fibrosarcoma  (ISO)
focal segmental glomerulosclerosis  (ISO)
genetic disease  (ISO)
glomerulonephritis  (ISO)
Human Influenza  (ISO)
Hyperalgesia  (ISO)
Hyperoxia  (ISO)
Hyperphosphatemic Familial Tumoral Calcinosis 1  (ISO)
IgA glomerulonephritis  (ISO)
Insulin Resistance  (ISO)
ischemia  (ISO)
kidney disease  (ISO)
Kidney Reperfusion Injury  (ISO)
Legionnaires' disease  (ISO)
Liver Reperfusion Injury  (ISO)
Lung Injury  (ISO)
lung non-small cell carcinoma  (ISO)
lupus nephritis  (ISO)
Metabolic Syndrome  (ISO)
middle cerebral artery infarction  (ISO)
multiple sclerosis  (ISO)
Muscle Weakness  (ISO)
myocardial infarction  (ISO)
Nasal Polyps  (ISO)
Nematode Infections  (ISO)
Neurogenic Inflammation  (ISO)
obesity  (ISO)
obstructive sleep apnea  (ISO)
Optic Nerve Injuries  (ISO)
ovarian cancer  (ISO)
Pain  (ISO)
peroxisome biogenesis disorder 2B  (ISO)
pneumonia  (ISO)
polymyositis  (ISO)
primary biliary cholangitis  (ISO)
Pseudomonas Infections  (ISO)
psoriasis  (ISO)
Radiation Pneumonitis  (ISO)
renal cell carcinoma  (ISO)
renal fibrosis  (ISO)
Reperfusion Injury  (ISO)
retinal detachment  (ISO)
rheumatoid arthritis  (ISO)
root resorption  (ISO)
sciatic neuropathy  (ISO)
silicosis  (ISO)
Spinal Cord Compression  (ISO)
Spinal Cord Injuries  (ISO)
squamous cell carcinoma  (ISO)
systemic lupus erythematosus  (ISO)
Temtamy syndrome  (ISO)
transient cerebral ischemia  (ISO)
type 2 diabetes mellitus  (ISO)
ureteral obstruction  (ISO)
uveitis  (ISO)
visual epilepsy  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process
aortic valve development  (ISO)
cell surface receptor signaling pathway  (ISO)
cellular response to estradiol stimulus  (ISO)
cellular response to mechanical stimulus  (ISO)
cytokine-mediated signaling pathway  (ISO)
defense response  (ISO)
defense response to bacterium  (ISO)
inflammatory response  (ISO)
intrinsic apoptotic signaling pathway in response to DNA damage  (ISO)
negative regulation of apoptotic process  (ISO)
negative regulation of cardiac muscle hypertrophy  (ISO)
negative regulation of extracellular matrix constituent secretion  (ISO)
negative regulation of gene expression  (ISO)
negative regulation of inflammatory response  (ISO)
negative regulation of interleukin-6 production  (ISO)
positive regulation of angiogenesis  (ISO)
positive regulation of apoptotic process involved in morphogenesis  (ISO)
positive regulation of gene expression  (ISO)
positive regulation of I-kappaB kinase/NF-kappaB signaling  (ISO)
positive regulation of inflammatory response  (ISO)
positive regulation of neuron apoptotic process  (ISO)
positive regulation of protein import into nucleus  (ISO)
positive regulation of transcription by RNA polymerase II  (ISO)
positive regulation of tumor necrosis factor production  (ISO)
positive regulation of tyrosine phosphorylation of STAT protein  (ISO)
protein localization to plasma membrane  (ISO)
pulmonary valve development  (ISO)
regulation of apoptotic process  (ISO)
regulation of establishment of endothelial barrier  (ISO)
regulation of tumor necrosis factor-mediated signaling pathway  (ISO)
response to alkaloid  (ISO)
response to amino acid  (ISO)
response to ethanol  (ISO)
response to hypoxia  (ISO)
response to lipopolysaccharide  (ISO)
response to wounding  (ISO)
tumor necrosis factor-mediated signaling pathway  (ISO)

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References


Genomics

Comparative Map Data
Tnfrsf1a
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554133,981,400 - 3,996,021 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554133,982,670 - 3,996,320 (-)NCBIChiLan1.0ChiLan1.0
TNFRSF1A
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl126,328,757 - 6,342,114 (-)EnsemblGRCh38hg38GRCh38
GRCh38126,328,771 - 6,342,076 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh37126,437,937 - 6,451,242 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36126,308,184 - 6,321,522 (-)NCBINCBI36hg18NCBI36
Build 34126,308,184 - 6,321,522NCBI
Celera128,054,567 - 8,067,927 (-)NCBI
Cytogenetic Map12p13.31NCBI
HuRef126,291,179 - 6,304,533 (-)NCBIHuRef
CHM1_1126,437,153 - 6,450,509 (-)NCBICHM1_1
Tnfrsf1a
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm396125,326,686 - 125,339,446 (+)NCBIGRCm39mm39
GRCm39 Ensembl6125,326,325 - 125,339,447 (+)Ensembl
GRCm386125,349,723 - 125,362,483 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl6125,349,362 - 125,362,484 (+)EnsemblGRCm38mm10GRCm38
MGSCv376125,299,741 - 125,312,501 (+)NCBIGRCm37mm9NCBIm37
MGSCv366125,315,374 - 125,328,104 (+)NCBImm8
Celera6127,020,792 - 127,033,747 (+)NCBICelera
Cytogenetic Map6F3NCBI
cM Map659.32NCBI
Tnfrsf1a
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.24158,150,815 - 158,163,592 (+)NCBImRatBN7.2
Rnor_6.0 Ensembl4157,864,969 - 157,877,633 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.04157,864,905 - 157,877,634 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.04224,881,368 - 224,894,089 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.44162,172,563 - 162,185,252 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.14162,417,498 - 162,430,188 (+)NCBI
Celera4146,886,949 - 146,899,646 (+)NCBICelera
RH 3.4 Map41000.9RGD
Cytogenetic Map4q42NCBI
TNFRSF1A
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.1126,374,256 - 6,387,613 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl126,374,257 - 6,387,613 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v0126,457,617 - 6,470,969 (-)NCBIMhudiblu_PPA_v0panPan3
TNFRSF1A
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12738,641,837 - 38,654,693 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2738,638,753 - 38,700,282 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha277,959,778 - 7,972,628 (-)NCBI
ROS_Cfam_1.02738,997,951 - 39,010,819 (+)NCBI
UMICH_Zoey_3.12738,870,492 - 38,883,352 (+)NCBI
UNSW_CanFamBas_1.02738,911,954 - 38,924,837 (+)NCBI
UU_Cfam_GSD_1.0277,438,485 - 7,451,382 (-)NCBI
Tnfrsf1a
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024404945102,735,979 - 102,753,899 (+)NCBI
SpeTri2.0NW_0049367091,407,327 - 1,421,448 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
TNFRSF1A
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl564,319,073 - 64,331,909 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1564,319,349 - 64,331,876 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2566,780,726 - 66,793,255 (+)NCBISscrofa10.2Sscrofa10.2susScr3
TNFRSF1A
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1116,364,544 - 6,378,880 (-)NCBI
ChlSab1.1 Ensembl116,364,330 - 6,378,902 (-)Ensembl
Vero_WHO_p1.0NW_0236660631,856,767 - 1,871,090 (+)NCBI
Tnfrsf1a
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046248603,111,244 - 3,123,041 (-)NCBI


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSCLAT00000023675   ⟹   ENSCLAP00000023454
RefSeq Status:
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_0049554133,981,400 - 3,996,021 (-)Ensembl
RefSeq Acc Id: XM_005378759   ⟹   XP_005378816
RefSeq Status:
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_0049554133,982,670 - 3,996,320 (-)NCBI
Sequence:
RefSeq Acc Id: XM_013511327   ⟹   XP_013366781
RefSeq Status:
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_0049554133,982,670 - 3,995,586 (-)NCBI
Sequence:
RefSeq Acc Id: XM_013511328   ⟹   XP_013366782
RefSeq Status:
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_0049554133,982,670 - 3,988,900 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_005378816 (Get FASTA)   NCBI Sequence Viewer  
  XP_013366781 (Get FASTA)   NCBI Sequence Viewer  
  XP_013366782 (Get FASTA)   NCBI Sequence Viewer  
Reference Sequences
RefSeq Acc Id: XP_005378816   ⟸   XM_005378759
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_013366781   ⟸   XM_013511327
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: XP_013366782   ⟸   XM_013511328
- Peptide Label: isoform X3
- Sequence:
RefSeq Acc Id: ENSCLAP00000023454   ⟸   ENSCLAT00000023675


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCLAG00000016084 Ensembl, ENTREZGENE
Ensembl Protein ENSCLAP00000023454 ENTREZGENE
Ensembl Transcript ENSCLAT00000023675 ENTREZGENE
NCBI Gene Tnfrsf1a ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-08-03 Tnfrsf1a  TNF receptor superfamily member 1A    tumor necrosis factor receptor superfamily, member 1A  Symbol and/or name change 5135510 APPROVED